[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Acibadem University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":680},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,41,0,25,[9,48,72,100,123,158,189,208,225,240,261,283,310,329,363,391,426,458,485,516,539,570,599,621,651],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100546749","the-effect-of-cognitive-exercise-therapy-approach-and-yoga-in-adolescents-with-dysmenorrhoea-100546749",false,"NCT06398990","The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea","The Effect of Telerehabilitation-Based Cognitive Exercise Therapy Approach and Yoga on Pain, Physical Function and Quality of Life in Adolescents With Dysmenorrhoea","Inclusion Criteria:\n\n* Between the ages of 10 and 19,\n* Having had a menstrual cycle for at least 6-12 months (ACOG, 2018),\n* Having menstrual pain intensity of ≥4 cm according to the Visual Analog Scale (VAS, 0-10 cm) (Kannan, P. 2015; Yonglitthipagon, P. 2017),\n* To have been diagnosed with primary dysmenorrhea according to the clinical characteristics and diagnostic approach defined in international dysmenorrhea guidelines (ACOG 2018; JOGC 2017),\n* Nulliparous (having never given birth),\n* Able to read and write in Turkish,\n* Willing to participate in the study and having provided informed consent.\n\nExclusion Criteria:\n\n* History or clinical findings suggestive of secondary dysmenorrhea,\n* Presence of serious comorbidities, including neurological, cardiovascular, musculoskeletal, psychiatric, gastrointestinal, or autoimmune disorders,\n* History of surgery involving the abdominal, pelvic, or spinal regions within the past 12 months,\n* Current pregnancy or suspected pregnancy,\n* Use of intrauterine devices (IUDs),\n* Having participated in a regular exercise, sports, or physiotherapy program within the last 6 months,\n* Concurrent participation in another clinical study.","FEMALE","10 Years","19 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","Dysmenorrhoea is a condition that negatively affects the quality of life in women of many age groups. In girls with dysmenorrhoea in adolescence, there is an effect on school performance, self-confidence-depression problems and a decrease in quality of life due to pain. In order to eliminate these negative effects, they should receive a good treatment. Medical treatment usually tries to minimise and balance this situation. Considering the fact that families do not want to use drugs such as oral contraceptives in their children at this age and the risks of oral contraceptives, parents are in different searches. Considering that the approach to pain should always be from a holistic perspective, yoga and cognitive exercise therapy approaches are both biopsychosocial treatment methods within the scope of mind-body integrity. Yoga and cognitive exercise therapy approach is thought to reduce symptoms, improve physical functions and quality of life in adolescent girls. With these positive effects, school absenteeism decreases, depression and self-confidence improve. Health costs will also be reduced to some extent.",[28,29],"Dysmenorrhea","Primary Dysmenorrhea",[31,32,33,34],"dysmenorrhea","mind-body exercises","cognitive exercise therapy approach","yoga","RECRUITING","2026-08-19",{"date":38,"type":39},"2026-08-21","ACTUAL",{"date":41,"type":39},"2025-12-01",{"date":43,"type":22},"2026-12",{"name":45,"class":46},"Acibadem University","OTHER",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":47},"100649277","fifa-11-in-young-female-volleyball-players-100649277","NCT07733648","FIFA 11+ in Young Female Volleyball Players","Effects of the FIFA 11+ Exercise Program on Injury Incidence, Fear of Reinjury, and Physical Performance in Young Female Volleyball Players","Inclusion Criteria\n\n* Female volleyball players aged 14-18 years\n* Regular participation in volleyball training for at least 1 year\n* Participation in training sessions at least 2 days per week\n* No history of a serious lower-extremity injury within the previous 6 months\n* Willingness to participate in the study and provision of written informed consent; for participants under 18 years of age, written parental or legal guardian consent will also be obtained\n\nExclusion Criteria\n\n* History of an injury requiring surgery within the previous 6 months\n* Presence of acute pain or injury that prevents safe completion of the physical performance tests\n* Presence of a neurological disorder or systemic disease that may affect balance or physical performance\n* Inability to participate regularly in the FIFA 11+ exercise program\n* Development of an injury during the study period that prevents participation in the exercise program for more than 2 consecutive weeks",true,"14 Years","18 Years",{"count":7,"type":22},[25],"This study aims to investigate the effects of an 8-week FIFA 11+ exercise program on wellness, rating of perceived exertion (RPE), dynamic balance, and single-leg functional performance in young female volleyball players, as well as to examine the relationships among these variables. The study will also evaluate the program's effects on injury incidence and fear of reinjury.\n\nThe study is original in applying the FIFA 11+, a well-established injury prevention program, to volleyball and evaluating its effects together with training-load parameters through a multidimensional approach. It is expected to contribute to the literature by proposing a comprehensive model for monitoring athletic performance and injury risk in young female volleyball players.",[62],"Sport Injuries","NOT_YET_RECRUITING","2026-07-24",{"date":66,"type":39},"2026-07-29",{"date":68,"type":22},"2026-09-10",{"date":70,"type":22},"2027-01-15",{"name":45,"class":46},{"id":73,"slug":74,"hasResults":12,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":55,"sex":80,"minAge":57,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":83,"briefSummary":84,"conditions":85,"keywords":90,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":47},"100648815","effect-of-a-risk-based-perioperative-pressure-injury-prevention-bundle-in-elective-surgery-patients-100648815","NCT07725068","Effect of a Risk-Based Perioperative Pressure Injury Prevention Bundle in Elective Surgery Patients","Effect of a Risk-Based Perioperative Pressure Injury Prevention Bundle on Pressure Injury Development in Patients Undergoing Elective Surgery: A Randomized Controlled Trial","RiPPB","Inclusion Criteria:\n\n* Scheduled to undergo elective orthopedic, general, neurosurgical, or urological surgery\n* Anticipated surgical duration greater than 3 hours\n* No pressure injury present preoperatively\n* Willing and able to provide informed consent to participate\n\nExclusion Criteria:\n\n* Existing pressure injury at enrollment\n* Undergoing emergency surgery\n* Known allergy to dressing\u002Fadhesive materials used in the prevention bundle\n* Severe dermatological condition affecting skin integrity\n* Unplanned postoperative intensive care unit admission","ALL",{"count":82,"type":22},138,[25],"This study evaluates whether a risk-based perioperative pressure injury prevention bundle reduces the development of pressure injuries in patients undergoing elective surgery lasting 3 hours or longer.\n\nPressure injuries that develop during and after surgery are a common patient safety problem, especially in older adults and in longer procedures. In this randomized controlled trial, patients will be assigned by chance to either an intervention group or a control group. In the intervention group, each patient's pressure injury risk will be assessed before surgery using the Braden Scale together with additional perioperative risk factors, and patients will then receive one of three prevention bundles matched to their risk level (low, moderate, or high). The high-risk bundle includes prophylactic silicone foam dressings on the sacrum and heels, targeted positioning, and pressure-redistributing support surfaces. The control group will receive standard perioperative care without risk-based bundling, although Braden Scale assessment will still be performed.