[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Başakşehir Çam & Sakura City Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":698},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,27,0,25,[9,48,77,109,141,173,203,230,258,287,308,346,373,399,425,451,478,508,531,554,574,595,622,651,674],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":24,"studyType":25,"phases":4,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100607911","effect-of-operating-room-noise-on-bis-and-hemodynamics-under-general-anesthesia-100607911",false,"NCT07194707","Effect of Operating Room Noise on BIS and Hemodynamics Under General Anesthesia","The Effect of Operating Room Environmental Noise on BIS and Hemodynamics in Patients Under General Anesthesia: A Prospective Observational Study","Inclusion Criteria:\n\n* Adults aged 18-70\n* ASA (American Society of Anesthesiologists) physical status score I-II\n* Scheduled for elective surgery\n* To be undergoing general anesthesia\n* Having signed the informed consent form to participate in the study\n\nExclusion Criteria:\n\n* Hearing impairment or ear pathology\n* History of neurological disease (epilepsy, stroke, dementia, etc.)\n* Use of psychiatric medications (anxiolytics, antidepressants, antipsychotics, etc.)\n* Indications for emergency surgery\n* Planned spinal or epidural anesthesia\n* Conditions unsuitable for BIS monitoring\n* Cognitive impairment preventing informed consent",true,"ALL","18 Years","70 Years",{"count":22,"type":23},70,"ESTIMATED","1 Day","OBSERVATIONAL","This prospective observational study aims to evaluate the impact of operating room noise on bispectral index (BIS) and hemodynamic parameters in patients undergoing general anesthesia. Environmental noise in operating rooms, often overlooked, may influence anesthesia depth, patient safety, and physiological stability. A total of 70 adult patients (ASA I-II, 18-65 years, elective surgery under general anesthesia) will be enrolled at Başakşehir Çam and Sakura City Hospital. Patients will be categorized into two groups based on intraoperative average noise levels: noisy group (\\>65 dB) and quiet group (\\\u003C55 dB). Noise levels will be measured every 10 minutes using a CEM DT-8850 sound level meter, BIS will be recorded every 10 minutes, and hemodynamic variables (systolic, diastolic, mean arterial pressure, and heart rate) will be recorded every 5 minutes.\n\nPrimary outcome is the correlation between mean intraoperative noise levels (LAeq) and BIS values during the maintenance phase of anesthesia. Secondary outcomes include the relationship between noise characteristics (e.g., device-related, human-related, alarms, media) and hemodynamic stability, as well as surgical branch-related noise classifications (high, moderate, low). The study is non-interventional, with no additional risk to participants beyond standard clinical monitoring. Findings are expected to provide evidence on the role of environmental noise in anesthesia quality, inform operating room organization, and contribute to patient safety improvements.",[28,29,30],"General Anesthesia","Hemodynamics","Noise Exposure",[32,33,34,29,35,30],"Anesthesia, General","Operating Rooms","Monitoring, Intraoperative","Bispectral Index (BIS)","NOT_YET_RECRUITING","2026-07-21",{"date":39,"type":40},"2026-07-22","ACTUAL",{"date":42,"type":23},"2026-08-01",{"date":44,"type":23},"2026-12-01",{"name":46,"class":47},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":56,"targetDuration":58,"studyType":25,"phases":4,"briefSummary":59,"conditions":60,"keywords":66,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":70,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},"100584073","determination-of-the-frequency-and-predictors-of-difficult-intubation-in-septoplasty-operations-100584073","NCT06884592","Determination of the Frequency and Predictors of Difficult Intubation in Septoplasty Operations","Determination of the Incidence of Difficult Intubation and Predictive Factors in Patients Undergoing Nasal Septum Deviation Surgery.","Inclusion Criteria:\n\n* Consenting patients,\n* ASA-I-II\n* Between the ages of 18 and 65,\n* Difficult intubation and no history of facial trauma or congenital craniofacial deformity\n* Patients with easy mask ventilation during the procedure\n* Nasal obstruction due to deviated nasal septum,\n* Patients who will receive general anaesthesia and undergo septoplasty surgery\n\nExclusion Criteria:\n\n* Patients without consent\n* Not in the appropriate age range,\n* Patients who do not receive general anaesthesia and will not undergo septoplasty surgery,\n* ASA-IV-V with ,\n* Difficult intubation and a history of facial trauma or congenital craniofacial deformity\n* Patients with easy mask ventilation during the procedure","65 Years",{"count":57,"type":23},300,"2 Days","Deviated septum is among the most prevalent etiologies of nasal obstruction. Congenital or acquired deformities of the nasal septum have been demonstrated to result in partial obstruction of the airflow, thereby causing respiratory distress. Furthermore, studies have indicated a potential correlation between nasal congestion and Obstructive Sleep Apnoea Syndrome (OSAS). It is a well-documented phenomenon that patients suffering from nasal obstruction often exhibit an open mouth during sleep, a condition that has been shown to result in the narrowing of the pharyngeal lumen and the subsequent development of sleep-related breathing disorders, including snoring and sleep apnoea. Surgical intervention to correct a deviated nasal septum (commonly referred to as septoplasty) has been shown to reduce upper airway resistance by enhancing