[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Antalya Health Sciences University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":221},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,44,65,93,116,142,169,195],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100651887","clinical-characteristics-and-in-hospital-outcomes-of-critically-ill-patients-receiving-hemodialysis-or-continuous-venovenous-hemodiafiltration-in-the-emergency-department-100651887",false,"NCT07765030","Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department","Evaluation of Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Undergoing Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department","Inclusion Criteria:\n\n* Age 18 years or older.\n* Followed in the critical care area of the Emergency Department of Antalya\n* Training and Research Hospital between January 1, 2023, and August 1, 2026.\n* Presence of an indication for emergency renal replacement therapy.\n* Underwent hemodialysis (HD) or continuous venovenous hemodiafiltration (CVVHDF) in the emergency department.\n* Required critical care-level monitoring or management.\n* Availability of sufficient demographic, clinical, laboratory, and in-hospital outcome data in the hospital information system, electronic medical records, laboratory records, or clinical follow-up notes.\n\nExclusion Criteria:\n\n* Age younger than 18 years.\n* Renal replacement therapy initiated outside the emergency department.\n* Presentation only for routine chronic hemodialysis at the hospital dialysis unit without receiving renal replacement therapy in the emergency department.\n* Renal replacement therapy planned in the emergency department but HD or CVVHDF could not be performed.\n* Missing essential clinical, laboratory, or in-hospital outcome data. In patients with repeated emergency department admissions, only the first emergency renal replacement therapy episode will be included to reduce statistical dependency.","ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","This retrospective observational study aims to evaluate the clinical characteristics and in-hospital outcomes of critically ill adult patients who underwent hemodialysis (HD) or continuous venovenous hemodiafiltration (CVVHDF) in the Emergency Department of Antalya Training and Research Hospital between January 1, 2023, and August 1, 2026.\n\nMedical records will be reviewed to collect information on patient demographics, comorbidities, clinical findings at admission, vital signs, renal replacement therapy indications, laboratory results before and after treatment, treatment modality, treatment-related complications, need for intubation or vasopressor\u002Finotropic support, intensive care unit admission, length of stay, and hospital outcomes.\n\nThe primary outcome is in-hospital mortality. Secondary outcomes include emergency department mortality, intensive care unit admission, ward admission, discharge status, emergency department and hospital length of stay, need for intubation or vasopressor\u002Finotropic support, treatment completion, treatment-related complications, and changes in laboratory parameters before and after renal replacement therapy. No additional intervention, test, treatment, or biological sample collection will be performed as part of this study.",[24,25,26],"Acute Kidney Injury","Kidney Failure, Acute","Kidney Failure",[28,29,30,24,31],"Emergency Renal Replacement Therapy","Hemodialysis","Continuous Venovenous Hemodiafiltration","In-Hospital Mortality","NOT_YET_RECRUITING","2026-08-10",{"date":35,"type":36},"2026-08-14","ACTUAL",{"date":33,"type":20},{"date":39,"type":20},"2026-11-01",{"name":41,"class":42},"Antalya Health Sciences University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":52,"studyType":21,"phases":4,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":59,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":43},"100651802","development-and-validation-of-an-ultrasound-based-difficult-cannulation-risk-score-for-pre-procedural-internal-jugular-vein-catheterization-in-critically-ill-patients-a-prospective-observational-cohort-study-100651802","NCT07764562","Development and Validation of an Ultrasound-Based Difficult Cannulation Risk Score for Pre-procedural Internal Jugular Vein Catheterization in Critically Ill Patients: A Prospective Observational Cohort Study","ROTATE-ICU","Inclusion Criteria:\n\nAge ≥18 years. Admission to the intensive care unit. Clinical indication for central venous catheterization. Planned internal jugular vein access. Planned ultrasound-guided catheterization. Written informed consent obtained from the participant or legally authorized representative, where required.\n\nExclusion Criteria:\n\nActive cardiopulmonary resuscitation at the time of catheterization. Neck anatomical abnormality preventing standard IJV assessment or catheterization.