[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655848":3},{"organization":4,"outcomesModule":7,"designInfo":44,"detailedDescription":43,"studyPopulation":43,"armGroups":52,"interventions":65,"overallOfficials":75,"centralContacts":80,"locations":90,"responsibleParty":271,"collaborators":274,"id":300,"slug":301,"hasResults":302,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":68,"eligibilityCriteria":306,"healthyVolunteers":302,"sex":307,"minAge":308,"maxAge":43,"enrollmentInfo":309,"targetDuration":43,"studyType":312,"phases":313,"briefSummary":315,"conditions":316,"keywords":320,"overallStatus":93,"whyStopped":43,"lastUpdateSubmitDate":326,"lastUpdatePostDateStruct":327,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":335},{"fullName":5,"class":6},"Centre for Chronic Disease Control, India","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":43},[9,13],{"measure":10,"description":11,"timeFrame":12},"Major Adverse Cardiovascular event","Time to first cardiovascular event","Median follow-up of 1 year",{"measure":14,"description":15,"timeFrame":16},"Heart Failure Specific Quality of life","Change in the Minnesota Living with Heart Failure Questionnaire (MLHFQ) total score from baseline. The MLHFQ consists of 21 items, each scored from 0 (no impact) to 5 (very much impacted), with a total score ranging from 0 to 105. Lower scores indicate better health-related quality of life","3 months",[18,21,24,27,30,33,36,40],{"measure":19,"description":20,"timeFrame":16},"Six minute walk test","Six-minute walk distance (6MWD), measured as the total distance in metres walked by the participant during a standardized six-minute walk test. A greater distance indicates better functional exercise capacity.",{"measure":22,"description":23,"timeFrame":16},"Generic Quality of life","European Quality of Life (EQ-5D-5L) Questionnaire evaluates five dimensions: mobility, self-care, usual activities, pain\u002Fdiscomfort, and anxiety\u002Fdepression. Each dimension has five response levels. The outcome will be expressed as the EQ-5D-5L utility index score, with higher scores indicating better health-related quality of life.",{"measure":25,"description":26,"timeFrame":16},"Self-rated health (EQ-5D-5L)","EQ-VAS score, ranging from 0 to 100, where 0 represents the worst imaginable health state and 100 represents the best imaginable health state. Higher scores indicate better perceived health status.",{"measure":28,"description":29,"timeFrame":16},"Tobacco cessation","Smoking cessation will be assessed based on self-reported tobacco use status. Current smokers at baseline who report no tobacco use at follow-up will be classified as having achieved tobacco cessation.",{"measure":31,"description":32,"timeFrame":16},"Self-reported Frailty","Frailty assessed by Fried Frailty Phenotype tool",{"measure":34,"description":35,"timeFrame":16},"Caregiver's depression - Patient Health Questionnaire-9","PHQ-9 total score, ranging from 0 to 27, with each of the nine items scored from 0 to 3. Higher scores indicate greater severity of depressive symptoms.",{"measure":37,"description":38,"timeFrame":39},"Caregiver's Quality of Life - EQ-5D-5L","Quality of life will be assessed using the EQ-5D-5L questionnaire, which evaluates five dimensions: mobility, self-care, usual activities, pain\u002Fdiscomfort, and anxiety\u002Fdepression. Each dimension has five response levels. The outcome will be expressed as the EQ-5D-5L utility index score and visual analogue scale (EQ-VAS), with higher scores indicating better health-related quality of life.","at 3 months",{"measure":41,"description":42,"timeFrame":12},"Costs of care","Cost effectiveness as assessed by a piloted tool",null,{"allocation":45,"interventionModel":46,"interventionModelDescription":43,"primaryPurpose":47,"observationalModel":43,"timePerspective":43,"maskingInfo":48},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":49,"maskingDescription":43,"whoMasked":50},"SINGLE",[51],"OUTCOMES_ASSESSOR",[53,60],{"label":54,"type":55,"description":56,"interventionNames":57},"Yoga-CaRe group","EXPERIMENTAL","Yoga based cardiac rehabilitation programme delivered as 20 sessions spread over three months and long term care and follow-up.",[58,59],"Behavioral: Yoga-CaRe HF","Behavioral: Health Education",{"label":61,"type":62,"description":63,"interventionNames":64},"Enhanced standard care","ACTIVE_COMPARATOR","Enhanced standard care comprising of health education delivered in 3 sessions spread over three months.",[59],[66,71],{"type":67,"name":68,"description":69,"armGroupLabels":70,"otherNames":43},"BEHAVIORAL","Yoga-CaRe HF","A cardiac rehabilitation programme comprising of health education and yogic practices.",[54],{"type":67,"name":72,"description":73,"armGroupLabels":74,"otherNames":43},"Health