[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658814":3},{"organization":4,"outcomesModule":7,"designInfo":31,"detailedDescription":37,"studyPopulation":30,"armGroups":38,"interventions":51,"overallOfficials":30,"centralContacts":61,"locations":67,"responsibleParty":83,"collaborators":30,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":30,"eligibilityCriteria":93,"healthyVolunteers":89,"sex":94,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":30,"studyType":100,"phases":101,"briefSummary":103,"conditions":104,"keywords":30,"overallStatus":70,"whyStopped":30,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"National Cancer Institute, Egypt","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":30},[9],{"measure":10,"description":11,"timeFrame":12},"Degree of pain","Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents \"no pain\" while 10 represents \"the worst pain imaginable\").","24 hours postoperatively",[14,18,21,24,27],{"measure":15,"description":16,"timeFrame":17},"Total fentanyl consumption","When elevation of Heart rate (HR) or mean arterial blood pressure (MAP) ≥ 20% of the baseline will be treated by fentanyl 0.5 μg \u002F kg.","Intraoperatively",{"measure":19,"description":20,"timeFrame":12},"Total opioid consumption","The patients will be observed in the postoperative care unit for 2 h, and rescue analgesia will be provided in the form of intravenous morphine 3 mg with maximum dose of 0.1 mg\u002Fkg\u002Fdose (max 0.3 mg\u002Fkg\u002Fday) boluses if the pain score \\>3. The total amount of morphine given in 24 h will be recorded for every patient.",{"measure":22,"description":23,"timeFrame":12},"Mean arterial pressure","Mean arterial pressure will be recorded before injection of the local anesthetics to be defined as a baseline reading and after injection then will be recorded immediately before and after surgical incision, at 30 min intervals intraoperatively, and immediately postoperative and at 2, 4, 6, 12 and 24 h postoperatively.",{"measure":25,"description":26,"timeFrame":12},"Heart rate","Heart rate will be recorded before injection of the local anesthetics to be defined as a baseline reading and after injection then will be recorded immediately before and after surgical incision, at 30 min intervals intraoperatively, and immediately postoperative and at 2, 4, 6, 12 and 24 h postoperatively.",{"measure":28,"description":29,"timeFrame":12},"Incidence of complications","Incidence of complications such as hemodynamic instability, nausea, vomiting, failed block, unintentional intravascular injection of local anesthesia and local anesthetic toxicity will be recorded",null,{"allocation":32,"interventionModel":33,"interventionModelDescription":30,"primaryPurpose":34,"observationalModel":30,"timePerspective":30,"maskingInfo":35},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":36,"maskingDescription":30,"whoMasked":30},"NONE","Inguinal lymph node dissection is the surgical removal of lymph nodes from your groin (where your legs meet your lower abdomen). Inguinal lymph node dissection is used to see if cancer has spread from certain areas (usually your penis, vulva, anus or the skin on your legs or torso), remove lymph nodes that may be cancerous or have a high chance of becoming cancerous, reduce the risk that cancer will come back in the future and help providers understand the options for treating your cancer and help you know what to expect.\n\nTransversalis fascia plane block (TFPB) used in patients undergoing various surgeries like iliac crest bone harvesting, appendicectomy, cecostomy and inguinal hernia repair, often in combination with TAP block.\n\nThe initial description of TFPB was with patients in the supine position, with a linear array or curvilinear probe placed between the iliac crest and the costal margin. The external oblique, internal oblique and transversus abdominis muscles and the transversus aponeurosis are identified.",[39,45],{"label":40,"type":41,"description":42,"interventionNames":43},"Group 1","SHAM_COMPARATOR","Patients will receive a sham block was performed using an equivalent volume of normal saline 0.9%.",[44],"Drug: Saline 0.9%",{"label":46,"type":47,"description":48,"interventionNames":49},"Group 2","EXPERIMENTAL","Patients will receive ultrasound guided transversalis fascia plane block.",[50],"Drug: Transversalis fascia plane block",[52,56],{"type":53,"name":54,"description":42,"armGroupLabels":55,"otherNames":30},"DRUG","Saline 0.9%",[40],{"type":53,"name":57,"description":48,"armGroupLabels":58,"otherNames":59},"Transversalis fascia plane block",[46],[60],"20 ml of bupivacaine 0.25%",[62],{"name":63,"role":64,"phone":65,"phoneExt":30,"email":66},"Ahmed S Abdelgalil, MD","CONTACT","00201098426689","ahmed.salah@nci.cu.edu.eg",[68],{"facility":69,"status":70,"city":71,"state":30,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":81},"Cairo University","RECRUITING","Cairo","12613","Egypt","EG",{"type":76,"coordinates":77},"Point",[78,79],31.24967,30.06263,{"lat":79,"lon":78},[82],{"name":63,"role":64,"phone":65,"phoneExt":30,"email":66},{"type":84,"investigatorFullName":85,"investigatorTitle":86,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Ahmed Salah Ahmed Abd Elgalil","Associate Professor of Anaesthesia and Pain Medicine National Cancer, Cairo University.","100658814","ultrasound-guided--chemical-rectus-sheath-block-for-chronic-pain-after-abdominal-midline-incision-in-cancer-surgeries-100658814",false,"NCT07855380","Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries","Evaluation of Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries: A Prospective Randomized Controlled Study","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) class I and II.\n* Age ≥ 18 and ≤ 65 Years.\n* Cancer patients for inguinal lymph node dissection.\n* Body mass index (BMI): \\> 20 kg\u002Fm2 and \\\u003C 40 kg\u002Fm2.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Local infection at the puncture site.\n* Coagulopathies with platelet count below 50,000 or an INR\\>1.6.\n* Unstable cardiovascular disease.\n* History of psychiatric and cognitive disorders.\n* Patients allergic to medication used.","ALL","18 Years","65 Years",{"count":98,"type":99},90,"ESTIMATED","INTERVENTIONAL",[102],"NA","The aim of this study is to evaluate peri-operative analgesia efficacy of ultrasound guided transversalis fascia plane block in cancer patients undergoing inguinal lymph node dissection",[105,106,107,108],"Chemical Rectus Sheath Block","Chronic Pain","Abdominal Midline Incision","Cancer Surgeries","2026-09-28",{"date":111,"type":112},"2026-10-02","ACTUAL",{"date":114,"type":112},"2026-05-01",{"date":116,"type":99},"2026-12-01",{"name":5,"class":6},1]