[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647899":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":32,"locations":11,"responsibleParty":42,"collaborators":11,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":11,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":11,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":68,"whyStopped":11,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":11},{"fullName":5,"class":6},"Balikesir University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Laura Mitchell Exercises","EXPERIMENTAL",null,[13],"Other: Standard Mitchell Relaxation Exercise",{"label":15,"type":10,"description":11,"interventionNames":16},"Modified Mitchell Exercises",[17],"Other: Modified Mitchell Relaxation Exercises",[19,23],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"Modified Mitchell Relaxation Exercises","Modified Relaxation Exercises based on Muscle Energy Technique, Deep Breathing, Additional Natural Relxation Postures in addition Skin and Proprioceptive Awareness and Reciprocal Mussle .",[15],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Standard Mitchell Relaxation Exercise","Original Relaxation Exercises based on Skin and Proprioceptive Awareness and Reciprocal Mussle Inhibition",[9],[28,29,30,31],"Simple Relaxation","Physiologic Relaxation Technique","Simple Relaxation Technique","Simple Relaxation Exercise",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":11,"email":37},"Utku Berberoğlu, Assistant Professor","CONTACT","+905052017066","utku.berberoglu@balikesir.edu.tr",{"name":39,"role":35,"phone":40,"phoneExt":11,"email":41},"Dilek Işık, MsC","+905372569963","caldilek10@gmail.com",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Utku Berberoğlu","assistant professor","100647899","the-effect-of-the-modified-mitchell-relaxation-method-on-acute-cardiac-autonomic-modulation-100647899",false,"NCT07713407","The Effect of the Modified Mitchell Relaxation Method on Acute Cardiac Autonomic Modulation","Inclusion Criteria:\n\n* Being 18-65 years old.\n* Having stress and anxiety\n\nExclusion Criteria:\n\n* Taking cardioactive\u002Fpsychotropic drugs.\n* Having a diagnosis of cardiovascular disease.",true,"ALL","18 Years","65 Years",{"count":57,"type":58},122,"ESTIMATED","INTERVENTIONAL",[61],"NA","The purpose of this multi-center, randomized controlled trial is to investigate the acute effects of the standard Laura Mitchell Physiological Relaxation Method versus a Modified Mitchell Relaxation Version on cardiac autonomic modulation (heart rate variability). The study will include 122 participants aged 18-65 who score 10 or higher on the Generalized Anxiety Disorder-7 (GAD-7) scale, indicating high anxiety and potentially reduced parasympathetic control. Participants will be randomly allocated into two equal groups (n=61 per group) using a block randomization system with a concealed envelope method. To control for expectation bias, an incomplete disclosure protocol will be utilized, ensuring participants remain blinded to their specific group allocation. Both interventions will last 35 minutes and will be delivered via audio recordings in a supine position (Mitchell's 'Position A') to prevent investigator bias. Cardiac autonomic responses will be assessed using a Polar H10 chest strap to analyze Heart Rate Variability (HRV) before, during, and after the sessions. Blood pressure and respiration rate will also be monitored as secondary outcomes",[64],"Stress and Anxiety",[66,67],"laura mitchell","relaxation exercises","NOT_YET_RECRUITING","2026-07-16",{"date":71,"type":72},"2026-07-20","ACTUAL",{"date":74,"type":58},"2026-07-01",{"date":76,"type":58},"2028-07-01",{"name":5,"class":6}]