[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ataturk University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":735},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,92,0,25,[9,50,81,107,138,164,194,222,256,283,309,331,359,393,422,446,477,505,539,572,596,626,653,684,711],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100651739","coloring-activity-applied-during-labor-in-primiparous-pregnant-women-and-its-effect-on-birth-anxiety-and-fear-of-childbirth-100651739",false,"NCT07764484","COLORING ACTIVITY APPLIED DURING LABOR IN PRIMIPAROUS PREGNANT WOMEN AND ITS EFFECT ON BIRTH ANXIETY AND FEAR OF CHILDBIRTH.","THE EFFECT OF MANDALA COLORING ACTIVITY APPLIED DURING LABOR ON BIRTH ANXIETY AND FEAR OF CHILDBIRTH IN PRIMIPAROUS PREGNANT WOMEN: A RANDOMIZED CONTROLLED TRIAL","MANDALA-RCT","Inclusion Criteria:\n\nPrimiparous pregnant women Age between 18-45 years Single pregnancy Full-term pregnancy (≥37 weeks) Planned vaginal delivery Ability to communicate and give informed voluntary consent Absence of diagnosed psychiatric disorder.\n\nExclusion Criteria:\n\nHigh-risk pregnancy status (e.g., preeclampsia) Gestational diabetes requiring insulin Indication for emergency cesarean section Hearing or cognitive impairment Use of anxiolytic or psychiatric medications Refusal to participate in the study Intranatal complications preventing participation in mandala painting intervention","FEMALE","18 Years","45 Years",{"count":22,"type":23},140,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized controlled trial aims to evaluate whether a mandala coloring activity during labor can reduce birth anxiety and fear of childbirth among primiparous pregnant women experiencing their first birth. The study will be conducted among eligible primiparous women admitted to the delivery unit at Şanlıurfa Training and Research Hospital during active labor.\n\nA total of 140 primiparous pregnant women will be randomly assigned to either an intervention group or a control group. Women in the intervention group will receive standard labor care in addition to a structured mandala coloring activity beginning when cervical dilation is between 5 and 8 cm. Participants will be provided with standardized mandala drawings and coloring pencils and will be encouraged to color during contractions as tolerated until birth. Women in the control group will receive routine labor and obstetric care without an additional art-based or distraction intervention. Routine maternal and fetal monitoring will continue in both groups throughout labor.\n\nBirth-related anxiety and fear will be assessed before the intervention during the active phase of labor and after birth. The study will use validated measures to evaluate fear of childbirth and birth-related anxiety. The study will also record relevant obstetric outcomes, including mode of delivery, analgesia use, and duration of labor.\n\nThe study seeks to answer whether adding a simple, low-cost, non-pharmacological mandala coloring activity to routine labor care can reduce birth anxiety and fear of childbirth in primiparous women. The findings may provide evidence for the use of accessible, non-pharmacological supportive interventions as part of midwifery care during labor.",[29,30],"Fear of Childbirth","Mandala Coloring",[32,33,34,35,36,37],"CHILDBIRTH FEAR","BIRTH ANXIETY","MANDALA COLORING","PRIMIPAROUS WOMEN","MATERNAL MENTAL HEALTH","NON-PHARMACOLOGICAL INTERVENTION","NOT_YET_RECRUITING","2026-08-12",{"date":41,"type":42},"2026-08-14","ACTUAL",{"date":44,"type":23},"2026-09-01",{"date":46,"type":23},"2027-01-30",{"name":48,"class":49},"Ataturk University","OTHER",{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":12,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":24,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":76,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100650725","gardening-activities-stress-and-social-interaction-in-college-students-100650725","NCT07753109","Gardening Activities, Stress, and Social Interaction Among University Students","The Effect of Gardening Activities on Peer Interaction, Stress Levels, and Nature Engagement Behaviors in University Students","Garden-Stress","Inclusion Criteria:\n\n* Being an active undergraduate student at Bingol University Vocational School of Health Services (VSHS)\n* Being between 18 and 25 years of age\n* Providing written informed consent to participate in the study\n* Having no physical disability or chronic illness preventing outdoor physical activity\n* Having no known pollen or soil allergies\n\nExclusion Criteria:\n\n* Absence from more than 25% of the sessions (missing more than 2 sessions) during the intervention\n* Initiating a new professional psychiatric or psychological treatment process during the study period","ALL","18 Months","25 Months",{"count":62,"type":23},100,[26],"This study is a quasi-experimental research project with a pretest-posttest control group design, structured to determine the effect of organized gardening activities on peer interaction, stress levels, and nature engagement behaviors among university students.The population of the research consists of students from the Vocational School of Health Services (VSHS) at Bingol University. The sample size, determined via G\\*Power analysis (including a 20% anticipated drop-out rate), comprises a total of 100 volunteer students, divided into an intervention group (n = 50) and a control group (n = 50).The intervention group will participate in a structured program held twice weekly for 1 month (totaling 8 sessions, 60-90 minutes each) in the VSHS garden, encompassing soil preparation, paired seedling planting, group-oriented maintenance, and landscaping activities. The control group will maintain their routine campus life.Data will be collected using a Personal Information Form, the Perceived Self-Efficacy Scale (Coping with Stress), the University Life Scale (Peer Relations Subscale), and the Connectedness to Nature Scale. The data will be evaluated through homogeneity tests and parametric\u002Fnon-parametric comparative analyses (t-tests, Wilcoxon, Mann-Whitney U).Contingency plans (Plan B)-such as indoor potted plant\u002Fterrarium workshops and buffer sample recruitment-are established to address adverse weather conditions, sample attrition, and seasonal risks.",[66,67,68],"Psychosocial Wellbeing","Perceived Stress","Peer Interaction in University Students",[70,71,67,72,73,74,75],"Gardening Activities","Horticultural Therapy","Peer Interaction","Nature Engagement","University Students","Quasi-Experimental Study",{"date":41,"type":42},{"date":44,"type":23},{"date":79,"type":23},"2027-01-01",{"name":48,"class":49},{"id":82,"slug":83,"hasResults":12,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":12,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":89,"targetDuration":4,"studyType":24,"phases":90,"briefSummary":91,"conditions":92,"keywords":97,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":105,"leadSponsor":106,"locationsCount":4},"100651560","impact-of-generative-ai-on-university-students-learning-processes-and-critical-thinking-100651560","NCT07762261","Impact of Generative AI on University Students' Learning Processes and Critical Thinking","An Experimental Investigation of the Effects of Generative Artificial Intelligence-Supported Learning on University Students' Academic Success, Learning Efficiency, and Critical Thinking Skills","AI-Critical","Inclusion Criteria:\n\n* Being an active undergraduate student enrolled in the university program\u002Fcourse during the study period\n* Willingness to voluntarily participate in the study and providing written informed consent\n* Having regular access to a digital device (e.g., smartphone, laptop, tablet) and an internet connection\n* Basic digital literacy to use educational software and AI tools\n* Agreeing to complete all course activities, pre-tests, and post-test\n\nExclusion Criteria:\n\n* Prior formal or advanced training in generative AI tools (e.g., prompt engineering certification)\n* Transfer students or students repeating the course who have prior experience with the course material\n* Having cognitive, visual, or physical impairments that prevent participation in online learning or completing evaluation surveys\n* Unwillingness to participate in the study or withdrawing consent at any stage\n* Missing more than 20% of the course sessions or failing to complete the outcome assessment tools (pre-test\u002Fpost-test)",{"count":62,"type":23},[26],"This study is a randomized, controlled trial with a pre-test\u002Fpost-test design, conducted to determine the effects of Generative AI (GenAI)-supported learning on academic achievement, learning efficiency, and critical thinking within a university setting. The study population consists of students from the Dialysis Program at Bingöl University's Vocational School of Health Services; the sample comprises 100 volunteer students who met the inclusion criteria and were randomly assigned to either an experimental group (n=50) or a control group (n=50). The experimental group will participate in a \"Generative AI-Supported Learning Program\" over the course of one month-meeting two days a week for a total of eight 60-minute sessions-covering topics ranging from effective prompting techniques to case analysis and academic ethics; meanwhile, the control group will continue with their routine educational activities. Data will be collected using a Demographic Information Form, the Academic Achievement Inventory, the Critical Thinking Disposition Scale, and the Artificial Intelligence Dependency Scale, and will be analyzed using biostatistical methods (t-tests, ANCOVA, and effect size calculations).",[93,94,95,96],"Education","Academic Performance","Learning Efficiency","Generative Artificial Intelligence",[96,98,99,95,100],"Artificial Intelligence in Education","Academic Success","Critical Thinking","2026-08-08",{"date":103,"type":42},"2026-08-13",{"date":44,"type":23},{"date":79,"type":23},{"name":48,"class":49},{"id":108,"slug":109,"hasResults":12,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":24,"phases":117,"briefSummary":118,"conditions":119,"keywords":122,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},"100651011","minimally-invasive-non-surgical-periodontal-treatment-100651011","NCT07755644","Minimally Invasive Non-Surgical Periodontal Treatment","The Clinical Effects of Minimally Invasive NonSurgical Therapy (MINST) as an Alternative of Conventional NonSurgical Periodontal Therapy for Stage III Grade C Periodontitis in Molar Teeth- A 6-month Pilot Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 to 35 years.