[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649509":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":45,"responsibleParty":71,"collaborators":73,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":26,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":26,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"University of Sao Paulo General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Contingency Management (CM) + Treatment as Usual (TAU)","EXPERIMENTAL","Participants receive standard outpatient treatment plus 12 weeks of remote contingency management delivered through the TRIS mobile application. Participants submit three breath alcohol concentration (BrAC) samples daily using a Bluetooth-enabled breathalyzer and receive escalating monetary incentives contingent on alcohol-negative breath samples.",[13],"Behavioral: Remote Contingency Management (CM)",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment as Usual (TAU)","ACTIVE_COMPARATOR","Participants receive standard outpatient treatment for Alcohol Use Disorder and use the TRIS mobile application to submit three daily breath alcohol concentration (BrAC) samples using a Bluetooth-enabled breathalyzer. No monetary incentives are provided for alcohol-negative breath samples.",[19],"Behavioral: Treatment as Usual (TAU)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Remote Contingency Management (CM)","Remote contingency management delivered through the TRIS mobile application. Participants submit three daily breath alcohol concentration (BrAC) samples using a Bluetooth-enabled BACtrack breathalyzer. Monetary incentives ranging from R$5.00 to R$15.00 per day are provided contingent on verified alcohol abstinence.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Standard outpatient treatment for Alcohol Use Disorder provided at the participating outpatient clinics. Participants also use the TRIS mobile application and a Bluetooth-enabled BACtrack breathalyzer for remote alcohol monitoring but do not receive contingency management incentives.",[15],[31],{"name":32,"affiliation":33,"role":34},"André Miguel, PhD","Washington State University","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Vinicius Soares, PhD","CONTACT","+55 19 99586-4530","viniciusnagy@gmail.com",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Aline Camargo Ramos, PhD","+55 11 95359-8039","aline.camargoramos@usp.br",[46],{"facility":47,"status":48,"city":49,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"IPER Research Center","RECRUITING","São Paulo","05021-001","Brazil","BR",{"type":54,"coordinates":55},"Point",[56,57],-46.63611,-23.5475,{"lat":57,"lon":56},[60,61,65,67,68,70],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},{"name":62,"role":38,"phone":63,"phoneExt":26,"email":64},"Thais Rocha, MSc","‪+55 11 99243-3412‬","thais.mentor@gmail.com",{"name":66,"role":34,"phone":26,"phoneExt":26,"email":26},"Paulo Menezes, PhD",{"name":32,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":37,"role":69,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"name":62,"role":69,"phone":26,"phoneExt":26,"email":26},{"type":72,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[74,76],{"name":75,"class":6},"University of Sao Paulo",{"name":77,"class":78},"Medical school of the University of São Paulo (FMUSP)","UNKNOWN","100649509","tris-contingency-management-app-for-alcohol-use-disorder-100649509",false,"NCT07735585","TRIS: Contingency Management App for Alcohol Use Disorder","Remote Treatment With Incentives for Sobriety (TRIS): A Randomized Controlled Trial of a Contingency Management App for Alcohol Use Disorder","Inclusion Criteria:\n\n* Able to read and speak Portuguese.\n* Provide signed informed consent.\n* Age 18 to 70 years.\n* Alcohol consumption within the past month.\n* Current diagnosis of Alcohol Use Disorder (AUD).\n* Seeking treatment for AUD at AME Vila Maria or Instituto Perdizes.\n* Breath alcohol concentration (BrAC) of 0.00 at the time of consent.\n* Own and be able to operate a smartphone with an active mobile service plan.\n* Smartphone compatible with the Bluetooth frequency required for the BACtrack breathalyzer.\n\nExclusion Criteria:\n\n* Crack cocaine use within the past 90 days.\n* Any seizure episode within the past 12 months.\n* Diagnosis of a psychotic disorder (DSM-5).\n* Suicide attempt within the past two years.\n* Any medical or psychiatric condition that may compromise safe participation, as determined by the study medical director.","ALL","18 Years","70 Years",{"count":90,"type":91},130,"ESTIMATED","INTERVENTIONAL",[94],"NA","Alcohol Use Disorder (AUD) is a major public health concern associated with substantial morbidity, mortality, and impaired social and occupational functioning. Contingency Management (CM) is an evidence-based behavioral intervention that provides incentives contingent on abstinence and has demonstrated effectiveness in the treatment of substance use disorders. This study will evaluate the efficacy of Tratamento Remoto com Incentivos à Sobriedade (TRIS), a Brazilian mobile health application that integrates a smartphone app with a Bluetooth-enabled breathalyzer (BACtrack) to deliver remote CM for AUD. Participants will be randomized to receive either standard outpatient treatment plus TRIS-based CM or standard outpatient treatment with remote alcohol monitoring only. The primary objective is to determine whether TRIS-based CM increases biochemically verified alcohol abstinence compared with standard outpatient treatment alone.",[97],"Alcohol Use Disorder (AUD)",[99,100,101],"Alcohol Use Disorder","Contingency Management","Sobriety","2026-07-27",{"date":104,"type":105},"2026-07-30","ACTUAL",{"date":107,"type":105},"2026-02-19",{"date":109,"type":91},"2027-12",{"name":5,"class":6},1]