[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Avicenna Military Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100600345","the-pvco2-paco2cao2-cvo2-ratio-in-septic-shock-100600345",false,"NCT07096284","The PvCO2-PaCO2\u002FCaO2-CvO2 Ratio in Septic Shock","Prognostic Value and Kinetics of the PvCO2-PaCO2\u002FCaO2-CvO2 Ratio Compared to Arterial Lactate in the Initial Phase of Septic Shock","SepsisO2CO2R","Inclusion Criteria:\n\nPatients aged over 18 years presenting with septic shock, defined as sepsis with persistent hypotension requiring vasopressors to maintain a mean arterial pressure (MAP) ≥ 65 mmHg and lactatemia \\> 2 mmol\u002FL despite adequate fluid resuscitation. Sepsis is defined by the presence of a suspected or confirmed infectious source associated with organ dysfunction (neurological, respiratory, renal, hepatic, or hematological). \\[Sepsis 3 criteria\\]\n\nExclusion Criteria:\n\n* Absence of central venous access.\n* Central venous access not positioned in the superior vena cava (e.g., femoral access).","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","OBSERVATIONAL","The ratio of the venous-arterial carbon dioxide partial pressure difference to the arteriovenous oxygen content difference (Pv-aCO₂\u002FCa-vO₂) may be a marker of anaerobic metabolism in patients with acute circulatory failure. This study aims to assess the prognostic value of the PvCO2-PaCO2\u002FCaO2-CvO2 in the early phase of septic shock.",[25],"Septic Shock",[27,28],"sepsis","anaerobic metabolism","RECRUITING","2026-03-28",{"date":32,"type":33},"2026-03-31","ACTUAL",{"date":35,"type":33},"2025-01-05",{"date":37,"type":21},"2026-06-30",{"name":39,"class":40},"Avicenna Military Hospital","OTHER",3,""]