Education","Health education on \"Healthy Living with Heart Failure\"",[61,54],[76],{"name":77,"affiliation":78,"role":79},"Dorairaj Prabhakaran, MD DM (Cardiology)","Centre for Chronic Disease Control, New Delhi","PRINCIPAL_INVESTIGATOR",[81,86],{"name":82,"role":83,"phone":84,"phoneExt":43,"email":85},"Dorairaj Prabhakaran, MD DM","CONTACT","+91 11 41618456","dprabhakaran@ccdcindia.org",{"name":87,"role":83,"phone":84,"phoneExt":88,"email":89},"Ambalam M Chandrasekaran, BNYS MPH","4804","Chandrasekaran@ccdcindia.org",[91,108,120,133,144,157,167,180,189,202,214,226,234,246,255,263],{"facility":92,"status":93,"city":94,"state":95,"zip":96,"country":97,"countryCode":98,"cosmosGeoPoint":99,"geoPoint":104,"contacts":105},"SDM College of Medical Sciences & Hospital","RECRUITING","Dharwad","Karnataka","580009","India","IN",{"type":100,"coordinates":101},"Point",[102,103],75.00778,15.46005,{"lat":103,"lon":102},[106],{"name":107,"role":83,"phone":43,"phoneExt":43,"email":43},"Kiran Aithal, MD General Medicine",{"facility":109,"status":93,"city":110,"state":95,"zip":111,"country":97,"countryCode":98,"cosmosGeoPoint":112,"geoPoint":116,"contacts":117},"JSS Hospital","Mysore","570004",{"type":100,"coordinates":113},[114,115],76.63925,12.29791,{"lat":115,"lon":114},[118],{"name":119,"role":83,"phone":43,"phoneExt":43,"email":43},"Sunil Kumar S, DM Cardiology",{"facility":121,"status":93,"city":122,"state":123,"zip":124,"country":97,"countryCode":98,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"North Eastern Indira Gandhi Regional Institute of Medical Sciences","Shillong","Meghālaya","793018",{"type":100,"coordinates":126},[127,128],91.88313,25.56892,{"lat":128,"lon":127},[131],{"name":132,"role":83,"phone":43,"phoneExt":43,"email":43},"Amit Malviya, DM Cardiology",{"facility":134,"status":135,"city":136,"state":137,"zip":138,"country":97,"countryCode":98,"cosmosGeoPoint":139,"geoPoint":143,"contacts":43},"All India Institute of Medical Sciences","ACTIVE_NOT_RECRUITING","New Delhi","National Capital Territory of Delhi","110029",{"type":100,"coordinates":140},[141,142],77.2148,28.62137,{"lat":142,"lon":141},{"facility":145,"status":93,"city":146,"state":147,"zip":148,"country":97,"countryCode":98,"cosmosGeoPoint":149,"geoPoint":153,"contacts":154},"Dayanand Medical College and Hospital","Ludhiana","Punjab","141001",{"type":100,"coordinates":150},[151,152],75.85379,30.91204,{"lat":152,"lon":151},[155],{"name":156,"role":83,"phone":43,"phoneExt":43,"email":43},"Bishav Mohan, DM Cardiology",{"facility":134,"status":158,"city":159,"state":160,"zip":161,"country":97,"countryCode":98,"cosmosGeoPoint":162,"geoPoint":166,"contacts":43},"SUSPENDED","Jodhpur","Rajasthan","342005",{"type":100,"coordinates":163},[164,165],73.00594,26.26841,{"lat":165,"lon":164},{"facility":168,"status":93,"city":169,"state":170,"zip":171,"country":97,"countryCode":98,"cosmosGeoPoint":172,"geoPoint":176,"contacts":177},"Madras Medical College","Chennai","Tamil Nadu","600003",{"type":100,"coordinates":173},[174,175],80.27847,13.08784,{"lat":175,"lon":174},[178],{"name":179,"role":83,"phone":43,"phoneExt":43,"email":43},"G Justin Paul, DM Cardiology",{"facility":181,"status":93,"city":169,"state":170,"zip":182,"country":97,"countryCode":98,"cosmosGeoPoint":183,"geoPoint":185,"contacts":186},"Sri Ramchandra Institute of Higher Education and Research","600116",{"type":100,"coordinates":184},[174,175],{"lat":175,"lon":174},[187],{"name":188,"role":83,"phone":43,"phoneExt":43,"email":43},"Nagendra Boopathy, DM Cardiology",{"facility":190,"status":93,"city":191,"state":192,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":193,"geoPoint":197,"contacts":198},"All India Institute of Medical Sciences, Rishikesh","Rishikesh","Uttarakand",{"type":100,"coordinates":194},[195,196],78.29255,30.10778,{"lat":196,"lon":195},[199],{"name":200,"role":83,"phone":43,"phoneExt":43,"email":201},"Bhanu Duggal","bhanu.cardio@aiimsrishikesh.edu.in",{"facility":203,"status":93,"city":204,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"Sri Jayadeva Institute of Cardiovascular Sciences and Research","Bangalore",{"type":100,"coordinates":206},[207,208],77.59369,12.97194,{"lat":208,"lon":207},[211],{"name":212,"role":83,"phone":43,"phoneExt":43,"email":213},"Prabhavathi","prabhavathi_in@yahoo.com",{"facility":215,"status":93,"city":216,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":217,"geoPoint":221,"contacts":222},"All India Institute of Medical Sciences, Bathinda","Bathinda",{"type":100,"coordinates":218},[219,220],74.93893,30.20747,{"lat":220,"lon":219},[223],{"name":224,"role":83,"phone":43,"phoneExt":43,"email":225},"Bhupinder