\n* Diagnosed with Stage III or Stage IV periodontitis.\n* Systemically healthy.\n* Presence of at least two bilateral molar teeth with probing pocket depth (PPD) ≥5 mm and bleeding on probing (BOP).\n* At least 20 remaining teeth.\n* Radiographic evidence of periodontal bone loss.\n* Non-smokers and non-users of tobacco or alcohol.\n* Not pregnant or breastfeeding.\n* Not receiving medications known to affect periodontal healing.\n* Willing and able to provide written informed consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Individuals who do not meet the inclusion criteria.\n* Pregnancy or breastfeeding.\n* Presence of systemic diseases or medical conditions affecting periodontal status or healing.\n* Current use of medications that may influence periodontal healing.\n* Current smokers or users of tobacco or alcohol.\n* Individuals unwilling or unable to provide informed consent.","35 Years",{"count":116,"type":23},23,[26],"This single-center, split-mouth, randomized controlled clinical trial aims to evaluate the clinical effectiveness of Minimally Invasive Non-Surgical Therapy (MINST) as an adjunct to conventional non-surgical periodontal therapy in patients with Stage III\u002FIV periodontitis. Twenty-three systemically healthy adults presenting with bilateral molar teeth exhibiting periodontal pockets ≥5 mm with bleeding on probing will be enrolled. In each participant, molar teeth will be randomly allocated to receive either conventional subgingival scaling and root planing (SRP) using ultrasonic instruments alone (control) or conventional SRP followed by MINST using Mini-Five Gracey curettes under magnification loupes (test). Clinical periodontal parameters, including Plaque Index (PI), Gingival Index (GI), Bleeding on Probing (BOP), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL), will be evaluated at baseline, 3 months, and 6 months after treatment. The study will investigate whether MINST provides superior clinical outcomes compared with conventional non-surgical periodontal therapy.",[120,121],"Periodontitis","Periodontitis (Stage 3)",[120,123,124,125,126,127,128],"Stage III Periodontitis","Stage IV Periodontitis","Minimally Invasive Non-Surgical Therapy","MINST","Scaling and Root Planing","Root Debridement","2026-08-05",{"date":131,"type":42},"2026-08-10",{"date":133,"type":23},"2026-08-01",{"date":135,"type":23},"2027-01",{"name":48,"class":49},1,{"id":139,"slug":140,"hasResults":12,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":4,"eligibilityCriteria":144,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":24,"phases":147,"briefSummary":148,"conditions":149,"keywords":151,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":163,"locationsCount":137},"100649027","menopause-and-compassionate-living-education-100649027","NCT07728461","Menopause and Compassionate Living Education","The Effect of Compassionate Living Education on Symptom Management and Quality of Life in Menopausal Women: A Randomized Controlled Study","Inclusion Criteria:\n\n* Women who are in the menopausal period.\n* Aged 45 years or older.\n* Registered at the participating primary healthcare center.\n* Able to read and understand Turkish.\n* At least a primary school graduate.\n* Willing to participate and provide written informed consent.\n* Able to attend the online Compassionate Living Education sessions.\n* Able to complete the study questionnaires.\n\nExclusion Criteria:\n\n* Failure to complete the study questionnaires.\n* Failure to attend the Compassionate Living Education sessions.\n* Withdrawal of informed consent at any stage of the study.\n* Inability to complete the post-intervention assessment.",{"count":146,"type":23},68,[26],"Menopause is a natural stage in a woman's life characterized by the permanent cessation of ovarian function and is frequently accompanied by vasomotor, psychological, urogenital, and sleep-related symptoms that can substantially impair quality of life. Although pharmacological treatments are available, many women seek non-pharmacological interventions to manage menopausal symptoms and improve their overall well-being. Mindfulness- and compassion-based interventions have shown promising effects on psychological health, stress reduction, and quality of life in different populations; however, evidence regarding the effectiveness of Mindfulness-Based Compassionate Living (MBCL) for women experiencing menopause remains limited.\n\nThis randomized controlled trial aims to evaluate the effectiveness of a Compassionate Living Education Program based on the principles of Mindfulness-Based Compassionate Living in improving symptom management and quality of life among menopausal women. The study will be conducted with menopausal women recruited from primary healthcare settings in Kars, Türkiye. Participants who meet the eligibility criteria will be randomly assigned to either an intervention group or a control group.\n\nParticipants in the intervention group will receive an eight-session online Compassionate Living Education Program delivered by a certified instructor. The program includes mindfulness practices, self-compassion exercises, breathing and relaxation techniques, compassionate imagery, loving-kindness meditation, and home practice assignments designed to strengthen emotional regulation, self-kindness, and adaptive coping skills. The control group will receive routine care only.\n\nPrimary outcomes will include menopausal symptom severity and menopause-specific quality of life. Secondary outcomes will include self-compassion, mindfulness, anxiety, depression, and stress. Data will be collected using validated self-report questionnaires before and after the intervention and analyzed using appropriate statistical methods.\n\nThe findings of this study are expected to provide evidence regarding the effectiveness of Compassionate Living Education as an accessible, low-cost, non-pharmacological intervention for improving symptom management and enhancing the quality of life of menopausal women. The results may contribute to the development of evidence-based nursing and women's health interventions in primary healthcare settings.",[150],"Mindfulness Compassionate Living Training",[152,153,154,155,156],"mindfulness","self-compassion","Quality of life","Menopause","Women","2026-07-22",{"date":159,"type":42},"2026-07-27",{"date":161,"type":23},"2026-09-30",{"date":46,"type":23},{"name":48,"class":49},{"id":165,"slug":166,"hasResults":12,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":171,"sex":58,"minAge":19,"maxAge":4,"enrollmentInfo":172,"targetDuration":4,"studyType":24,"phases":174,"briefSummary":175,"conditions":176,"keywords":182,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":4},"100645920","the-effect-of-intravenous-injection-training-based-on-the-arcs-v-model-on-levels-of-learning-motivation-and-self-efficacy-100645920","NCT07691983","The Effect of Intravenous Injection Training Based on the ARCS-V Model on Levels of Learning Motivation and Self-Efficacy","The Effect of Intravenous Injection Training Based on the ARCS-V Model on Nursing Students' Learning Motivation and Self-Efficacy Levels: A Mixed-Methods Study","Inclusion Criteria:\n\n* To be a student enrolled on the Turkish-language programme at the Faculty of Nursing,\n* Be aged 18 or over,\n* Have Turkish as your first language,\n* Be a first-year student,\n* Not be a student on an exchange programme such as Erasmus,\n* Be taking the 'Fundamentals of Nursing' course for the first time,\n* Not have previously received training in intravenous procedures\n* Not to have been absent during the period when research data will be collected, Not to hold a secondary school, foundation year or undergraduate degree in any health-related field\n\nExclusion Criteria:\n\n* The desire not to take part in any stage of the research or to withdraw from the research",true,{"count":173,"type":23},76,[26],"Intravenous (IV) administration, one of the most fundamental and common practices carried out by nurses, is defined as the administration of medication directly into the circulatory system via a vein. Intravenous administration is one of the key clinical skills that must be performed using the correct technique. Supporting students' motivation to learn plays a significant role in the effective acquisition of this skill. The ARCS-V motivation model, which aims to enhance motivation during the teaching process, comprises the dimensions of attention, relevance, confidence, satisfaction and action. This study aims to investigate the effect of intravenous administration training based on the ARCS-V model on nursing students' levels of motivation and academic self-efficacy. The study will be conducted using a mixed-methods design incorporating both a randomised controlled trial and qualitative research methods. In the study, the experimental group will receive IV administration training structured according to the ARCS-V model, whilst the control group will be taught using the traditional teaching method. For the collection of quantitative data in this study, the \"Demographic Information Form\", the \"Motivation Scale for Teaching Materials (ÖMMÖ)\", the \"Academic Self-Efficacy Scale (AÖÖ)\" and the \"Volition to Learn Scale (VFLS)\" will be used. For the collection of qualitative data in the study, a \"Semi-Structured Interview Form\" will be used to determine the experiences of students in the experimental group regarding the learning process, and an audio recorder will be used to record the data. Whilst the quantitative data obtained will be analysed using statistical methods, the qualitative data will be evaluated through content analysis. It is anticipated that the findings of this research will demonstrate that teaching based on the ARCS-V model contributes to clinical skills training by supporting students' active participation in the learning process, as well as their motivation and will to learn.",[177,178,179,180,181],"Nurse Education","Intravenous Catheters","INTRAVENOUS CATHETER APPLICATION","Intravenous Therapy","Intravenous Therapy Complications",[183,184,185],"ARCS-V","Nursing Education","Motivation","2026-07-10",{"date":188,"type":42},"2026-07-13",{"date":190,"type":23},"2026-07-15",{"date":192,"type":23},"2027-12-26",{"name":48,"class":49},{"id":195,"slug":196,"hasResults":12,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":171,"sex":58,"minAge":19,"maxAge":4,"enrollmentInfo":201,"targetDuration":4,"studyType":203,"phases":4,"briefSummary":204,"conditions":205,"keywords":207,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":137},"100645948","relationship-between-metrnl-expression-il-1-and-tnf--in-patients-with-peri-implantitis-100645948","NCT07697729","Relationship Between Metrnl Expression, IL-1β, and TNF-α in Patients With Peri-Implantitis","Association of Metrnl Expression With IL-1β and TNF-α in Patients With Peri-Implantitis: Potential as a Novel Biomarker","Inclusion Criteria:\n\n* Individuals aged 18 years or older\n* Individuals without systemic disease\n* Individuals with at least one healthy implant or one implant affected by peri-implantitis\n* At least 1 year having elapsed since placement of the prosthetic restoration on the relevant implant\n\nExclusion Criteria:\n\n* Pregnant or lactating individuals.