[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658146":3},{"organization":4,"outcomesModule":7,"designInfo":46,"detailedDescription":57,"studyPopulation":51,"armGroups":58,"interventions":69,"overallOfficials":51,"centralContacts":51,"locations":51,"responsibleParty":79,"collaborators":83,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":89,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":51,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":51,"overallStatus":112,"whyStopped":51,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":51},{"fullName":5,"class":6},"Seattle Children's Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":25,"otherOutcomes":42},[9,13,16,19,23],{"measure":10,"description":11,"timeFrame":12},"Overdose Prevention Knowledge","Youth knowledge on how to prevent and\u002For respond to an overdose. Assessed using the Opioid Overdose Knowledge Scale (OOKS). Scores range from 0-45 and a higher score is considered a better outcome.","3- and 6-months",{"measure":14,"description":15,"timeFrame":12},"Presence of use past 30 days (Yes\u002FNo)","Use of any overdose associated substance (opioids, benzodiazepines, alcohol, or stimulants) in the past 30 days; use of any substance in the past 30 days",{"measure":17,"description":18,"timeFrame":12},"Number of days using alcohol and cannabis","In the past 30 days, number of days youth used cannabis; in the past 30 days, number of days youth used alcohol.",{"measure":20,"description":21,"timeFrame":22},"Number of youth receiving case management, mental health, or substance use prevention services","Primary implementation outcome - county level","Through study completion, up to 30 months",{"measure":24,"description":21,"timeFrame":22},"Number of naloxone kits distributed",[26,30,33,37,40],{"measure":27,"description":28,"timeFrame":29},"Number of days of using other individual non-alcohol\u002Fnon-cannabis substances","Measure taken from the HEAL Prevention Cooperative Common Core Measures","3- and 6- months",{"measure":31,"description":32,"timeFrame":12},"Substance use refusal self-efficacy","How confident youth are resisting substances.",{"measure":34,"description":35,"timeFrame":36},"Percent of youth reporting receipt of naloxone","Percent of youth receiving naloxone, a medication to reverse an opioid overdose.","3 months",{"measure":38,"description":39,"timeFrame":22},"Number of youth receiving overdose prevention education","Secondary implementation outcome - county level",{"measure":41,"description":39,"timeFrame":22},"Number of court staff receiving overdose prevention education",[43],{"measure":44,"description":45,"timeFrame":12},"Presence of non-fatal overdose","Exploratory outcome, investigator-developed",{"allocation":47,"interventionModel":48,"interventionModelDescription":49,"primaryPurpose":50,"observationalModel":51,"timePerspective":51,"maskingInfo":52},"RANDOMIZED","CROSSOVER","Stepped Wedge, Unidirectional Crossover Design","HEALTH_SERVICES_RESEARCH",null,{"masking":53,"maskingDescription":51,"whoMasked":54},"DOUBLE",[55,56],"INVESTIGATOR","OUTCOMES_ASSESSOR","Youth involved in the legal system (YILS) have some of the highest rates of substance and opioid use disorders (SUD\u002FOUD) nationally; but few have access to adequate resources to prevent serious sequelae. SUD prevention and overdose prevention interventions for YILS are critically important to delay escalation to synthetic opioids and prevent fatalities and other health, and legal consequences.\n\nWashington State is facing an overdose crisis; between August 2022 and 2023, overdose deaths in this state increased by 40%, a steeper increase than any other state. Rural counties in this state report overdose rates that are as high or higher than urban ones. YILS, even those without OUD, are especially vulnerable to unintentional overdose; amongst YILS incarcerated in Washington State system completing a drug and alcohol assessment, 58% had experienced an overdose at some point in the past (unpublished data). Substance use resources in this and other states for rural YILS are critical and sparse.