\n\nSkin assessments will be conducted at four time points: before surgery, in the post-anesthesia care unit, at 2-4 hours after surgery, and at 24 hours after surgery. The main outcome is whether patients develop early signs of pressure injury, including non-blanchable erythema, within the first 24 postoperative hours. The study hypothesizes that patients receiving the risk-based prevention bundle will have a lower incidence of postoperative pressure injury and non-blanchable erythema compared with patients receiving standard care.",[86,87,88,89],"Pressure Ulcer (PU)","Pressure Injury Prevention","Perioperative Care","Braden Scale",[91,92],"Surgical Wound","risk assessment","2026-07-21",{"date":64,"type":39},{"date":96,"type":22},"2026-08-01",{"date":98,"type":22},"2026-12-30",{"name":45,"class":46},{"id":101,"slug":102,"hasResults":12,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":12,"sex":80,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":47},"100647727","turkish-validity-and-reliability-of-the-heat-sensitivity-scale-for-individuals-with-parkinsons-disease-100647727","NCT07710625","\"Turkish Validity and Reliability of the Heat Sensitivity Scale for Individuals With Parkinson's Disease\"","Cross-Cultural Adaptation and Psychometric Evaluation of the Turkish Version of the Heat Sensitivity Scale in Individuals With Parkinson's Disease","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's disease\n* Hoehn and Yahr stage 1-3\n* Age between 40 and 85 years\n* Mini-Mental State Examination score ≥ 24\n* Sufficient cognitive and communication ability to complete the assessments\n* Attendance at the Movement Disorders Outpatient Clinic of the Neurology Department\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Presence of a major psychiatric disorder, such as major depressive disorder or a psychotic disorder\n* Diagnosis of advanced dementia\n* Presence of an uncontrolled systemic chronic disease, such as uncontrolled diabetes mellitus or hypertension\n* Presence of a severe cardiovascular or respiratory condition\n* Presence of an additional orthopedic or neurological condition that may affect assessment performance\n* Severe visual or hearing impairment that may interfere with the assessments\n* Inability to cooperate adequately during the assessments","40 Years","85 Years",{"count":110,"type":22},100,"OBSERVATIONAL","The aim of this study is to examine the validity and reliability of the Turkish version of the Heat Sensitivity Scale in individuals with Parkinson's disease. This cross-sectional methodological study will evaluate the psychometric properties of the scale, including internal consistency, test-retest reliability, and construct validity, in order to provide a valid and reliable tool for assessing temperature sensitivity in Turkish-speaking individuals with Parkinson's disease.",[114,115],"Parkinson Disease","Temperature Sensivity",{"date":117,"type":39},"2026-07-22",{"date":119,"type":39},"2026-05-25",{"date":121,"type":22},"2027-05-25",{"name":45,"class":46},{"id":124,"slug":125,"hasResults":12,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":55,"sex":80,"minAge":57,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":133,"conditions":134,"keywords":139,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":47},"100648506","factors-affecting-burnout-in-physiotherapists-in-turkey-100648506","NCT07722858","Factors Affecting Burnout in Physiotherapists in Turkey","Examination of Factors Affecting Burnout in Physiotherapists in Turkey: A Hierarchical Regression Analysis","PT-BURNOUT-TR","Inclusion Criteria:\n\n* Licensed physiotherapist in Turkey\n* Currently working in active clinical practice\n* Provides electronic informed consent\n\nExclusion Criteria:\n\n* Not currently working in clinical practice\n* Incomplete questionnaire, defined as responding to less than 50 percent of the COPSOQ III items",{"count":132,"type":22},400,"This cross-sectional descriptive study aims to identify the demographic, occupational, organisational and individual psychological factors that predict burnout among physiotherapists working in active clinical practice in Turkey. Using a four-block hierarchical multiple regression approach, the relative contribution of workload and role factors, organisational factors, psychological resilience, self-efficacy and Type A behaviour pattern to the three dimensions of burnout (emotional exhaustion, depersonalisation and personal accomplishment) will be quantified. Turnover intention is examined as a secondary dependent variable. Data are collected through an anonymous online survey distributed nationwide.",[135,136,137,138],"Burnout, Professional","Occupational Stress","Psychological Resilience","Self Efficacy",[140,141,142,143,144,145,146,147,148,149],"Burnout","Physiotherapists","Physical therapy","Occupational health","Psychosocial work environment","Resilience","Self-efficacy","Type A behaviour pattern","Turnover intention","Hierarchical regression","2026-07-20",{"date":152,"type":39},"2026-07-23",{"date":154,"type":22},"2026-07",{"date":156,"type":22},"2027-01",{"name":45,"class":46},{"id":159,"slug":160,"hasResults":12,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":12,"sex":80,"minAge":57,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":168,"conditions":169,"keywords":175,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":183,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":47},"100648460","illness-perception-and-treatment-expectations-in-lateral-elbow-pain-100648460","NCT07722845","Illness Perception and Treatment Expectations in Lateral Elbow Pain","Determining the Predictors of Illness Perception and Treatment Expectations in Individuals With Lateral Elbow Pain: A Cross-Sectional Study","LEP-IPTE","Inclusion Criteria:\n\n* Aged 18 years or older\n* Diagnosis of lateral epicondylalgia or lateral elbow pain made by an orthopaedic surgeon or physiatrist\n* Pain intensity of at least 4 on the Numeric Rating Scale\n* Pain duration of at least 12 weeks (chronic)\n* Willing to provide written informed consent\n\nExclusion Criteria:\n\n* History of any surgical procedure of the upper extremity\n* Cervical spine pathology\n* Inflammatory arthritis affecting the wrist or finger joints (e.g. rheumatoid arthritis)\n* Active neurological disease or radiculopathy radiating to the upper extremity\n* Diagnosis of fibromyalgia or another widespread pain syndrome\n* Currently receiving active psychiatric treatment (e.g. psychosis, severe depression)\n* Pregnancy\n* Visual or cognitive impairment of a degree that would prevent completion of the questionnaires",{"count":167,"type":22},137,"This cross-sectional, correlational study aims to determine the predictors of illness perception and treatment expectations in adults with chronic lateral elbow pain. Sociodemographic characteristics, clinical findings (pain intensity, pain duration, elbow-specific function) and psychosocial variables (pain self-efficacy, fear-avoidance beliefs, pain catastrophizing) will be examined as candidate predictors of two patient-centred constructs: illness perception, measured with the Brief Illness Perception Questionnaire, and treatment expectation, measured with the Treatment Expectation Questionnaire. Data will be analysed using hierarchical multiple linear regression in three predictor blocks. The study is reported according to the STROBE statement.",[170,171,172,173,174],"Lateral Elbow Pain","Lateral Epicondylitis","Tennis Elbow","Chronic Musculoskeletal Pain","Tendinopathy",[176,177,178,179,180,181,182,149],"Illness perception","Treatment expectation","Lateral epicondylalgia","Pain catastrophizing","Fear-avoidance beliefs","Pain self-efficacy","Biopsychosocial model",{"date":152,"type":39},{"date":185,"type":22},"2026-07-31",{"date":187,"type":22},"2027-01-05",{"name":45,"class":46},{"id":190,"slug":191,"hasResults":12,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":12,"sex":80,"minAge":107,"maxAge":108,"enrollmentInfo":196,"targetDuration":197,"studyType":111,"phases":4,"briefSummary":198,"conditions":199,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":201,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":207,"locationsCount":47},"100630492","turkish-cognitive-self-efficacy-questionnaire-in-parkinsons-disease-100630492","NCT07488377","Turkish Cognitive Self-Efficacy Questionnaire in Parkinson's Disease","Validity and Reliability of the Turkish Version of the Cognitive Self-Efficacy Questionnaire in Individuals With Parkinson's Disease","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's