[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"BILLOIR\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100468151","study-of-erythrocyte-parameters-and-hypercoagulability-in-sickle-cell-disease-scd-tga-100468151",false,"NCT05376046","Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA)","Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease","SCD-TGA","Inclusion Criteria:\n\n* Sickle cell disease\n\nExclusion Criteria:\n\n* \\\u003C18 years\n* pregnancy\n* Patient under protective guardianship or curatorship",true,"ALL","18 Years",{"count":21,"type":22},200,"ESTIMATED","5 Years","OBSERVATIONAL","Sickle cell disease (SCD) is an inherited haemoglobinopathy disorder caused by mutations in HBB gene with amino-acid substitution on β globin chain. The consequence is synthesis of altered haemoglobin S (HbS) which polymerises in red blood cell (RBC) at deoxygenated state. SCD is associated with chronic haemolytic anaemia, vaso-occlusive crisis (VOC) leading to frequent hospitalisation.\n\nThe aim of the study was to to investigate whether a combination of routine laboratory biomarkers of haemolysis could be used to predict VOC development in confirmed SCD patients.",[27,28],"Sickle Cell Disease","Vaso-occlusive Crisis",[30,31,32,33,34],"sickle cell disease","vaso-occlusive crisis","reticulocyte count","thrombin generation assay","hypercoagulability","RECRUITING","2022-05-17",{"date":38,"type":39},"2022-05-24","ACTUAL",{"date":41,"type":39},"2018-09-01",{"date":43,"type":22},"2026-09-01",{"name":45,"class":46},"BILLOIR","OTHER",""]