airflow, leading to a reduction in the severity of both snoring and OSAS. Numerous studies have demonstrated a robust correlation between a deviated nasal septum and asymmetric facial growth, including maxillary and mandibular abnormalities. While septoplasty is considered a minor surgical procedure with a low anaesthetic risk, concomitant obstructive sleep apnoea syndrome (OSAS) and facial asymmetry have been demonstrated to be associated with an increased risk of difficult intubation. Consequently, the development of preoperative assessment tests to predict difficult intubation is imperative for effective planning of the necessary preoperative preparation when such complications are anticipated. The present study therefore sought to evaluate the incidence of difficult airway in patients undergoing septoplasty. The secondary aim was to determine the predictive factors associated with difficult airway in patients undergoing septoplasty.",[61,62,63,64,65],"Nasal Septum, Irregular","Nasal Septal Defect","Difficult Airway","Difficult Endotracheal Intubation","Predicted Difficult Airway",[67,68,63,65],"Septoplasty","Nasal Septum Deviation","RECRUITING",{"date":39,"type":40},{"date":72,"type":40},"2025-05-28",{"date":74,"type":23},"2027-01-30",{"name":46,"class":47},1,{"id":78,"slug":79,"hasResults":12,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":12,"sex":84,"minAge":19,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":96,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":4},"100647468","pretibial-tens-for-pain-and-anxiety-during-intravesical-onabotulinumtoxina-injection-100647468","NCT07707791","Pretibial TENS for Pain and Anxiety During Intravesical OnabotulinumtoxinA Injection","The Effect of Pretibial Transcutaneous Electrical Nerve Stimulation (TENS) on Pain and Anxiety During Intravesical OnabotulinumtoxinA Injection: A Double-Blind, Randomized, Placebo-Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of overactive bladder (OAB) with an indication for intravesical onabotulinumtoxinA (BTX-A) treatment\n* No previous history of TENS application\n* Age 18 years or older\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Presence of a cardiac pacemaker or any implanted neuromodulator device\n* Impaired skin integrity in the pretibial region or peripheral neuropathy\n* Pregnancy\n* Coagulopathy that contraindicates the procedure, or active urinary tract infection","FEMALE",{"count":86,"type":23},68,"INTERVENTIONAL",[89],"NA","Overactive bladder is a common condition that causes a frequent, urgent need to urinate and can significantly reduce quality of life. When other treatments do not work well enough, doctors can inject a medication called onabotulinumtoxinA (a form of botulinum toxin) into the bladder wall. This procedure is often done in the office and is effective, but it can cause pain and anxiety during the injection.\n\nTranscutaneous electrical nerve stimulation (TENS) is a non-invasive, drug-free method that uses mild electrical pulses delivered through pads placed on the skin. It is thought to reduce the sensation of pain and is already used to help with discomfort during some office procedures.\n\nThe purpose of this study is to find out whether applying TENS to the front of the lower legs (the pretibial area) reduces pain and anxiety in patients undergoing an intravesical onabotulinumtoxinA injection. Participants will be randomly assigned to one of two groups. In one group, the TENS device will be turned on (active). In the other group, the pads will be placed in the same location but the device will not be turned on (placebo). Neither the patient nor the doctor performing the assessment will know which group the patient is in.\n\nPain will be measured during the procedure using a visual analog scale. Anxiety will be measured before the procedure using a standard questionnaire, and patient satisfaction will be measured afterward. The study aims to enroll 68 participants in total.",[92,93,94,95],"Overactive Bladder (OAB)","Botulinum Toxin Injection","Procedural Pain Relief","Anxiety",[97,98,99,100],"Transcutaneous Electrical Nerve Stimulation","Intravesical Injection","Overactive Bladder","Procedural Pain","2026-07-13",{"date":103,"type":40},"2026-07-16",{"date":105,"type":23},"2026-07-20",{"date":107,"type":23},"2027-03-10",{"name":46,"class":47},{"id":110,"slug":111,"hasResults":12,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":12,"sex":18,"minAge":117,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":87,"phases":121,"briefSummary":122,"conditions":123,"keywords":127,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":76},"100646884","virtual-reality-assisted-cast-application-in-children-with-forearm-fractures-100646884","NCT07683715","Virtual Reality-Assisted Cast Application in Children With Forearm Fractures","Does Virtual Reality Reduce Pain, Anxiety, Physiologic Stress, and Return-Visit Fear During Pediatric Forearm Casting? A Randomized Controlled Trial","VR-CAST","Inclusion Criteria:\n\n* Children aged 4 to 15 years.\n* Diagnosis of an isolated forearm fracture requiring cast application with traction (greenstick injuries plastic deformation if NOT over 20 degrees bayonet apposition ok if \\\u003C10 years and growth remains)\n* First cast application for the current fracture episode.\n* Typically developing children without a known developmental delay or cognitive impairment that would prevent participation in the study assessments.\n* Ability of the child to understand age-appropriate instructions and respond to pain, anxiety, and fear-related assessments with caregiver assistance when necessary.