\n* Current smokers.\n* Use of antibiotics or corticosteroids within the previous 6 months.\n* Presence of an implant-supported removable prosthesis.\n* Periodontal or peri-implant treatment within the previous 6 months.",{"count":202,"type":23},60,"OBSERVATIONAL","Peri-implantitis is an inflammatory disease affecting the tissues around dental implants and may lead to progressive bone loss and implant failure. Current diagnosis is mainly based on clinical and radiographic findings, which may not fully reflect the underlying inflammatory activity. Therefore, there is a need for biological markers that may provide additional information about disease-related changes.\n\nThis observational study aims to compare the levels of Meteorin-like protein (Metrnl) and selected inflammatory cytokines in peri-implant crevicular fluid obtained from individuals with peri-implantitis and individuals with healthy implants. The study will evaluate Metrnl, interleukin-1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and interleukin-10 (IL-10). It will also examine the relationships between Metrnl and these inflammatory markers.\n\nThe study hypothesis is that Metrnl levels differ between healthy peri-implant tissues and peri-implantitis and are associated with pro-inflammatory and anti-inflammatory cytokine levels. The findings may help clarify the possible role of Metrnl in peri-implant inflammation and its potential as a biomarker for distinguishing peri-implant health from peri-implantitis.",[206],"Peri-implantitis",[208,209,210,211,212,213,214],"Meteorin-Like Protein","Metrnl","Peri-Implant Crevicular Fluid","Interleukin-1 Beta","Tumor Necrosis Factor-Alpha","Interleukin-10","Dental Implants","2026-07-09",{"date":188,"type":42},{"date":218,"type":23},"2026-07-07",{"date":220,"type":23},"2026-08-02",{"name":48,"class":49},{"id":223,"slug":224,"hasResults":12,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":12,"sex":229,"minAge":230,"maxAge":231,"enrollmentInfo":232,"targetDuration":4,"studyType":24,"phases":234,"briefSummary":235,"conditions":236,"keywords":242,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":249,"lastUpdatePostDateStruct":250,"startDateStruct":251,"completionDateStruct":253,"leadSponsor":255,"locationsCount":137},"100633338","the-effect-of-progressive-relaxation-exercises-with-therapeutic-clown-100633338","NCT07525388","The Effect of Progressive Relaxation Exercises With Therapeutic Clown","The Effect of Progressive Relaxation Exercises With Therapeutic Clown in Preoperative Period on Fear Anxiety and Physiological Parameters in Children","Inclusion Criteria:\n\n* Aged between 6 and 10 years,\n* Willing to participate in the study,\n* Admitted to the clinic for elective circumcision surgery,\n* Accessible prior to surgery,\n* With no cognitive impairments,\n* With no vision or hearing problems were included in the study.\n\nExclusion Criteria:\n\n* Children who wished to withdraw from the study during the study period were excluded.","MALE","6 Years","10 Years",{"count":233,"type":23},162,[26],"This study was conducted to investigate the effects of progressive relaxation exercises, performed with the assistance of a therapeutic clown during the pre-operative period, on fear, anxiety and physiological parameters in children. This randomised controlled trial included children aged 6-10 years undergoing circumcision surgery. The children were randomised into three groups: a progressive relaxation exercise group led by a therapeutic clown, a progressive relaxation group led by a nurse, and a control group. Fear, anxiety and physiological parameters (heart rate, respiratory rate, blood pressure, oxygen saturation) were assessed before and after the procedure.",[237,238,239,240,241],"Therapeutic Clown","Relaxation Exercise","Anxiety","Fear","Surgery",[243,244,245,246,247],"therapeutic clown","relaxation exercise","fear","anxiety","surgery","RECRUITING","2026-07-03",{"date":218,"type":42},{"date":252,"type":42},"2025-03-25",{"date":254,"type":23},"2026-06-30",{"name":48,"class":49},{"id":257,"slug":258,"hasResults":12,"nctId":259,"briefTitle":260,"officialTitle":261,"acronym":4,"eligibilityCriteria":262,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":263,"enrollmentInfo":264,"targetDuration":4,"studyType":24,"phases":266,"briefSummary":267,"conditions":268,"keywords":270,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":276,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":4},"100643626","effects-of-oxygen-cage-support-during-cataract-surgery-100643626","NCT07632326","Effects of Oxygen Cage Support During Cataract Surgery","The Effect of Oxygen Support Cage Material Use During Cataract Surgery on Operation Time, Anxiety, Physiological Parameters, and Patient Experiences: A Mixed Methods Study","Inclusion Criteria\n\n* Willing to participate in the study voluntarily and provides informed consent\n* Aged 18 years or older\n* Having no hearing or cognitive impairments\n* Undergoing cataract surgery for the first time Exclusion Criteria\n* Conversion from local anesthesia to general anesthesia during the surgery\n* Patient's non-participation or refusal to complete the anxiety assessment during the surgery","90 Years",{"count":265,"type":23},70,[26],"Cataract is an ocular disorder resulting from lens opacity; it stands as the most common cause of preventable blindness worldwide and significantly impairs the quality of life in elderly individuals. Surgical treatment utilizing small-incision phacoemulsification is the most effective solution for cataracts. Cataract surgery is generally performed under local anesthesia, which requires patients to remain awake throughout the operation, thereby potentially increasing their anxiety experiences. Elevated anxiety not only reduces patient comfort but can also lead to alterations in physiological parameters and a prolongation of the operation time. Furthermore, it is observed that the surgical drapes used to maintain the sterility of the surgical field during the operation cause discomfort to the patient. The weight and positioning of these drapes can cover the patient's mouth and nose area during the ongoing surgery, creating a sensation of difficulty in breathing (dyspnea). In addition to these circumstances, standard oxygen support is provided to the patient during cataract surgery performed under local anesthesia. This support is administered nasally via an open-ended oxygen tubing from beneath the surgical drape, aiming to ease the patient's respiration. However, when the oxygen flow rate is increased based on the patient's needs, high-velocity and high-concentration oxygen administration is observed to cause mucosal dryness, which shortly triggers reflex-induced irritative coughing attacks. For these reasons, it is crucial to keep anxiety under control, provide oxygen to prevent hypoxia, and monitor physiological parameters during cataract surgery.",[269],"Cataract",[271,272,239,273,274],"Cataract Surgery","Oxygen Support","Patient Experience","Surgical Nursing","2026-06-23",{"date":277,"type":42},"2026-06-26",{"date":279,"type":23},"2026-07-01",{"date":281,"type":23},"2027-05-01",{"name":48,"class":49},{"id":284,"slug":285,"hasResults":12,"nctId":286,"briefTitle":287,"officialTitle":288,"acronym":4,"eligibilityCriteria":289,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":4,"enrollmentInfo":290,"targetDuration":4,"studyType":24,"phases":292,"briefSummary":293,"conditions":294,"keywords":296,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":302,"lastUpdatePostDateStruct":303,"startDateStruct":305,"completionDateStruct":307,"leadSponsor":308,"locationsCount":4},"100641339","the-effect-of-act-based-nursing-interventions-on-social-cognition-emotion-regulation-and-psychological-flexibility-in-patients-with-schizophrenia-100641339","NCT07661225","The Effect of ACT-Based Nursing Interventions on Social Cognition, Emotion Regulation and Psychological Flexibility in Patients With Schizophrenia","The Effect of Acceptance and Commitment Therapy (ACT)-Based Nursing Interventions on Social Cognition, Emotion Regulation and Psychological Flexibility in Individuals With Schizophrenia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with schizophrenia (ICD-10\u002FDSM-5) and followed at Erzincan Community Mental Health Center (TRSM)\n* Registered at Erzincan TRSM\n* Duration of schizophrenia diagnosis of at least 6 months\n* No cognitive or sensory (hearing\u002Fvisual) deficit that would prevent participation\n* Literate\n* Provides written informed consent to participate\n\nExclusion Criteria:\n\n* Comorbid psychiatric diagnosis other than schizophrenia\n* Active acute psychotic episode at enrollment\n\nDiscontinuation \u002F Withdrawal Criteria\n\n* Voluntary withdrawal from the study\n* Acute psychotic relapse during the study period\n* Additional psychiatric diagnosis during the study period\n* Radical change in medication type or dosage during the study period\n* Incomplete responses on data collection forms\n* Completion of less than 80% of assigned homework",{"count":291,"type":23},64,[26],"This randomized controlled trial aims to evaluate the effect of Acceptance and Commitment Therapy (ACT)-based nursing interventions on social cognition, emotion regulation, and psychological flexibility in individuals diagnosed with schizophrenia. The study will be conducted at Erzincan Community Mental Health Center (TRSM) between October 2026 and January 2027. A total of 64 participants (32 experimental, 32 control) will be recruited from schizophrenia patients registered at the center. The experimental group will receive 8 structured group sessions based on ACT principles integrated into nursing practice (45-60 minutes per session, once weekly), while the control group will receive routine care only. Pre-test and post-test measurements will be obtained using the Observable Social Cognition Rating Scale (OSCARS), the Difficulties in Emotion Regulation Scale-Brief Form (DERS-16), and the Acceptance and Action Questionnaire-II (AAQ-II).",[295],"SCHIZOPHRENIA 1 (Disorder)",[297,298,299,300,301],"Acceptance and Commitment Therapy","ACT-based nursing intervention","Social cognition","Emotion regulation","Psychological flexibility","2026-06-18",{"date":304,"type":42},"2026-06-22",{"date":306,"type":23},"2026-10",{"date":135,"type":23},{"name":48,"class":49},{"id":310,"slug":311,"hasResults":12,"nctId":312,"briefTitle":313,"officialTitle":314,"acronym":4,"eligibilityCriteria":315,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":316,"targetDuration":4,"studyType":24,"phases":317,"briefSummary":318,"conditions":319,"keywords":321,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":324,"lastUpdatePostDateStruct":325,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":4},"100642135","emotional-freedom-techniques-in-nursing-students-with-primary-dysmenorrhea-100642135","NCT07658859","Emotional Freedom Techniques in Nursing Students With Primary Dysmenorrhea","Effect of Emotional Freedom Techniques on Pain Intensity, Pain Catastrophizing, and Functional-Emotional Impact in Nursing Students With Primary Dysmenorrhea","Inclusion Criteria:\n\n* Being enrolled in a nursing program,\n* Being 18 years of age or older\n* Having had a regular menstrual cycle within the last six months\n* Experiencing primary dysmenorrhea during the last three menstrual cycles\n* Reporting moderate to severe pain according to the Visual Analog Scale (VAS: 4-10)\n* Voluntary participation in the study\n* Providing written informed consent\n\nExclusion Criteria:\n\n* Having a diagnosed gynecological disease that may cause secondary dysmenorrhea (endometriosis, adenomyosis, uterine fibroids, pelvic inflammatory disease, etc.)\n* Having chronic pain syndrome\n* Receiving regular treatment or taking psychiatric medication due to a psychiatric diagnosis\n* Applying another pharmacological or non-pharmacological intervention that may affect pain perception during the research process,\n* Taking the course Obstetrics, Gynecology and Women's Health Nursing • Receiving\u002Fhaving received emotional freedom technique training,\n* Having previously received training in this technique or regularly using it\n* Having a cognitive or sensory problem that prevents communication or completing data collection forms\n* Not completing the application protocol\n* Incomplete completion of data collection forms\n* Wishing to withdraw from the research",{"count":5,"type":23},[26],"This study will examine whether Emotional Freedom Techniques (EFT) can reduce pain intensity, pain catastrophizing, and functional-emotional impact in nursing students with primary dysmenorrhea. Eligible participants will be randomly assigned to an intervention group or a control group. The intervention group will receive EFT-based support, and the control group will continue their usual coping practices. Study outcomes will be measured before the intervention, after the intervention, and at follow-up. This study may provide evidence for a safe, non-pharmacological approach to support students with primary dysmenorrhea.",[320],"PRIMARY DYSMENORRHEA",[320,322,323],"EMOTIONAL FREEDOM TECHNIQUES","NURSING STUDENTS","2026-06-17",{"date":304,"type":42},{"date":327,"type":23},"2026-06-19",{"date":329,"type":23},"2026-12-19",{"name":48,"class":49},{"id":332,"slug":333,"hasResults":12,"nctId":334,"briefTitle":335,"officialTitle":336,"acronym":4,"eligibilityCriteria":337,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":338,"targetDuration":4,"studyType":24,"phases":340,"briefSummary":341,"conditions":342,"keywords":345,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":356,"leadSponsor":358,"locationsCount":4},"100642414","artificial-intelligence-powered-digital-education-based-on-the-neuman-systems-model-for-breast-cancer-patients-receiving-radiotherap-100642414","NCT07649902","Artificial Intelligence Powered Digital Education Based on the Neuman Systems Model for Breast Cancer Patients Receiving Radiotherap","The Effect of Artificial Intelligence-Powered Digital Education Based on the Neuman Systems Model on Radiodermatitis Severity and Quality of Life in Breast Cancer Patients","Inclusion Criteria:\n\n* Women aged 18 years or older diagnosed with primary breast cancer who have completed surgical treatment and are scheduled to receive adjuvant radiotherapy.\n* Patients who will receive radiotherapy for the first time.\n* Patients whose general health condition is suitable for participation in the study and follow-up assessments.\n* Patients who are able to read, understand, and communicate in Turkish.\n* Patients who have access to the internet and are able to use a smartphone, tablet, or computer to access the digital education program.\n* Patients who voluntarily agree to participate in the study and provide written informed consent.\n\nExclusion Criteria:\n\n* Previous radiotherapy to the same treatment area.\n* Presence of an active infection, open wound, or severe dermatological disease within the radiation treatment field.\n* History of a chronic skin condition that may affect radiation-induced skin reactions.\n* Cognitive or psychiatric conditions that may prevent participants from following the educational program or complying with the study procedures and data collection process.",{"count":339,"type":23},38,[26],"The purpose of this clinical trial is to evaluate the effect of an artificial intelligence-supported digital education program developed based on the Neuman Systems Model on radiodermatitis severity and quality of life in women with breast cancer receiving radiotherapy.\n\nThe intervention was developed based on the Neuman Systems Model, which served as the theoretical framework of the study. Educational content was structured according to the principles of the model and was designed to strengthen patients' flexible lines of defense, support resistance resources, facilitate adaptation to radiotherapy-related stressors, and promote system stability through primary, secondary, and tertiary prevention strategies.\n\nThe study aims to answer the following questions:\n\n* Is a Neuman Systems Model-based AI-supported digital education program effective in reducing the severity of radiotherapy-induced radiodermatitis?\n* Is a Neuman Systems Model-based AI-supported digital education program effective in improving quality of life among women receiving radiotherapy for breast cancer? Participants assigned to the intervention group will be provided with access to the AI-supported digital education program developed in accordance with the Neuman Systems Model, whereas participants assigned to the control group will receive standard care. Differences between the groups with respect to radiodermatitis severity and quality of life outcomes will be evaluated.\n\nParticipants will complete a Patient Information Form to collect sociodemographic and clinical characteristics prior to the initiation of radiotherapy. Radiodermatitis severity will be assessed using the Radiation Therapy Oncology Group (RTOG) Acute Radiation Dermatitis Scale, and quality of life will be evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the breast cancer-specific module (EORTC QLQ-BR23). Following these assessments, participants will be randomly allocated to either the intervention group or the control group. Radiodermatitis severity will be evaluated weekly throughout the radiotherapy period using the RTOG scale and reassessed two weeks after completion of radiotherapy. Quality of life will be evaluated before radiotherapy and reassessed two weeks after completion of radiotherapy using the EORTC QLQ-C30 and EORTC QLQ-BR23 questionnaires. Participants assigned to the intervention group will be provided with access to an AI-supported digital education platform incorporating educational modules, personalized educational recommendations, reminder notifications, and motivational messages. In addition, system usability will be evaluated at the end of the intervention period using the System Usability Scale (SUS).",[343,344],"Breast Cancer","Radiodermatitis",[343,346,344,347,348,349,350,351],"Radiotherapy","Quality of Life","Artificial Intelligence","Digital Education","Neuman Systems Model","Nursing Intervention","2026-06-11",{"date":354,"type":42},"2026-06-16",{"date":133,"type":23},{"date":357,"type":23},"2027-07-01",{"name":48,"class":49},{"id":360,"slug":361,"hasResults":12,"nctId":362,"briefTitle":363,"officialTitle":364,"acronym":4,"eligibilityCriteria":365,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":366,"enrollmentInfo":367,"targetDuration":4,"studyType":203,"phases":4,"briefSummary":368,"conditions":369,"keywords":373,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":385,"lastUpdatePostDateStruct":386,"startDateStruct":388,"completionDateStruct":390,"leadSponsor":392,"locationsCount":137},"100640532","labor-epidural-analgesia-and-mother-infant-bonding-after-vaginal-delivery-100640532","NCT07582289","Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery","Association Between Postpartum Recovery Quality Measured by ObsQoR-10 and Mother-Infant Bonding After Vaginal Delivery: The Role of Labor Epidural Analgesia","Inclusion Criteria:\n\n* Female participants aged 18 to 40 years\n* Term singleton pregnancy (≥37 weeks)\n* Planned vaginal delivery\n* ASA physical status II\n* Ability to understand Turkish\n* Written informed consent\n\nExclusion Criteria:\n\n* Contraindications to epidural analgesia including coagulopathy, anticoagulant use, infection, or increased intracranial pressure\n* Cesarean delivery\n* High-risk pregnancy\n* Neonatal intensive care unit requirement\n* Major depressive disorder\n* Anxiety disorder\n* Current psychotropic medication use","40 Years",{"count":22,"type":23},"This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery. Postpartum recovery quality will be assessed using the Obstetric Quality of Recovery-10 (ObsQoR-10) questionnaire, and mother-infant bonding will be evaluated using the Postpartum Bonding Questionnaire (PBQ).