\n\nNeck hematoma. Active local soft-tissue infection at the proposed access site. Planned vascular access through a site other than the internal jugular vein. Planned catheterization without ultrasound guidance. Refusal or inability to obtain required informed consent.",{"count":19,"type":20},"15 Days","Ultrasound-guided internal jugular vein (IJV) catheterization is widely used in critically ill patients. Despite ultrasound guidance, difficult catheterization and first-pass failure remain clinically important and may increase the risk of mechanical complications. Pre-procedural characteristics of the IJV, its anatomical relationship with the common carotid artery (CCA), head rotation, and operator experience may influence procedural success.\n\nThe ROTATE-ICU study is a prospective observational cohort study designed to investigate pre-procedural ultrasound and clinical predictors of difficult IJV catheterization in critically ill adults. Consecutive adult intensive care unit patients undergoing ultrasound-guided IJV central venous catheterization will undergo standardized pre-procedural ultrasound assessment. IJV anterior-posterior diameter, skin-to-vessel depth, IJV position relative to the CCA, head rotation angle, operator experience, and relevant clinical and procedural characteristics will be recorded.\n\nThe primary objective is to develop and internally validate a clinical prediction model for cannulation difficulty and first-pass cannulation outcome. Secondary objectives include evaluating the relationship between head rotation and IJV morphology and describing the association between complete IJV collapse and procedural outcomes. The planned enrollment is 150 participants.",[55],"Adult Critically Ill Patients Who Require Ultrasound-guided Internal Jugular Vein Central Venous Catheterization",[57],"Internal jugular vein; Central venous catheterization; Ultrasound guidance; First-pass success; Critical care; Prediction model.","RECRUITING",{"date":35,"type":36},{"date":61,"type":36},"2026-06-26",{"date":63,"type":20},"2026-09-26",{"name":41,"class":42},{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":76,"conditions":77,"keywords":81,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":43},"100641629","bispectral-index-in-patients-undergoing-vertebral-surgery-using-artificial-intelligence-programs-a-methodological-study-100641629","NCT07650604","Bispectral Index in Patients Undergoing Vertebral Surgery Using Artificial Intelligence Programs: A Methodological Study","INTERPRETATION AND EVULATION OF THE PROXIMITY TO CLINICAL EXPERIENCE OF BISPECTRAL INDEX (BIS) IN PATIENTS UNDERGOİNG VERTEBRAL SURGERY USING ARTIFICIAL INTELLIGENCE PROGRAMS: A METHODOLOGICAL STUDY","BIS","Inclusion Criteria:\n\n* elective vertebra surgery\n* aged 18-65\n* ASA score I-III\n* BMI \\\u003C30 kg\u002Fm2\n\nExclusion Criteria:\n\n* patient's refusal\n* BMI \\>30 kg\u002Fm2\n* serious liver or kidney disease\n* ASA 4 ve more\n* anatomical abnormality at probe site\n* history of mental or neurological disease,\n* history of previous intracranial aneurysm or intracranial tumor surgery\n* history of moderate or severe pulmonary disease,\n* emergency surgery","65 Years",{"count":75,"type":20},63,"This study aims to interpret the Bispectral Index (BIS) monitoring method, which we routinely use for monitoring in scoliosis surgery, with artificial intelligence (AI) tools and to determine the accuracy and reliability of AI tools in clinical practice by comparing this interpretation with the interpretations of two clinicians experienced in BIS.",[78,79,80],"Artifical Intelligence","Bispectral Index","Spine",[82,83,84],"artificial intelligence","bispectral index","vertebra surgery","2026-06-22",{"date":87,"type":36},"2026-06-24",{"date":89,"type":20},"2026-06-10",{"date":91,"type":20},"2026-12-10",{"name":41,"class":42},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":73,"enrollmentInfo":101,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":102,"conditions":103,"keywords":107,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":114,"leadSponsor":115,"locationsCount":43},"100641782","cerebral-near-infrared-spectroscopy-in-patients-undergoing-open-cardiovascular-surgery-using-artificial-intelligence-programs-a-methodological-study-100641782","NCT07654244","Cerebral Near-infrared Spectroscopy in Patients Undergoing Open Cardiovascular Surgery Using Artificial Intelligence Programs: A Methodological Study","INTERPRETATION AND EVALUATION OF THE PROXIMITY TO CLINICAL EXPERIENCE OF CEREBRAL NEAR-INFRARED SPECTROSCOPY (NIRS) IN PATIENTS UNDERGOING OPEN CARDIOVASCULAR SURGERY USING ARTIFICIAL INTELLIGENCE PROGRAMS: A METHODOLOGICAL STUDY","NIRS for AI","Inclusion Criteria:\n\n* open cardiac surgery\n* elective open heart surgery\n* aged 18-65\n* ASA score I-III\n* BMI \\\u003C30 kg\u002Fm2\n\nExclusion Criteria:\n\n* past ischemic event\n* carotid arter stenosis\n* BMI \\>30 kg\u002Fm2\n* serious liver or kidney disease\n* ASA 4 ve more\n* anatomical abnormality at probe site\n* history of mental or neurological disease,\n* history