\n* At least one upper extremity free of immobilization, allowing heart rate assessment during the procedure.\n* Parent or legal guardian able to provide written informed consent.\n* Child assent when appropriate according to age and local ethics committee requirements.\n* Ability and willingness of the child and caregiver to attend an approximately 30-minute blinded child psychiatry assessment 1 day after cast application.\n\nExclusion Criteria:\n\n* Open forearm fracture.\n* Multiple trauma or an additional painful injury that may affect pain, anxiety, or fear assessment.\n* Need for emergency surgery, procedural sedation, or general anesthesia during cast application.\n* Previous participation in this study.\n* Known developmental delay, cognitive impairment, autism spectrum disorder with inability to complete study assessments, or severe psychiatric disorder that may interfere with questionnaire-based evaluation.\n* Known epilepsy, photosensitive seizure disorder, severe motion sickness, vestibular disorder, or any condition considered unsafe for VR headset use.\n* Visual or hearing impairment preventing use of the VR intervention or completion of the assessments.\n* Head, face, or scalp injury preventing safe or comfortable use of a VR headset.\n* Nausea, dizziness, or severe discomfort before the procedure that would prevent VR use.\n* Refusal of the child or caregiver to participate.\n* Inability to complete the 1-day child psychiatry follow-up assessment.","4 Years","15 Years",{"count":120,"type":23},120,[89],"This prospective randomized controlled trial will evaluate whether virtual reality can reduce procedural distress in children undergoing cast application for forearm fractures. Children will be assigned to either a virtual reality group or a standard care group. In the virtual reality group, children will watch a 3-minute child-friendly animated educational video using a VR headset during cast application. The video explains the casting procedure, how to protect the cast, and what the child should do after the cast is applied.\n\nThe study will compare pain, anxiety, heart rate response, caregiver anxiety, and procedure-related fear between the two groups. The casting team will assess the child during the procedure. One day after cast application, each child will undergo an approximately 30-minute evaluation by a child psychiatry clinician who is blinded to group allocation. This follow-up assessment will evaluate the child's current anxiety, anxiety related to the cast experience, fear of returning to the hospital or doctor, and fear-related behaviors after the procedure.",[124,125,126],"Forearm Fractures","Procedural Anxiety","Doctor-Related Fear",[128,129,130,131,132],"Virtual Reality","Pediatric Forearm Fracture","Cast Application","Procedural Distress","Educational Animation","2026-07-01",{"date":135,"type":40},"2026-07-06",{"date":137,"type":40},"2025-12-05",{"date":139,"type":23},"2026-09-01",{"name":46,"class":47},{"id":142,"slug":143,"hasResults":12,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":87,"phases":152,"briefSummary":153,"conditions":154,"keywords":156,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":76},"100644958","comparison-of-three-analgesic-strategies-for-hip-fracture-surgery-100644958","NCT07676734","Comparison of Three Analgesic Strategies for Hip Fracture Surgery","Comparison of the Postoperative Analgesic Efficacy of Quadro-Iliac Plane Block, Suprainguinal Fascia Iliaca Block, and Standard Analgesia Protocol in Patients Undergoing Hip Fracture Surgery Under Spinal Anesthesia: A Prospective, Randomized, Double-Blind, Controlled Trial","HIP-3B","Inclusion Criteria:\n\n* Adult patients aged 18 years or older\n* Patients scheduled for hip fracture surgery under spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Contraindications to spinal anesthesia\n* Contraindications to regional anesthesia\n* Allergy to local anesthetics or study medications\n* Infection at the injection site\n* Coagulopathy or anticoagulant therapy precluding regional block\n* Cognitive impairment preventing pain assessment\n* Chronic opioid use\n* Revision surgery","85 Years",{"count":151,"type":23},90,[89],"Hip fracture surgery is associated with significant postoperative pain and increased opioid requirements. Regional anesthesia techniques may improve analgesia and reduce opioid consumption. This prospective, randomized, double-blind, controlled trial aims to compare the postoperative analgesic efficacy of Quadro-Iliac Plane Block (QIPB), Suprainguinal Fascia Iliaca Block (SIFIB), and standard analgesia in patients undergoing hip fracture surgery under spinal anesthesia. The primary outcome is cumulative tramadol consumption during the first 24 postoperative hours. Secondary outcome measures include postoperative pain intensity, rescue analgesic requirement, incidence of postoperative nausea and vomiting, Quality of Recovery-15 (QoR-15) score, and patient satisfaction score.",[155],"Hip Fracture",[157,158,159,160,161,162,163,164],"Quadro-Iliac Plane Block","Suprainguinal Fascia Iliaca Block","Regional Anesthesia","Postoperative Analgesia","Spinal Anesthesia","Tramadol Consumption","QoR-15","Hip Fracture Surgery","2026-06-27",{"date":167,"type":40},"2026-06-30",{"date":169,"type":23},"2026-07-15",{"date":171,"type":23},"2027-02",{"name":46,"class":47},{"id":174,"slug":175,"hasResults":12,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":12,"sex":18,"minAge":55,"maxAge":4,"enrollmentInfo":180,"targetDuration":182,"studyType":25,"phases":4,"briefSummary":183,"conditions":184,"keywords":188,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":202,"locationsCount":76},"100642976","the-relationship-between-preoperative-anxiety-level-and-frailty-score-in-elderly-patients-scheduled-for-elective-hip-arthroplasty-a-prospective-observational-study-100642976","NCT07633483","The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study","Assessment