\n\nParticipants will be grouped according to routine clinical labor analgesia preference: women receiving labor epidural analgesia and women not receiving epidural analgesia. Additional assessments will include postpartum pain intensity, anxiety, depressive symptoms, and birth satisfaction.\n\nBaseline psychological assessments will be performed before delivery. The primary postpartum evaluation will be conducted between 6 and 24 hours after delivery. Exploratory follow-up assessments will be performed by telephone during postpartum week 2.\n\nThe study aims to better understand the relationship between labor analgesia, postpartum recovery, and early mother-infant bonding outcomes after vaginal delivery.",[370,371,372],"Postpartum Recovery","Mother-infant Bonding","Labor Pain",[374,375,376,377,378,379,380,370,381,382,383,384],"Labor Epidural Analgesia","Postpartum Bonding Questionnaire","PBQ","EPDS","STAIS-5","ObsQoR-10","Vaginal Birth","Maternal Bonding","Obstetric Anesthesia","Postpartum Anxiety","Postpartum Depression","2026-05-30",{"date":387,"type":42},"2026-06-03",{"date":389,"type":23},"2026-05-15",{"date":391,"type":23},"2029-06-17",{"name":48,"class":49},{"id":394,"slug":395,"hasResults":12,"nctId":396,"briefTitle":397,"officialTitle":398,"acronym":399,"eligibilityCriteria":400,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":401,"enrollmentInfo":402,"targetDuration":4,"studyType":24,"phases":403,"briefSummary":404,"conditions":405,"keywords":407,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":137},"100640729","mindfulness-training-in-type-2-diabetes-100640729","NCT07617766","Mindfulness Training in Type 2 Diabetes","The Effect of Mindfulness-Based Self-Management Education on Diabetes-Related Difficulties and Empowerment in Individuals With Type 2 Diabetes","MindfulT2DCA","Inclusion Criteria:\n\n* Aged between 18 and 65 years.\n\nDiagnosed with Type 2 diabetes mellitus.\n\nLiterate (able to read and write).\n\nHas access to and is able to actively use a smartphone or internet.\n\nNo diagnosed mental or cognitive impairment.\n\nWilling to participate voluntarily and provide informed consent.\n\nExclusion Criteria:\n\n* Previously received structured education related to their diabetes.\n\nPregnant.\n\nCurrently participating in another research study.\n\nHospitalized due to diabetes-related complications.\n\nUnable to complete the education program.","65 Years",{"count":265,"type":23},[26],"This study aims to evaluate the effects of mindfulness-based self-management education on diabetes-related difficulties and empowerment in individuals with type 2 diabetes. Participants will receive a structured education program designed to improve self-care behaviors, emotional well-being, and confidence in managing their condition.\n\nThe program includes mindfulness practices, diabetes self-management education, and supportive group sessions. Outcomes such as diabetes distress, self-management behaviors, and patient empowerment will be measured before and after the intervention.\n\nThe findings of this study are expected to contribute to improving patient-centered care and supporting individuals with type 2 diabetes in managing their health more effectively.",[406],"Type 2 Diabetes Mellitus (T2DM)",[408,409,410,411,412,413],"Mindfulness","Type 2 diabetes","Self-management education","Patient empowerment","Behavioral intervention","Diabetes difficulties","2026-05-24",{"date":416,"type":42},"2026-06-01",{"date":418,"type":23},"2026-05",{"date":420,"type":23},"2027-05",{"name":48,"class":49},{"id":423,"slug":424,"hasResults":12,"nctId":425,"briefTitle":426,"officialTitle":427,"acronym":428,"eligibilityCriteria":429,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":4,"enrollmentInfo":430,"targetDuration":4,"studyType":24,"phases":432,"briefSummary":433,"conditions":434,"keywords":436,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":439,"startDateStruct":441,"completionDateStruct":443,"leadSponsor":445,"locationsCount":137},"100621796","effects-of-biceps-transposition-without-tenotomy-for-augmentation-of-massive-rotator-cuff-repairs-100621796","NCT07375277","Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs","Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs On Function, Quality Of Life, And Sleep: A Prospective Study","ROTATORCUFF","Inclusion Criteria:\n\n* Age 18 years or older\n* Diagnosis of a massive rotator cuff tear on preoperative MRI, defined as a full-thickness tear involving at least two tendons and\u002For a tear with a greatest dimension greater than 5 cm\n* Planned arthroscopic partial rotator cuff repair with augmentation using tenotomy-sparing long head of the biceps tendon (LHBT) transposition\n* Persistence of symptoms despite at least 3 months of standard nonoperative treatment\n* Intact LHBT confirmed intraoperatively\n* Willingness and ability to attend scheduled follow-up visits (baseline, 3 months, and 12 months)\n* Provision of written informed consent\n\nExclusion Criteria:\n\nExclusion Criteria:\n\n* Tear patterns not requiring augmentation (e.g., preserved rotator cable patterns)\n* Neurologic conditions, inflammatory arthritis, active infection, or systemic conditions that may affect shoulder function or prevent protocol rehabilitation\n* Inability to provide informed consent\n* Expected nonadherence to follow-up or rehabilitation protocol",{"count":431,"type":23},35,[26],"This prospective, single-arm interventional study will evaluate the effects of long head of the biceps tendon (LHBT) transposition without tenotomy as an augmentation technique for arthroscopic partial repair in adults with massive rotator cuff tears. Consecutive eligible patients undergoing arthroscopic partial rotator cuff repair plus tenotomy-sparing LHBT transposition augmentation at Balikesir City Hospital (Balikesir, Turkiye) will be enrolled and followed for 12 months. Patient-reported outcomes and clinical assessments will be collected preoperatively (baseline) and postoperatively at 3 and 12 months. The primary outcomes are shoulder function (ASES), rotator cuff-related quality of life (WORC converted to a 0-100 scale), and sleep disturbance (Insomnia Severity Index). Secondary outcomes include active shoulder range of motion and biceps-related clinical findings (Speed test, Yergason test, bicipital groove tenderness, and Popeye deformity). Postoperative MRI will not be obtained routinely and will be performed only if clinically indicated. The study aims to provide standardized prospective data on functional outcomes, quality of life, and sleep after this augmentation approach.",[435],"Massive Rotator Cuff Tear",[437,435,438],"Biceps Transposition","Arthroscopic Partial Repair",{"date":440,"type":42},"2026-05-28",{"date":442,"type":42},"2026-03-26",{"date":444,"type":23},"2027-12-15",{"name":48,"class":49},{"id":447,"slug":448,"hasResults":12,"nctId":449,"briefTitle":450,"officialTitle":451,"acronym":452,"eligibilityCriteria":453,"healthyVolunteers":171,"sex":18,"minAge":19,"maxAge":366,"enrollmentInfo":454,"targetDuration":4,"studyType":24,"phases":456,"briefSummary":457,"conditions":458,"keywords":463,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":471,"lastUpdatePostDateStruct":472,"startDateStruct":473,"completionDateStruct":474,"leadSponsor":476,"locationsCount":137},"100639394","skin-to-skin-contact-and-lavender-aromatherapy-after-elective-cesarean-effects-on-cortisol-and-early-breastfeeding-100639394","NCT07612059","Skin-to-Skin Contact and Lavender Aromatherapy After Elective Cesarean: Effects on Cortisol and Early Breastfeeding","Elective Cesarean Section Postpartum Structured Mother-Infant Skin-to-Skin Contact With Maternal Lavender Aromatherapy: Effects on Maternal Salivary Cortisol, IgA Levels and Early Breastfeeding Outcomes - A Randomized Controlled Trial","LAVENDER-SSC","Inclusion Criteria:\n\n* Female participants aged 18 to 40 years\n* Term singleton pregnancy (≥37 weeks of gestation)\n* Scheduled for elective cesarean section\n* ASA physical status I-II\n* Planned spinal anesthesia\n* Clinically stable mother and newborn immediately after birth\n* Ability to initiate breastfeeding in the early postpartum period\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency cesarean section\n* General anesthesia or conversion from spinal to general anesthesia\n* Need for neonatal resuscitation or severe neonatal compromise\n* Maternal hemodynamic instability or massive hemorrhage\n* Major fetal congenital anomalies\n* Known allergy or intolerance to lavender\n* Severe asthma or intolerance to strong odors\n* Major psychiatric disorders\n* Serious endocrine diseases affecting stress hormone regulation\n* Clinical conditions that preclude breastfeeding\n* Contraindications to spinal anesthesia\n* Refusal to participate in the study",{"count":455,"type":23},150,[26],"This single-center randomized controlled clinical trial will evaluate the effects of structured early postpartum mother-infant skin-to-skin contact, with or without maternal lavender aromatherapy, after elective cesarean section on maternal stress biomarkers and early breastfeeding outcomes. The