disease\n* Hoehn and Yahr stage 1-3\n* Age 40 to 85 years\n* Mini-Mental State Examination (MMSE) score ≥24\n* Able to communicate and complete study assessments\n* Attending the Movement Disorders Outpatient Clinic, Department of Neurology, Istanbul Cerrahpaşa Faculty of Medicine Hospital\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Major depressive disorder or psychotic disorder\n* Advanced dementia\n* Severe visual impairment that may interfere with study assessments\n* Severe hearing impairment that may interfere with study assessments\n* Inability to cooperate with the physiotherapist\n* Inability to complete the study assessments",{"count":110,"type":22},"2 Months","This study aims to evaluate the validity and reliability of the Turkish version of the Cognitive Self-Efficacy Questionnaire in individuals with Parkinson's disease.",[114],"2026-07-14",{"date":202,"type":39},"2026-07-15",{"date":204,"type":39},"2026-04-01",{"date":206,"type":22},"2027-04-01",{"name":45,"class":46},{"id":209,"slug":210,"hasResults":12,"nctId":211,"briefTitle":212,"officialTitle":213,"acronym":4,"eligibilityCriteria":214,"healthyVolunteers":12,"sex":80,"minAge":107,"maxAge":108,"enrollmentInfo":215,"targetDuration":216,"studyType":111,"phases":4,"briefSummary":217,"conditions":218,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":219,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":47},"100630491","determinants-of-physical-frailty-in-parkinsons-disease-a-multi-factorial-analysis-100630491","NCT07488364","Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis","Investigation of the Relationship Between Motor Imagery, Body Awareness, Kinesiophobia, Physical Activity, Symptom Severity, and Physical Frailty in Patients With Parkinson's Disease","Inclusion Criteria:\n\n* Clinically diagnosed Parkinson's disease\n* Hoehn and Yahr stage 1-3\n* Age 40 to 85 years\n* Mini-Mental State Examination (MMSE) score ≥24\n* Attending the Movement Disorders Outpatient Clinic, Department of Neurology\n* Able to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Major depressive disorder or psychotic disorder\n* Advanced dementia\n* Severe cardiovascular or respiratory disease\n* Uncontrolled chronic systemic disease (e.g., diabetes mellitus or hypertension)\n* Additional neurological or orthopedic conditions that may affect assessment performance\n* Severe visual or hearing impairment that could interfere with study assessments\n* Inability to cooperate with the physiotherapist during study assessments",{"count":110,"type":22},"1 Day","The aim of this study is to examine the associations between motor imagery capacity, body awareness (interoceptive awareness), kinesiophobia, physical activity level, and symptom severity in individuals with Parkinson's disease. In addition, the study aims to evaluate the relationships between these variables and physical frailty. This cross-sectional observational study will provide insight into the biopsychosocial factors associated with frailty in Parkinson's disease.",[114],{"date":202,"type":39},{"date":221,"type":39},"2026-03-30",{"date":223,"type":22},"2027-03-30",{"name":45,"class":46},{"id":226,"slug":227,"hasResults":12,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":4,"eligibilityCriteria":231,"healthyVolunteers":12,"sex":80,"minAge":107,"maxAge":108,"enrollmentInfo":232,"targetDuration":216,"studyType":111,"phases":4,"briefSummary":233,"conditions":234,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":236,"startDateStruct":237,"completionDateStruct":238,"leadSponsor":239,"locationsCount":47},"100630490","self-compassion-and-self-efficacy-in-parkinsons-disease-associations-with-symptoms-function-and-quality-of-life-100630490","NCT07488351","\"Self-Compassion and Self-Efficacy in Parkinson's Disease: Associations With Symptoms, Function, and Quality of Life\"","\"Associations of Self-Compassion and Self-Efficacy With Symptom Severity, Functional Status, and Quality of Life in Individuals With Parkinson's Disease: A Cross-Sectional Study\"","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's disease\n* Hoehn and Yahr stage 1-3\n* Age 40 to 85 years\n* Mini-Mental State Examination (MMSE) score ≥24\n* Sufficient cognitive function to communicate and complete study assessments\n* Attending the Movement Disorders Outpatient Clinic, Department of Neurology\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Major depressive disorder or psychotic disorder\n* Advanced dementia\n* Uncontrolled chronic systemic disease (e.g., diabetes mellitus or hypertension)\n* Severe cardiovascular or respiratory disease\n* Additional neurological or orthopedic conditions that may affect assessment performance\n* Severe visual or hearing impairment that could interfere with study assessments\n* Inability to cooperate with the physiotherapist during study assessments",{"count":110,"type":22},"The aim of this study is to evaluate the associations of self-compassion and self-efficacy levels with symptom severity, functional status, and quality of life in individuals with Parkinson's disease.",[114,235],"Physical Disability",{"date":202,"type":39},{"date":221,"type":39},{"date":223,"type":22},{"name":45,"class":46},{"id":241,"slug":242,"hasResults":12,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":12,"sex":80,"minAge":247,"maxAge":248,"enrollmentInfo":249,"targetDuration":4,"studyType":23,"phases":251,"briefSummary":252,"conditions":253,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":255,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":47},"100629991","the-effect-of-early-phase-graded-motor-imagery-following-massive-rotator-cuff-repair-100629991","NCT07481864","The Effect of Early-Phase Graded Motor Imagery Following Massive Rotator Cuff Repair.","The Effect of Early-Phase Graded Motor Imagery Following Massive Rotator Cuff Repair","Inclusion Criteria:\n\n* Age between 30 and 65 years\n* Presence of an arthroscopically repaired anterior-superior rotator cuff tear, involving the supraspinatus and subscapularis tendons\n\nExclusion Criteria:\n\n* Age younger than 30 years or older than 65 years\n\n  * Presence of severe malignant, hematological, endocrine, metabolic, rheumatologic, or gastrointestinal diseases\n  * Diagnosis of glenohumeral osteoarthritis (Kellgren-Lawrence grade III or higher, with radiographic evidence of osteophytes)\n  * Current treatment with cytotoxic agents or systemic corticosteroids\n  * Alcohol dependence, history of substance abuse, or psychological\u002Femotional disorders that may compromise the validity of informed consent\n  * Previous surgery on the ipsilateral shoulder\n  * Multiple tendon tears, such as combined tears involving the supraspinatus together with the infraspinatus or subscapularis tendons","30 Years","65 Years",{"count":250,"type":22},38,[25],"Massive rotator cuff tears are associated with significant pain, functional limitations, and prolonged rehabilitation following surgical repair. In the early postoperative phase, rehabilitation protocols are often limited due to surgical protection requirements, which may delay the restoration of motor control and shoulder function. Graded motor imagery (GMI), a movement representation technique that includes laterality recognition, motor imagery, and mirror therapy, has been shown to modulate cortical processing and improve pain and motor function in various musculoskeletal and neurological conditions. However, its potential role in early postoperative shoulder rehabilitation has not been adequately investigated.",[254],"Shoulder Pain",{"date":202,"type":39},{"date":257,"type":39},"2026-03-15",{"date":259,"type":22},"2026-09-15",{"name":45,"class":46},{"id":262,"slug":263,"hasResults":12,"nctId":264,"briefTitle":265,"officialTitle":266,"acronym":4,"eligibilityCriteria":267,"healthyVolunteers":12,"sex":80,"minAge":57,"maxAge":248,"enrollmentInfo":268,"targetDuration":4,"studyType":23,"phases":270,"briefSummary":271,"conditions":272,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":279,"completionDateStruct":280,"leadSponsor":282,"locationsCount":47},"100646257","type-2-diabetes-mellitus-and-downhill-aerobic-exercise-training-100646257","NCT07693296","Type 2 Diabetes Mellitus and Downhill Aerobic Exercise Training","The Effect of Downhill Walking Training on Functional Capacity, Peripheral Muscle Strength, and