[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646960":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Ohio State University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Pregnant Women undergoing Cesarean Delivery",null,[12],"Device: ClearSight",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","ClearSight","The ClearSight system provides continuous blood pressure and advanced hemodynamic parameters from a noninvasive finger cuff sensor. Therefore, placing both cuff sensors in different arms will ensure no interference with the ClearSight readings due to the conventional blood pressure cuff inflation.",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Ling-Qun Hu, MD","CONTACT","6142936302","LingQun.Hu@osumc.edu",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Alberto Uribe, MD","6142933559","Alberto.uribe@osumc.edu",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"The Ohio State University","RECRUITING","Columbus","Ohio","43210","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-82.99879,39.96118,{"lat":42,"lon":41},[45,47],{"name":26,"role":22,"phone":27,"phoneExt":10,"email":46},"alberto.uribe@osumc.edu",{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ling-Qun Hu","Assistant Professor","100646960","upper-vs-lower-extremity-bp-in-spinal-cesarean-using-clearsight-100646960",false,"NCT07685730","Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight","Comparative Analysis of the Predictive Performance of Noninvasive Beat-by-Beat Blood Pressure and Flow Measurements at the Lower Extremity Versus the Upper Extremity for Neonatal Outcomes Under Spinal Anesthesia for Elective Cesarean Delivery","Inclusion Criteria:\n\n* Age ≥ 18 years old\n* Singleton pregnancy\n* Gestational age ≥ 37 weeks\n* Women undergoing CD under SAB or Combined Spinal-Epidural (CSE) electively.\n* Ability to consent in English and in Spanish language\n\nExclusion Criteria:\n\n* CD under or converted to general anesthesia\n* CD under epidural anesthesia or converted to epidural anesthesia\n* Diabetes Mellitus (DM)\u002FGestational Diabetes Mellitus (GDM)\n* Evidence of unstable cardiac disease other than HDP (including chronic hypertension, gestational hypertension, preeclampsia-eclampsia, and chronic hypertension with superimposed preeclampsia) judged by the investigator to have any impact on BP will make the subject unsuitable for participation in the study\n* Documented fetal anomaly\u002F congenital malformations and genetic syndromes\n* Intrauterine growth retardation\n* Unable to consent in English\u002FSpanish.\n* Prisoners",true,"FEMALE","18 Years",{"count":63,"type":64},327,"ESTIMATED","OBSERVATIONAL","This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia. It compares whether continuous noninvasive hemodynamic measurements from the lower extremity (toe) better predict neonatal outcomes than upper extremity (arm\u002Ffinger) measurements during spinal-induced hypotension.\n\nParticipants receive standard spinal anesthesia and routine blood pressure management, with additional monitoring using the ClearSight™ system at both upper and lower extremities from before spinal anesthesia through delivery.\n\nThe primary outcome is a composite of neonatal outcomes (APGAR scores, need for respiratory support, cord gases, and NICU admission). Secondary outcomes include maternal side effects and comfort.\n\nOverall, the study evaluates whether lower-extremity hemodynamic monitoring improves detection of clinically relevant hypotension and prediction of neonatal outcomes compared to traditional arm measurements.",[68,69,70],"Anesthesia","Pregnancy Related","Blockades Neuromuscular","2026-06-29",{"date":73,"type":74},"2026-07-06","ACTUAL",{"date":76,"type":74},"2025-02-06",{"date":78,"type":64},"2029-08-06",{"name":5,"class":6},1]