study will enroll 150 term pregnant women scheduled for elective cesarean section under spinal anesthesia at Ataturk University Research Hospital. Participants will be randomized into three groups: routine postoperative care, structured skin-to-skin contact, and structured skin-to-skin contact combined with inhalational lavender aromatherapy. The primary outcome is the change in maternal salivary cortisol level from immediately after birth to 60 minutes postpartum. Secondary outcomes include maternal salivary IgA levels, state anxiety scores, postoperative pain and nausea, time to first analgesic requirement, early breastfeeding initiation and success, LATCH scores, neonatal axillary temperature, cumulative duration and continuity of skin-to-skin contact, maternal satisfaction, and the need for mother-infant separation within the first 2 hours postpartum.",[459,460,461,462],"Breastfeeding","Cesarean Section","Postpartum Period","Maternal Stress",[464,465,466,467,468,469,470],"Elective cesarean section","Skin-to-skin contact","Lavender aromatherapy","Salivary cortisol","Immunoglobulin A (IgA)","Early breastfeeding","Postoperative pain","2026-05-21",{"date":440,"type":42},{"date":416,"type":23},{"date":475,"type":23},"2027-12-30",{"name":48,"class":49},{"id":478,"slug":479,"hasResults":12,"nctId":480,"briefTitle":481,"officialTitle":482,"acronym":4,"eligibilityCriteria":483,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":401,"enrollmentInfo":484,"targetDuration":4,"studyType":24,"phases":485,"briefSummary":486,"conditions":487,"keywords":490,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":499,"lastUpdatePostDateStruct":500,"startDateStruct":501,"completionDateStruct":503,"leadSponsor":504,"locationsCount":137},"100638726","sevoflurane-vs-propofol-anesthesia-in-obese-patients-undergoing-lumbar-surgery-100638726","NCT07611240","Sevoflurane vs Propofol Anesthesia in Obese Patients Undergoing Lumbar Surgery","Comparison of the Immunomodulatory Effects of Sevoflurane and Propofol Anesthesia on Pentraxin-3 and Serum Amyloid A Levels in Obese Patients Undergoing Lumbar Instrumentation Surgery","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* Patients scheduled for elective lumbar instrumentation surgery\n* Body mass index between 30 and 34.9 kg\u002Fm²\n* Patients who provided written informed consent\n\nExclusion Criteria:\n\n* Known allergy to inhalational or intravenous anesthetic agents\n* Acute or chronic infectious disease\n* Autoimmune disease or immunodeficiency\n* Surgery within the last 3 months\n* Chronic anti-inflammatory or immunomodulatory drug use\n* Morbid obesity, defined as BMI \\>35 kg\u002Fm²\n* History of malignancy or active cancer treatment\n* Renal failure, defined as GFR \\\u003C60 mL\u002Fmin\n* Liver failure, defined as AST or ALT greater than 2 times the upper limit of normal\n* Diabetes mellitus, metabolic syndrome, or insulin resistance\n* Pregnancy or lactation\n* Neurological disease, including epilepsy, multiple sclerosis, or Parkinson's disease\n* Alcohol or substance abuse\n* Inability to comply with the study protocol or provide informed consent\n* Known allergy to study drugs (propofol, sevoflurane, remifentanil)\n* Emergency surgery",{"count":265,"type":23},[26],"This randomized, single-center, single-masked clinical trial aims to compare the immunomodulatory effects of sevoflurane-based inhalational anesthesia and propofol-based total intravenous anesthesia in obese patients undergoing elective lumbar instrumentation surgery. Seventy patients will be randomized into two groups: a propofol group and a sevoflurane group. Blood samples will be collected preoperatively, at postoperative 6 hours, and at postoperative 24 hours. Pentraxin-3 and serum amyloid A levels will be evaluated as primary inflammatory biomarkers together with IL-6, TNF-α, CRP, glucose, and complete blood count parameters.",[488,489],"Obesity & Overweight","Lumbar Spine Surgery",[491,492,493,494,495,496,497,498],"Propofol","Sevoflurane","Pentraxin-3","Serum Amyloid A","Immunomodulation","Total Intravenous Anesthesia","Volatile Anesthesia","Inflammatory Response","2026-05-20",{"date":440,"type":42},{"date":502,"type":42},"2025-06-15",{"date":354,"type":23},{"name":48,"class":49},{"id":506,"slug":507,"hasResults":12,"nctId":508,"briefTitle":509,"officialTitle":510,"acronym":511,"eligibilityCriteria":512,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":513,"enrollmentInfo":514,"targetDuration":4,"studyType":24,"phases":516,"briefSummary":517,"conditions":518,"keywords":522,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":389,"lastUpdatePostDateStruct":532,"startDateStruct":534,"completionDateStruct":536,"leadSponsor":538,"locationsCount":137},"100612014","effect-of-ipack-and-bifes-blocks-on-quality-of-recovery-after-total-knee-arthroplasty-100612014","NCT07248072","Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty","Effects of iPACK and Biceps Femoris Short Head (BiFeS) Blocks Combined With Adductor Canal Block on Quality of Recovery After Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Clinical Trial","BiFeS-TKA","Inclusion Criteria:\n\n* Age 18-75 years\n* Scheduled for elective primary unilateral total knee arthroplasty (TKA)\n* Planned spinal anesthesia\n* ASA physical status I-III\n* Ability to understand study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to local anesthetics or other study medications\n* Coagulopathy or current anticoagulant therapy\n* Severe hepatic, renal, or cardiac failure\n* History of neuropathic pain\n* Infection at the site of proposed nerve block\n* Pre-existing neuromuscular disorders in the lower extremities\n* Inability to cooperate or refusal to participate in the study\n* Pregnancy","75 Years",{"count":515,"type":23},74,[26],"This prospective, randomized, double-blind clinical trial aims to compare the effects of two different posterior knee analgesia techniques-iPACK block (Interspace Between the Popliteal Artery and the Capsule of the posterior Knee) and the Biceps Femoris Short Head (BiFeS) block-when combined with an adductor canal block (ACB) in patients undergoing elective unilateral total knee arthroplasty (TKA). Effective postoperative analgesia is essential for early mobilization, enhanced recovery, and patient satisfaction after TKA. Although ACB provides good anterior knee analgesia while preserving quadriceps strength, additional posterior knee analgesia is often required.\n\nThe iPACK block is a commonly used technique that targets the posterior knee capsule, whereas the newer BiFeS block aims to provide more selective posterolateral sensory blockade with potentially reduced risk of motor involvement. However, comparative clinical data between these two techniques are limited.\n\nThe primary objective of this study is to evaluate the difference between the iPACK and BiFeS blocks in terms of Quality of Recovery-15 (QoR-15) scores at 24 hours postoperatively. Secondary objectives include comparisons of postoperative pain scores, opioid consumption, time to first analgesic request, quadriceps and anterior tibialis muscle strength, functional test performance, time to mobilization, active range of motion, and the incidence of adverse events.\n\nA total of 74 adult patients scheduled for elective unilateral TKA under spinal anesthesia will be randomized in a 1:1 ratio into two groups: ACB + iPACK block or ACB + BiFeS block. All blocks will be performed under ultrasound guidance by an experienced anesthesiologist. Outcome assessments will be conducted by blinded investigators. The study aims to provide high-quality clinical evidence regarding the effectiveness of the BiFeS block compared to the widely used iPACK technique.",[519,520,521],"Knee Osteoarthritis","Postoperative Pain Management","Total Knee Arthroplasty",[521,523,524,525,526,527,528,529,530,531],"Knee Replacement","Adductor Canal Block","iPACK Block","BiFeS Block","Regional Anesthesia","Postoperative Analgesia","QoR-15","Posterior Knee Pain","Ultrasound-Guided Nerve Block",{"date":533,"type":42},"2026-05-18",{"date":535,"type":42},"2025-12-01",{"date":537,"type":23},"2026-07-02",{"name":48,"class":49},{"id":540,"slug":541,"hasResults":12,"nctId":542,"briefTitle":543,"officialTitle":544,"acronym":545,"eligibilityCriteria":546,"healthyVolunteers":12,"sex":58,"minAge":19,"maxAge":401,"enrollmentInfo":547,"targetDuration":4,"studyType":24,"phases":548,"briefSummary":549,"conditions":550,"keywords":555,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":565,"lastUpdatePostDateStruct":566,"startDateStruct":568,"completionDateStruct":569,"leadSponsor":571,"locationsCount":137},"100635258","bupivacaine-lidocaine-vs-bupivacaine-for-ultrasound-guided-popliteal-sciatic-nerve-block-100635258","NCT07550348","Bupivacaine-Lidocaine vs Bupivacaine for Ultrasound-Guided Popliteal Sciatic Nerve Block","Bupivacaine-Lidocaine Combination Versus Bupivacaine Alone for Ultrasound-Guided Popliteal Sciatic Nerve Block in Elective Lower Extremity Surgery: A Prospective Randomized Double-Blind Trial","PSSNB-BL","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status classification I, II, or III\n* Scheduled for elective distal lower extremity surgery (below-knee)\n* Body mass index (BMI) between 18 and 35 kg\u002Fm²\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Morbid obesity (BMI ≥35 kg\u002Fm²)\n* Known allergy or hypersensitivity to any local anesthetic agent\n* Severe cardiac, hepatic, or renal disease\n* Pre-existing neurological deficits or peripheral neuropathy\n* Use of anticoagulant therapy\n* History of prior surgery or significant scar tissue in the popliteal fossa\n* Pregnancy\n* Chronic opioid use at home",{"count":202,"type":23},[26],"This prospective, randomized, double-blind clinical trial aims to compare the efficacy of two local anesthetic regimens for ultrasound-guided popliteal sciatic nerve block in adult patients undergoing elective distal lower extremity surgery.\n\nEligible participants (ages 18-65, ASA physical status I-III, BMI 18-35 kg\u002Fm²) will be randomized into two equal groups of 30. Patients in Group BL will receive a combination of 10 mL 2% lidocaine and 10 mL 0.5% bupivacaine, while patients in Group B will receive 20 mL 0.5% bupivacaine alone, administered via ultrasound-guided popliteal sciatic nerve block prior to surgery.