Cardiovascular Responses in Individuals With Type 2 Diabetes Mellitus","Inclusion Criteria:\n\n* Have been diagnosed with Type 2 diabetes mellitus according to the American Diabetes Association (ADA) diagnostic criteria\n* Be able to walk independently and be physically capable of walking on a treadmill\n* Have no acute cardiovascular, neurological, or orthopedic conditions that would prevent participation in the exercise program\n* No major changes to antidiabetic or cardiometabolic treatments within the last 3 months\n* To be under regular follow-up and in a stable clinical condition\n* To have been informed about the study and to provide written informed consent\n\nExclusion Criteria:\n\n* Patients with severe peripheral neuropathy or a lack of protective sensation\n* Lower extremity amputation\n* Diabetic foot ulcer or the presence of severe skin lesions that impair walking\n* Proliferative diabetic retinopathy or advanced retinopathy that could pose a risk of complications during exercise\n* Severe diabetic nephropathy (eGFR \\\u003C30 mL\u002Fmin\u002F1.73 m² or macroalbuminuria \\>300 mg\u002Fg)\n* Uncontrolled hypertension (systolic blood pressure \\>200 mmHg and\u002For diastolic blood pressure \\>110 mmHg)\n* Fasting blood glucose level \\>250 mg\u002FdL with signs of ketosis\n* Unstable angina pectoris, a history of myocardial infarction within the past 6 months, or a history of clinically significant severe arrhythmia\n* Advanced heart failure (NYHA Class III-IV)\n* Having a chronic respiratory disease\n* Having participated in a regular exercise, sports, or physical therapy program within the past 6 months",{"count":269,"type":22},34,[25],"The purpose of this study is to compare the effects of an 8-week supervised downhill walking training program, prescribed based on the 6-minute walk test, on functional capacity, peripheral muscle strength, and cardiovascular responses in individuals with type 2 diabetes mellitus, as compared to a level walking training program.\n\nParticipants who agree to take part in the study will be randomly assigned to either the downhill or the level-ground walking group. Both groups will undergo a 6-minute walk test (6MWT) at the beginning of the study, and participants will then undergo an 8-week walking training program-conducted twice a week on a treadmill under the supervision of a physical therapist-in which their walking speed is determined based on their average speed during the 6MWT and gradually increased, with the duration of the sessions also being extended.\n\nParticipants will do the following:\n\n* They will participate in walking training sessions at a center twice a week for 8 weeks, under the supervision of a physical therapist.\n* Once a week for 8 weeks, they will walk the same distance they walked with their supervisor that week as a homework assignment.\n* They will come to the facility where they conducted their exercise sessions for evaluations at the beginning of the program and after the 8th week.",[273,274,275],"Diabete Type 2","Aerobic Exercise","Walking","2026-07-07",{"date":278,"type":39},"2026-07-09",{"date":204,"type":39},{"date":281,"type":22},"2027-06-01",{"name":45,"class":46},{"id":284,"slug":285,"hasResults":12,"nctId":286,"briefTitle":287,"officialTitle":288,"acronym":4,"eligibilityCriteria":289,"healthyVolunteers":55,"sex":80,"minAge":57,"maxAge":290,"enrollmentInfo":291,"targetDuration":4,"studyType":23,"phases":293,"briefSummary":294,"conditions":295,"keywords":298,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":308,"leadSponsor":309,"locationsCount":4},"100642656","eda-based-adaptive-support-in-vr-als-training-100642656","NCT07650019","EDA-Based Adaptive Support in VR ALS Training","Effects of Electrodermal Activity-Based Adaptive Support Systems on Performance in VR-Based Advanced Life Support Training: A Randomized Controlled Study","Inclusion Criteria:\n\n* Being older than 18\n\nExclusion Criteria:\n\n* prior completion of ALS training\n* history of virtual reality (VR)-induced motion sickness\n* medical conditions such as vertigo or the use of medications known to cause vertigo-like symptoms","25 Years",{"count":292,"type":22},72,[25],"This randomized controlled study aims to investigate the effects of an electrodermal activity (EDA)-based adaptive support system on performance during virtual reality (VR)-based advanced life support (ALS) training. Participants' stress levels will be continuously monitored through EDA during the simulation. When stress exceeds a predefined threshold, the adaptive system will automatically activate a support mode that provides additional guidance and time. The performance outcomes of participants receiving adaptive support will be compared with those receiving standard VR training. The study will also examine the role of presence, anxiety, social anxiety, and personality traits in the relationship between stress and performance.",[296,297],"Adaptive Support Condition","Standard Training Condition",[299,300,301,302,303],"virtual reality","adaptive training","stress","Adaptive Life Support Training","electrodermal activity","2026-07-01",{"date":306,"type":39},"2026-07-02",{"date":154,"type":22},{"date":154,"type":22},{"name":45,"class":46},{"id":311,"slug":312,"hasResults":12,"nctId":313,"briefTitle":314,"officialTitle":315,"acronym":4,"eligibilityCriteria":316,"healthyVolunteers":12,"sex":80,"minAge":18,"maxAge":19,"enrollmentInfo":317,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":318,"conditions":319,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":322,"lastUpdatePostDateStruct":323,"startDateStruct":325,"completionDateStruct":326,"leadSponsor":328,"locationsCount":47},"100645027","psychometric-properties-of-the-turkish-version-of-the-staffordshire-adolescent-idiopathic-scoliosis-questionnaire-100645027","NCT07676019","Psychometric Properties of the Turkish Version of the Staffordshire Adolescent Idiopathic Scoliosis Questionnaire","Psychometric Properties of the Turkish Version of the Staffordshire Adolescent Idiopathic Scoliosis Questionnaire (SQAIS)","Inclusion Criteria\n\n* Aged between 10 and 19 years.\n* Diagnosed with Adolescent Idiopathic Scoliosis (AIS) by an orthopedic surgeon or spine specialist.\n* Able to read and understand Turkish.\n\nExclusion Criteria\n\n* Diagnosis of congenital, neuromuscular, or syndromic scoliosis.\n* History of severe neurological, psychiatric, or cognitive disorders.\n* Presence of communication impairments that may interfere with understanding or completing the questionnaires.\n* History of major trauma or spinal surgery within the previous 6 months.",{"count":110,"type":22},"Patient-Reported Outcome Measures (PROMs) have gained increasing importance in scoliosis research in recent years. Although widely used instruments such as the Scoliosis Research Society-22 (SRS-22) include domains related to body image, their primary purpose is to assess overall health-related quality of life and functional outcomes. In contrast, the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis (SQAIS) was specifically developed to provide a more detailed and patient-centered evaluation of body image and perceived deformity in individuals with adolescent idiopathic scoliosis (AIS). However, a Turkish version of the questionnaire with established validity and reliability is not currently available.\n\nTherefore, the aim of the planned master's thesis is to conduct the cultural adaptation of the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis into Turkish and to evaluate its psychometric properties in adolescents with AIS. The study will involve a systematic process of linguistic translation and cross-cultural adaptation. Subsequently, the validity and reliability of the Turkish version will be assessed through analyses of internal consistency, test-retest reliability, construct validity, and criterion validity.