[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649723":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":43,"locations":49,"responsibleParty":66,"collaborators":10,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":10,"studyType":83,"phases":10,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Sichuan Academy of Medical Sciences","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Dual focus + Dual focus group",null,"Patients undergoing bilateral implantation of dual-focus intraocular lenses in both eyes",[13],"Device: Bilateral Bifocal IOL Implantation",{"label":15,"type":10,"description":16,"interventionNames":17},"Dual focus + EDOF group","Patients undergoing bilateral implantation of a dual-focus intraocular lens in one eye and an Extended Depth of Focus (EDOF) lens in the contralateral eye",[18],"Device: Bifocal and EDOF IOL Mix-and-Match Implantation",{"label":20,"type":10,"description":21,"interventionNames":22},"Dual focus + Single focus group","Patients undergoing bilateral implantation of a dual-focus intraocular lens in one eye and a monofocal intraocular lens in the contralateral eye.",[23],"Device: Bifocal and Monofocal IOL Mix-and-Match Implantation",[25,30,34],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"DEVICE","Bilateral Bifocal IOL Implantation","Bilateral phacoemulsification with bifocal intraocular lens implantation in both eyes.",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"Bifocal and EDOF IOL Mix-and-Match Implantation","Bilateral phacoemulsification with bifocal intraocular lens implantation in one eye and EDOF intraocular lens implantation in the contralateral eye.",[15],{"type":26,"name":35,"description":36,"armGroupLabels":37,"otherNames":10},"Bifocal and Monofocal IOL Mix-and-Match Implantation","Bilateral phacoemulsification with bifocal intraocular lens implantation in one eye and monofocal intraocular lens implantation in the contralateral eye.",[20],[39],{"name":40,"affiliation":41,"role":42},"Chao Qu","School of Medicine, University of Electronic Science and Technology of China","PRINCIPAL_INVESTIGATOR",[44],{"name":45,"role":46,"phone":47,"phoneExt":10,"email":48},"Xiangjun Fu, Ph.D.","CONTACT","+86-28-87393999","243981469@qq.com",[50],{"facility":51,"status":52,"city":53,"state":10,"zip":10,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Sichuan Provincial People's Hospital","RECRUITING","Chengdu","China","CN",{"type":57,"coordinates":58},"Point",[59,60],104.06667,30.66667,{"lat":60,"lon":59},[63],{"name":64,"role":46,"phone":47,"phoneExt":10,"email":65},"Xiang Yang,, M.D","xiangyangttt@126.com",{"type":42,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"ChaoQu","Professor, Department of Ophthalmology","100649723","visual-adaptation-and-quality-of-life-after-different-iol-implantation-strategies-100649723",false,"NCT07740590","Visual Adaptation and Quality of Life After Different IOL Implantation Strategies","Evaluation of Visual Adaptation and Optical Performance in Patients With Bilateral Multifocal or Mix-and-Match Intraocular Lens Implantation: A Longitudinal Observational Study","MMAQ-IOL","Inclusion Criteria:\n\n* Age 18 years or older with age-related cataract requiring bilateral phacoemulsification and intraocular lens (IOL) implantation\n* Corneal astigmatism less than 0.75 D\n* Good general health and willing to complete all postoperative follow-up visits\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Previous ocular surgery or ocular trauma\n* Coexisting ocular diseases affecting visual potential, such as corneal opacity, glaucoma, macular degeneration, or diabetic retinopathy\n* Intraoperative or postoperative complications (e.g., posterior capsule rupture)\n* Systemic diseases that may interfere with visual outcomes or follow-up compliance","ALL","18 Years","100 Years",{"count":81,"type":82},264,"ESTIMATED","OBSERVATIONAL","This longitudinal observational study aims to evaluate long-term visual adaptation trajectories, optical quality, and patient-reported outcomes in age-related cataract patients following bilateral implantation of multifocal or mix-and-match intraocular lenses (IOLs). Patients will be followed up longitudinally after surgery to systematically assess visual performance and quality of life.",[86,87],"Cataract","Aphakia - Lens Capsule Present",[89,90,91,92,93],"Intraocular Lenses","Multifocal Intraocular Lenses","Neuroadaptation","Visual Performance","Quality of Life","2026-07-29",{"date":96,"type":97},"2026-07-31","ACTUAL",{"date":99,"type":97},"2025-03-01",{"date":101,"type":82},"2027-12-31",{"name":5,"class":6},1]