\n\nThe primary outcome is the onset time of sensory and motor blockade. Secondary outcomes include block success rate, duration of sensory and motor block, postoperative opioid consumption, pain scores assessed by the Numeric Rating Scale (NRS) at 2, 4, 8, 12, and 24 hours postoperatively, Quality of Recovery-15 (QoR-15) score, and incidence of rebound pain.\n\nThe study is conducted at Ataturk University Research Hospital, Department of Anesthesiology and Reanimation, Erzurum, Turkey.",[551,552,553,554],"Lower Extremity","Nerve Block","Pain, Postoperative","Pain, Nerve",[556,557,558,559,560,561,562,563,564,529],"Popliteal sciatic nerve block","Bupivacaine","Lidocaine","Local anesthetic","Ultrasound-guided nerve block","Regional anesthesia","Postoperative analgesia","Block onset time","Lower extremity surgery","2026-05-08",{"date":567,"type":42},"2026-05-12",{"date":535,"type":42},{"date":570,"type":23},"2027-03-01",{"name":48,"class":49},{"id":573,"slug":574,"hasResults":12,"nctId":575,"briefTitle":576,"officialTitle":577,"acronym":4,"eligibilityCriteria":578,"healthyVolunteers":171,"sex":58,"minAge":19,"maxAge":4,"enrollmentInfo":579,"targetDuration":4,"studyType":24,"phases":580,"briefSummary":581,"conditions":582,"keywords":584,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":588,"lastUpdatePostDateStruct":589,"startDateStruct":591,"completionDateStruct":593,"leadSponsor":595,"locationsCount":4},"100636018","the-effect-of-escape-room-based-elimination-training-on-student-outcomes-100636018","NCT07560228","The Effect of Escape Room-Based Elimination Training on Student Outcomes","The Effect of Escape Room Games Used in Elimination Care Training on Nursing Students' Levels of Knowledge, Skills, Motivation, and Satisfaction","Inclusion Criteria:\n\n* Being a second-year student enrolled in the Nursing Department.\n* Taking the Nursing Fundamentals course for the first time.\n* Not having previously received practical training or experience in an \"Educational Escape Room.\"\n* Volunteering to participate in the study and providing written informed consent.\n* Being available to attend all training sessions (both theoretical and practical) during the study period.\n\nExclusion Criteria:\n\n* Students who are repeating the Nursing Fundamentals course.\n* Students who have transferred from another nursing program and have already completed elimination care training.\n* Students with physical disabilities or health conditions that prevent them from participating in the physical activities of the escape room.\n* Students who have professional experience as a nurse or health technician (e.g., those who graduated from vocational health high schools and worked in the field).\n* Students who do not complete the initial theoretical training or miss the pre-test assessments.",{"count":202,"type":23},[26],"This clinical trial aims to find out if playing an \"educational escape room\" game helps nursing students better learn how to manage patient elimination (urinary and bowel care). The study looks at how this game affects students' knowledge, hands-on skills, their desire to learn (motivation), and how happy they are with the training (satisfaction).\n\nThe main questions the researchers want to answer are:\n\nDoes the escape room game help students understand the rules and steps of elimination care better than traditional lessons?\n\nDoes this method improve students' practical skills in tasks like inserting catheters, giving enemas, and performing stoma care?\n\nHow does the game affect students' motivation to learn and their overall satisfaction with the nursing program?\n\nResearchers will compare students who use the educational escape room with students who learn through traditional methods to see if the game makes a real difference in their performance.\n\nParticipants in this study will:\n\nLearn the theory behind bowel and bladder care (such as enemas and catheterization).\n\nWork in small groups to solve puzzles and find clues inside a themed room to complete patient care tasks.\n\nTake knowledge tests and practical \"skill exams\" after the training.\n\nFill out surveys about how motivated they felt and how much they enjoyed the learning experience.",[583],"Student Education",[585,586,587],"NURSING","ESCAPE ROOM","EDUCATION","2026-04-24",{"date":590,"type":42},"2026-05-01",{"date":592,"type":23},"2026-04-27",{"date":594,"type":23},"2026-12-31",{"name":48,"class":49},{"id":597,"slug":598,"hasResults":12,"nctId":599,"briefTitle":600,"officialTitle":601,"acronym":4,"eligibilityCriteria":602,"healthyVolunteers":171,"sex":58,"minAge":603,"maxAge":604,"enrollmentInfo":605,"targetDuration":4,"studyType":203,"phases":4,"briefSummary":607,"conditions":608,"keywords":612,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":620,"lastUpdatePostDateStruct":621,"startDateStruct":622,"completionDateStruct":624,"leadSponsor":625,"locationsCount":137},"100635291","serum-cholinesterases-paraoxonase-and-cardiovascular-risk-after-intravitreal-bevacizumab-100635291","NCT07550777","Serum Cholinesterases, Paraoxonase, and Cardiovascular Risk After Intravitreal Bevacizumab","Serum Acetylcholinesterase, Butyrylcholinesterase, Paraoxonase Activity, and Cardiovascular Risk Factors in Patients Treated With Intravitreal Bevacizumab","Inclusion Criteria:\n\n* Age ≥ 55 years.\n* Ability to provide written informed consent.\n* Patient group: Diagnosis of macular edema secondary to diabetic retinopathy, retinal vein occlusion, or age-related macular degeneration, and having received repeated intravitreal bevacizumab injections (≥2 doses).\n* Control group: Healthy volunteers with no ocular pathology other than cataracts and not receiving intravitreal anti-VEGF treatment.\n\nExclusion Criteria:\n\n* Chronic inflammatory disease.\n* Chronic infectious disease.\n* History of cardiovascular disease (e.g., coronary artery disease, heart failure, arrhythmia requiring treatment).\n* History of cerebrovascular disease (e.g., stroke, transient ischemic attack).\n* Any additional ocular pathology that may affect the study outcomes (other than the index retinal condition in the patient group and cataract in the control group), such as:\n\nglaucoma\n\nuveitis\n\nretinal dystrophies\n\nsignificant media opacity preventing adequate ocular evaluation\n\n\\- Use of systemic medications or conditions known to affect cholinesterase activity markedly","50 Years","80 Years",{"count":606,"type":23},180,"Bevacizumab, an anti-VEGF (vascular endothelial growth factor) agent used in the treatment of diabetic retinopathy and macular edema associated with retinal vein occlusion, is commonly administered in ophthalmology clinics through intravitreal injection. The systemic use of bevacizumab has been associated with serious conditions such as thromboembolism and bleeding. Although intravitreal bevacizumab is administered in smaller amounts and has limited systemic circulation, it requires repeated injections over a long period. These long-term intravitreal anti-VEGF therapies may lead to adverse outcomes, particularly thromboembolism, due to systemic inhibition of VEGF. However, limited information is available regarding the potential effects of this treatment on the systemic and cardiovascular systems. To evaluate this risk, the study aims to assess changes in the activities of paraoxonase 1 (PON1), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE), which are closely associated with lipid metabolism, coronary artery disease, and atherosclerosis. These enzymes are known biomarkers of cardiovascular health and play significant roles in protection against oxidative stress and inflammation. For this purpose, a case-control study is planned. Serum BChE and PON1 activities, as well as triglyceride (TG)\u002Fhigh-density lipoprotein (HDL) and TG\u002Fglucose ratios, will be determined in patients receiving repeated intravitreal bevacizumab injections and in control groups, and cardiovascular disease risk will be assessed. This study may help us better understand the safety profile of this treatment by revealing the effects of bevacizumab on serum enzyme activities and cardiovascular risk factors. These findings could contribute to optimizing treatment strategies in clinical practice.",[609,610,611],"Diabete Mellitus","Retina Vein Occlusion","Age Macular Degeneration",[613,614,615,616,617,618,619],"bevacizumab","paraoxonase","retinal vein occlusion","age-related macular degeneration","diabetic retinopathy","acetylcholinesterase","butyrylcholinesterase","2026-04-22",{"date":588,"type":42},{"date":623,"type":42},"2025-11-03",{"date":186,"type":23},{"name":48,"class":49},{"id":627,"slug":628,"hasResults":12,"nctId":629,"briefTitle":630,"officialTitle":631,"acronym":4,"eligibilityCriteria":632,"healthyVolunteers":171,"sex":58,"minAge":19,"maxAge":401,"enrollmentInfo":633,"targetDuration":4,"studyType":24,"phases":634,"briefSummary":635,"conditions":636,"keywords":639,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":646,"lastUpdatePostDateStruct":647,"startDateStruct":649,"completionDateStruct":650,"leadSponsor":652,"locationsCount":137},"100632811","bulk-fill-composite-restorations-clinical-evaluation-100632811","NCT07518537","Bulk-Fill Composite Restorations: Clinical Evaluation","Clinical Evaluation of Restorations Performed With Bulk-Fill Composites of Different Technologies According to FDI Criteria: A Randomized Controlled Clinical Follow-Up Study","Inclusion Criteria:\n\n* Patients aged 18 years and older\n* Patients in good general health (systemically healthy)\n* Patients with good oral hygiene\n* Patients with good periodontal health\n* Presence of at least one posterior tooth requiring restoration\n* Teeth must be vital and asymptomatic\n* Teeth must have proximal contact with adjacent teeth on both mesial and distal surfaces\n* Teeth must be in functional occlusion with an antagonist tooth\n* Presence of at least one carious lesion not extending deeper than two-thirds of dentin, with a clinical ICDAS code ≤ 3\n* Absence of periapical pathology confirmed by radiographic evaluation\n* Patients who voluntarily agree