[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645564":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":38,"locations":10,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":10,"overallStatus":66,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":10},{"fullName":5,"class":6},"Shanghai Pulmonary Hospital, Shanghai, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Two-Point SAPB Group",null,"Patients in this cohort receive ultrasound-guided two-point combined serratus anterior plane block for perioperative analgesia as part of routine clinical practice. A total of 30 mL local anesthetic is administered, with 15 mL injected deep to the serratus anterior muscle at the 3rd rib level and 15 mL at the 5th rib level.",[13],"Procedure: Two-Point Serratus Anterior Plane Block",{"label":15,"type":10,"description":16,"interventionNames":17},"Single-Point SAPB Group","Patients in this cohort receive ultrasound-guided single-point serratus anterior plane block for perioperative analgesia as part of routine clinical practice. A total of 30 mL local anesthetic is injected deep to the serratus anterior muscle at the 5th rib level in a single administration.",[18],"Procedure: Single-Point Serratus Anterior Plane Block",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Two-Point Serratus Anterior Plane Block","Ultrasound-guided fascial plane block for perioperative thoracic analgesia. Local anesthetic is deposited deep to the serratus anterior muscle at two separate rib levels, with equal volume split between the 3rd and 5th intercostal spaces.",[9],[26],"Two-Point SAPB; Double-Point Serratus Plane Block",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Single-Point Serratus Anterior Plane Block","Ultrasound-guided fascial plane block for perioperative thoracic analgesia. A single bolus of local anesthetic is deposited deep to the serratus anterior muscle at the 5th intercostal level.",[15],[32],"ingle-Point SAPB; Conventional Serratus Plane Block",[34],{"name":35,"affiliation":36,"role":37},"Shiyou Wei","Tongji University Affiliated Shanghai Pulmonary Hospital","PRINCIPAL_INVESTIGATOR",[39],{"name":35,"role":40,"phone":41,"phoneExt":10,"email":42},"CONTACT","15601680288","lovewishyou@tongji.edu.cn",{"type":44,"investigatorFullName":35,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Attending Physician","100645564","two-point-versus-single-point-serratus-anterior-plane-block-for-post-thoracoscopic-surgery-analgesia-100645564",false,"NCT07700823","Two-Point Versus Single-Point Serratus Anterior Plane Block for Post-Thoracoscopic Surgery Analgesia","Comparison of Ultrasound-Guided Two-Point Combined vs Single-Point Serratus Anterior Plane Block for Postoperative Analgesia in Thoracoscopic Surgery: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Aged 18 to 85 years at enrollment, regardless of sex\n* American Society of Anesthesiologists (ASA) physical status grade I to III\n* Scheduled for elective unilateral video-assisted thoracoscopic surgery\n* Planned to receive ultrasound-guided SAPB for routine perioperative analgesia\n* Able to understand study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Local infection or skin lesion at the block puncture site\n* Known hypersensitivity or allergy to amide local anesthetics\n* Preexisting sensory abnormality in the chest wall surgical area\n* Chronic opioid use for \\> 3 months, history of chronic pain syndrome, or history of opioid abuse\n* Severe coagulopathy (international normalized ratio \\> 1.5 or platelet count \\\u003C 80 × 10⁹\u002FL)\n* Cognitive impairment or inability to cooperate with postoperative pain assessment\n* Refusal to provide written informed consent","ALL","18 Years","85 Years",{"count":57,"type":58},88,"ESTIMATED","OBSERVATIONAL","Postoperative pain remains a common clinical challenge in patients undergoing video-assisted thoracoscopic surgery (VATS), impairing early recovery and increasing opioid consumption. The serratus anterior plane block (SAPB) is a widely used regional analgesic technique for thoracic surgery, but conventional single-point injection may have limited spread of local anesthetics, resulting in suboptimal analgesia in some patients. Preliminary anatomical evidence suggests that two-point combined SAPB may achieve wider dermatomal coverage and better analgesic efficacy.\n\nThis is a single-center, prospective observational cohort study conducted at Shanghai Pulmonary Hospital, China. A total of 88 adult patients scheduled for elective unilateral VATS will be consecutively enrolled and naturally assigned to either the two-point combined SAPB group (injection at the 3rd and 5th rib levels, total 30 ml local anesthetic) or the single-point SAPB group (injection at the 5th rib level, 30 ml local anesthetic) according to routine clinical practice.\n\nThe primary outcome is the verbal rating scale (VRS) pain score on coughing at 24 hours postoperatively. Secondary outcomes include resting and dynamic pain scores at multiple time points, cumulative opioid consumption at 24 and 48 hours, incidence of postoperative nausea and vomiting, block-related complications, length of hospital stay, and Quality of Recovery-15 (QoR-15) scores. This study aims to provide clinical evidence for optimizing perioperative analgesic strategies for thoracoscopic surgery.",[62,63,64,65],"Lung Cancer","Pain","Video-Assisted Thoracoscopic Surgery","Serratus Anterior Plane Block","NOT_YET_RECRUITING","2026-07-08",{"date":69,"type":70},"2026-07-14","ACTUAL",{"date":72,"type":58},"2026-08-01",{"date":74,"type":58},"2026-09-05",{"name":35,"class":6}]