[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100404539":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":39,"responsibleParty":86,"collaborators":90,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":10,"eligibilityCriteria":98,"healthyVolunteers":95,"sex":99,"minAge":100,"maxAge":10,"enrollmentInfo":101,"targetDuration":10,"studyType":104,"phases":10,"briefSummary":105,"conditions":106,"keywords":109,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"First Affiliated Hospital, Sun Yat-Sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NPC group",null,"Patients pathologically diagnosed as NPC by agreement of 2 experienced pathologists who were blinded to the corresponding endoscopic assessment.",[13],"Diagnostic Test: rigid nasal endoscopes",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-NPC group","Patients pathologically diagnosed as non-NPC (including inflammatory hyperplasia, Atypical hyperplasia, Papilloma etc.) by agreement of 2 experienced pathologists who were blinded to the corresponding endoscopic assessment.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","rigid nasal endoscopes","The endoscope is introduced through the nasal passage to observe, in sequence, the posterior nostril, superior and posterior walls of the nasopharynx, torus tubarius, pharyngeal opening of the auditory tube, and Rosenmu¨ller recess. The imaging light mode is set to conventional WLI and subsequently switch to NBI during the procedure, and representative images are collected and preserve for further analysis. All lesions, detected by either WLI or NBI, are biopsied.",[9,15],[25],{"name":26,"affiliation":27,"role":28},"Weiping Wen, Ph.D","Otolaryngology Department, First Affiliated Hospital of Sun Yat-sen University","STUDY_DIRECTOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Yihui Wen, Ph.D","CONTACT","+86-13480200660","wenyihui@mail.sysu.edu.cn",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},"Rui He, M.D.","13096385286","herui27@mail2.sysu.edu.cn",[40,62,72],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"First Affiliated Hospital of Sun Yat-sen University","RECRUITING","Guangzhou","Guangdong","501180","China","CN",{"type":49,"coordinates":50},"Point",[51,52],113.25,23.11667,{"lat":52,"lon":51},[55,57,58,61],{"name":31,"role":32,"phone":56,"phoneExt":10,"email":34},"8613480200660",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},{"name":59,"role":60,"phone":10,"phoneExt":10,"email":10},"Yudong Long, M.D.","SUB_INVESTIGATOR",{"name":36,"role":60,"phone":10,"phoneExt":10,"email":10},{"facility":63,"status":42,"city":43,"state":44,"zip":64,"country":46,"countryCode":47,"cosmosGeoPoint":65,"geoPoint":67,"contacts":68},"Sun Yat-Sen University Cancer Center","510060",{"type":49,"coordinates":66},[51,52],{"lat":52,"lon":51},[69],{"name":70,"role":32,"phone":10,"phoneExt":10,"email":71},"Ying Sun, Ph.D","sunying@sysucc.org.cn",{"facility":73,"status":42,"city":74,"state":74,"zip":75,"country":46,"countryCode":47,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Kiang Wu Hospital","Macao","999078",{"type":49,"coordinates":77},[78,79],119.73136,31.44752,{"lat":79,"lon":78},[82],{"name":83,"role":32,"phone":84,"phoneExt":10,"email":85},"Weijian Hou, Ph.D","853-63001962","houwj75@sina.cn",{"type":87,"investigatorFullName":88,"investigatorTitle":89,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Weiping Wen","Vice President of First Affiliated Hospital, Sun Yat-Sen University; President of sixth Affiliated Hospital, Sun Yat-Sen University",[91],{"name":92,"class":6},"Sun Yat-sen University","100404539","to-develop-and-validate-a-nasoendoscopic-intelligent-diagnostic-system-for-nasopharyngeal-carcinoma-100404539",false,"NCT04547673","To Develop and Validate a Nasoendoscopic Intelligent Diagnostic System for Nasopharyngeal Carcinoma","Inclusion Criteria:\n\n* Older than 18 years of age\n\nExclusion Criteria:\n\n* Refuse to sign the informed consent statement\n* Patients who have contraindications, e.g. coagulation dysfunction, drug allergy.","ALL","18 Years",{"count":102,"type":103},1000,"ESTIMATED","OBSERVATIONAL","Nasopharyngeal carcinoma (NPC) occurs at a high frequency in southern China, northern Africa, and Alaska, with a reported incidence of 30 cases per 100 000 in Guangdong Province. Endoscopic examination and biopsy are the main methods used for detection and diagnosis of NPC. Early NPC patients achieve favourable prognoses after concurrent radiotherapy and chemotherapy in compassion with advanced NPC patients.\n\nHere, the investigators focused on the utility of artificial intelligence to detect early NPC, which based on white light imaging (WLI) and Narrow-band imaging (NBI) nasoendoscopic examination. Having access to this unique population provides an unprecedented opportunity to investigate the effect of intelligent system on diverse nasopharyngeal lesions detection and develop a novel Computer-Aided Diagnosis System.",[107,108],"Otolaryngological Disease","Artificial Intelligence",[110,111,112,113],"Nasopharyngeal Carcinoma","Endoscopy","Narrow-Band Imaging","White-Light Imaging","2024-02-16",{"date":116,"type":117},"2024-02-20","ACTUAL",{"date":119,"type":117},"2020-06-20",{"date":121,"type":103},"2026-12-31",{"name":5,"class":6},3]