of the Relationship Between Preoperative Anxiety Level Measured by the Hamilton Anxiety Rating Scale and Frailty Score Assessed by the FRAIL Scale in Elderly Patients Aged 65 Years and Older Scheduled for Elective Hip Arthroplasty: A Prospective Observational Single-Center Study","Inclusion Criteria:\n\n* Patients of both sexes aged 65 years and older\n* Patients with ASA physical status classification I, II, or III scheduled for elective hip arthroplasty\n* Patients who voluntarily agree to participate in the study\n* Patients with intact orientation and sufficient cooperation for assessment\n\nExclusion Criteria:\n\n* Patients with ASA physical status classification IV or V\n* Patients who refuse to participate in the study\n* Patients with impaired orientation or insufficient cooperation for assessment\n* Patients scheduled for emergency surgery\n* Patients to be operated during an active intensive care unit admission",{"count":181,"type":23},142,"1 Week","Frailty is a state of vulnerability resulting from decreased physiological reserve across multiple organ systems, impairing an individual's ability to withstand stressors. As the elderly population grows worldwide, the proportion of older adults undergoing surgical procedures continues to rise, and frailty is expected to become increasingly prevalent among surgical candidates.\n\nAnxiety is one of the most common psychiatric conditions, affecting approximately one in three individuals globally. Preoperative anxiety may negatively influence surgical outcomes, particularly in older and more vulnerable patients.\n\nThis prospective observational study aims to evaluate the relationship between preoperative anxiety level and frailty score in elderly patients aged 65 years and older scheduled for elective hip arthroplasty. Frailty will be assessed using the FRAIL Scale (Fatigue, Resistance, Ambulation, Illness, Loss of Weight), and anxiety will be measured using the Hamilton Anxiety Rating Scale (HAM-A). Secondary outcomes include the prevalence of frailty and anxiety, the effect of frailty on length of hospital stay, postoperative intensive care unit admission rates, and the relationship between frailty and preoperative laboratory and hemodynamic parameters.",[185,186,187],"Fraility","Anxiety, Preoperative","Hip Arthroplasty",[185,189,190,191,187,192,193,194,195],"FRAIL Scale","Preoperative Anxiety","Hamilton Anxiety Rating Scale","Elderly","Geriatric","Observational Study","Anesthesiology","2026-06-04",{"date":198,"type":40},"2026-06-08",{"date":200,"type":40},"2024-12-01",{"date":133,"type":23},{"name":46,"class":47},{"id":204,"slug":205,"hasResults":12,"nctId":206,"briefTitle":207,"officialTitle":208,"acronym":4,"eligibilityCriteria":209,"healthyVolunteers":17,"sex":210,"minAge":19,"maxAge":211,"enrollmentInfo":212,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":214,"conditions":215,"keywords":218,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":76},"100639219","effect-of-prostatic-urethra-and-seminal-vesicle-morphometry-on-ejaculation-100639219","NCT07614854","Effect of Prostatic Urethra and Seminal Vesicle Morphometry on Ejaculation","The Effect of Prostatic Urethral and Seminal Vesicle Morphometry on Multiparametric Prostate Magnetic Resonance Imaging on Ejaculation","Inclusion Criteria:\n\n* \\- Male aged 18 to 55 years\n* In a stable, heterosexual, monogamous relationship with the same female partner for at least 6 months\n* Normal erectile function defined as IIEF-15 erectile function domain score ≥26\n* Scheduled for clinically indicated multiparametric prostate MRI due to elevated PSA or hematospermia\n* Not using any medication that may affect sexual function or psychological status (e.g., SSRIs, PDE5 inhibitors)\n\nExclusion Criteria:\n\n* Any major psychiatric or somatic disorder\n* Hormonal disorders such as hypothyroidism or hyperthyroidism\n* Erectile dysfunction (IIEF-15 erectile function domain score \\\u003C26)\n* Age below 18 or above 55 years","MALE","55 Years",{"count":213,"type":23},150,"The goal of this observational study is to learn whether the size and shape of the prostatic urethra and seminal vesicles - measured on multiparametric prostate MRI (mpMRI) - are related to premature ejaculation (PE) severity in men aged 18-55.\n\nThe main questions it aims to answer are:\n\n* Do men with premature ejaculation have different prostatic urethral length and angulation compared to men without PE?\n* Do men with premature ejaculation have different seminal vesicle dimensions compared to men without PE?\n* Do prostatic urethra and seminal vesicle measurements on mpMRI correlate with PE severity scores (PEDT) and ejaculation latency time (IELT)?\n\nResearchers will compare men with premature ejaculation to healthy men without ejaculatory complaints to see if specific anatomical features are associated with PE severity.