[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658032":3},{"organization":4,"outcomesModule":7,"designInfo":20,"detailedDescription":27,"studyPopulation":19,"armGroups":28,"interventions":41,"overallOfficials":49,"centralContacts":54,"locations":63,"responsibleParty":83,"collaborators":19,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":89,"sex":95,"minAge":96,"maxAge":19,"enrollmentInfo":97,"targetDuration":19,"studyType":100,"phases":101,"briefSummary":103,"conditions":104,"keywords":19,"overallStatus":66,"whyStopped":19,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Vrije Universiteit Brussel","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":19},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"NRPS Pain score","numeric pain rating scale","6 weeks",{"measure":14,"description":15,"timeFrame":12},"PSPF","Patient Specific Functional Scale",{"measure":17,"description":18,"timeFrame":12},"oxidative stress bloodmarkers","d-Roms fast test",null,{"allocation":21,"interventionModel":22,"interventionModelDescription":23,"primaryPurpose":24,"observationalModel":19,"timePerspective":19,"maskingInfo":25},"RANDOMIZED","PARALLEL","randomised 2 group study","TREATMENT",{"masking":26,"maskingDescription":19,"whoMasked":19},"NONE","In this study you will be part of a group one that receives 6 weeks of training (2 sessions per week) or you are part of group two that will exercise by walking 6000 steps per day.\n\nTo investigate the effect of the training and walking, there will be an first screening of your capillary blood (by use of a few drops of blood from your finger), and you will be asked to fill in some questionnaires about your symptoms, that will include a painscore and a questionair on your specific complaints. These test will be retaken at the end of your 6 weeks of training.\n\nThe study is focussed to benefit you by strengthening the muscles around your knee and improving your overall fitness.",[29,35],{"label":30,"type":31,"description":32,"interventionNames":33},"supervised training","EXPERIMENTAL","the patient will recieve 6 weeks of 2 supevised trainings per week as an outpatient",[34],"Other: supervised training",{"label":36,"type":37,"description":38,"interventionNames":39},"walking","ACTIVE_COMPARATOR","the patient will walk 6000 steps per day for the duration of 6 weeks",[40],"Other: daily walking",[42,45],{"type":6,"name":30,"description":43,"armGroupLabels":44,"otherNames":19},"supervised training by a trained physical therapist, focussed on strength and overall fitness",[30],{"type":6,"name":46,"description":47,"armGroupLabels":48,"otherNames":19},"daily walking","walking 6000 steps per day unsupervised",[36],[50],{"name":51,"affiliation":52,"role":53},"Aldo Scafoglieri, Prof","professor at VUB","PRINCIPAL_INVESTIGATOR",[55,60],{"name":56,"role":57,"phone":58,"phoneExt":19,"email":59},"Mariette boshuis-scheenstra","CONTACT","+31102847365","Mariette@rozenburcht.com",{"name":61,"role":57,"phone":58,"phoneExt":19,"email":62},"boudewijn Scheenstra","fysio@rozenburcht.com",[64],{"facility":65,"status":66,"city":67,"state":19,"zip":68,"country":69,"countryCode":70,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"Fysiotherapie de Rozenburcht","RECRUITING","Capelle aan den IJssel","2902BW","Netherlands","NL",{"type":72,"coordinates":73},"Point",[74,75],4.57778,51.92917,{"lat":75,"lon":74},[78,80,81],{"name":79,"role":57,"phone":58,"phoneExt":19,"email":59},"Mariette boshuis-scheenstra, Manual therapist",{"name":61,"role":57,"phone":58,"phoneExt":19,"email":62},{"name":56,"role":82,"phone":19,"phoneExt":19,"email":19},"SUB_INVESTIGATOR",{"type":84,"investigatorFullName":85,"investigatorTitle":86,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"SPONSOR_INVESTIGATOR","Mariette Boshuis","Physical and Manual therapist","100658032","the-effect-of-training-on-oxidative-stress-in-patients-with-kneeoa-100658032",false,"NCT07845838","The Effect of Training on Oxidative Stress in Patients With kneeOA.","The Effect of Training on Oxidative Stress in Patients With Osteoarthritis of the Knee. A Study of the Effects of Supervised Exercise Therapy on Oxidative Stress.","24008_Protarth","Inclusion Criteria:\n\n* diagnosed Knee osteoartritis in one or both knees\n\nExclusion Criteria:\n\n* not able to walk 6000 steps\n* not able to participate in the training","ALL","18 Years",{"count":98,"type":99},20,"ESTIMATED","INTERVENTIONAL",[102],"NA","A six week patient study that intends to prove that training helps improve the life of people with osteoatritis of the knee.\n\nIt looks at pain and function in daily life and markers in the blood that show stress at a cell level.",[105,106],"Knee Osteoarthritis","Oxidative Stress","2026-09-21",{"date":109,"type":110},"2026-09-29","ACTUAL",{"date":112,"type":110},"2025-05-05",{"date":114,"type":99},"2027-06-01",{"name":85,"class":6},1]