[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652926":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":26,"locations":35,"responsibleParty":49,"collaborators":52,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":26,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":82,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Indiana University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: VICA","EXPERIMENTAL","Access to the VICA AI-powered avatar platform for 3 months; caregivers encouraged to engage 3x\u002Fweek for \\~20 minutes per session. VICA delivers education, resource information, and symptom-monitoring (HABC-Monitor) grounded in the ABC collaborative dementia care model via a retrieval-augmented generation (RAG) system.",[13],"Device: VICA - Virtual Informal Care Assistant",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Comparator: Attention Control","ACTIVE_COMPARATOR","Access to Dementia Guide Expert, an existing free, education-only BPSD mobile app (ENGAGE-IL initiative, University of Illinois at Chicago), used on the same 3x\u002Fweek, \\~20 minute schedule for 3 months. No interactive coaching, assessment, or personalized response.",[19],"Device: Education only BPSD mobile app",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","VICA - Virtual Informal Care Assistant","An AI-powered avatar delivering conversational, speech-to-speech and text-based education, resource information, and symptom-monitoring support to informal caregivers of patients with Alzheimer's disease and related dementias (ADRD), grounded in the ABC collaborative dementia care model via a retrieval-augmented generation system.",[9],null,{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Education only BPSD mobile app",[15],[31],{"name":32,"affiliation":33,"role":34},"Malaz Boustani, MD, MPH","Indiana University School of Medicine, Center for Health Innovation and Implementation Science","PRINCIPAL_INVESTIGATOR",[36],{"facility":37,"status":26,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":26},"Eskanazi Health","Indianapolis","Indiana","46202","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-86.15804,39.76838,{"lat":47,"lon":46},{"type":34,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"MALAZ BOUSTANI","Professor of Medicine",[53],{"name":54,"class":6},"University of Notre Dame","100652926","vica-a-virtual-care-assistant-for-dementia-caregivers-100652926",false,"NCT07779785","VICA: A Virtual Care Assistant for Dementia Caregivers","Virtual Informal Care Assistant for Alzheimer'S-related Dementia (VICA): A Pilot Randomized Controlled Trial","VICA","Inclusion Criteria: Patient\n\n* Age ≥ 65 years\n* Community-dwelling\n* Diagnosed with ADRD\n* Clinical notes indicate behavioral and psychological symptoms of dementia (BPSD) Inclusion Criteria: Informal Caregiver\n* Age ≥ 21 years\n* Self-identified informal caregiver of a community-dwelling patient diagnosed with ADRD\n* Provides ≥ 10 hours\u002Fweek of care to the patient with ADRD\n* Regular access to a computer and\u002For smart device with internet\n* English-literate; assessed as \"adequate\" on the Single Item Literacy Screener\n\nExclusion Criteria: Patient\n\n* Life expectancy less than 6 months\n\nExclusion Criteria: Informal Caregiver\n\n* Clinician-reported cognitive impairment\n* Clinician-reported severe mental illness or substance use disorder\n* Clinician-reported life expectancy of less than 6 months\n* Unable to provide informed consent","ALL","21 Years",{"count":66,"type":67},120,"ESTIMATED","INTERVENTIONAL",[70],"NA","This pilot randomized controlled trial evaluates the feasibility and preliminary efficacy of VICA, an AI-powered virtual care assistant that delivers evidence-based education, symptom monitoring, and coaching to informal caregivers of people living with Alzheimer's disease and related dementias (ADRD). Sixty caregiver-patient dyads will be randomized 1:1 to VICA or an attention-control education app (Dementia Guide Expert) for 3 months. The study will assess recruitment, VICA acceptance\u002Fusability, and engagement (Aim 1), and estimate effect sizes for reducing patient behavioral and psychological symptoms of dementia (BPSD) and caregiver distress (Aim 2).",[73,74],"Alzheimer Dementia (AD)","Caregiver Burden of People With Dementia",[76,77,78,79,80,81],"behavioral and psychological symptoms of dementia","conversational AI","avatar","informal caregiver","digital therapeutic","ABC collaborative dementia care model","NOT_YET_RECRUITING","2026-08-18",{"date":85,"type":86},"2026-08-21","ACTUAL",{"date":88,"type":67},"2026-08-17",{"date":90,"type":67},"2027-05-30",{"name":5,"class":6},1]