\n\nParticipants will:\n\n* Undergo a multiparametric prostate MRI that is already scheduled as part of their routine medical care\n* Complete validated questionnaires about ejaculation and sexual function (PEDT, PEP, IELT, IIEF-15)\n* Provide a blood sample for routine hormone level measurements",[216,217],"Premature Ejaculation","Ejaculation",[219,220,221],"Prostatic Urethra","seminal vesicle","morphometry","2026-05-30",{"date":224,"type":40},"2026-06-03",{"date":226,"type":23},"2026-05-10",{"date":228,"type":23},"2026-08-10",{"name":46,"class":47},{"id":231,"slug":232,"hasResults":12,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":4,"eligibilityCriteria":236,"healthyVolunteers":12,"sex":84,"minAge":19,"maxAge":237,"enrollmentInfo":238,"targetDuration":4,"studyType":87,"phases":240,"briefSummary":241,"conditions":242,"keywords":244,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":250,"lastUpdatePostDateStruct":251,"startDateStruct":253,"completionDateStruct":255,"leadSponsor":257,"locationsCount":4},"100638683","sentinel-lymph-node-mapping-in-early-stage-epithelial-ovarian-cancer-surgery-100638683","NCT07593339","Sentinel Lymph Node Mapping in Early-Stage Epithelial Ovarian Cancer Surgery","Feasibility and Evaluation of Sentinel Lymph Node Mapping in Early-Stage Epithelial Ovarian Cancer Surgery: A Tertiary Center Prospective Cohort Study","Inclusion Criteria:\n\n* Female patients aged 18-90 years\n* Patients undergoing laparotomy for unilateral or bilateral adnexal mass\n* Intraoperative frozen section diagnosis of malignant epithelial ovarian tumor or at least borderline epithelial tumor\n* Patients with bilateral adnexal masses who have undergone preoperative gastrointestinal evaluation (endoscopy\u002Fcolonoscopy) with exclusion of gastrointestinal malignancies\n* Patients without radiological evidence of advanced-stage ovarian cancer on preoperative imaging (PET, MRI, or CT), including absence of pleural effusion, omental cake, peritoneal carcinomatosis, malignant ascites, liver or splenic parenchymal involvement, and mesenteric involvement\n* Patients who provide written informed consent\n\nExclusion Criteria:\n\n* Patients with prior lymphadenectomy\n* Patients with radiological or intraoperative evidence of advanced-stage ovarian cancer\n* Patients planned for neoadjuvant chemotherapy without primary surgery\n* Pregnant patients\n* Patients with known allergy to indocyanine green (ICG) or iodine\n* Patients with immunodeficiency disorders\n* Patients with a history of radiotherapy\n* Patients with a history of vascular surgery affecting lymphatic drainage\n* Patients with a history of vascular surgery affecting lymphatic drainage\n* Patients with a history of non-gynecological malignancy\n* Patients younger than 18 years or older than 90 years","90 Years",{"count":239,"type":23},30,[89],"This prospective study aims to evaluate the feasibility and diagnostic performance of sentinel lymph node (SLN) mapping using indocyanine green (ICG) in patients undergoing surgery for early-stage epithelial ovarian cancer. Ovarian cancer is the most lethal gynecologic malignancy, and although systematic pelvic and paraaortic lymphadenectomy is considered a standard component of surgical staging. Moreover, systematic lymphadenectomy is associated with increased operative time, perioperative morbidity, and long-term complications such as lymphedema, without clear evidence of therapeutic benefit.\n\nSLN mapping has been successfully implemented in other gynecologic malignancies and may provide a less invasive alternative for lymph node assessment. In this study, patients undergoing laparotomy for adnexal masses will receive intraoperative ICG injection into the infundibulopelvic ligament on the affected side and into the cervix (at the 3 and 9 o'clock positions) following intraoperative confirmation of malignant epithelial tumor by frozen section analysis. SLN detection rates, anatomical distribution, and feasibility will be assessed. In addition, intraoperative and postoperative outcomes and potential complications related to the procedure will be evaluated.\n\nThe results of this study are expected to contribute to the current evidence regarding the role of SLN mapping in early-stage epithelial ovarian cancer and may help reduce the need for systematic lymphadenectomy and its associated morbidity.",[243],"Epithelial Ovarian Cancer",[245,246,247,248,249],"Sentinel Lymph Node","Indocyanine Green","Ovarian Cancer","Surgical Staging","Sentinel Lymph Node Mapping","2026-05-12",{"date":252,"type":40},"2026-05-18",{"date":254,"type":23},"2026-06-01",{"date":256,"type":23},"2028-03-01",{"name":46,"class":47},{"id":259,"slug":260,"hasResults":12,"nctId":261,"briefTitle":262,"officialTitle":263,"acronym":4,"eligibilityCriteria":264,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":265,"targetDuration":4,"studyType":87,"phases":267,"briefSummary":268,"conditions":269,"keywords":276,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":280,"lastUpdatePostDateStruct":281,"startDateStruct":283,"completionDateStruct":285,"leadSponsor":286,"locationsCount":76},"100579224","comparison-of-pain-relief-methods-for-hip-surgery-a-study-on-two-different-nerve-block-techniques-100579224","NCT06821516","Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques","Comparison of Analgesic Effectiveness Between Pericapsular Nerve Group (PENG) Block and Lumbar Erector Spinae Plane Block in Patients Undergoing Total Hip Arthroplasty With Spinal Anesthesia: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Voluntary willingness to participate in the study.\n* Patients who will undergo Total Hip Arthroplasty surgery.\n* Patients aged over 18 years.\n* ASA score I-II-III.\n* Patients who are fully oriented and can cooperate.\n\nExclusion Criteria:\n\n* ASA score IV-V.\n* Patients who refuse to participate in the study.\n* Patients under 18 years of age.\n* Presence of active infection in the area to be operated on.\n* Chronic pain and continuous analgesic use.\n* Patients with coagulation disorders.\n* Patients who cannot cooperate with postoperative pain follow-up.\n* Patients with allergies to local anesthetic agents.