[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650146":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":89,"collaborators":92,"id":96,"slug":97,"hasResults":98,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":11,"eligibilityCriteria":102,"healthyVolunteers":98,"sex":103,"minAge":104,"maxAge":11,"enrollmentInfo":105,"targetDuration":11,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":11,"overallStatus":114,"whyStopped":11,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual World-based Cardiac Rehabilitation","EXPERIMENTAL",null,[13],"Other: Virtual Cardiac Rehabilitation",{"label":15,"type":16,"description":11,"interventionNames":17},"Control Arm","ACTIVE_COMPARATOR",[18],"Other: In-Person Cardiac Rehabilitation",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Virtual Cardiac Rehabilitation","* Weekly Virtual Cardiac Rehabilitation Session\n* Virtual Nurse Coaching Visit (frequency: weekly)\n* Virtual Exercise Physiologist Visit (frequency: weekly)\n* Self-Directed Exercise: 3 sessions per week",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"In-Person Cardiac Rehabilitation","Participants will attend three in-person cardiac rehabilitation sessions per week, each including:\n\n* Supervised exercise under the guidance of an Exercise Physiologist\n* Educational components related to cardiac health and lifestyle",[15],[29],{"name":30,"affiliation":5,"role":31},"LaPrincess Brewer, MD, MPH","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":11,"email":37},"Ashton Krogman","CONTACT","507-266-2087","krogman.ashton@mayo.edu",{"name":39,"role":35,"phone":40,"phoneExt":11,"email":11},"Lainey Moen","507-266-7062",[42,62,71],{"facility":43,"status":11,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"University of California","Irvine","California","92697","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-117.82311,33.66946,{"lat":53,"lon":52},[56,58,60],{"name":57,"role":35,"phone":11,"phoneExt":11,"email":11},"Ashwini Erande",{"name":59,"role":31,"phone":11,"phoneExt":11,"email":11},"Nathan Wong, PhD",{"name":61,"role":31,"phone":11,"phoneExt":11,"email":11},"Shaista Malik, MD, PhD",{"facility":5,"status":11,"city":63,"state":64,"zip":65,"country":47,"countryCode":48,"cosmosGeoPoint":66,"geoPoint":70,"contacts":11},"Rochester","Minnesota","55905",{"type":50,"coordinates":67},[68,69],-92.4699,44.02163,{"lat":69,"lon":68},{"facility":72,"status":11,"city":73,"state":74,"zip":75,"country":47,"countryCode":48,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"University of Mississippi Medical Center","Jackson","Mississippi","39216",{"type":50,"coordinates":77},[78,79],-90.18481,32.29876,{"lat":79,"lon":78},[82,85,87],{"name":83,"role":35,"phone":11,"phoneExt":11,"email":84},"Memrie Cochran","mcochran1@umc.edu",{"name":86,"role":31,"phone":11,"phoneExt":11,"email":11},"Michael Hall, MD",{"name":88,"role":31,"phone":11,"phoneExt":11,"email":11},"Donald Clark, MD",{"type":31,"investigatorFullName":90,"investigatorTitle":91,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"LaPrincess C. Brewer","Principal Investigator",[93],{"name":94,"class":95},"National Library of Medicine (NLM)","NIH","100650146","vwcr-to-improve-cardiovascular-health-and-outcomes-among-cardiac-patients-a-multicenter-randomized-clinical-trial-protocol-destination-cardiac-rehab-study-100650146",false,"NCT07745894","VWCR to Improve Cardiovascular Health and Outcomes Among Cardiac Patients: A Multicenter Randomized Clinical Trial Protocol (Destination Cardiac Rehab Study)","Virtual World-based Cardiac Rehabilitation to Improve Cardiovascular Health and Outcomes Among Cardiac Patients: A Multicenter Randomized Clinical Trial Protocol (Destination Cardiac Rehab Study)","Inclusion Criteria:\n\n* Indication for CR according to Centers for Medicare \\& Medicaid Services (CMS) guidelines:\n\n  * Myocardial infarction within the preceding 12 months\n  * Coronary artery bypass surgery\n  * Current stable angina (chest pain)\n  * Heart valve repair or replacement\n  * Percutaneous transluminal coronary angioplasty (PTCA) or coronary stenting\n  * Heart or heart-lung transplant\n  * Stable chronic heart failure\n* Aged ≥18 years\n* Basic Internet navigation skills\n* Active email address\n\nExclusion Criteria:\n\n* High risk patients according to the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) risk stratification103 given safety concern of unsupervised exercise:\n\n  * Sudden cardiac arrest survivor\n  * Receiving continuous inotropic support\n  * Presence of a mechanical circulatory support device\n  * Decompensated heart failure\n  * Symptomatic valvular heart disease\n  * Uncontrolled angina\n  * Presence of hemodynamically unstable dysrhythmias (e.g., ventricular tachycardia)\n* Pregnant (due to associated hormonal and weight changes)\n* Non-English-speaking\n* Visual\u002Fhearing impairment or mental disability that would preclude independent use of the VW platform","ALL","18 Years",{"count":106,"type":107},150,"ESTIMATED","INTERVENTIONAL",[110],"NA","The purpose of this research is to compare health outcomes and participation between a virtual world cardiac rehabilitation (Destination Cardiac Rehab) program and the standard of care Center-based Cardiac Rehabilitation program. Destination Cardiac Rehab, developed with input from patients with heart disease and their caregivers, is a 3-D, interactive program offering an affordable telehealth option for cardiac rehabilitation (cardiac rehab) that can be done from home or any place that you can access the Internet with a computer.",[113],"Heart Diseases","NOT_YET_RECRUITING","2026-07-30",{"date":117,"type":118},"2026-08-04","ACTUAL",{"date":120,"type":107},"2026-08",{"date":122,"type":107},"2028-08",{"name":5,"class":6},3]