[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648516":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":110,"centralContacts":114,"locations":120,"responsibleParty":138,"collaborators":141,"id":144,"slug":145,"hasResults":146,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":66,"eligibilityCriteria":150,"healthyVolunteers":146,"sex":151,"minAge":152,"maxAge":153,"enrollmentInfo":154,"targetDuration":66,"studyType":157,"phases":158,"briefSummary":160,"conditions":161,"keywords":66,"overallStatus":169,"whyStopped":66,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":179},{"fullName":5,"class":6},"Ohio State University Comprehensive Cancer Center","OTHER",[8,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I (web-based lifestyle program, virtual group)","EXPERIMENTAL","PHASE I (WEEKS 1-4): Patients complete self-paced web-based lifestyle program modules over 45-90 minutes weekly for 4 weeks. Patients adhere to a personalized diet meeting AICR guidelines and receive access to online resources, including AICR resources, online cooking class videos, healthy eating recipes and tips. Patients participate in moderate-intensity aerobic physical activity over 10-30 minutes on 5 days weekly and resistance training over 30 minutes on 2-3 times weekly.\n\nPHASE II (WEEKS 5-26): Patients continue web-based program modules, exercise program and diet recommendations as in Phase I. Patients also attend virtual group sessions over 45-50 minutes weekly for weeks 5-26.\n\nPatients may also participate in a focus group over 30-45 minutes on study. Additionally, patients undergo urine and blood sample collection throughout the study.",[13,14,15,16,17,18,19,20],"Other: Aerobic Exercise","Procedure: Biospecimen Collection","Other: Dietary Intervention","Other: Discussion","Other: Internet-Based Intervention","Other: Questionnaire Administration","Other: Resistance Training","Other: Supportive Care",{"label":22,"type":10,"description":23,"interventionNames":24},"Group II (web-based lifestyle, JITAI)","PHASE I (WEEKS 1-4): Patients complete self-paced web-based lifestyle program modules over 45-90 minutes weekly for 4 weeks. Patients adhere to a personalized diet meeting AICR guidelines and receive access to online resources, including AICR resources, online cooking class videos, healthy eating recipes and tips. Patients participate in moderate-intensity aerobic physical activity over 10-30 minutes on 5 days weekly and resistance training over 30 minutes on 2-3 times weekly.\n\nPHASE II (WEEKS 5-26): Patients continue web-based program modules, exercise program and diet recommendations as in Phase I. Patients also set goals for behavioral changes weekly and receive JITAI tailored resource components via mHealth + EMA during weeks 5-26. Patients wear a physical activity tracker daily and receive access to the Fitbit App.\n\nPatients may also participate in a focus group over 30-45 minutes on study. Patients undergo urine and blood sample collection throughout the study.",[13,14,15,16,25,17,26,18,19,27,20,28],"Other: Goal Setting","Other: Medical Device Usage and Evaluation","Behavioral: Smartphone Application-based Intervention","Procedure: Tailored Intervention",[30,36,46,56,62,67,71,75,79,85,94,102,106],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Aerobic Exercise","Participate in moderate-intensity aerobic physical activity",[9,22],[35],"Aerobic Activity",{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":41},"PROCEDURE","Biospecimen Collection","Undergo urine and blood sample collection",[9,22],[42,43,44,45],"Biological Sample Collection","Biospecimen Collected","Sample Collection","Specimen Collection",{"type":6,"name":47,"description":48,"armGroupLabels":49,"otherNames":50},"Dietary Intervention","Adhere to a personalized diet",[9,22],[51,52,53,54,55],"Dietary Modification","intervention, dietary","Nutrition Intervention","Nutrition Interventions","Nutritional Interventions",{"type":6,"name":57,"description":58,"armGroupLabels":59,"otherNames":60},"Discussion","Participate in a focus group",[9,22],[61],"Discuss",{"type":6,"name":63,"description":64,"armGroupLabels":65,"otherNames":66},"Goal Setting","Set goals for behavioral changes",[22],null,{"type":6,"name":68,"description":69,"armGroupLabels":70,"otherNames":66},"Internet-Based Intervention","Complete self-paced web-based lifestyle program modules",[9,22],{"type":6,"name":72,"description":73,"armGroupLabels":74,"otherNames":66},"Medical Device Usage and Evaluation","Wear a physical activity tracker",[22],{"type":6,"name":76,"description":77,"armGroupLabels":78,"otherNames":66},"Questionnaire Administration","Ancillary studies",[9,22],{"type":6,"name":80,"description":81,"armGroupLabels":82,"otherNames":83},"Resistance Training","Participate in resistance training",[9,22],[84],"Strength Training",{"type":86,"name":87,"description":88,"armGroupLabels":89,"otherNames":90},"BEHAVIORAL","Smartphone Application-based Intervention","Receive access to the Fitbit app",[22],[91,92,93],"Smartphone