[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649025":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":41,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":61,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cardiac Surgery Cohort",null,"Adult patients undergoing cardiac surgery at Nanjing First Hospital who will receive perioperative vascular aging assessment and postoperative renal function monitoring according to the study protocol. No treatment or perioperative management strategy will be assigned by the study protocol.",[13],"Other: Multidimensional Vascular Aging Assessment",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Multidimensional Vascular Aging Assessment","Perioperative assessment of vascular aging-related indicators, including noninvasive vascular assessments, hemodynamic measurements, and relevant clinical and laboratory variables. The assessment is observational and will not determine the treatment, surgical procedure, or perioperative management assigned to participants.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"F Hu","CONTACT","+8615162614385","feifanhu0722@foxmail.com",[26],{"facility":5,"status":10,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Nanjing","Jiangsu","210006","China","CN",{"type":33,"coordinates":34},"Point",[35,36],118.77778,32.06167,{"lat":36,"lon":35},[39],{"name":40,"role":22,"phone":23,"phoneExt":10,"email":24},"Feifan Hu",{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100649025","vascular-aging-and-acute-kidney-injury-after-cardiac-surgery-100649025",false,"NCT07727772","Vascular Aging and Acute Kidney Injury After Cardiac Surgery","Multidimensional Assessment of Vascular Aging and Its Association With Postoperative Acute Kidney Injury in Patients Undergoing Cardiac Surgery","Inclusion Criteria:\n\n* Adult patients aged 18 years or older.\n* Patients scheduled to undergo cardiac surgery at Nanjing First Hospital, Nanjing Medical University.\n* Patients who are able to provide written informed consent.\n* Patients who are expected to undergo perioperative vascular aging assessment and postoperative renal function monitoring according to the study protocol.\n\nExclusion Criteria:\n\n* Patients younger than 18 years.\n* Patients with preoperative end-stage renal disease or maintenance dialysis.\n* Patients who are unable to complete the study-specified vascular aging assessment.\n* Patients who decline participation or withdraw informed consent.","ALL","18 Years",{"count":53,"type":54},472,"ESTIMATED","OBSERVATIONAL","This prospective observational cohort study will enroll adult patients undergoing cardiac surgery at Nanjing First Hospital, Nanjing Medical University. The study will evaluate multidimensional vascular aging markers before surgery and assess their association with postoperative acute kidney injury within 7 days after surgery. No intervention will be assigned by the study protocol, and all perioperative management will follow routine clinical practice.",[58,59,60],"Acute Kidney Injury Cardiac Surgery","Postoperative Complications","Vascular Aging",[62,63,64],"vascular aging","acute kidney injury","postoperative complications","NOT_YET_RECRUITING","2026-07-22",{"date":68,"type":69},"2026-07-27","ACTUAL",{"date":71,"type":54},"2026-07-01",{"date":73,"type":54},"2027-12-28",{"name":5,"class":6},1]