\n\nThe findings of this study are expected to provide a valid and reliable instrument for assessing body image and deformity perception among Turkish adolescents with idiopathic scoliosis, thereby contributing an important patient-centered outcome measure to both clinical practice and research.",[320,321],"Scoliosis","Quality of Life","2026-06-24",{"date":324,"type":39},"2026-06-30",{"date":306,"type":22},{"date":327,"type":22},"2027-03-02",{"name":45,"class":46},{"id":330,"slug":331,"hasResults":12,"nctId":332,"briefTitle":333,"officialTitle":334,"acronym":4,"eligibilityCriteria":335,"healthyVolunteers":12,"sex":80,"minAge":57,"maxAge":336,"enrollmentInfo":337,"targetDuration":4,"studyType":23,"phases":339,"briefSummary":340,"conditions":341,"keywords":344,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":355,"lastUpdatePostDateStruct":356,"startDateStruct":358,"completionDateStruct":360,"leadSponsor":362,"locationsCount":47},"100644569","quadriceps-tendon-vs-peroneus-longus-tendon-in-acl-reconstruction-100644569","NCT07671729","Quadriceps Tendon vs Peroneus Longus Tendon in ACL Reconstruction","A Prospective Randomized Clinical Trial Comparing Quadriceps Tendon and Peroneus Longus Tendon Autografts in Anterior Cruciate Ligament Reconstruction: Clinical, Functional, and Gait Analysis Outcomes","Inclusion Criteria:\n\n* Patients diagnosed with anterior cruciate ligament rupture\n* Patients scheduled for primary anterior cruciate ligament reconstruction\n* Age between 18 and 50 years\n* Ability to provide informed consent\n* Willingness to comply with postoperative rehabilitation and follow-up evaluations\n\nExclusion Criteria:\n\n* Previous ligament reconstruction surgery on the affected knee\n* Multi-ligament knee injuries requiring additional ligament reconstruction\n* Severe osteoarthritis of the knee\n* Revision anterior cruciate ligament reconstruction\n* Neuromuscular disorders affecting lower extremity function\n* Active infection\n* Inability to comply with follow-up protocol","50 Years",{"count":338,"type":22},60,[25],"This prospective randomized clinical trial aims to compare quadriceps tendon and peroneus longus tendon autografts in anterior cruciate ligament reconstruction. Patients with anterior cruciate ligament injury undergoing primary reconstruction surgery will be randomly assigned to one of the two graft groups. Clinical examination findings, return-to-sport outcomes, ankle muscle strength, ankle-related functional scores, and gait analysis parameters will be evaluated at 6 months and 12 months postoperatively. The study aims to investigate both knee-related functional outcomes and donor site morbidity associated with graft harvesting techniques.",[342,343],"Anterior Cruciate Ligament Injury","Anterior Cruciate Ligament Rupture",[345,346,347,348,349,350,351,352,353,354],"ACL reconstruction","Anterior cruciate ligament","Quadriceps tendon autograft","Peroneus longus tendon autograft","Gait analysis","Return to sport","Knee stability","Ankle muscle strength","Functional outcomes","Randomized controlled trial","2026-06-23",{"date":357,"type":39},"2026-06-26",{"date":359,"type":39},"2026-05-01",{"date":361,"type":22},"2027-12",{"name":45,"class":46},{"id":364,"slug":365,"hasResults":12,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":4,"eligibilityCriteria":369,"healthyVolunteers":12,"sex":80,"minAge":57,"maxAge":248,"enrollmentInfo":370,"targetDuration":4,"studyType":23,"phases":372,"briefSummary":373,"conditions":374,"keywords":378,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":4},"100639469","effectiveness-of-combined-glp-1gip-dual-agonist-therapy-and-structured-exercise-on-skeletal-muscle-morphology-quality-and-physical-function-in-overweight-and-obese-individuals-100639469","NCT07609160","Effectiveness of Combined GLP-1\u002FGIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals","Effectiveness of Combined GLP-1\u002FGIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals: a Randomized Controlled Trial Protocol","Inclusion Criteria:\n\n* initiation of tirzepatide-based pharmacological treatment as prescribed by an endocrinology and metabolism specialist,\n* body mass index (BMI) ≥27 kg\u002Fm² and the presence of a comorbidity condition or BMI≥30 kg\u002Fm²\n* age between 18 and 65 years\n\nExclusion Criteria:\n\n* diagnosis of type 1 or type 2 diabetes mellitus\n* presence of cerebrovascular, hematological, pulmonary, rheumatological, or neurological disorders\n* current participation in a structured diet or exercise program\n* use of weight-loss medications within the past 12 months\n* history of upper or lower extremity surgery or injury within the past 6 months\n* any contraindication to resistance exercise as determined by the treating physician.",{"count":371,"type":22},108,[25],"This randomized controlled trial aims to investigate the effects of a 24-week home-based progressive resistance exercise program combined with tirzepatide treatment on skeletal muscle mass, muscle quality, and functional capacity in overweight and obese individuals. A total of 108 participants initiating tirzepatide therapy will be randomized to either exercise plus pharmacotherapy or pharmacotherapy alone. The primary outcome is change in thigh muscle thickness and echo intensity assessed by ultrasonography.",[375,376,377],"Obesity","Sarcopenia","Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities",[379,380,381,382],"exercise","physical activity","muscle","physical function","2026-06-03",{"date":385,"type":39},"2026-06-04",{"date":387,"type":22},"2026-11-01",{"date":389,"type":22},"2028-01-01",{"name":45,"class":46},{"id":392,"slug":393,"hasResults":12,"nctId":394,"briefTitle":395,"officialTitle":396,"acronym":397,"eligibilityCriteria":398,"healthyVolunteers":55,"sex":80,"minAge":57,"maxAge":290,"enrollmentInfo":399,"targetDuration":4,"studyType":23,"phases":401,"briefSummary":402,"conditions":403,"keywords":406,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":418,"lastUpdatePostDateStruct":419,"startDateStruct":421,"completionDateStruct":423,"leadSponsor":425,"locationsCount":47},"100633018","acute-effects-of-smartphone-delivered-local-vibration-on-hand-sensorimotor-performance-100633018","NCT07521228","Acute Effects of Smartphone-Delivered Local Vibration on Hand Sensorimotor Performance","Acute Effects of Smartphone-Delivered Local Vibration at Three Frequencies on Hand Grip Strength, Two-Point Discrimination, Pressure Pain Threshold, and Reaction Time in Healthy Young Adults: A Randomized Crossover Study","SmartVib","Inclusion Criteria:\n\n* Healthy university students aged 18-25 years\n* Willing to participate and provide written informed consent\n* Able to attend three separate measurement sessions\n\nExclusion Criteria:\n\n* Surgical intervention on the hand or wrist within the past 6 months\n* Serious upper extremity injury or trauma within the past 6 months\n* Diagnosis of carpal tunnel syndrome or peripheral nerve entrapment\n* Numbness, paresthesia, or sensory impairment in the hand or wrist\n* History of neurological disease (e.g., stroke, multiple sclerosis, peripheral neuropathy)\n* Active pain, infection, open wound, or dermatological condition at the measurement site\n* Reported hypersensitivity or intolerance to vibration\n* Pregnancy",{"count":400,"type":22},20,[25],"This study investigates the acute effects of smartphone-delivered local vibration on hand sensorimotor performance in healthy young adults. Using a custom-developed iPhone application, three vibration frequencies (80 Hz, 150 Hz, and 220 Hz) are applied to the dominant hand in a randomized crossover design with a minimum 48-hour washout between sessions.\n\nThe primary aim is to evaluate frequency-dependent dose-response effects on hand grip strength. Secondary aims include assessment of two-point discrimination (tactile spatial acuity), pressure pain threshold, and hand reaction time before and immediately after each vibration condition.