\n* Presence of neuropathy or myopathy in the operated extremity.",{"count":266,"type":23},52,[89],"This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over the age of 18 undergoing total hip arthroplasty under spinal anesthesia. The main question it aims to answer is:\n\nTo demonstrate whether PENG block or L-ESP block is more effective in postoperative analgesia in patients undergoing total hip arthroplasty surgery based on pain scores, opioid consumption, and patient satisfaction.\n\nTotal hip arthroplasties cause severe pain with movement in the postoperative period. After surgery, the movements of the participants are severely restricted, which increases the possibility of complications. In this study, the participants' pain status, VAS score, opioid consumption through patient-controlled analgesia, and patient satisfaction will be measured with a questionnaire for 24 hours at predetermined time points and then compared. Both types of blocks have pain-relieving effects. This study will only investigate which one is more effective in reducing pain, and there will be no deficiency in relieving the pain of the participants.",[270,271,272,273,274,275,160],"Opioid Consumption, Postoperative","Pain, Postoperative","Nerve Block","PENG Block","Lumbar Erector Spinae Plane Block","Hip Replacement, Total",[277,274,278,279],"Pericapsular Nerve Group (PENG) Block","Total Hip Arthroplasty","Postoperative analgesia","2026-05-01",{"date":282,"type":40},"2026-05-07",{"date":284,"type":40},"2025-01-21",{"date":254,"type":23},{"name":46,"class":47},{"id":288,"slug":289,"hasResults":12,"nctId":290,"briefTitle":291,"officialTitle":292,"acronym":4,"eligibilityCriteria":293,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":294,"enrollmentInfo":295,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":297,"conditions":298,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":301,"lastUpdatePostDateStruct":302,"startDateStruct":304,"completionDateStruct":305,"leadSponsor":307,"locationsCount":4},"100634371","ori-monitoring-in-low-and-normal-flow-anesthesia-applications-100634371","NCT07538817","ORI MONITORING IN LOW AND NORMAL FLOW ANESTHESIA APPLICATIONS","EVALUATION OF OXYGEN RESERVE INDEX IN LOW AND NORMAL FLOW ANESTHESIA APPLICATIONS IN LAPAROSCOPIC NEPHRECTOMY CASES IN LATERAL DECUBIT POSITION","Inclusion Criteria:\n\n* Ages 18-75\n* ASA I,II\n* elective surgery laparoscopic nephrectomy\n\nExclusion Criteria:\n\n* ASA III,IV,V\n* BMI \\> 35\n* Those with serious respiratory disease\n* Medications that cause peripheral circulation disorders\n* Patients who started with laparoscopic surgery and then underwent open surgery","75 Years",{"count":296,"type":23},48,"Oxygen administration is essential in the perioperative period to prevent hypoxia; however, excessive oxygen may cause hyperoxia and related complications. While pulse oximetry is effective in detecting hypoxemia, it is insufficient for identifying hyperoxia when SpO₂ exceeds 97%, often necessitating invasive arterial blood gas analysis. The Oxygen Reserve Index (ORI) is a noninvasive, real-time monitoring parameter reflecting moderate hyperoxic ranges (PaO₂ 100-200 mmHg) and provides early warning of oxygenation changes before SpO₂ alterations occur. Combined use of ORI and pulse oximetry may enable optimal oxygen titration and prevention of both hypoxemia and hyperoxemia.\n\nLaparoscopic nephrectomy is widely performed due to its clinical advantages. In our practice, low and normal fresh gas flow anesthesia are commonly used. Low-flow anesthesia offers benefits such as preservation of heat and humidity, reduced cost, and improved airway physiology. This study aims to determine optimal oxygenation levels during laparoscopic nephrectomy under low and normal fresh gas flow conditions using ORI monitoring.",[299,300],"HYPEROXY","OXYGEN RESERVE INDEX","2026-04-13",{"date":303,"type":40},"2026-04-20",{"date":303,"type":23},{"date":306,"type":23},"2026-08-20",{"name":46,"class":47},{"id":309,"slug":310,"hasResults":12,"nctId":311,"briefTitle":312,"officialTitle":313,"acronym":314,"eligibilityCriteria":315,"healthyVolunteers":12,"sex":84,"minAge":316,"maxAge":317,"enrollmentInfo":318,"targetDuration":4,"studyType":87,"phases":320,"briefSummary":321,"conditions":322,"keywords":326,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":339,"lastUpdatePostDateStruct":340,"startDateStruct":342,"completionDateStruct":344,"leadSponsor":345,"locationsCount":76},"100618092","effect-of-skin-closure-techniques-on-body-image-in-women-undergoing-gynecologic-surgery-100618092","NCT07327125","Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery","Effect of Skin Closure Techniques on Body Image and Mood in Gynecologic Oncology Patients","BISGO","Inclusion Criteria:\n\n* Female participants aged 18 years or older.\n* Patients scheduled for elective open gynecologic surgery for suspected or confirmed gynecologic malignancy.\n* Surgery planned to be performed via a vertical midline laparotomy incision.\n* Literate patients capable of reading, understanding, and completing the Body Image Scale (BIS) and Hospital Anxiety and Depression Scale (HADS).\n* Patients who provide written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* History of prior radiotherapy to the abdominal or pelvic region.\n* Patients currently receiving chronic immunosuppressive therapy.\n* Body Mass Index (BMI) less than 18 kg\u002Fm\\^2 or greater than 40 kg\u002Fm\\^2.\n* Presence of cognitive impairment, dementia, or Alzheimer's disease.\n* Major psychiatric disorders that prevent the patient from understanding or completing the questionnaires.\n* Patients undergoing emergency surgery.","17 Years","60 Years",{"count":319,"type":23},140,[89],"This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.