\n\nWorking with counties on a prevention strategy will further the goal of intervening with YILS who are, on average, earlier in the spectrum of legal and substance use involvement. Prior to this trial, the research team completed a codesign process with various stakeholders to design an intervention. Codesign invites people with lived experience to the design process with the goal of designing a more effective intervention. The codesign group consisted of youth and caregivers with lived experience with substance use or the juvenile court system, behavioral health providers, funding sector representatives, and juvenile county court administrators.Participating counties will be randomized into 6 clusters of the stepped wedge design. Control group participant data collection will begin for all counties at the same time. Clusters of counties will step into the implementation stage every 3-months. When counties move into the implementation stage, intervention group participant data collection will immediately begin.",[59,65],{"label":60,"type":61,"description":62,"interventionNames":63},"Intervention: YOURS Navigator Program","EXPERIMENTAL","The intervention consists of a navigator stationed in each participating county or shared by neighboring counties. The navigator will deliver a flexible care management intervention, including direct services and referrals to court-involved youth in rural Washington counties.",[64],"Behavioral: Navigator - Flexible Care Management",{"label":66,"type":67,"description":68,"interventionNames":51},"Usual Care","NO_INTERVENTION","No Navigator intervention during the control time period. The juvenile court system may refer adolescents to their usual care pathways.",[70],{"type":71,"name":72,"description":73,"armGroupLabels":74,"otherNames":75},"BEHAVIORAL","Navigator - Flexible Care Management","Care Navigator who will work with youth and families to address mental health, substance use, and other unmet needs, both through direct support services as well as referrals to adjunctive agencies. The flexible care management intervention may include goal setting, skill building, contingency management, motivational interviewing, overdose prevention and education, mental health and substance first aid, and basic needs support. The Navigator will work closely with the youth for 3-months, and as-needed up to 6-months.",[60],[76,77,78],"Care Management","ACRA\u002FACC","Assertive Continuing Care (ACC)",{"type":80,"investigatorFullName":81,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":51,"oldOrganization":51},"PRINCIPAL_INVESTIGATOR","Kym Ahrens","Principal Investigator",[84],{"name":85,"class":86},"National Institute on Drug Abuse (NIDA)","NIH","100658146","youth-overdose--use-reduction-in-rural-systems-100658146",false,"NCT07846735","Youth Overdose & Use Reduction in Rural Systems","YOURS Study: Youth Overdose & Use Reduction in Rural Systems","YOURS","Inclusion Criteria:\n\n* Youth age 14-18\n* Current juvenile court-involvement or receiving services from a participating county court (includes detention, diversion, truancy, at-risk youth, etc.)\n* Received a REDCap link or QR code and study participation code from authorized county staff\n\nExclusion Criteria:\n\n* Youth age 13 and under\n* Youth who do not receive a study participation code from an authorized county contact\n* Unable to participate due to significant mental health or developmental issue precluding meaningful participation in study procedures and\u002For intervention","ALL","14 Years","18 Years",{"count":99,"type":100},550,"ESTIMATED","INTERVENTIONAL",[103],"NA","The goal of this study is to conduct a clinical trial to understand effects of providing multilevel intervention to young people in the legal system. The multilevel intervention includes flexible care management using ACRA\u002FACC principles, family support, and overdose education. This study aims to test the implementation strategy, as well as the outcomes of the intervention with participants.\n\nThe first question the study will address is how successful was implementation. This will be measured by the number of youth receiving case management, family support, naloxone supplies, and overdose prevention curricula, and adoption by the participating county court systems.\n\nThe second question the study will address is whether the intervention impacted youth behavioral outcomes, such as overdose risk awareness, knowledge of how to use naloxone, and number of days per month using substances.\n\nResearchers will compare youth who received the intervention to youth who received usual treatment to see if the intervention increases overdose risk awareness and knowledge, and decreases frequency of substance use.\n\nParticipants will receive the intervention (if assigned to) and complete study surveys. Participating counties will provide data on implementation, and site visits will also be performed to track each county's performance.",[106,107,108,109,110,111],"Substance Abuse","Opioid Abuse (Disorder)","Overdose Prevention","Substance Use Disorder (SUD)","Adolescent Substance Use","Rural Health","NOT_YET_RECRUITING","2026-09-22",{"date":115,"type":116},"2026-09-29","ACTUAL",{"date":118,"type":100},"2026-10",{"date":120,"type":100},"2029-02",{"name":5,"class":6}]