[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650484":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":11,"centralContacts":11,"locations":38,"responsibleParty":57,"collaborators":11,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":11,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":11,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":11,"overallStatus":40,"whyStopped":11,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Active tDCS and yoga","ACTIVE_COMPARATOR",null,[13,14],"Device: Active tDCS","Behavioral: Yoga",{"label":16,"type":17,"description":11,"interventionNames":18},"Sham tDCS and yoga","SHAM_COMPARATOR",[19,14],"Device: Sham tDCS",{"label":21,"type":22,"description":11,"interventionNames":11},"Waitlist control group","NO_INTERVENTION",[24,29,33],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"DEVICE","Active tDCS","Active tDCS will be applied using a wearable stimulator (LifTid) with a constant stimulation intensity of 1.2 mA for 20 minutes. The device has been designed for anodal stimulation targeting DLPFC using the F3 (anode) to F4 (cathode) montage.",[9],{"type":25,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"Sham tDCS","Sham tDCS will be performed using the same device but without stimulation. During the yoga training, all participants will wear the device and a facilitator will turn on the stimulation for participants receiving a-tDCS-Y intervention, and pretend to turn on the stimulation for participants receiving s-tDCS-Y intervention after the first 10-minute section.",[16],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":11},"BEHAVIORAL","Yoga","Yoga will be based on the basic theory and research of the foundation of Hatha yoga. Participants will cultivate the learning of yoga through various kinds of activity, such as breathing control, body postures, and relaxation. The yoga is designed to create an overall effect on the body and mind through strength training and stretching with a mindful sensation. Each 1-hour intervention session contains reviewing the last week self-practice, breathing practice and warm-up (10 minutes), posture sequences (40 minutes), relaxation (5 minutes), reflection and feedback (5 minutes). Video clips will be provided through social media apps (i.e., WhatsApp, WeChat) to enable home-based practice at least twice weekly. A logbook will be distributed to the participants for their record of self-practice and will be reviewed weekly by the intervention facilitator.",[9,16],[39],{"facility":5,"status":40,"city":41,"state":42,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Hung Hom","Kowloon","Hong Kong","HK",{"type":46,"coordinates":47},"Point",[48,49],114.18532,22.30715,{"lat":49,"lon":48},[52],{"name":53,"role":54,"phone":55,"phoneExt":11,"email":56},"Prof. Jessie LIN","CONTACT","+85227666718","jx-jessie.lin@polyu.edu.hk",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","LIN Jingxia Jessie","Assistant Professor","100650484","the-effect-of-combined-brain-stimulation-and-yoga-for-improving-cognitive-function-in-psychosis-100650484",false,"NCT07747181","The Effect of Combined Brain Stimulation and Yoga for Improving Cognitive Function in Psychosis","Yoga and tDCS to Improve Cognitive Function in Individuals With Psychosis: A Pragmatic Controlled Trial","Inclusion Criteria:\n\n* (1) aged 18 to 65 years\n* (2) diagnosis based on SCID for schizophrenia and related disorders, psychosis, and delusional disorder with the positive symptom measured by CGI ≤ 3\n* (3) ability to understand the nature of the study and to give informed consent (The MacArthur Competence Assessment Tool for Clinical Research score ≥ 35)\n* (4) Chinese-speaking\n* (5) fewer than 10 hours of yoga and other mind-body intervention (e.g., Tai Chi, Qigong, Mindfulness) in the previous 3 months.\n\nExclusion Criteria:\n\n* (1) Severe physical diseases, such as myocardial infarction, uncontrollable severe hypertension, fracture, severe spinal problems, or contraindication for exercise\n* (2) comorbid substance dependence and seizure disorders\n* (3) pregnancy or other contraindication to fNIRS\n* (4) known history of intellectual disability or special school attendance, brain trauma, or organic brain disease\n* (5) Individuals taking Benzodiazepine will still be recruited in the project, and will be excluded from the fNIRS measure.","ALL","18 Years","65 Years",{"count":72,"type":73},135,"ESTIMATED","INTERVENTIONAL",[76],"NA","The study examines (1) the effects of active anodal (facilitatory) tDCS and yoga combined intervention on cognitive function, clinical symptoms, and quality of life domains (social function and physical wellbeing) in psychosis, and (2) the neurophysiological mechanisms underlying the effects induced by the combined intervention.",[79,80],"Cognitive Functioning","Psychosis","2026-08-04",{"date":83,"type":84},"2026-08-05","ACTUAL",{"date":86,"type":84},"2026-01-01",{"date":88,"type":73},"2028-06-30",{"name":5,"class":6},1]