\n\nPatients undergoing elective surgery with a midline abdominal incision will be randomly assigned to one of two groups: 1. Interrupted Closure Group: The surgical incision is closed using either metal clips (staples) or separate mattress sutures (individual stitches). 2. Subcuticular Sutures Group: The surgical incision is closed using continuous stitches placed under the skin surface (aesthetic stitching).\n\nThe main goal of the study is to determine whether the method of wound closure affects a patient's perception of their body image, cosmetic satisfaction, and levels of anxiety or depression.\n\nAdditionally, the study aims to prove that the subcuticular suture technique is safe and does not increase the risk of wound complications (such as infection or wound separation) compared to the other method.\n\nParticipants will be asked to complete questionnaires before surgery, and again at 1, 3 and 6 months after surgery to track changes in their feelings and satisfaction with the scar.",[323,324,325],"Gynecologic Cancers","Surgical Wound Closure Techniques","Body Image",[327,328,329,330,325,331,332,333,95,334,335,336,337,338],"surgical staples","Subcuticular Sutures","Gynecologic Oncology","Skin Closure Techniques","Surgical Wound","Laparotomy","Cicatrix","Depression","Midline Incision","Wound Dehiscence","Wound Complications","Surgical Site Infection","2026-04-12",{"date":341,"type":40},"2026-04-14",{"date":343,"type":40},"2026-01-01",{"date":256,"type":23},{"name":46,"class":47},{"id":347,"slug":348,"hasResults":12,"nctId":349,"briefTitle":350,"officialTitle":351,"acronym":4,"eligibilityCriteria":352,"healthyVolunteers":12,"sex":18,"minAge":353,"maxAge":354,"enrollmentInfo":355,"targetDuration":4,"studyType":87,"phases":357,"briefSummary":358,"conditions":359,"keywords":361,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":366,"lastUpdatePostDateStruct":367,"startDateStruct":369,"completionDateStruct":370,"leadSponsor":372,"locationsCount":76},"100627823","white-noise-and-crying-duration-after-invasive-procedures-in-infants-100627823","NCT07453641","White Noise and Crying Duration After Invasive Procedures in Infants","The Effect of White Noise on Crying Duration After Invasive Procedures in Infants Aged 1-3 Months","Inclusion Criteria:\n\n* Infants aged 1-3 months\n* Born at term (≥37 weeks gestational age)\n* Admitted to the general pediatric ward\n* Scheduled for routine invasive procedures such as venipuncture or intravenous line placement\n\nExclusion Criteria:\n\n* Infants with congenital anomalies\n* Infants with hearing impairments\n* Infants with a history of analgesic or pain-relieving medication use prior to the invasive procedure\n* Infants requiring intensive care unit (ICU) monitoring","1 Month","3 Months",{"count":356,"type":23},37,[89],"The aim of this study is to evaluate the effect of white noise applied during invasive procedures (blood sampling or intravenous access) on pain and physical parameters in infants aged 1-3 months.",[360],"White Noise",[362,360,363,364,365],"Infant","Invasive Procedures","Cry","Pain","2026-03-15",{"date":368,"type":40},"2026-03-17",{"date":343,"type":40},{"date":371,"type":23},"2026-04-15",{"name":46,"class":47},{"id":374,"slug":375,"hasResults":12,"nctId":376,"briefTitle":377,"officialTitle":378,"acronym":4,"eligibilityCriteria":379,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":380,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":382,"conditions":383,"keywords":387,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":391,"lastUpdatePostDateStruct":392,"startDateStruct":394,"completionDateStruct":396,"leadSponsor":398,"locationsCount":76},"100616493","ultrasound-in-predicting-difficult-intubation-in-acromegaly-patients-100616493","NCT07306325","Ultrasound in Predicting Difficult Intubation in Acromegaly Patients","Effectiveness of Ultrasonography in Evaluating the Airway and Predicting Difficult Intubation in Patients Diagnosed With Acromegaly","Inclusion Criteria:\n\n* • Patients diagnosed with acromegaly who are planned for endoscopic pituitary surgery\n\n  * Volunteer participants\n  * American Society of Anesthesiology - ASA 1, 2 and 3 patient groups\n  * Patients with BMI\\\u003C40\n\nExclusion Criteria:\n\n* ASA 4 patient group\n\n  * History of previous neck surgery\n  * Patients with a history of tracheostomy\n  * Patients with a history of radiotherapy to the neck area\n  * Patients with limited neck extension (rheumatological - traumatic reasons)\n  * Patients with masses and lesions in the mouth and airway that may make intubation difficult.",{"count":381,"type":23},34,"This is a prospective observational study.The purpose of this study is to predict difficult intubation with ultrasonographic evaluation combined with preoperative physical examination in patients diagnosed with acromegaly and planned for pituitary surgery.",[384,385,386],"Acromegaly Due to Pituitary Adenoma","Difficult Intubation","Airway Ultrasonography",[388,389,390],"difficult intubation","acromegaly","airway ultrasonography","2025-12-13",{"date":393,"type":40},"2025-12-29",{"date":395,"type":23},"2025-12-25",{"date":397,"type":23},"2026-03-20",{"name":46,"class":47},{"id":400,"slug":401,"hasResults":12,"nctId":402,"briefTitle":403,"officialTitle":404,"acronym":4,"eligibilityCriteria":405,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":406,"targetDuration":4,"studyType":87,"phases":408,"briefSummary":409,"conditions":410,"keywords":412,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":418,"lastUpdatePostDateStruct":419,"startDateStruct":421,"completionDateStruct":423,"leadSponsor":424,"locationsCount":76},"100606020","predictors-of-gon-blockade-success-in-migraine-100606020","NCT07170111","Predictors