[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646399":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":30,"locations":36,"responsibleParty":52,"collaborators":29,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":29,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":39,"whyStopped":29,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Copenhagen","OTHER",[8,14,17,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Young normal weight men","EXPERIMENTAL","BMI \\[18, 25\\] Age \\[18, 40\\]",[13],"Other: Diet",{"label":15,"type":10,"description":11,"interventionNames":16},"Young normal weight women",[13],{"label":18,"type":10,"description":19,"interventionNames":20},"Young obese men","BMI \\[30, 40\\] Age \\[18, 40\\]",[13],{"label":22,"type":10,"description":19,"interventionNames":23},"Young obese women",[13],[25],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Diet","Long-term fasting (84 hours), physiological testing before and after fasting: sampling of blood, abdominal adipose tissue and skeletal muscle for molecular analysis and respiratory measurements at rest.",[9,15,18,22],null,[31],{"name":32,"role":33,"phone":34,"phoneExt":29,"email":35},"Jørn W Helge, PhD","CONTACT","+4528757506","jhelge@sund.ku.dk",[37],{"facility":38,"status":39,"city":40,"state":29,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Department of Biomedical Sciences","RECRUITING","Copenhagen","2200","Denmark","DK",{"type":45,"coordinates":46},"Point",[47,48],12.56553,55.67594,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":34,"phoneExt":29,"email":35},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Jørn Wulff Helge","Professor","100646399","the-effect-of-fasting-on-peak-fat-oxidation-mitochondrial-coupling-and-extracellular-matrix-100646399",false,"NCT07692646","The Effect of Fasting on Peak Fat Oxidation, Mitochondrial Coupling and Extracellular Matrix","The Effect of Fasting on Peak Fat Oxidation, Mitochondrial Coupling and Extracellular Matrix in Healthy Men and Lean and Obese Men and Women","GlycoFast84","Inclusion Criteria:\n\n* Healthy normal weight men aged \\[18,40\\] and BMI \\[18,25\\]\n* Healthy normal weight women \\[18,40\\] and BMI \\[18,25\\]\n* Healthy obese men \\[18,40\\] and BMI \\[30,40\\]\n* Healthy obese women \\[18,40\\] and BMI \\[30,40\\]\n\nExclusion Criteria:\n\n* Present or former cardiovascular disease and chronical inflammatory disease\n* Consumption of medications and supplements that influence substrate use at rest and\u002For during exercise\n* Pregnancy",true,"ALL","18 Years","40 Years",{"count":69,"type":70},40,"ESTIMATED","INTERVENTIONAL",[73],"NA","The interventional study will recruit four groups (n=10 per group): Young men and women with normal weight (BMI 18-25), and young men and women with obesity (BMI \\>30). The study will investigate the effect of 84 hours of fasting on peak fat oxidation, mitochondrial coupling and the extracellular matrix.",[76,77,78],"Fasting","Obesity (BMI>30)","Sex Difference",[80,81,82,83],"Muscle metabolism","Mitochondrial coupling","Extracellular matrix composition","Peak fat oxidation","2026-07-02",{"date":86,"type":87},"2026-07-09","ACTUAL",{"date":89,"type":70},"2026-06",{"date":91,"type":70},"2033-12",{"name":5,"class":6},1]