[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656335":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":21,"interventions":38,"overallOfficials":13,"centralContacts":13,"locations":52,"responsibleParty":72,"collaborators":74,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":13,"eligibilityCriteria":85,"healthyVolunteers":82,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":13,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":13,"overallStatus":54,"whyStopped":13,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"SRI International","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Number of hot flashes","Number of hot flashes, based on sternal skin conductance measurement","Across the ~5 hour experimental period in the lab",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":18,"observationalModel":13,"timePerspective":13,"maskingInfo":19},"RANDOMIZED","CROSSOVER","There are three temperature interventions, each participant may be exposed to during the study: room temperature, ambient cooling, targeted skin cooling","BASIC_SCIENCE",{"masking":20,"maskingDescription":13,"whoMasked":13},"NONE",[22,30,34],{"label":23,"type":24,"description":25,"interventionNames":26},"Sequence A-B-C","EXPERIMENTAL","Laboratory interventions are administered in the order of Room Temperature-Ambient Cooling-Targeted skin cooling",[27,28,29],"Other: Intervention C (Targeted skin cooling)","Other: Intervention B (Ambient cooling)","Other: Intervention A (Room temperature)",{"label":31,"type":24,"description":32,"interventionNames":33},"Sequence B-C-A","Laboratory interventions are administered in order of Ambient cooling-Targeted skin cooling-Room temperature",[27,28,29],{"label":35,"type":24,"description":36,"interventionNames":37},"Sequence C-A-B","Laboratory interventions are administered in the order of Targeted skin cooling-Room temperature-Ambient cooling",[27,28,29],[39,44,48],{"type":40,"name":41,"description":42,"armGroupLabels":43,"otherNames":13},"OTHER","Intervention C (Targeted skin cooling)","Cooling targeted to the skin during a hot flash",[23,31,35],{"type":40,"name":45,"description":46,"armGroupLabels":47,"otherNames":13},"Intervention B (Ambient cooling)","Cooling of the room",[23,31,35],{"type":40,"name":49,"description":50,"armGroupLabels":51,"otherNames":13},"Intervention A (Room temperature)","Control condition (room temperature)",[23,31,35],[53],{"facility":5,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"RECRUITING","Menlo Park","California","94025-3453","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-122.18219,37.45383,{"lat":64,"lon":63},[67],{"name":68,"role":69,"phone":70,"phoneExt":13,"email":71},"Fiona Baker","CONTACT","6508593062","fiona.baker@sri.com",{"type":73,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR",[75,78],{"name":76,"class":77},"National Institute on Aging (NIA)","NIH",{"name":79,"class":40},"Stanford University","100656335","thermoregulatory-physiology-of-menopausal-hot-flashes-100656335",false,"NCT07824648","Thermoregulatory Physiology of Menopausal Hot Flashes","Inclusion Criteria:\n\n* Female\n* Age range: 40 to 65 years and in menopausal transition or post-menopause;\n* At least 8 years of education to ensure adequate reading proficiency;\n* Primary language is English or Spanish.\n\nExclusion Criteria:\n\n* History of medical or neurological illness or trauma that would affect the central nervous system (e.g., stroke, multiple sclerosis, epilepsy);\n* Current severe medical conditions (e.g. Diabetes, cancer, cardiovascular disease, renal or hepatic disease, thyroid disorders);\n* History of schizophrenia and\u002For bipolar disorder;\n* Dependence or abuse of illicit substances in the past year;\n* Current use of hormone therapy or other treatments for hot flash symptoms","FEMALE","40 Years","65 Years",{"count":90,"type":91},40,"ESTIMATED","INTERVENTIONAL",[94],"NA","This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.",[97],"Menopause Hot Flashes","2026-09-11",{"date":100,"type":101},"2026-09-17","ACTUAL",{"date":103,"type":101},"2026-05-05",{"date":105,"type":91},"2027-09-15",{"name":5,"class":6},1]