[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Akdeniz University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":121},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,64,95],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":20,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100648588","assessment-of-hemodynamic-responses-at-adequate-depth-of-anesthesia-using-bispectral-index-during-rapid-sequence-intubation-in-the-emergency-department-100648588",false,"NCT07722897","Assessment of Hemodynamic Responses at Adequate Depth of Anesthesia Using Bispectral Index During Rapid Sequence Intubation in the Emergency Department","Inclusion Criteria:\n\nAdults aged 18 years or older. Patients undergoing rapid sequence intubation (RSI) in the emergency department.\n\nPatients in whom bispectral index (BIS) monitoring can be applied before laryngoscopy.\n\nPatients achieving an adequate depth of anesthesia (BIS 45-55) before laryngoscopy.\n\nWritten informed consent obtained from the patient or a legally authorized representative, when applicable according to local ethics requirements.\n\nExclusion Criteria:\n\nAge \\\u003C18 years. Cardiac arrest before or during induction. Patients requiring immediate (\"crash\") intubation without sufficient time for BIS monitoring.\n\nInability to obtain reliable BIS monitoring (e.g., technical failure or inability to place the sensor).\n\nPregnancy. Facial or scalp conditions preventing BIS sensor placement. Prisoners or other vulnerable populations if excluded by the ethics protocol.\n\n\\-","ALL","18 Years",{"count":18,"type":19},200,"ESTIMATED","1 Day","OBSERVATIONAL","Rapid sequence intubation (RSI) is the standard approach for emergency airway management in critically ill patients requiring endotracheal intubation. Laryngoscopy and tracheal intubation may provoke significant hemodynamic responses, including increases in heart rate and blood pressure, which may adversely affect patients with severe neurological or cardiovascular disease.\n\nAlthough hemodynamic responses during tracheal intubation have been extensively investigated in the anesthesiology literature, evidence from emergency department settings remains limited. Furthermore, previous studies have rarely confirmed whether an adequate depth of anesthesia had been achieved before laryngoscopy, making interpretation of hemodynamic responses difficult.\n\nThe aim of this prospective observational study is to evaluate hemodynamic responses during rapid sequence intubation in adult emergency department patients after confirming adequate depth of anesthesia using bispectral index (BIS) monitoring. Heart rate and blood pressure will be recorded before induction, during intubation, and after successful endotracheal intubation, allowing objective assessment of the hemodynamic response under confirmed adequate anesthetic depth.",[24],"Critical Illness",[26,27,28,29],"Rapid Sequence Intubation","Emergency Department","Bispectral Index","Hemodynamic Response","RECRUITING","2026-07-20",{"date":33,"type":34},"2026-07-23","ACTUAL",{"date":36,"type":34},"2026-05-01",{"date":38,"type":19},"2028-05-01",{"name":40,"class":41},"Akdeniz University Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":61,"leadSponsor":63,"locationsCount":42},"100646482","bispectral-index-and-first-pass-intubation-100646482","NCT07690254","Bispectral Index and First-Pass Intubation","Evaluation of First-Pass Endotracheal Intubation Success Using the Bispectral Index in Patients Undergoing Endotracheal Intubation in the Emergency Department","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Patients undergoing rapid sequence intubation (RSI) in the emergency department\n* No traumatic injury to the frontal region that would interfere with placement of the Bispectral Index (BIS) sensor\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Pregnant patients\n* Patients with cardiac arrest or hemodynamic instability at the time of enrollment\n* Patients intubated without the rapid sequence intubation (RSI) protocol\n* Refusal to participate in the study (by the patient or, where applicable, a legally authorized representative)",{"count":51,"type":19},150,"This prospective observational study aims to evaluate the association between anesthetic depth, measured by the Bispectral Index (BIS), and first-pass endotracheal intubation success in adult patients undergoing rapid sequence intubation (RSI) in the emergency department.\n\nEndotracheal intubation is one of the most critical procedures performed in emergency medicine. Multiple intubation attempts are associated with an increased risk of adverse events, including hypoxemia, aspiration, cardiovascular complications, and death. Although several factors influence first-pass intubation success, the contribution of anesthetic depth at the time of intubation has not been adequately investigated in the emergency department.\n\nPatients for whom the treating emergency physician decides to perform RSI will undergo noninvasive BIS monitoring using a disposable forehead sensor. The physician performing the intubation will remain blinded to the BIS value throughout the procedure and will perform intubation according to routine clinical practice. A separate investigator, who is not involved in patient management, will record the BIS value at the time of intubation.