[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596677":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":24,"responsibleParty":219,"collaborators":222,"id":227,"slug":228,"hasResults":229,"nctId":230,"briefTitle":231,"officialTitle":231,"acronym":232,"eligibilityCriteria":233,"healthyVolunteers":229,"sex":234,"minAge":235,"maxAge":236,"enrollmentInfo":237,"targetDuration":10,"studyType":240,"phases":10,"briefSummary":241,"conditions":242,"keywords":244,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":261},{"fullName":5,"class":6},"State University of New York at Buffalo","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Preschool \u002F Early Childhood Group (18 mos - 5 years)",null,"300 children with CF and their parents will be recruited. This cohort will help identify early signs of internalizing and externalizing behaviors, attention-related concerns, and the impact of CF treatments on psychosocial health.\n\nChildren in this cohort may also be identified for participation in Aim 3 if they are on or eligible for modulator therapy.",{"label":13,"type":10,"description":14,"interventionNames":10},"School-Age Group (6 - 11 years)","300 children with CF and their parents will be recruited. Includes school-aged children who can self-report their emotional and behavioral health, beginning at age 8 years.\n\nThis group will be assessed for emerging mental health symptoms, cognitive development, and procedural anxiety related to CF treatments.\n\nChildren in this cohort may also be identified for participation in Aim 3 if they are on or eligible for modulator therapy.",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Beth A Smith, MD","CONTACT","716-898-5940","balucas@buffalo.edu",{"name":22,"role":18,"phone":10,"phoneExt":10,"email":23},"Minu Mohan, MPH","minuponn@buffalo.edu",[25,44,59,74,88,103,118,133,148,163,174,189,204],{"facility":26,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Children's Hospital of Orange County","RECRUITING","Orange","California","92868","United States","US",{"type":34,"coordinates":35},"Point",[36,37],-117.85311,33.78779,{"lat":37,"lon":36},[40],{"name":41,"role":18,"phone":42,"phoneExt":10,"email":43},"Adrianne Alpern, PhD","657-767-2730","aalpern@choc.org",{"facility":45,"status":27,"city":46,"state":47,"zip":48,"country":31,"countryCode":32,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Children's Hospital Colorado","Aurora","Colorado","80045",{"type":34,"coordinates":50},[51,52],-104.83192,39.72943,{"lat":52,"lon":51},[55],{"name":56,"role":18,"phone":57,"phoneExt":10,"email":58},"Emily Muther, PhD","720- 777-3257","Emily.Muther@childrenscolorado.org",{"facility":60,"status":27,"city":61,"state":62,"zip":63,"country":31,"countryCode":32,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Joe DiMaggio","Hollywood","Florida","33021",{"type":34,"coordinates":65},[66,67],-80.14949,26.0112,{"lat":67,"lon":66},[70],{"name":71,"role":18,"phone":72,"phoneExt":10,"email":73},"Alexandra L Quittner, PhD","305-992-2411","aquittner@mhs.net",{"facility":75,"status":27,"city":76,"state":62,"zip":77,"country":31,"countryCode":32,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Nemours Foundation","Orlando","32827",{"type":34,"coordinates":79},[80,81],-81.37924,28.53834,{"lat":81,"lon":80},[84],{"name":85,"role":18,"phone":86,"phoneExt":10,"email":87},"David Fedele, PhD","352-294-5765","David.Fedele@nemours.org",{"facility":89,"status":27,"city":90,"state":91,"zip":92,"country":31,"countryCode":32,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Indiana University","Bloomington","Indiana","47405",{"type":34,"coordinates":94},[95,96],-86.52639,39.16533,{"lat":96,"lon":95},[99],{"name":100,"role":18,"phone":101,"phoneExt":10,"email":102},"Emma M Tillman, PhD, PharmD","(317) 274-2797","emtillma@iu.edu",{"facility":104,"status":27,"city":105,"state":106,"zip":107,"country":31,"countryCode":32,"cosmosGeoPoint":108,"geoPoint":112,"contacts":113},"Massachusetts General Hospital","Boston","Massachusetts","02114",{"type":34,"coordinates":109},[110,111],-71.05977,42.35843,{"lat":111,"lon":110},[114],{"name":115,"role":18,"phone":116,"phoneExt":10,"email":117},"Anna M Georgiopoulos, MD","617-724 -6300","AGEORGIOPOULOS@mgh.harvard.edu",{"facility":119,"status":27,"city":120,"state":121,"zip":122,"country":31,"countryCode":32,"cosmosGeoPoint":123,"geoPoint":127,"contacts":128},"University