[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645575":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":37,"locations":47,"responsibleParty":73,"collaborators":26,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":26,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":26,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":50,"whyStopped":26,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"University of Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"interventional group A","EXPERIMENTAL","The experimental group A will receive weighted dangling exercise. A gravity-assisted flexion-extension movements of the lower legs Ankle cuffs weight worn during the exercise while seated on a high couch with their legs hanging down",[13],"Behavioral: interventional group B",{"label":15,"type":16,"description":17,"interventionNames":18},"interventional group B","ACTIVE_COMPARATOR","Experimental group B receive neuromuscular electrical stimulation (NMES) specifically targeting the vastus medialis oblique (VMO). The NMES parameters are as follows: electrodes were placed above the superomedial border of the patella, oriented at a 55° angle to the vertical. The stimulation frequency set at 50 Hz, with a pulse duration of 250 µs and a duty cycle of 10 seconds ON and 30 seconds OFF",[19],"Behavioral: Interventional group A",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Interventional group A","The one group will receive weighted dangling exercise. A gravity-assisted flexion-extension movements of the lower legs Ankle cuffs weight worn during the exercise while seated on a high couch with their legs hanging down",[15],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"This group receive neuromuscular electrical stimulation (NMES) specifically targeting the vastus medialis oblique (VMO). The NMES parameters are as follows: electrodes were placed above the superomedial border of the patella, oriented at a 55° angle to the vertical. The stimulation frequency set at 50 Hz, with a pulse duration of 250 µs and a duty cycle of 10 seconds ON and 30 seconds OFF",[9],[31,35],{"name":32,"affiliation":33,"role":34},"Mahnoor Fatima, MS MSK*","University Institute of Physical Therapy, University of Lahore","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":33,"role":34},"Hafiza Sana Ashraf, PhD PT*",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},"Ishaq Ahmed, PhD PT","CONTACT","03344066463","ishaq.ahmed@uipt.uol.edu.pk",{"name":44,"role":40,"phone":45,"phoneExt":26,"email":46},"Ashfaq Ahmed, PhD PT","03009449192","ashfaq.ahmed@uipt.uol.edu.pk",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"University of Lahore Teaching Hospital, Lahore, Pakistan","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":57,"coordinates":58},"Point",[59,60],74.35071,31.558,{"lat":60,"lon":59},[63,67,70,72],{"name":64,"role":40,"phone":65,"phoneExt":26,"email":66},"Asim Arif, PhD PT*","03216597727","asim.arif@uipt.uol.edu.pk",{"name":32,"role":40,"phone":68,"phoneExt":26,"email":69},"03164247896","70174837@student.uol.edu.pk",{"name":71,"role":34,"phone":26,"phoneExt":26,"email":26},"Mahnoor Fatima, MS MSK",{"name":36,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":34,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Mahnoor Fatima","Principle investigator","100645575","weighted-dangling-exercises-vs-vastus-medialis-oblique-muscle-neuromuscular-stimulation-for-knee-osteoarthritis-100645575",false,"NCT07701174","Weighted Dangling Exercises vs Vastus Medialis Oblique Muscle Neuromuscular Stimulation for Knee Osteoarthritis","Effectiveness of Weighted Dangling Exercises Versus Vastus Medialis Oblique Muscle Neuromuscular Stimulation in Patients With Knee Osteoarthritis","Inclusion Criteria:\n\nBoth genders and aged between 40 and 60 years. Symptoms of unilateral knee pain and crepitus persist for at least 6 months during ascending and descending motion. Radiographic KOA; grade 2 or more according to Kellgren and Lawrence scale. Patient referred by an orthopedic physician Those who have taken oral corticosteroids within the last month or who received intra-articular corticosteroid injection or analgesic injection intervention for hip or knee pain within the last 3 month\n\nExclusion Criteria:\n\n* Recent surgery (within three months) history of hip or knee joint replacement, tibial osteotomy, orthoses with systemic arthritis, history of trauma such as knee fracture and other with muscular disease of neurological disorders that would affect lower extremity function is excluded.","ALL","40 Years","60 Years",{"count":87,"type":88},48,"ESTIMATED","INTERVENTIONAL",[91],"NA","This randomized controlled trial aims to compare the effectiveness Weighted dangling exercises versus vastus medialis oblique muscle neuromuscular electrical stimulation(VMO+NMES) in patients with knee osteoarthritis. The study will recruit 48 participants (accounting for 10% attrition), aged 40-60 years, from University of Lahore Teaching Hospital using convenience sampling. Participants will be randomly allocated into two groups: an interventional group receiving WDE and other interventional group undergoing VMO strength training with NMES. Both interventions will be administered three times per week for 8 weeks under professional supervision. Outcome measures including pain intensity (NPRS), Functional Disability (Western Ontario and McMaster Universities Osteoarthritis Index),Muscle Strength (MMT) will be assessed at baseline, 4 weeks, and 8 weeks. Data will be analyzed using SPSS, with appropriate parametric or non-parametric tests applied after checking data normality. Ethical approval will be obtained, informed consent will be secured, and participant confidentiality will be strictly maintained.",[94],"Osteoarthritis",[96],"Knee Osteoarthritis","2026-07-08",{"date":99,"type":100},"2026-07-14","ACTUAL",{"date":102,"type":100},"2026-05-25",{"date":104,"type":88},"2026-09-10",{"name":5,"class":6},1]