\n\nThe study seeks to generate evidence on optimal application parameters for smartphone vibration as an accessible and portable local vibration source in clinical and educational settings.",[404,405],"Healthy Volunteers","Vibration; Adverse Effect",[407,408,409,410,411,412,413,414,415,416,417],"local vibration","smartphone vibration","haptic feedback","grip strength","two-point discrimination","pressure pain threshold","reaction time","sensorimotor performance","dose-response","crossover","hand function","2026-04-03",{"date":420,"type":39},"2026-04-09",{"date":422,"type":22},"2026-04",{"date":424,"type":22},"2026-11",{"name":45,"class":46},{"id":427,"slug":428,"hasResults":12,"nctId":429,"briefTitle":430,"officialTitle":431,"acronym":432,"eligibilityCriteria":433,"healthyVolunteers":55,"sex":80,"minAge":57,"maxAge":4,"enrollmentInfo":434,"targetDuration":4,"studyType":23,"phases":435,"briefSummary":436,"conditions":437,"keywords":441,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":418,"lastUpdatePostDateStruct":454,"startDateStruct":455,"completionDateStruct":456,"leadSponsor":457,"locationsCount":47},"100633017","evaluation-of-injury-risk-factors-and-effects-of-individualized-exercise-program-in-basketball-and-volleyball-athletes-100633017","NCT07521215","Evaluation of Injury Risk Factors and Effects of Individualized Exercise Program in Basketball and Volleyball Athletes","Evaluation of Injury Risk Factors With Clinical\u002FFunctional Tests and Effects of Individualized Exercise Program in University Basketball and Volleyball Athletes: A Non-Randomized Parallel-Group Study","IRISPORT","Inclusion Criteria:\n\n* Active member of Acibadem University basketball or volleyball team\n* Regular training within the past 6 months\n* Age 18 years or older\n* Willing to participate and provide written informed consent\n* Physical and cognitive capacity to complete test protocols\n\nExclusion Criteria:\n\n* Surgical intervention within the past 6 months\n* Acute musculoskeletal injury within the past 2 weeks (acute sprain\u002Fstrain\u002Fcontusion etc.) that would preclude testing\n* History of vestibular disorder, neurological disease, or systemic condition that may affect balance testing\n* Uncontrolled cardiovascular disease\u002Fhypertension or other medical condition contraindicating exercise\n* Pregnancy or within the first 6 months postpartum (female athletes)\n* Refusal to provide informed consent",{"count":110,"type":22},[25],"This study aims to identify injury risk factors using a clinical\u002Ffunctional test battery in university basketball and volleyball athletes, to develop individualized exercise prescriptions for athletes scoring below established cut-off values on each test, and to evaluate the effects of an 8-week intervention program on test parameters.\n\nAs a secondary aim, all participants will be monitored prospectively over a 6-month season to assess the incidence of injuries and health problems, and to evaluate the contribution of the individualized program to injury-related health outcomes.\n\nThe study consists of four phases: (1) baseline cross-sectional assessment (T0), (2) 8-week individualized exercise intervention for athletes below cut-off thresholds, (3) post-intervention reassessment (T1), and (4) 6-month prospective injury surveillance (T2).",[438,439,440],"Athletic Injuries","Sports Injury Prevention","Musculoskeletal Injury",[442,443,444,445,446,447,448,449,450,451,452,453],"injury prevention","individualized exercise","Y-Balance Test","Hop Test","Limb Symmetry Index","GIRD","CKCUEST","university athletes","basketball","volleyball","functional screening","neuromuscular training",{"date":420,"type":39},{"date":422,"type":22},{"date":424,"type":22},{"name":45,"class":46},{"id":459,"slug":460,"hasResults":12,"nctId":461,"briefTitle":462,"officialTitle":463,"acronym":4,"eligibilityCriteria":464,"healthyVolunteers":12,"sex":80,"minAge":57,"maxAge":248,"enrollmentInfo":465,"targetDuration":4,"studyType":23,"phases":466,"briefSummary":467,"conditions":468,"keywords":470,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":477,"lastUpdatePostDateStruct":478,"startDateStruct":480,"completionDateStruct":482,"leadSponsor":484,"locationsCount":47},"100631980","occlusal-splint-and-exercise-therapy-for-temporomandibular-disorders-100631980","NCT07507734","Occlusal Splint and Exercise Therapy for Temporomandibular Disorders","The Effects of Occlusal Splint and Exercise in Individuals With Temporomandibular Disorders","Inclusion Criteria:\n\n* Clinical and radiological diagnosis of TMD\n* Being between 18-65 years of age\n* Presence of Temporomandibular Joint (TMJ) pain for the last 3 months.\n\nExclusion Criteria:\n\n* Intra-articular or degenerative joint disorders and subluxation requiring immediate treatment,\n* A history of TMJ or cervical region surgery in the last 3 months,\n* A history of treatment from related regions,\n* The presence of rheumatic diseases, including TMJ diseases,\n* TMJ instability or fracture,\n* The presence of perception-cognition disorder,\n* The presence of chronic pain, such as trigeminal neuralgia.",{"count":250,"type":22},[25],"The goal of this clinical trial is to learn if an exercise protocol can improve temporomandibular pain, jaw function and muscle mechanical properties in individuals with Temporomandibular Disorders (TMD). This study focuses on patients who are already receiving occlusal splint therapy.\n\nThe main question it aims to answer is:\n\nHow does the addition of an exercise protocol to occlusal splint therapy affect temporomandibular pain, jaw function and muscle mechanical properties of the masticatory and neck muscles? Researchers will compare the group receiving both occlusal splint therapy and the exercise protocol to a group only occlusal splint therapy to see if the combined approach is more effective.\n\nParticipants will:\n\n* Undergo an initial assessment of the Jaw Functional Limitation Scale-20 (JLFS-20), Craniofacial Pain and Disability Inventory (CF-PDI), Graded Chronic Pain Scale Version 2.0 (GCPS-2.0), jaw range of motion, pain pressure threshold and muscle mechanical properties.\n* Receive occlusal splint therapy as a part of their treatment.\n* Perform a structured exercise protocol (only 1 group)\n* Attend follow up sessions at the 4th week to monitor changes in all initial assessment parameters.",[469],"Temporomandibular Disorders (TMD)",[471,472,473,474,475,476],"temporomandibular disorders","exercise therapy","occlusal splint","muscle mechanical properties","pain","jaw function","2026-03-27",{"date":479,"type":39},"2026-04-02",{"date":481,"type":39},"2025-07-10",{"date":483,"type":22},"2026-07-10",{"name":45,"class":46},{"id":486,"slug":487,"hasResults":12,"nctId":488,"briefTitle":489,"officialTitle":490,"acronym":491,"eligibilityCriteria":492,"healthyVolunteers":12,"sex":80,"minAge":493,"maxAge":494,"enrollmentInfo":495,"targetDuration":497,"studyType":111,"phases":4,"briefSummary":498,"conditions":499,"keywords":502,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":509,"lastUpdatePostDateStruct":510,"startDateStruct":511,"completionDateStruct":513,"leadSponsor":515,"locationsCount":47},"100631025","electrophysiologic-changes-after-extended-360-capsular-release-100631025","NCT07495306","Electrophysiologic Changes After Extended 360° Capsular Release","Electrophysiological Evidence of Neural Function Improvement After Extended Arthroscopic Circumferential Capsular Release for Adhesive Capsulitis","FROZEN-EMG","Inclusion Criteria:\n\n* Age between 21 and 70 years\n* Diagnosis of adhesive capsulitis (frozen shoulder)\n* Persistent symptoms despite conservative treatment (e.g., physical therapy, medication, or intra-articular injections)\n* Planned arthroscopic capsular release surgery\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Known peripheral neuropathy\n* Previous brachial plexus injury\n* History of ipsilateral shoulder neurovascular surgery\n* Previous proximal brachial plexus surgery\n* Coagulation disorders\n* Active infection\n* Pregnancy","21 Years","70 Years",{"count":496,"type":22},15,"12 Weeks","Frozen shoulder (adhesive capsulitis) is a condition characterized by shoulder pain and restricted range of motion, significantly impairing daily living activities. In cases that do not respond to conservative treatment, arthroscopic capsular release is an effective surgical treatment option. The 360° capsular release technique, performed by some surgeons, involves release of the inferior capsule and therefore carries a potential risk of nerve injury due to the anatomical proximity of neurovascular structures such as the axillary nerve. In addition, surgical manipulations performed around the coracoid process may exert mechanical or compressive effects on the musculocutaneous nerve and its sensory continuation, the lateral antebrachial cutaneous nerve, due to their close relationship with the lateral cord of the brachial plexus.\n\nThe aim of this prospective, single-center observational clinical study is to objectively evaluate the morphological and functional effects of inferior capsular release and coracoid region dissection performed during arthroscopic 360° capsular release surgery on the axillary and musculocutaneous nerves, using electromyography (EMG) and nerve conduction studies (NCS) in patients with frozen shoulder.