Singh","docbhupi@gmail.com",{"facility":227,"status":158,"city":228,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":229,"geoPoint":233,"contacts":43},"KLES Dr. Prabhakar Kore Charitable Hospital","Belagavi",{"type":100,"coordinates":230},[231,232],74.50447,15.85212,{"lat":232,"lon":231},{"facility":235,"status":93,"city":236,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":237,"geoPoint":241,"contacts":242},"Safdarjung Hospital","Delhi",{"type":100,"coordinates":238},[239,240],77.23149,28.65195,{"lat":240,"lon":239},[243],{"name":244,"role":83,"phone":43,"phoneExt":43,"email":245},"Anunay Gupta","dranunaygupta@gmail.com",{"facility":247,"status":93,"city":236,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":248,"geoPoint":250,"contacts":251},"Sir Ganga Ram Hospital",{"type":100,"coordinates":249},[239,240],{"lat":240,"lon":239},[252],{"name":253,"role":83,"phone":43,"phoneExt":43,"email":254},"Subhash Chand Manchanda","doctormanchanda@yahoo.com",{"facility":203,"status":93,"city":110,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":256,"geoPoint":258,"contacts":259},{"type":100,"coordinates":257},[114,115],{"lat":115,"lon":114},[260],{"name":261,"role":83,"phone":43,"phoneExt":43,"email":262},"Sadanand K S","sadanand_dm@rediffmail.com",{"facility":264,"status":158,"city":265,"state":43,"zip":43,"country":97,"countryCode":98,"cosmosGeoPoint":266,"geoPoint":270,"contacts":43},"Acharya Vinobha Bhave Rural Hospital","Wardha",{"type":100,"coordinates":267},[268,269],78.59784,20.73933,{"lat":269,"lon":268},{"type":79,"investigatorFullName":272,"investigatorTitle":273,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"Dr. Dorairaj Prabhakaran","Director",[275,278,281,282,283,284,286,287,289,291,292,294,296,297,299],{"name":276,"class":277},"Indian Council of Medical Research","OTHER_GOV",{"name":279,"class":280},"Central Council for Research in Yoga & Naturopathy","UNKNOWN",{"name":134,"class":6},{"name":215,"class":277},{"name":190,"class":277},{"name":285,"class":277},"All India Institute of Medical Sciences, Jodhpur",{"name":145,"class":6},{"name":288,"class":280},"KLES Prabhakar Kore Hospital Belagavi",{"name":290,"class":280},"JSS Medical College Hospital",{"name":92,"class":6},{"name":293,"class":277},"North Eastern Indira Gandhi Regional Institute of Health ans Medical Sciences",{"name":295,"class":6},"Sri Ramachandra Institute of Higher Education and Research",{"name":168,"class":277},{"name":298,"class":280},"Acharya Vinoba Bhave Rural Hospital",{"name":203,"class":6},"100655848","yoga-based-cardiac-rehabilitation-in-heart-failure-failure-100655848",false,"NCT07817589","Yoga Based Cardiac Rehabilitation in Heart Failure Failure","Effectiveness of Yoga Based Cardiac Rehabilitation (Yoga-CaRe) in Heart Failure: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Male and female patients above 18years\n* Physician diagnosed heart failure patients with reduced ejection fraction based on ESC guidelines\n* Patients should be NYHA class II\u002FIII\n* Willing and able to attend the complete hospital-based CR programme on their own\n\nExclusion Criteria:\n\n* Comorbid disease or behavioral or other limitations that interfere with performing Yoga training or prevent the completion of 1 y of exercise training\n* Elective Cardiovascular procedure or hospitalization planned in the coming 3 months\n* Currently pregnant or intend to become pregnant in the next year\n* Heart failure secondary to significant correctable\u002Freversible cause like primary valvular disease\u002F correctable congential heat disease\n* Performance of exercise training\u002Fyoga at regular intervals (more than once per week) at a moderate-to-vigorous intensity at any time in the previous 6 week\n* Participation in other clinical trials","ALL","18 Years",{"count":310,"type":311},3500,"ESTIMATED","INTERVENTIONAL",[314],"NA","The clinical study compares the benefits of yoga based rehabilitation programme versus an educational package during recovery of patients with heart failure. Cardiac rehabilitation programmes help patients with cardiac illness to return as quickly as possible to full and productive life and to reduce the chances of further cardiac illness or death. We want to know whether our package of yoga classes can provide effective cardiac rehabilitation and how that compares with a package of educational classes. Both packages are especially designed by us to improve heart health",[317,318,319],"Heart Failure With Reduced Ejection Fraction","Heart Failure NYHA Class II","Heart Failure NYHA Class III",[321,322,323,324,325],"Heart failure","Yoga","Yoga-CaRe","cardiac rehabilitation","rehabilitation","2026-09-07",{"date":328,"type":329},"2026-09-14","ACTUAL",{"date":331,"type":329},"2023-04-24",{"date":333,"type":311},"2026-11-30",{"name":5,"class":6},16]