[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649116":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":22,"centralContacts":29,"locations":39,"responsibleParty":66,"collaborators":22,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":22,"enrollmentInfo":80,"targetDuration":22,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":99,"whyStopped":22,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Federal University of Rio Grande do Sul","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Vivifrail - 2 sessions\u002Fweek (G1)","EXPERIMENTAL","Home-based Vivifrail multicomponent exercise program performed at least twice a week for 24 weeks, individualized by functional profile (SPPB and Vivifrail passport).",[13],"Behavioral: Vivifrail multicomponent exercise program",{"label":15,"type":10,"description":16,"interventionNames":17},"Vivifrail - 3 sessions\u002Fweek (G2)","Home-based Vivifrail multicomponent exercise program performed at least three times a week for 24 weeks, individualized by functional profile.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Control (GC)","NO_INTERVENTION","Participants maintain usual activities without a structured exercise program during the 24-week period.",null,[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":22},"BEHAVIORAL","Vivifrail multicomponent exercise program","Individualized multicomponent home-based training (strength\u002Fpower, balance, gait, and flexibility) prescribed according to the participant's Vivifrail functional profile.",[9,15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":22,"email":34},"ALESSANDRA Silva QUADROS","CONTACT","+5551991020557","quadros.ale@gmail.com",{"name":36,"role":32,"phone":37,"phoneExt":22,"email":38},"Caroline Pietta Dias, PhD","+55 51 84484400","carolpieta@yahoo.com.br",[40,57],{"facility":41,"status":22,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Hospital de Clínicas de Porto Alegre (HCPA) - Geriatrics outpatient clinic","Porto Alegre","Rio Grande do Sul","90035-903","Brazil","BR",{"type":48,"coordinates":49},"Point",[50,51],-51.23019,-30.03283,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":56,"phoneExt":22,"email":34},"ALESSANDRA QUADROS","5199466032",{"facility":58,"status":22,"city":42,"state":43,"zip":59,"country":45,"countryCode":46,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"Escola de Educação Física, Fisioterapia e Dança (ESEFID\u002FUFRGS) - and participants' homes","90690-200",{"type":48,"coordinates":61},[50,51],{"lat":51,"lon":50},[64],{"name":55,"role":32,"phone":65,"phoneExt":22,"email":34},"51991020557",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"PRINCIPAL_INVESTIGATOR","Alessandra Quadros","Doctoral Candidate and Principal Investigator","100649116","vivifrail-exercise-program-in-nonagenarians-effects-on-function-muscle-and-cognition-100649116",false,"NCT07731529","Vivifrail Exercise Program in Nonagenarians: Effects on Function, Muscle, and Cognition","Effects of a Multicomponent Exercise Program Based on the Vivifrail Protocol on Functional Capacity, Muscle Morphology, and Cognition in Nonagenarians: A Randomized Clinical Trial","Vivifrail","Inclusion Criteria:\n\n* Aged 90 years or older\n* Living in the community (own or family home)\n* Able to walk independently or with a walking aid (cane or walker), without third-party assistance\n* Minimum cognitive capacity to understand and perform the exercises (MMSE, education-adjusted cutoffs)\n* Adequate home conditions to perform the program\n* Availability of a family member or caregiver to support the sessions\n* Signed informed consent (with legal guardian assistance when needed)\n\nExclusion Criteria:\n\n* \\- Total inability to walk or permanent bedridden condition\n* Severe cognitive impairment preventing safe understanding and execution of exercises\n* Severe orthopedic, neurological, or rheumatological conditions preventing exercise\n* Concurrent participation in another structured exercise program\n* Anticipated unavailability (relocation, planned hospitalization, or institutionalization) during the intervention\n* Refusal to sign informed consent or absence of a legal guardian when required","ALL","90 Years",{"count":81,"type":82},54,"ESTIMATED","INTERVENTIONAL",[85],"NA","This randomized clinical trial investigates the effects of a home-based multicomponent exercise program (Vivifrail) on physical function, muscle morphology, and cognition in community-dwelling adults aged 90 years and older. Participants are randomized into three groups: Vivifrail at least twice a week, Vivifrail at least three times a week, or a control group. Outcomes are assessed at baseline, 12 weeks, and 24 weeks. The primary outcome is physical function measured by the Short Physical Performance Battery (SPPB).",[88,89,90],"Frailty","Aging","Cognitive Decline",[76,92,93,94,95,96,97,98],"Multicomponent exercise","Nonagenarians","Physical function","Short Physical Performance Battery","Muscle quality","Muscle morphology","Home-based exercise","NOT_YET_RECRUITING","2026-07-24",{"date":102,"type":103},"2026-07-28","ACTUAL",{"date":105,"type":82},"2026-07",{"date":107,"type":82},"2027-09",{"name":5,"class":6},2]