\n\nPatients aged 21-70 years with a diagnosis of frozen shoulder who have not responded to conservative treatments and are scheduled for arthroscopic capsular release will be included in the study. EMG and NCS assessments will be performed at the preoperative baseline, and at 12 weeks postoperatively. For the axillary nerve, the deltoid and teres minor muscles will be evaluated; for the musculocutaneous nerve, the biceps brachii and brachialis muscles will be assessed. Additionally, sensory conduction of the lateral antebrachial cutaneous nerve will be examined. Along with electrophysiological findings, shoulder range of motion (ROM), pain (VAS), muscle strength (MRC), and functional scores will also be recorded.\n\nThis study is expected to provide objective evidence regarding the effects of arthroscopic capsular release surgery on peripheral nerve function, thereby contributing new data on the safety of the surgical technique and enriching the currently limited literature on electromyographic evaluation in frozen shoulder surgery.",[500,501],"Adhesive Capsulitis","Frozen Shoulder",[500,503,504,505,506,507,508],"360° Capsular Release","Shoulder Arthroscopy","Electromyography","Axillary Nerve","Musculocutaneous Nerve","Peripheral Nerve Function","2026-03-23",{"date":477,"type":39},{"date":512,"type":39},"2026-02-26",{"date":514,"type":22},"2027-03-14",{"name":45,"class":46},{"id":517,"slug":518,"hasResults":12,"nctId":519,"briefTitle":520,"officialTitle":520,"acronym":4,"eligibilityCriteria":521,"healthyVolunteers":55,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":522,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":524,"conditions":525,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":509,"lastUpdatePostDateStruct":532,"startDateStruct":534,"completionDateStruct":536,"leadSponsor":538,"locationsCount":47},"100624711","relationship-between-the-severity-of-sleep-deprivation-in-the-first-48-hours-postpartum-breastfeeding-motivation-and-breastfeeding-success-100624711","NCT07413185","Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and Breastfeeding Success","Inclusion Criteria:\n\n* Primiparous or multiparous women aged 18 years and older\n* Having a healthy term delivery\n* Infant not admitted to the neonatal intensive care unit (NICU)\n* Initiated breastfeeding within the first 48 hours postpartum\n\nExclusion Criteria:\n\n* Complications requiring sedation\n* Severe postpartum hemorrhage\n* Severe postoperative pain or need for narcotic analgesics",{"count":523,"type":22},167,"The postpartum period is a critical time marked by significant physiological and psychosocial changes that can affect sleep, emotional well-being, and breastfeeding behaviors. Previous studies indicate that mode of delivery and sleep quality are closely associated with breastfeeding outcomes, with cesarean birth often linked to poorer sleep and lower breastfeeding success. Evidence also suggests that postpartum sleep disturbances are related to reduced breastfeeding self-efficacy, lower motivation, fatigue, depressive symptoms, and shorter breastfeeding duration.\n\nHowever, the literature lacks studies that evaluate insomnia severity, breastfeeding motivation, and breastfeeding success simultaneously-particularly during the first 48 hours after birth. This analytical study aims to assess insomnia severity, breastfeeding motivation, and breastfeeding success (LATCH) within the first 48 postpartum hours and to examine the relationships among these variables. Findings are expected to support early postpartum clinical interventions to improve maternal and infant health outcomes.",[526,527,528,529,530,531],"Postpartum Period","Sleep","Breastfeeding","Motivation","Cesarean Section","Lactation",{"date":533,"type":39},"2026-03-24",{"date":535,"type":39},"2026-03-12",{"date":537,"type":22},"2027-02-23",{"name":45,"class":46},{"id":540,"slug":541,"hasResults":12,"nctId":542,"briefTitle":543,"officialTitle":544,"acronym":4,"eligibilityCriteria":545,"healthyVolunteers":55,"sex":80,"minAge":546,"maxAge":547,"enrollmentInfo":548,"targetDuration":4,"studyType":23,"phases":550,"briefSummary":551,"conditions":552,"keywords":554,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":562,"lastUpdatePostDateStruct":563,"startDateStruct":565,"completionDateStruct":567,"leadSponsor":569,"locationsCount":47},"100616192","effect-of-paternal-touch-on-sucking-performance-comfort-and-glucose-levels-in-newborns-at-risk-for-hypoglycemia-100616192","NCT07302412","Effect of Paternal Touch on Sucking Performance, Comfort, and Glucose Levels in Newborns at Risk for Hypoglycemia","The Effect of Paternal Touch on Sucking Performance, Comfort, and Glucose Levels in Newborns at Risk for Hypoglycemia During the First Hours of Life","Inclusion Criteria:\n\n* Newborns identified as being at risk for hypoglycemia (see study population).\n* Newborns whose parents\u002Flegal guardians have provided written informed consent.\n* Clinically stable newborns who have no contraindications to breastfeeding during the first 6 hours after birth.\n* Newborns whose fathers are present during the first 6 hours after birth.\n\nExclusion Criteria:\n\n* Newborns who develop hypoglycemia during the study period or who require initiation of hypoglycemia treatment.\n* Newborns with congenital anomalies or a diagnosed genetic syndrome.","1 Hour","6 Hours",{"count":549,"type":22},98,[25],"This randomized controlled trial aims to examine the effects of Gentle Human Touch applied by fathers during the first hours of life on sucking performance, comfort level, and blood glucose values in newborns at risk for hypoglycemia. Eligible newborns will be randomly assigned to intervention and control groups.\n\nAfter the newborn is taken to the baby care room and routine care procedures are completed, comfort level will be assessed by the primary nurse and an independent second observer using the Neonatal Comfort and Behavior Scale (NCBS). In the intervention group, the first Gentle Human Touch application will begin after routine care and the initial comfort assessment are completed. Sucking performance will be assessed during the first breastfeeding session by the primary nurse and an independent observer using the LATCH Breastfeeding Assessment Tool.\n\nIn the intervention group, fathers will administer 15-minute Gentle Human Touch sessions every hour for six hours according to a structured protocol. In the control group, routine care will be provided without any additional touch.\n\nIn both the intervention and control groups, blood glucose levels will be measured at the 2nd hour according to clinical protocols. At the 6th hour, the newborn's comfort level (NCBS), sucking performance (LATCH), and blood glucose level will be reassessed and recorded.\n\nThis study aims to determine whether early paternal touch supports glucose stability, improves sucking performance, and enhances comfort in newborns at risk for hypoglycemia, and to contribute to the development of family-centered, non-invasive care practices in neonatal settings.",[553],"Infant, Newborn",[555,556,557,558,559,560,561],"Gentle Human Touch","Paternal Touch","Newborn Feeding Performance","Comfort","Infant,","Blood Glucose","Newborn","2026-03-10",{"date":564,"type":39},"2026-03-11",{"date":566,"type":39},"2026-01-05",{"date":568,"type":22},"2027-12-08",{"name":45,"class":46},{"id":571,"slug":572,"hasResults":12,"nctId":573,"briefTitle":574,"officialTitle":575,"acronym":4,"eligibilityCriteria":576,"healthyVolunteers":55,"sex":80,"minAge":248,"maxAge":4,"enrollmentInfo":577,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":579,"conditions":580,"keywords":586,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":591,"lastUpdatePostDateStruct":592,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":598,"locationsCount":47},"100621397","self-compassion-self-efficacy-and-health-outcomes-in-older-adults-100621397","NCT07370090","Self-Compassion, Self-Efficacy, and Health Outcomes in Older Adults","The Effect of Self-Compassion and Self-Efficacy on Postural Awareness, Pain, and Health-Promoting Lifestyle Behaviors in Older Adults","Inclusion Criteria:\n\n* Aged 