of previous intracranial aneurysm or intracranial tumor surgery\n* history of moderate or severe pulmonary disease,\n* emergency surgery",{"count":75,"type":20},"The aim of the present study is to test the accuracy and reliability of AI tools in this regard by interpreting NIRS, which we routinely use for monitoring cerebral perfusion in cardiovascular surgery, with AI tools and comparing this interpretation with the interpretations of two clinicians.",[104,105,106],"Clinical Suitability of Artificial Intelligence Programs","Near Infrared Spectroscopy","Cardiac Surgery",[82,108,109],"near infrared spectroscopy (NIRS)","open cardiac surgery","2026-06-12",{"date":112,"type":36},"2026-06-17",{"date":89,"type":20},{"date":91,"type":20},{"name":41,"class":42},{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":124,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":126,"conditions":127,"keywords":130,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":43},"100643219","systemic-inflammatory-markers-in-vocal-cord-lesions-100643219","NCT07626125","Systemic Inflammatory Markers In Vocal Cord Lesions","Comparison Of Sysstemic Inflammatory Markers And Panimmune-Inflammatory Values In Patients With Beningn, Premalingnant And Malingnant Vocal Cord Lesions","SILVCL","Inclusion Criteria:\n\n* Patients aged 18 years and older\n* Patients with a diagnosis of vocal cord lesion via endoscopic or surgical means\n* Patients with complete blood count and albumin data in their hospital records\n\nExclusion Criteria:\n\n* Acute infection\n* Autoimmune disease\n* Other malignancy\n* Steroid use\n* Hematological disease\n* Systemic inflammatory disease\n* Missing laboratory data",{"count":125,"type":20},250,"The aim of this study is to evaluate the levels of systemic inflammatory markers such as PIV, SII, and NPAR in patients with benign and premalignant laryngeal lesions and to determine the diagnostic accuracy of these values using ROC analysis.",[128,129],"Laryngeal Lesions","Systemic Inflammatory Process",[131,132,133],"Laryngeal lesions","systemic inflammatory process","panimmun inflamation","2026-06-06",{"date":136,"type":36},"2026-06-09",{"date":138,"type":20},"2026-05-22",{"date":140,"type":20},"2026-06-19",{"name":41,"class":42},{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":147,"acronym":148,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":16,"minAge":73,"maxAge":4,"enrollmentInfo":150,"targetDuration":152,"studyType":21,"phases":4,"briefSummary":153,"conditions":154,"keywords":158,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":43},"100642685","predictive-performance-of-news-2-and-news-calcium-scores-for-in-hospital-mortality-in-older-patients-with-acute-pancreatitis-100642685","NCT07640971","Predictive Performance of NEWS-2 and NEWS-Calcium Scores for In-Hospital Mortality in Older Patients With Acute Pancreatitis","Comparison of the Predictive Performance of NEWS-2 and NEWS-Calcium Scores on In-Hospital Mortality in Patients Aged 65 Years and Older Diagnosed With Acute Pancreatitis in the Emergency Department.","NEWS","Inclusion Criteria:\n\n* Age 65 years or older.\n* Admission to the emergency department with a diagnosis of acute pancreatitis during the study period.\n* Diagnosis of acute pancreatitis established according to clinical presentation, serum pancreatic enzyme levels, and\u002For imaging findings.\n* Availability of admission vital parameters required to calculate the National Early Warning Score 2 (NEWS-2).\n* Availability of serum calcium measurement at emergency department admission.\n* Availability of in-hospital clinical outcome data.\n\nExclusion Criteria:\n\n* Age younger than 65 years.\n* Absence of a confirmed diagnosis of acute pancreatitis.\n* Missing data required to calculate NEWS-2 or NEWS-Calcium scores.\n* Missing serum calcium measurement at admission.\n* Incomplete medical records or unavailable in-hospital outcome data.\n* Transfer to another hospital before clinical outcome assessment.\n* Recurrent admissions during the study period; only the first eligible admission will be analyzed.",{"count":151,"type":20},350,"1 Month","Acute pancreatitis is an important gastrointestinal emergency that may lead to mortality, particularly in older patients. This retrospective, single-center observational prognostic validation study aims to compare the predictive performance of the National Early Warning Score 2 (NEWS-2) and NEWS-Calcium scores for in-hospital mortality in patients aged 65 years and older diagnosed with acute pancreatitis in the emergency department.\n\nElectronic medical records of eligible patients will be reviewed retrospectively. Demographic characteristics, vital signs, serum calcium levels, clinical outcomes, intensive care unit admission, organ failure, length of hospital stay, and in-hospital mortality will be recorded. NEWS-2 will be calculated using vital parameters at admission, while the NEWS-Calcium score will be obtained by adding a calcium-based score to NEWS-2.