\n\nThe BIS measurements will not be disclosed to the treating team and will not influence clinical decision-making, medication dosing, or patient management. The study is purely observational and does not evaluate the performance or effectiveness of the BIS device itself.\n\nThe primary objective is to determine whether patients who achieve first-pass intubation success differ in anesthetic depth from those requiring multiple intubation attempts.",[54],"Emergency Airway Management",[26,56,28],"First-Pass Success","2026-07-02",{"date":59,"type":34},"2026-07-08",{"date":36,"type":34},{"date":62,"type":19},"2028-05",{"name":40,"class":41},{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":42},"100627971","postoperative-pain-monitoring-with-ani-in-lumbar-spine-surgery-100627971","NCT07455565","Postoperative Pain Monitoring With ANI in Lumbar Spine Surgery","Comparison Of Postoperative Analgesic Efficacy Using Analgesia Nociception Index Monitoring In Patients Undergoing Elective Lumbar Spine Surgery: A Randomized Parallel-Group Study","SPINE-ANI","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* ASA physical status I-II\n* Scheduled for elective lumbar spine surgery\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Known allergy to study medications\n* Coagulation disorders\n* Infection at the block site\n* Severe cardiovascular disease\n* Pregnancy\n* Inability to understand the study protocol","65 Years",{"count":74,"type":19},100,"INTERVENTIONAL",[77],"NA","This study aims to compare two different pain management methods in patients undergoing elective lumbar spine surgery. Patients are randomly assigned to receive either an ultrasound-guided erector spinae plane block (ESPB) or intravenous multimodal analgesia.\n\nPostoperative pain will be assessed using both clinical pain scores and the Analgesia Nociception Index (ANI), a non-invasive monitoring system that evaluates pain-related responses based on heart rate variability. The goal of this study is to determine which method provides better postoperative pain control.",[80,81],"Postoperative Pain","Lumbar Spine Surgery",[83,84,80,81,85,86],"Analgesia Nociception Index","Erector Spinae Plane Block","Multimodal Analgesia","Randomized Controlled Trial","2026-03-03",{"date":89,"type":34},"2026-03-06",{"date":91,"type":34},"2025-12-16",{"date":93,"type":19},"2026-12",{"name":40,"class":41},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":102,"minAge":4,"maxAge":4,"enrollmentInfo":103,"targetDuration":4,"studyType":75,"phases":105,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":112,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":4},"100599668","effects-of-a-nurse-led-transition-to-fatherhood-program-on-fathers-involvement-in-infant-care-gender-perception-and-father-infant-bonding-100599668","NCT07087483","Effects of a Nurse-Led Transition to Fatherhood Program on Fathers' Involvement in Infant Care, Gender Perception, and Father-Infant Bonding","Effects of a Nurse-Led Transition to Fatherhood Program on Fathers' Involvement in Infant Care, Gender Perception, and Father-Infant Bonding: A Randomized Controlled Trial","Inclusion Criteria:\n\n* being a newborn father\n\nExclusion Criteria:\n\n* N\u002FA","MALE",{"count":104,"type":19},80,[77],"Fatherhood transition programs led by nurses can positively influence fathers' involvement in infant care, gender roles, and father-infant bonding. These programs encourage fathers to take a more active role in both the prenatal and postnatal periods, enhancing their knowledge and skills related to infant care. Through these programs, fathers gain more information and practical abilities in caring for their babies.\n\nThe trainings provided by nurses cover essential care topics such as infant and maternal nutrition, sleep routines, diapering, burping, hygiene, and safety. This knowledge enables fathers to participate in infant care more effectively and safely.\n\nTraditional gender roles often assume that infant care is primarily the mother's responsibility. However, nurse-led programs emphasize that fathers can and should take an active role in this process. This helps break down stereotypes related to gender roles and strengthens the father's role in childcare.\n\nActive participation in infant care from an early stage contributes to the development of a strong emotional bond between father and baby. Quality time spent together, physical contact, and shared activities reinforce this bond. Research shows that a strong father-infant bond has positive effects on a child's emotional and social development.\n\nIn conclusion, nurse-led fatherhood transition programs significantly contribute to reshaping traditional gender roles and strengthening the emotional bond between fathers and their babies by increasing paternal involvement in infant care. Expanding such programs can lead to long-term positive outcomes for both fathers and children.",[108,109],"Training Effectiveness","Fatherhood Transition Training for New Fathers",[111],"fathers","NOT_YET_RECRUITING","2025-07-18",{"date":115,"type":34},"2025-07-28",{"date":117,"type":19},"2025-08-30",{"date":119,"type":19},"2025-11-30",{"name":40,"class":41},""]