[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649364":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":18,"collaborators":10,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":27,"acronym":28,"eligibilityCriteria":29,"healthyVolunteers":24,"sex":30,"minAge":31,"maxAge":10,"enrollmentInfo":32,"targetDuration":10,"studyType":35,"phases":10,"briefSummary":36,"conditions":37,"keywords":44,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":54,"leadSponsor":56,"locationsCount":10},{"fullName":5,"class":6},"Sinai University","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Vitamin D Deficient Group",null,"Adults with bronchial asthma and serum 25-hydroxyvitamin D concentrations below 20 ng\u002FmL.",{"label":13,"type":10,"description":14,"interventionNames":10},"Vitamin D Insufficient Group","Adults with bronchial asthma and serum 25-hydroxyvitamin D concentrations between 20 and 30 ng\u002FmL.",{"label":16,"type":10,"description":17,"interventionNames":10},"Vitamin D Sufficient Group","Adults with bronchial asthma and serum 25-hydroxyvitamin D concentrations above 30 ng\u002FmL.",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Amany Gomaa Atiaa","lecturer","100649364","vitamin-d-status-and-asthma-control-pulmonary-function-and-oxidative-stress-in-adults-with-bronchial-asthma-100649364",false,"NCT07733635","Vitamin D Status and Asthma Control, Pulmonary Function, and Oxidative Stress in Adults With Bronchial Asthma","Association Between Serum Vitamin D Status, Asthma Control, Pulmonary Function, and Oxidative Stress Biomarkers in Egyptian Adults With Bronchial Asthma: A Cross-Sectional Study","VD-ASTHMA","Inclusion Criteria\n\n* Age ≥ 18 years.\n* Confirmed diagnosis of bronchial asthma.\n* Clinically stable at the time of assessment.\n* Availability of spirometry results.\n* Availability of laboratory investigations including serum 25(OH)D and oxidative stress biomarkers.\n\nExclusion Criteria\n\n* Other chronic pulmonary diseases.\n* Active respiratory infection.\n* Malignancy.\n* Significant renal or hepatic disease.\n* Pregnancy.\n* Current vitamin D supplementation.\n* Other conditions known to markedly influence oxidative stress status.","ALL","18 Years",{"count":33,"type":34},134,"ESTIMATED","OBSERVATIONAL","Asthma is a chronic inflammatory airway disease associated with variable airflow limitation and persistent respiratory symptoms. Vitamin D has been proposed as a potential biomarker related to immune regulation, asthma control, pulmonary function, and oxidative stress balance.\n\nThis prospective cross-sectional observational study aims to investigate the association between serum 25-hydroxyvitamin D \\[25(OH)D\\] concentrations, asthma control, pulmonary function parameters, and erythrocyte oxidative stress biomarkers among Egyptian adults with bronchial asthma.\n\nA total of 200 adult asthma patients will be recruited from Abbassia Chest Hospital, Cairo, Egypt. Participants will undergo clinical assessment, Asthma Control Test (ACT), post-bronchodilator spirometry, serum vitamin D measurement, and oxidative stress biomarker assessment including malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx), and reduced glutathione (GSH).\n\nParticipants will be categorized according to serum 25(OH)D concentrations into vitamin D deficient, insufficient, and sufficient groups.\n\nNo intervention or treatment assignment will be performed.\n\n5\\. Detailed Description",[38,39,40,41,42,43],"Bronchial Asthma","Vitamin D Deficiency","Pulmonary Function Impairment","Oxidative Stress","Asthma","Antioxidant",[39,38,45,46,41,47],"Pulmonary Function","Spirometry","Malondialdehyde","NOT_YET_RECRUITING","2026-07-26",{"date":51,"type":52},"2026-07-29","ACTUAL",{"date":49,"type":34},{"date":55,"type":34},"2027-02-25",{"name":5,"class":6}]