65 years and older\n* Able to read and understand Turkish\n* Able to complete online questionnaires independently\n* Provided informed consent\n\nExclusion Criteria:\n\n* Diagnosis of severe cognitive impairment (e.g., dementia or Alzheimer's disease)\n* Severe psychiatric disorders (e.g., schizophrenia or bipolar disorder)\n* Inability to complete questionnaires independently\n* Incomplete or inconsistent questionnaire responses",{"count":578,"type":22},150,"This cross-sectional observational study aims to examine the relationship between self-compassion, self-efficacy, postural awareness, pain, quality of life, and health-promoting lifestyle behaviors in adults aged 65 years and older. Data will be collected using validated self-report questionnaires administered online. The findings are expected to contribute to a better understanding of psychological factors associated with physical and behavioral health outcomes in older adults.",[581,582,583,584,585],"Older Adults (65 Years and Older)","Health Behavior","Self-Compassion","Self-Efficacy","Pain",[587,146,588,589,590,585],"Self-compassion","Older adults","Postural awareness","Health-promoting lifestyle","2026-01-19",{"date":593,"type":39},"2026-01-27",{"date":595,"type":22},"2026-01-15",{"date":597,"type":22},"2026-03-01",{"name":45,"class":46},{"id":600,"slug":601,"hasResults":12,"nctId":602,"briefTitle":603,"officialTitle":603,"acronym":4,"eligibilityCriteria":604,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":605,"enrollmentInfo":606,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":608,"conditions":609,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":613,"lastUpdatePostDateStruct":614,"startDateStruct":616,"completionDateStruct":618,"leadSponsor":620,"locationsCount":47},"100616665","the-relationship-between-quality-of-life-anxiety-levels-and-attitudes-toward-artificial-intelligence-among-women-undergoing-infertility-treatment-100616665","NCT07308561","The Relationship Between Quality of Life, Anxiety Levels, and Attitudes Toward Artificial Intelligence Among Women Undergoing Infertility Treatment","Inclusion Criteria:\n\n* Women aged 18-45 years diagnosed with infertility (primary or secondary infertility).\n* Women undergoing infertility treatment and those who have experienced various treatment modalities (IUI, IVF, ICSI).\n* Women who voluntarily agree to participate in the study.\n* Women who are able to understand and speak Turkish.\n\nExclusion Criteria:\n\n* Women with diagnosed psychological disorders (e.g., clinical depression, anxiety disorders).\n* Women who are not undergoing infertility treatment.","45 Years",{"count":607,"type":22},191,"Infertility affects approximately one in six individuals worldwide and is associated with significant psychological distress, particularly among women undergoing treatment. Increased anxiety levels are strongly linked to reduced quality of life during the infertility process. With the growing integration of artificial intelligence (AI) into healthcare, AI-based tools are increasingly used in infertility care to support decision-making and patient engagement. While many patients are familiar with AI technologies, individual attitudes toward AI may influence their acceptance and potential psychosocial benefits. This study aims to examine the relationship between attitudes toward artificial intelligence, anxiety levels, and quality of life among women undergoing infertility treatment.",[610,611,321,612],"Infertility, Female","Artificial Intelligence","Anxiety","2025-12-17",{"date":615,"type":39},"2025-12-29",{"date":617,"type":39},"2025-10-23",{"date":619,"type":22},"2026-10-23",{"name":45,"class":46},{"id":622,"slug":623,"hasResults":12,"nctId":624,"briefTitle":625,"officialTitle":626,"acronym":4,"eligibilityCriteria":627,"healthyVolunteers":55,"sex":80,"minAge":628,"maxAge":629,"enrollmentInfo":630,"targetDuration":4,"studyType":23,"phases":632,"briefSummary":633,"conditions":634,"keywords":638,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":643,"lastUpdatePostDateStruct":644,"startDateStruct":646,"completionDateStruct":648,"leadSponsor":650,"locationsCount":47},"100613951","feeding-maturity-in-preterm-infants-100613951","NCT07273266","Feeding Maturity in Preterm Infants","The Effect of Routine Versus Random Pacifier Administration Methods on Feeding Maturity in Preterm Infants","Inclusion Criteria:\n\n* Preterm\n* who are clinically stable, and\n* who are within the first day of initiating enteral feeding.\n\nExclusion Criteria:\n\n* Newborns who have a contraindication to pacifier use\n* have comorbid medical conditions\n* who are intubated\n* have congenital anomalies","0 Days","28 Days",{"count":631,"type":22},62,[25],"The aim of this study is to evaluate the effect of two pacifier-use strategies-routine 5-minute pacifier use prior to each feeding versus random 30-minute pacifier use at any time of day, independent of feeding-on feeding maturity in preterm infants. The hypotheses of the study are as follows: H1: The routine use of a pacifier prior to feeding has a positive effect on feeding maturity in preterm infants.\n\nH2: The routine use of a pacifier prior to feeding has a positive effect on discharge weight in preterm infants.\n\nH3: The routine use of a pacifier prior to feeding has a positive effect on the length of hospital stay in preterm infants.\n\nH4: The routine use of a pacifier prior to feeding has a positive effect on the gestational age at discharge in preterm infants.",[635,636,637],"Preterm","Feeding","Non Nutritive Sucking",[639,640,641,642],"preterm","feeding","non nutritive sucking","feeding maturation","2025-12-07",{"date":645,"type":39},"2025-12-09",{"date":647,"type":39},"2025-03-04",{"date":649,"type":22},"2026-07-30",{"name":45,"class":46},{"id":652,"slug":653,"hasResults":12,"nctId":654,"briefTitle":655,"officialTitle":656,"acronym":657,"eligibilityCriteria":658,"healthyVolunteers":55,"sex":80,"minAge":57,"maxAge":248,"enrollmentInfo":659,"targetDuration":4,"studyType":23,"phases":661,"briefSummary":662,"conditions":663,"keywords":667,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":671,"lastUpdatePostDateStruct":672,"startDateStruct":674,"completionDateStruct":676,"leadSponsor":678,"locationsCount":679},"100613612","effect-of-fan-application-in-preventing-ticagrelor-associated-dyspnea-100613612","NCT07268859","Effect of Fan Application in Preventing Ticagrelor-Associated Dyspnea","Effect of Fan Application in Preventing Ticagrelor-associated Dyspnea in Patients With Acute Coronary Syndrome.","ACS","Inclusion Criteria:\n\n* Between the ages of 18 and 65,\n* No severe hearing and vision problems,\n* Can speak and understand Turkish,\n* Easy to communicate with,\n* First-time sufferer of acute coronary syndrome (ACS) for the first time,\n* Decided to start ticagrelor therapy,\n* Able to adapt to treatment,\n* Individuals who volunteered to participate in the research.\n\nExclusion Criteria:\n\n* Having any problem that prevents you from communicating cognitively, emotionally and verbally,\n* Obstructive sleep abnormalities,\n* Have a disease that affects respiratory function (stage IV cancer, bronchial asthma, COVID-19, lung cancer, pulmonary edema, chronic obstructive pulmonary disease, pulmonary hypertension, pulmonary embolism, pneumonia or bronchitis, etc.),\n* With metabolic abnormalities,\n* Intubated after the procedure,\n* Previously treated with ticagrelor,\n* Individuals who did not volunteer to participate in the study. Losses to follow up\n* Individuals who wish to leave the study voluntarily.\n* Saturation value below 95%,\n* The one with the arrest,\n* Who will not be able to fulfill the requirements of the work,\n* Individuals with life-threatening conditions",{"count":660,"type":22},110,[25],"This study will be conducted in the coronary intensive care unit of Dr. Siyami Ersek Chest, Heart and Vascular Surgery Training and Research Hospital. It aims to investigate the effect of hand fan therapy on ticagrelor-associated dyspnea in patients receiving ticagrelor.",[664,665,666],"Acute Coronary Syndromes","Ticagrelor","Dyspnea",[668,665,669,666,670],"Nursing","Hand fan therapy","Non-pharmacological intervention","2025-12-04",{"date":673,"type":39},"2025-12-08",{"date":675,"type":39},"2025-03-15",{"date":677,"type":22},"2026-01-30",{"name":45,"class":46},2,""]