at Buffalo","Buffalo","New York","14215",{"type":34,"coordinates":124},[125,126],-78.87837,42.88645,{"lat":126,"lon":125},[129],{"name":130,"role":18,"phone":131,"phoneExt":10,"email":132},"Danielle M Goetz, MD","716-323-0110","dgoetz@upa.chob.edu",{"facility":134,"status":27,"city":135,"state":136,"zip":137,"country":31,"countryCode":32,"cosmosGeoPoint":138,"geoPoint":142,"contacts":143},"University of North Carolina School of Medicine","Chapel Hill","North Carolina","27599",{"type":34,"coordinates":139},[140,141],-79.05584,35.9132,{"lat":141,"lon":140},[144],{"name":145,"role":18,"phone":146,"phoneExt":10,"email":147},"Mary Beth Prieur, PhD","919-843-3209","mary_grimley@med.unc.edu",{"facility":149,"status":27,"city":150,"state":151,"zip":152,"country":31,"countryCode":32,"cosmosGeoPoint":153,"geoPoint":157,"contacts":158},"Cincinnati Children's Hospital Medical Center","Cincinnati","Ohio","45229",{"type":34,"coordinates":154},[155,156],-84.51439,39.12711,{"lat":156,"lon":155},[159],{"name":160,"role":18,"phone":161,"phoneExt":10,"email":162},"Stephanie Filigno, PhD","513-636-7793","stephanie.filigno@cchmc.org",{"facility":164,"status":165,"city":166,"state":167,"zip":168,"country":31,"countryCode":32,"cosmosGeoPoint":169,"geoPoint":173,"contacts":10},"Brown University Health","ACTIVE_NOT_RECRUITING","Providence","Rhode Island","02903",{"type":34,"coordinates":170},[171,172],-71.41283,41.82399,{"lat":172,"lon":171},{"facility":175,"status":27,"city":176,"state":177,"zip":178,"country":31,"countryCode":32,"cosmosGeoPoint":179,"geoPoint":183,"contacts":184},"UT Southwestern","Plano","Texas","75235",{"type":34,"coordinates":180},[181,182],-96.69889,33.01984,{"lat":182,"lon":181},[185],{"name":186,"role":18,"phone":187,"phoneExt":10,"email":188},"Meghna Sathe, MD","214-456-8000","meghna.sathe@utsouthwestern.edu",{"facility":190,"status":27,"city":191,"state":192,"zip":193,"country":31,"countryCode":32,"cosmosGeoPoint":194,"geoPoint":198,"contacts":199},"Children's Hospital of Richmond at Virginia Commonwealth University","Richmond","Virginia","23219",{"type":34,"coordinates":195},[196,197],-77.46026,37.55376,{"lat":197,"lon":196},[200],{"name":201,"role":18,"phone":202,"phoneExt":10,"email":203},"Michael S Schechter, MD, MPH","410- 550-7755","michael.schechter@vcuhealth.org",{"facility":205,"status":27,"city":206,"state":207,"zip":208,"country":31,"countryCode":32,"cosmosGeoPoint":209,"geoPoint":213,"contacts":214},"Seattle Children's Hospital","Seattle","Washington","98105",{"type":34,"coordinates":210},[211,212],-122.33207,47.60621,{"lat":212,"lon":211},[215],{"name":216,"role":18,"phone":217,"phoneExt":10,"email":218},"Freda Liu, PhD","206-987-3295","freda.liu@seattlechildrens.org",{"type":220,"investigatorFullName":17,"investigatorTitle":221,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal Investigator",[223,225],{"name":224,"class":6},"Cystic Fibrosis Foundation",{"name":226,"class":6},"Brown University","100596677","tides-20-prevalence-and-longitudinal-course-of-depression-anxiety-and-behavior-problems-in-children-with-cystic-fibrosis-under-12-years-of-age-100596677",false,"NCT07048574","TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age","TIDES 2","Inclusion Criteria:\n\n1. Child with a diagnosis of Cystic fibrosis (CF) actively followed by the CF care team at a participating site\n2. Child is age 18 months thru 11 years\n3. English and\u002For Spanish speaking\n4. Parent\u002Flegal guardian willing and able to give informed consent, and for minor participants ages 7 thru 11 years able to give assent.\n\nExclusion Criteria:\n\n* Unable or unwilling to participate in study procedures, or at Site PI discretion.","ALL","18 Months","11 Years",{"count":238,"type":239},600,"ESTIMATED","OBSERVATIONAL","This is a longitudinal, observational epidemiological study designed to estimate the prevalence of depression, anxiety, and behavior problems in children ages 18 months through 11 years with cystic fibrosis (CF).",[243],"Cystic Fibrosis (CF)",[245,246,247,248,249,250,251],"Cystic Fibrosis","Children","Mental health screening","Depression","Anxiety","CFTR modulators","Neuropsychiatric adverse events","2026-07-01",{"date":254,"type":255},"2026-07-06","ACTUAL",{"date":257,"type":255},"2025-06-02",{"date":259,"type":239},"2028-06-30",{"name":5,"class":6},13]