[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647008":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":44,"locations":30,"responsibleParty":50,"collaborators":30,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":30,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":30,"maxAge":30,"enrollmentInfo":60,"targetDuration":30,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":74,"whyStopped":30,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":30},{"fullName":5,"class":6},"Universidade Federal de Pernambuco","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Active rTMS","EXPERIMENTAL","Participants will receive active repetitive transcranial magnetic stimulation (rTMS) alone, delivered according to the study protocol, without concurrent speech-language therapy.",[13],"Device: Active rTMS",{"label":15,"type":10,"description":16,"interventionNames":17},"Active rTMS + Speech-Language Therapy","Participants will receive active repetitive transcranial magnetic stimulation (rTMS) combined with speech-language therapy, administered according to the standardized intervention protocol.",[13,18],"Device: Speech-Language Therapy",{"label":20,"type":21,"description":22,"interventionNames":23},"Sham rTMS + Speech-Language Therapy","SHAM_COMPARATOR","Participants will receive sham repetitive transcranial magnetic stimulation (rTMS) combined with speech-language therapy. Sham stimulation will mimic active rTMS without delivering therapeutic magnetic stimulation.",[24,18],"Device: Sham rTMS",[26,31,35],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","Active repetitive transcranial magnetic stimulation (rTMS) delivered using a magnetic stimulator according to the study protocol.",[9,15],null,{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Sham rTMS","Sham repetitive transcranial magnetic stimulation (rTMS) delivered using a sham stimulation procedure designed to mimic active rTMS without delivering therapeutic magnetic stimulation.",[20],{"type":27,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Speech-Language Therapy","Standardized speech-language therapy focused on voice rehabilitation delivered by a licensed speech-language pathologist according to the study protocol.",[15,20],[40],{"name":41,"affiliation":42,"role":43},"Nathália Suellen Valeriano Cardoso Cardoso","UFPE - nathalia.suellen@ufpe.br","PRINCIPAL_INVESTIGATOR",[45],{"name":46,"role":47,"phone":48,"phoneExt":30,"email":49},"Katia K Monte-Silva","CONTACT","+55(81) 99503-2493","monte.silva@ufpe.br",{"type":43,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Kátia Monte-Silva","Professor","100647008","transcranial-magnetic-stimulation-in-laryngeal-dystonia-100647008",false,"NCT07683767","Transcranial Magnetic Stimulation in Laryngeal Dystonia","Inclusion Criteria:\n\n* Adults (≥18 years) of any sex with a confirmed diagnosis of laryngeal dystonia\n* Participants not undergoing botulinum toxin treatment at the time of the intervention\n* Ability to provide informed consent\n* Ability to complete all study assessments and intervention procedures\n\nExclusion Criteria:\n\n* Other forms of dystonia\n* Vocal fold lesions\n* Vocal fold paralysis\n* Contraindications to repetitive transcranial magnetic stimulation (rTMS)\n* Inability to complete study assessments or intervention procedures","ALL",{"count":61,"type":62},20,"ESTIMATED","INTERVENTIONAL",[65],"NA","This randomized clinical trial with a crossover design aims to investigate the effects of neuromodulation through repetitive transcranial magnetic stimulation (rTMS) applied to patients diagnosed with laryngeal dystonia. Participants will undergo three experimental conditions: (1) rTMS alone, (2) rTMS combined with speech-language therapy, and (3) sham rTMS combined with speech-language therapy. The order of the conditions will be randomized. Each phase of the protocol will consist of five consecutive sessions.\n\nOutcomes will include acoustic vocal quality parameters, perceptual-auditory voice assessment, self-ratings of vocal effort, smoothed cepstral peak prominence measures, and global perceived change following the intervention. It is expected that the study will contribute to a better understanding of the effects of the intervention on vocal outcomes, supporting the optimization and standardization of therapeutic protocols for laryngeal dystonia.",[68,69],"Laryngeal Dystonia","Spasmodic Dysphonia",[71,72,73],"Repetitive transcranial magnetic stimulation","Neuromodulation","Vocal quality","NOT_YET_RECRUITING","2026-06-27",{"date":77,"type":78},"2026-07-06","ACTUAL",{"date":80,"type":62},"2026-06",{"date":82,"type":62},"2027-02",{"name":5,"class":6}]