[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646114":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":10,"responsibleParty":29,"collaborators":10,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":10,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":10,"studyType":44,"phases":10,"briefSummary":45,"conditions":46,"keywords":10,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":10},{"fullName":5,"class":6},"Shengjing Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Hypertonia Group",null,"Patients with lower extremity hypertonia, defined as a Modified Ashworth Scale (MAS) score of 1 or higher at admission.",{"label":13,"type":10,"description":14,"interventionNames":10},"Normal Tone Group","Patients with normal lower extremity muscle tone, defined as a Modified Ashworth Scale (MAS) score of 0 at admission.",[16],{"name":17,"affiliation":18,"role":19},"Xue Jiang","Rehabilitation Center of Shengjing Hospital, China Medical University","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+86 18940254064","jiangxueruby@163.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Siyan Lu","+86 15998390096","940436682@qq.com",{"type":19,"investigatorFullName":17,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Associate Professor","100646114","the-predictive-value-of-lower-extremity-hypertonia-on-neurogenic-detrusor-overactivity-after-spinal-cord-injury-100646114",false,"NCT07695662","The Predictive Value of Lower Extremity Hypertonia on Neurogenic Detrusor Overactivity After Spinal Cord Injury","The Predictive Value of Increased Lower Limb Muscle Tone on Neurogenic Detrusor Overactivity in Patients With Spinal Cord Injury: A Retrospective Analysis","Inclusion Criteria:\n\nDiagnosis of spinal cord injury confirmed by CT or MRI imaging\n\nSuprasacral spinal cord injury according to the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI, 2011 revision)\n\nAge between 18 and 80 years\n\nComplete medical records, including detailed neurological examination, Modified Ashworth Scale assessment, and urodynamic study report\n\nExclusion Criteria:\n\nCritical missing information in medical records or urodynamic reports\n\nInterval between Modified Ashworth Scale assessment and urodynamic study exceeding 2 weeks","ALL","16 Years","80 Years",{"count":42,"type":43},300,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate whether increased lower extremity muscle tone can serve as an independent predictor of neurogenic detrusor overactivity (NDO) in adult patients (aged 18-80 years) with upper sacral spinal cord injury .\n\nThe main questions it aims to answer are:\n\nIs increased lower extremity muscle tone independently associated with the presence of detrusor overactivity after adjusting for age, sex, injury level, injury type, and injury cause?\n\nDoes the predictive value of muscle tone for detrusor overactivity differ across subgroups defined by injury level, injury severity, and time since injury?\n\nResearchers will compare patients with lower extremity hypertonia (Modified Ashworth Scale ≥ 1) to patients with normal muscle tone (Modified Ashworth Scale = 0) to see if muscle tone elevation independently predicts detrusor overactivity.\n\nParticipants will not be asked to do anything beyond their routine clinical care, as this is a retrospective study that only collects data from existing medical records, including neurological examination results, Modified Ashworth Scale scores, and urodynamic study reports.",[47],"Spinal Cord Injuries (SCI)","NOT_YET_RECRUITING","2026-07-09",{"date":51,"type":52},"2026-07-10","ACTUAL",{"date":54,"type":43},"2026-07-07",{"date":56,"type":43},"2027-06-14",{"name":5,"class":6}]