\n\nThe primary outcome will be in-hospital mortality. Secondary outcomes will include intensive care unit admission, severe acute pancreatitis, persistent organ failure, and length of hospital stay. The predictive performances of the scores will be compared using ROC curve analysis, AUC values, and the DeLong test. This study aims to identify the most appropriate early prognostic score for older patients with acute pancreatitis and to support clinical decision-making in emergency settings.",[155,156,157],"Acute Pancreatitis (AP)","News-2","Prediction of In-Hospital Mortality in Older Patients With Acute Pancreatitis",[159,31,160,161],"Acute Pancreatitis","Older Adults","Emergency Department Risk Stratification",{"date":163,"type":36},"2026-06-11",{"date":165,"type":20},"2026-07-15",{"date":167,"type":20},"2026-10-15",{"name":41,"class":42},{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":176,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":178,"conditions":179,"keywords":183,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":189,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":43},"100642262","pulmonary-artery-pressure-in-predicting-pulmonary-embolism-in-patients-presenting-to-the-emergency-department-with-dyspnea-100642262","NCT07641400","Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea","The Diagnostic Value of The Difference Between Prior and Immediate Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea","Inclusion Criteria:\n\n* Presenting to the emergency department with dyspnea between the specified dates,\n* Being 18 years of age or older,\n* Being evaluated in the emergency department with a preliminary diagnosis of pulmonary embolism,\n* Having a recorded pulmonary artery pressure measurement at the time of hospital admission,\n* Having a previous pulmonary artery pressure measurement in the patient's records,\n* Having sufficient and complete clinical, laboratory, imaging, and echocardiography data available for the study.\n\nExclusion Criteria:\n\n* Patients under 18 years of age,\n* Lack of pulmonary artery pressure data from the time of emergency admission or from the previous period,\n* Lack of necessary clinical, laboratory, or imaging data for pulmonary embolism evaluation,\n* In cases of repeated admissions for the same patient, only the first suitable admission will be considered; other admissions will be excluded from the study,\n* Patients whose data is unavailable in the record system or whose data is insufficient to be analyzed for research purposes.Inclusion Criteria for the Study",{"count":177,"type":20},80,"The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.",[180,181,182],"Emergency Department Patients","Pulmonary Hypertension","Pulmonary Embolism",[184,185,186,187,188],"emergency deparment patients","pulmonary hypertension","pulmonary embolism","dispnea","chest pain",{"date":163,"type":36},{"date":191,"type":20},"2026-06-01",{"date":193,"type":20},"2026-10-01",{"name":41,"class":42},{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":202,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":204,"conditions":205,"keywords":209,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":218,"leadSponsor":220,"locationsCount":43},"100638019","fascial-plane-blocks-in-cardiac-surgery-100638019","NCT07622823","Fascial Plane Blocks In Cardiac Surgery","The Effect Of Combined Rectus-Intercostal Fascial Plane Block Or Rectus Sheatf Block With A Pectoral-Intercostal Fascial Plane Block In Cardiac Surgery On Postoperative Opioid Consumption, Quality Of Recovery, And Chronic Pain: A Prospective, Observational Study","Inclusion Criteria:\n\n* elective cardiac surgery planned\n* over 18 years, adult\n* American Society of Anaesthesiology (ASA) score I-III\n\nExclusion Criteria:\n\n* under 18 years of age,\n* ASA IV and above,\n* contraindications for the block application\n* history of cardiac surgery,\n* reoperated due to surgery-related complications after emergency surgery or postoperative elective surgery,\n* off-pump cardiac surgery or minimally invasive cardiac surgery\n* unable to be extubated in the intensive care unit at 24 hours postoperatively\n* history of chronic pain treatment\n* chronic alcoholism and substance abuse\n* declining to give written informed consent",{"count":203,"type":20},90,"The aim of the present study is to evaluate the effects of the recto-intercostal fascial plane block (RIFPB) or the rectus sheath block (RSB) combined with the pectoral-intercostal fascial plane block (PIFPB) on postoperative analgesia in patients undergoing cardiac surgery.",[206,207,208],"Cardiovascular Surgery","Regional Anaesthesia","Postoperative Analgesia",[210,211,212,213,214],"cardiovascular surgery","pectoral-intercostal fascial plane block","recto-intercostal fascial plane block","rectus sheath block","postoperative analgesia",{"date":216,"type":36},"2026-06-03",{"date":191,"type":36},{"date":219,"type":20},"2026-12-01",{"name":41,"class":42},""]