[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649315":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":49,"collaborators":11,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":74,"whyStopped":11,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":64},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"transcutaneous auricular vagus nerve stimulation (taVNS)","EXPERIMENTAL",null,[13],"Device: transcutaneous auricular vagus nerve stimulation (taVNS)",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":11},"DEVICE","The participant will undergo 2-hour therapy sessions, 3 times per week, for 4 weeks for a total of 12 occupational therapy sessions with stimulation after the visit. Participants will receive 90 minutes of therapy per session. Stimulation will be delivered using a biphasic rectangular pulse, pulse width of 250 us, frequency of 25Hz, duty cycle of 30 seconds on \u002F 30 seconds off during active therapy. 1 second ramp up and ramp down will be used to improve comfort. Maximum total stimulation per session will not exceed 45 minutes.",[9],[20],{"name":21,"affiliation":5,"role":22},"Stuart M Fraser, MD","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":11,"email":27},"CONTACT","(713) 500-7142","Stuart.M.Fraser@uth.tmc.edu",{"name":29,"role":25,"phone":30,"phoneExt":11,"email":31},"Melika A Abrahams","(713) 500-6138","Melika.A.Abrahams@uth.tmc.edu",[33],{"facility":34,"status":11,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"The University of Texas Health Science Center at Houston","Houston","Texas","77030","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-95.36327,29.76328,{"lat":44,"lon":43},[47,48],{"name":21,"role":25,"phone":26,"phoneExt":11,"email":27},{"name":29,"role":25,"phone":30,"phoneExt":11,"email":31},{"type":22,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Stuart Mason Fraser","Assistant Professor","100649315","tolerability-of-transcutaneous-vagal-nerve-stimulation-100649315",false,"NCT07735234","Tolerability of Transcutaneous Vagal Nerve Stimulation","Tolerability of Transcutaneous Auricular Vagus Nerve Stimulation in Pediatric Stroke Survivors 1Tolerability of Transcutaneous Auricular Vagus Nerve Stimulation in Pediatric Stroke Survivors 1","TAPSS-1","Inclusion Criteria:\n\n* Childhood stroke survivor - either arterial ischemic stroke or intracerebral hemorrhage.\n* Stroke must be childhood onset, defined as occurring day 29 of life to 18 years of age (per the American Heart Association's definition of childhood stroke)\n* 6 months or greater from stroke onset\n* Arm impairment, defined as pediatric stroke outcome measure of 1 or greater of affected arm.\n* Affected arm Fugl-Meyer score of 60 or lower.\n* Able to participate in occupational therapy sessions.\n\nExclusion Criteria:\n\n* Craniectomy without replacement of bone flap. Patients who underwent craniectomy will need the bone flap reattached prior to participation.\n* Presence of cranial metal implants or implant device that could be affected by taVNS: cochlear implant, implanted brain stimulator, or programmable ventriculoperitoneal shunt.","ALL","13 Years","21 Years",{"count":64,"type":65},1,"ESTIMATED","INTERVENTIONAL",[68],"NA","The purpose of this study is to assess the feasibility and tolerability of transcutaneous auricular vagus nerve stimulation (taVNS) in childhood stroke survivors undergoing bi-manual occupational therapy.",[71],"Stroke",[73],"childhood stroke","NOT_YET_RECRUITING","2026-07-24",{"date":77,"type":78},"2026-07-29","ACTUAL",{"date":80,"type":65},"2026-07-30",{"date":82,"type":65},"2026-09-04",{"name":5,"class":6}]