[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650181":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":10,"responsibleParty":21,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":79,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":10},{"fullName":5,"class":6},"Chinese PLA General Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Depression group",null,"Patients with PHQ-9 scores greater than 5, indicating mild to severe depressive symptoms before surgery.",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-depression group","Patients with PHQ-9 scores less than 5, indicating minimal or no depressive symptoms before surgery",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Chen Cai","CONTACT","+8613718718781","1607125811@qq.com",{"type":22,"investigatorFullName":23,"investigatorTitle":24,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Weidong Mi","Associate Chief Physician",[26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56],{"name":27,"class":6},"Beijing Tsinghua Changgeng Hospital",{"name":29,"class":6},"Peking University First Hospital",{"name":31,"class":6},"The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School",{"name":33,"class":6},"Xiangya Hospital of Central South University",{"name":35,"class":6},"Beijing Anzhen Hospital",{"name":37,"class":6},"Central South University",{"name":39,"class":6},"Peking University People's Hospital",{"name":41,"class":6},"Zhejiang University",{"name":43,"class":6},"Fudan University",{"name":45,"class":6},"Sun Yat-sen University",{"name":47,"class":6},"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology",{"name":49,"class":6},"China-Japan Friendship Hospital",{"name":51,"class":6},"The Affiliated Hospital Of Guizhou Medical University",{"name":53,"class":6},"First Affiliated Hospital of Xinjiang Medical University",{"name":55,"class":6},"First Affiliated Hospital of Guangxi Medical University",{"name":57,"class":6},"Taihe Hospital","100650181","the-impact-of-preoperative-depression-on-postoperative-delirium-in-elderly-chinese-patients-a-retrospective-multicenter-observational-study-100650181",false,"NCT07744282","The Impact of Preoperative Depression on Postoperative Delirium in Elderly Chinese Patients: A Retrospective Multicenter Observational Study","Preoperative Depression and Postoperative Delirium in Older Chinese Adults: A Multicenter Retrospective Cohort Study","Inclusion Criteria:\n\n* 1\\. Age ≥ 65 years, both genders 2. Elective non-cardiac major surgery 3. Completed preoperative depression assessment (PHQ-9) 4. Completed postoperative delirium assessment (3D-CAM)\n\nExclusion Criteria:\n\n* 1\\. History of neurological or psychiatric disorders or use of neuropsychiatric medications 2. Impaired cognitive function or inability to complete preoperative follow-up 3. Transferred to ICU postoperatively 4. Missing delirium outcome data","ALL","65 Years","100 Years",{"count":69,"type":70},8000,"ESTIMATED","OBSERVATIONAL","This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of preoperative depression on the incidence of postoperative delirium among elderly Chinese patients undergoing non-cardiac major surgery.",[74],"Cohort Studies",[76,77,78],"Depression","Postoperative Delirium","Non-cardiac major surgery","NOT_YET_RECRUITING","2026-08-01",{"date":82,"type":83},"2026-08-04","ACTUAL",{"date":85,"type":70},"2026-08-15",{"date":87,"type":70},"2027-03-01",{"name":5,"class":6}]