App-based Intervention","Smartphone Intervention","Smartphone-based Intervention",{"type":6,"name":95,"description":96,"armGroupLabels":97,"otherNames":98},"Supportive Care","Receive access to online resources",[9,22],[99,100,101],"Supportive Therapy","Symptom Management","Therapy, Supportive",{"type":6,"name":95,"description":103,"armGroupLabels":104,"otherNames":105},"Attend virtual group sessions",[9],[99,100,101],{"type":37,"name":107,"description":108,"armGroupLabels":109,"otherNames":66},"Tailored Intervention","Receive JITAI tailored resource components",[22],[111],{"name":112,"affiliation":5,"role":113},"Xiaochen Zhang, PhD","PRINCIPAL_INVESTIGATOR",[115],{"name":116,"role":117,"phone":118,"phoneExt":66,"email":119},"The Ohio State University Comprehensive Cancer Center","CONTACT","800-293-5066","OSUCCCClinicaltrials@osumc.edu",[121],{"facility":5,"status":66,"city":122,"state":123,"zip":124,"country":125,"countryCode":126,"cosmosGeoPoint":127,"geoPoint":132,"contacts":133},"Columbus","Ohio","43210","United States","US",{"type":128,"coordinates":129},"Point",[130,131],-82.99879,39.96118,{"lat":131,"lon":130},[134,137],{"name":112,"role":117,"phone":135,"phoneExt":66,"email":136},"614-685-0624","Xiaochen.Zhang@osumc.edu",{"name":112,"role":113,"phone":66,"phoneExt":66,"email":66},{"type":113,"investigatorFullName":139,"investigatorTitle":140,"investigatorAffiliation":5,"oldNameTitle":66,"oldOrganization":66},"Xiaochen Zhang","Principal Investigator",[142],{"name":143,"class":6},"American Association for Cancer Research","100648516","web-based-lifestyle-program-mhealth-and-ema-intervention-to-improve-weight-loss-in-rural-stage-i-iii-postmenopausal-breast-and-endometrial-cancer-survivors-hero-c-trial-100648516",false,"NCT07723235","Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial","Health Engagement for Rural Ohio Cancer Survivors (HERO-C)","Inclusion Criteria:\n\n* Body mass index (BMI) ≥ 25kg\u002Fm\\^2\n* Age: 40-69 years\n* 1-5 years post-diagnosis of stage I-III postmenopausal breast cancer or stage I-III endometrial cancer\n* No known evidence of recurrence (local or distant) or second, primary cancer\n* No prior history of new other malignancy since their breast or endometrial cancer diagnosis (other than non-melanoma skin cancer)\n* Not currently participating in any weight loss programs, no personal trainer, and not meeting the physical activity guidelines\n* No use of any anti-obesity medications in the last 6 months and no plan to start anti-obesity medications during the study period\n* The ability to walk two blocks without a walker or cane\n* The ability to speak and read English\n* Have access to internet with a computer, tablet, or smart phone\n* Live in rural counties in Ohio and not planning to move away during the study\n* Are not pregnant, breastfeeding or less than 12-month post-partum and do not plan to become pregnant during the study\n\nExclusion Criteria:\n\n* Severe medical conditions, such as unstable cardiovascular disease or digestive disorders, that would preclude physical activity and dietary intervention\n* Lack of physician clearance if determined necessary by the Physical Activity Readiness Questionnaire (PAR-Q+)\n* Acute physical limitations for unsupervised exercises at home\n* Unable to give informed consent","FEMALE","40 Years","69 Years",{"count":155,"type":156},90,"ESTIMATED","INTERVENTIONAL",[159],"NA","This clinical trial identifies the needs and preferences of rural stage I-III postmenopausal breast and endometrial cancer survivors and evaluates the impact of an adaptive, online program, mobile (m)Health + ecological momentary assessment (EMA) intervention, on lifestyle modification and their weight loss efforts. Obesity, a condition marked by an abnormally high, unhealthy amount of body fat, is associated with lower physical and psychological well-being, higher risk of recurrence, and higher cancer-specific and all-cause mortality (number of deaths). Lifestyle factors, such as low physical activity and unhealthy diet, are the main contributors to obesity that are modifiable. Lifestyle weight loss programs focusing on modifiable factors can improve cancer-specific survival and many aspects of health, but access to these programs can be challenging in rural settings. A remote lifestyle program, adapted to individual goals and needs, may help promote healthy behaviors, improve cancer outcomes, and reduce disease burden in stage I-III postmenopausal breast and endometrial cancer survivors.",[162,163,164,165,166,167,168],"Anatomic Stage I Breast Cancer AJCC v8","Anatomic Stage II Breast Cancer AJCC v8","Anatomic Stage III Breast Cancer AJCC v8","Endometrial Carcinoma","Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8","Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8","Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8","NOT_YET_RECRUITING","2026-07-20",{"date":172,"type":173},"2026-07-23","ACTUAL",{"date":175,"type":156},"2026-10-10",{"date":177,"type":156},"2027-12-31",{"name":5,"class":6},1]