[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657571":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":29,"studyPopulation":20,"armGroups":30,"interventions":41,"overallOfficials":47,"centralContacts":51,"locations":59,"responsibleParty":76,"collaborators":20,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":20,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":62,"whyStopped":20,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"University of Gaziantep","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":20},[9,13],{"measure":10,"description":11,"timeFrame":12},"Fatigue severity measured by the FACIT-Fatigue Scale","Fatigue will be assessed using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) Scale. Changes in fatigue scores from baseline to post-intervention assessment will be evaluated between the intervention and control groups.","Baseline and 4 weeks after the intervention",{"measure":14,"description":15,"timeFrame":12},"Dyspnea severity measured by the Dyspnea-12 (D-12) Scale","Dyspnea will be assessed using the Dyspnea-12 (D-12) Scale. Changes in dyspnea scores from baseline to post-intervention assessment will be evaluated between the intervention and control groups.",[17],{"measure":18,"description":19,"timeFrame":12},"Respiratory function measured by forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC)","Respiratory function will be assessed using spirometry, including forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC). Changes in FEV1 and FVC from baseline to post-intervention assessment will be evaluated between the intervention and control groups.",null,{"allocation":22,"interventionModel":23,"interventionModelDescription":24,"primaryPurpose":25,"observationalModel":20,"timePerspective":20,"maskingInfo":26},"RANDOMIZED","PARALLEL","Participants will be randomly assigned to either the progressive muscle relaxation exercise group or the control group. The intervention group will receive progressive muscle relaxation exercises, while the control group will receive standard care. Outcomes will be assessed and compared between the two groups before and after the intervention.","SUPPORTIVE_CARE",{"masking":27,"maskingDescription":28,"whoMasked":20},"NONE","Participants and outcome assessors are blinded to group allocation. The researcher administering the intervention is aware of the group allocation.","Systemic sclerosis is a chronic autoimmune connective tissue disease that can affect multiple organs, including the respiratory system. Respiratory involvement may lead to symptoms such as dyspnea and fatigue and may adversely affect respiratory function and quality of life.\n\nProgressive muscle relaxation exercise is a non-pharmacological relaxation technique that involves systematically tensing and relaxing different muscle groups. This technique may reduce physical and psychological tension and may contribute to the management of symptoms such as fatigue and dyspnea.\n\nThe purpose of this study is to evaluate the effect of progressive muscle relaxation exercises on fatigue, dyspnea, and respiratory function in patients with systemic sclerosis. Participants will undergo baseline assessments before the intervention. Progressive muscle relaxation exercises will then be administered, followed by post-intervention assessments to determine changes in fatigue, dyspnea, and respiratory function.\n\nThe findings of this study may provide evidence regarding the potential use of progressive muscle relaxation exercises as a supportive non-pharmacological intervention for symptom management in patients with systemic sclerosis.",[31,37],{"label":32,"type":33,"description":34,"interventionNames":35},"Progressive Muscle Relaxation Exercise Group","EXPERIMENTAL","Participants randomly assigned to this group will receive progressive muscle relaxation exercises in addition to standard care.",[36],"Behavioral: Progressive Muscle Relaxation Exercise",{"label":38,"type":39,"description":40,"interventionNames":20},"Control Group","NO_INTERVENTION","Participants randomly assigned to this group will receive standard care without progressive muscle relaxation exercises.",[42],{"type":43,"name":44,"description":45,"armGroupLabels":46,"otherNames":20},"BEHAVIORAL","Progressive Muscle Relaxation Exercise","Participants in the intervention group will receive progressive muscle relaxation exercises according to the study protocol. The intervention will be administered in addition to standard care.",[32],[48],{"name":49,"affiliation":5,"role":50},"Adile Neşe, Associate Professor","PRINCIPAL_INVESTIGATOR",[52,57],{"name":53,"role":54,"phone":55,"phoneExt":20,"email":56},"Adile Neşe, Assoc Prof.","CONTACT","03423172187","acaparusagi@hotmail.com",{"name":58,"role":54,"phone":55,"phoneExt":20,"email":56},"Adile Neşe, Assoc Prof",[60],{"facility":61,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":20,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"Gaziantep University Vocational School of Health Services","RECRUITING","Gaziantep","Şehitkamil","27000","Turkey (Türkiye)",{"type":68,"coordinates":69},"Point",[70,71],37.3825,37.05944,{"lat":71,"lon":70},[74,75],{"name":49,"role":54,"phone":55,"phoneExt":20,"email":56},{"name":49,"role":54,"phone":20,"phoneExt":20,"email":20},{"type":50,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Adile Nese","Assistant Professor","100657571","the-effect-of-progressive-muscle-relaxation-exercises-on-fatigue-dyspnea-and-respiratory-function-in-patients-with-systemic-sclerosis-100657571",false,"NCT07842133","The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic Sclerosis","The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic Sclerosis: A Randomized Controlled Trial","PMR-SCLERODERM","Inclusion Criteria:Individuals who meet the study eligibility criteria will be included in the study. Eligible participants will be adults aged 18 years or older, diagnosed with systemic sclerosis, and have adequate physical and cognitive capacity to participate in the study.\n\nExclusion Criteria:Individuals who do not meet the inclusion criteria, who are unable to participate in the progressive muscle relaxation exercises due to their physical or cognitive condition, or who withdraw from the study voluntarily will be excluded from the study.\n\n\\-","ALL","18 Years","65 Years",{"count":91,"type":92},50,"ESTIMATED","INTERVENTIONAL",[95],"NA","This study aims to evaluate the effects of progressive muscle relaxation exercises on fatigue, dyspnea, and respiratory function in patients with systemic sclerosis. Participants will be assessed before and after the intervention.",[98],"Systemic Sclerosis (SSc)",[100],"Systemic sclerosis; Scleroderma; Progressive muscle relaxation; Fatigue; Dyspnea;","2026-10-05",{"date":103,"type":104},"2026-10-08","ACTUAL",{"date":106,"type":104},"2026-04-25",{"date":108,"type":92},"2026-12-25",{"name":5,"class":6},1]