to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Presence of any systemic disease\n* Poor oral hygiene\n* Presence of active or severe periodontal disease\n* Teeth with previous restorations or endodontic treatment\n* Non-vital (devitalized) or symptomatic teeth\n* Patients who are pregnant or breastfeeding\n* Patients undergoing active orthodontic treatment\n* Presence of parafunctional habits (e.g., bruxism) or xerostomia\n* Current tobacco use or history of heavy smoking\n* Patients unwilling or unable to attend follow-up visits",{"count":265,"type":23},[26],"This randomized controlled clinical study aims to evaluate the clinical performance of five different bulk-fill composite materials representing distinct technological approaches according to the World Dental Federation (FDI) criteria. The materials include a thermoviscous bulk-fill composite applied with preheating, a sonic-activated bulk-fill composite, a flowable bulk-fill composite, an ORMOCER-based bulk-fill composite, and a conventional bulk-fill composite. Restorations will be clinically assessed at baseline, 1 month, 6 months, and 12 months for esthetic, functional, and biological outcomes.",[637,638],"Composite Resins","Dental Caries Class II",[640,641,642,637,643,644,645],"FDI Criteria","Clinical Evaluation","Bulkfill","Thermoviscous","Sonicfill","Clinical Trial","2026-04-07",{"date":648,"type":42},"2026-04-08",{"date":499,"type":23},{"date":651,"type":23},"2027-07-20",{"name":48,"class":49},{"id":654,"slug":655,"hasResults":12,"nctId":656,"briefTitle":657,"officialTitle":658,"acronym":4,"eligibilityCriteria":659,"healthyVolunteers":171,"sex":229,"minAge":19,"maxAge":401,"enrollmentInfo":660,"targetDuration":4,"studyType":24,"phases":662,"briefSummary":663,"conditions":664,"keywords":668,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":646,"lastUpdatePostDateStruct":677,"startDateStruct":679,"completionDateStruct":681,"leadSponsor":683,"locationsCount":4},"100611482","creative-drama-on-gender-role-stress-attitudes-toward-violence-against-women-and-aggression-100611482","NCT07241156","Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression","Determining the Impact of Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression Among Men Affected by an Earthquake:A Randomized Controlled Trial","Inclusion Criteria:\n\nMale individuals who experienced the 2023 Türkiye earthquake (centered in Kahramanmaraş) and currently live in Malatya.\n\nMarried during the earthquake and currently married.\n\nVolunteer to participate in the study.\n\nAged between 18 and 65 years.\n\nNo hearing or visual impairments.\n\nNo intellectual disability.\n\nAt least primary school graduate.\n\nNo diagnosed psychiatric disorder.\n\nHave not received creative drama training.\n\nHave not received psychosocial support after the earthquake.\n\nHave not participated in previous studies involving creative drama related to gender role stress, attitudes toward violence against women, or aggression.\n\nAgree to attend weekly sessions and comply with the study program.\n\nExclusion Criteria:\n\nVoluntary withdrawal from the study.\n\nFailure to attend sessions regularly.\n\nChanging residence to another city during the study period.\n\nDivorce during the study period.\n\nBeginning to receive psychosocial support during the study period.",{"count":661,"type":23},75,[26],"This study aims to examine the effect of Creative Drama on gender role stress, attitudes toward violence against women, and aggression among men who experienced the February 6, 2023 earthquake in Türkiye (centered in Kahramanmaraş).\n\nA total of 75 men (25 experimental, 25 placebo, and 25 control) will participate in the study. The experimental group will take part in a creative drama program, the placebo group will watch films focusing on masculinity roles and violence for 10 weeks, and no intervention will be applied to the control group.\n\nData will be collected using the Gender Role Stress Scale for Men, the Attitudes Toward Violence Against Women Scale, and the Buss-Perry Aggression Questionnaire - Short Form, and will be analyzed by an independent statistician.\n\nThe study aims to enhance the psychological well-being of men affected by the earthquake in Türkiye, reduce violence against women, and contribute to gender equality.",[665,666,667],"Gender Role","Aggression","Violence",[669,670,671,672,673,674,675,676],"Creative Drama","Gender Role Stress","Attitudes Toward Violence Against Women","Earthquake Survivors","Men's Mental Health","Post-Disaster Psychosocial Support","Türkiye Earthquake 2023","Non-Pharmacological Intervention",{"date":678,"type":42},"2026-04-09",{"date":680,"type":23},"2026-03-30",{"date":682,"type":23},"2026-12-30",{"name":48,"class":49},{"id":685,"slug":686,"hasResults":12,"nctId":687,"briefTitle":688,"officialTitle":689,"acronym":4,"eligibilityCriteria":690,"healthyVolunteers":171,"sex":58,"minAge":691,"maxAge":692,"enrollmentInfo":693,"targetDuration":4,"studyType":24,"phases":694,"briefSummary":695,"conditions":696,"keywords":699,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":646,"lastUpdatePostDateStruct":703,"startDateStruct":705,"completionDateStruct":707,"leadSponsor":709,"locationsCount":710},"100592397","the-effect-of-hologram-application-on-pain-anxiety-and-fear-levels-in-children-during-burn-dressing-100592397","NCT06992895","The Effect of Hologram Application on Pain, Anxiety, and Fear Levels in Children During Burn Dressing","Effect of Hologram Application on Pain, Anxiety and Fear Levels During Burn Dressing in Children: A Randomized Controlled Trial","Inclusion Criteria:\n\n* The subject has indicated their willingness to participate in the study. Physical and mental health.\n* The age range of the subjects included in this study was from 3 to 12 years of age.\n* The subject had never previously engaged in the practice of dressing a burn.\n* The presence of only second degree burns\n* Burn percentage is under 10%\n\nExclusion Criteria:\n\n* The subject is unwilling or unable to provide informed consent or assent (if applicable).\n* The subject has a history of significant physical or mental health disorders that may interfere with participation in the study.\n* The subject is younger than 3 years old or older than 12 years old.\n* The subject has previously engaged in the practice of burn dressing or similar procedures.\n* The presence of burns other than second-degree burns (e.g., first-degree or third-degree burns).\n* The percentage of burn area is greater than 10%.","3 Years","12 Years",{"count":265,"type":23},[26],"The process of dressing burn injuries has been shown to cause both physical and psychological difficulties. In children, this process is particularly associated with intense pain and anxiety. Consequently, in addition to pharmacological interventions, non-pharmacological methods such as distraction are employed. In recent years, the utilization of holograms as a method of alleviating pain has emerged as a novel approach. The employment of these visual illusions has been demonstrated to effectively distract children, thereby providing a means of reducing discomfort. The objective of this thesis is to evaluate the effects of hologram application on pain, anxiety, fear, and vital signs during burn dressing in children.",[697,698],"Burn Wounds","Burn",[700,701,702,239,240],"Holography","Burns","Pain",{"date":704,"type":42},"2026-04-13",{"date":706,"type":42},"2025-10-15",{"date":708,"type":23},"2026-06-20",{"name":48,"class":49},2,{"id":712,"slug":713,"hasResults":12,"nctId":714,"briefTitle":715,"officialTitle":716,"acronym":4,"eligibilityCriteria":717,"healthyVolunteers":171,"sex":18,"minAge":19,"maxAge":718,"enrollmentInfo":719,"targetDuration":4,"studyType":24,"phases":720,"briefSummary":721,"conditions":722,"keywords":724,"overallStatus":248,"whyStopped":4,"lastUpdateSubmitDate":729,"lastUpdatePostDateStruct":730,"startDateStruct":731,"completionDateStruct":733,"leadSponsor":734,"locationsCount":137},"100632504","investigation-of-the-effect-of-video-assisted-laughter-yoga-100632504","NCT07514546","Investigation of The Effect of Video-Assisted Laughter Yoga","Investigation of The Effect of Video-Assisted Laughter Yoga on Pain and Menstrual Symptoms in Primary Dysmenorrhea","Inclusion Criteria:\n\n* Students with regular menstrual periods (lasting 3-8 days, with a menstrual cycle range of 21-35 days)\n* Students with dysmenorrhea pain intensity of 45 mm or more according to the Visual Analog Scale (VAS).\n\nExclusion Criteria:\n\n* Students diagnosed with secondary dysmenorrhea (endometriosis, ovarian cyst\u002Ftumor, pelvic infectious disease, myoma, uterine polyps, uterine adhesions, infection, etc.),\n* those using oral contraceptives,\n* those with compromised tissue integrity in the abdominal area,\n* those with any chronic or mental illness.","24 Years",{"count":146,"type":23},[26],"This study is planned to examine the effect of video-assisted laughter yoga on pain and menstrual symptoms among students studying at a university in Türkiye. Data will be collected at the Faculty of Health Sciences, Konya Karatay University, between November 2025 and April 2026. The study population will consist of students aged 18 to 24 years studying at the Faculty of Health Sciences during the specified period. The sample size was calculated using the G Power computer program. Using a power analysis at the α=0.05 level, the effect size was calculated as 150, 153 (d=0.8), and the working power was calculated as 90%, indicating that at least 68 students should be included in the sample. Students meeting the research criteria and agreeing to participate in the study will be randomly assigned to an experimental group and a control group. The socio-demographic data of the students in the Faculty of Health Sciences, the Visual Analog Scale to assess students' pain, and the Menstrual Symptom Scale to measure menstrual symptoms, prepared by the researcher in accordance with the literature, will be used.",[723],"Laughter Yoga",[725,726,727,728,723],"Primary dysmenorrhea","menstrual symptoms","Video","pain","2026-03-31",{"date":646,"type":42},{"date":732,"type":42},"2024-12-30",{"date":620,"type":23},{"name":48,"class":49},""]