of GON Blockade Success in Migraine","Predictive Factors for the Success of Greater Occipital Nerve Block in Migraine: A Multicenter Prospective Study","Inclusion Criteria:\n\n* Diagnosis of migraine for at least 6 months, according to ICHD-3 criteria\n* Age between 18 and 65 years\n* Inadequate response to preventive therapy used regularly for at least 3 months\n* Planned treatment with greater occipital nerve block (GONB) and provision of signed informed consent\n* Receiving GONB treatment for the first time\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Presence of malignancy\n* Coagulopathy or anticoagulant therapy\n* Local infection, open wound, or history of surgery at the injection site preventing the procedure\n* History of severe neurological or psychiatric disorders\n* Receipt of interventional treatment (e.g., Botox, acupuncture, neural therapy, nerve blocks) within the last 3 months\n* Use of steroids or immunosuppressive therapy\n* Start of a new preventive therapy within the last 3 months\n* Inability to comply with keeping a headache diary\n* Known hypersensitivity or allergy to bupivacaine",{"count":407,"type":23},460,[89],"This multicenter, prospective cohort study aims to identify clinical and demographic predictors that influence the success of greater occipital nerve (GON) block in patients with migraine.\n\nPatients will be evaluated at baseline, on each injection day, and at one- and three-month follow-ups. Study parameters include demographics, migraine type and duration, comorbidities, headache characteristics, treatment history, and validated outcome measures such as the Numeric Rating Scale (NRS), Headache Impact Test-6 (HIT-6), and Global Rating of Change (GRoC).\n\nThe goal is to establish predictive factors of treatment success in order to optimize patient selection and contribute robust multicenter evidence to individualized migraine management",[411],"Migraine",[413,414,415,416,417],"migraine","GON block","greater occipital nerve","greater occipital nerve block","predictive factors","2025-09-05",{"date":420,"type":40},"2025-09-12",{"date":422,"type":23},"2025-09-15",{"date":44,"type":23},{"name":46,"class":47},{"id":426,"slug":427,"hasResults":12,"nctId":428,"briefTitle":429,"officialTitle":430,"acronym":4,"eligibilityCriteria":431,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":432,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":434,"conditions":435,"keywords":438,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":444,"lastUpdatePostDateStruct":445,"startDateStruct":447,"completionDateStruct":448,"leadSponsor":450,"locationsCount":4},"100596643","turkish-version-of-the-headache-screening-questionnaire-100596643","NCT07048132","Turkish Version of the Headache Screening Questionnaire","Validity and Reliability of the Turkish Version of the Headache Screening Questionnaire","Inclusion Criteria:\n\n* Individuals aged 18 and over who present with headache complaints (migraine or tension-type) and voluntarily agree to participate\n\nExclusion Criteria:\n\n* Individuals with severe psychiatric disorders, illiteracy in Turkish, or significant cognitive impairment preventing comprehension of the scale",{"count":433,"type":23},200,"This multi-center, nationwide study aims to evaluate the validity and reliability of the Turkish version of the Headache Screening Questionnaire (HSQ-TR). The 10-item questionnaire is designed to screen for migraine and tension-type headache in individuals with headache complaints.\n\nParticipants presenting with headache will be enrolled. Each participant will first complete the HSQ-TR and then be examined by a neurologist who will provide a diagnosis according to the ICHD-3 beta criteria. The questionnaire results will be compared with the neurologist's diagnoses to assess criterion validity, including sensitivity, specificity, and agreement.",[411,436,437],"Tension Type Headache","Headache",[413,439,440,441,442,443],"tension type headache","headache","headache screening questionare","validation","reliability","2025-07-11",{"date":446,"type":40},"2025-07-15",{"date":446,"type":23},{"date":449,"type":23},"2025-12-15",{"name":46,"class":47},{"id":452,"slug":453,"hasResults":12,"nctId":454,"briefTitle":455,"officialTitle":456,"acronym":4,"eligibilityCriteria":457,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":458,"enrollmentInfo":459,"targetDuration":4,"studyType":87,"phases":460,"briefSummary":461,"conditions":462,"keywords":466,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":471,"startDateStruct":473,"completionDateStruct":475,"leadSponsor":477,"locationsCount":76},"100586013","comparison-of-pain-relief-after-arthroscopic-knee-surgery-adductor-canal-block-and-genicular-nerve-block-100586013","NCT06909851","Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block","Comparison of the Effectiveness of Adductor Canal Block and Genicular Nerve Block on Postoperative Pain and Analgesic Use in Arthroscopic Knee Surgeries","Inclusion Criteria:\n\n* Voluntary willingness to participate in the study.\n* Patients undergoing arthroscopic knee surgery (meniscus, ACL, arthroscopic intervention etc).\n* ASA I-II-III classification.\n* Aged between 18-72 years.\n* No contraindications for regional anesthesia, and deemed suitable for regional anesthesia by the anesthesiologist.\n* Undergoing surgery under spinal anesthesia.\n* Fully oriented and able to cooperate.\n\nExclusion Criteria:\n\n* Undergoing surgery under general anesthesia.\n* Chronic analgesic use.\n* Presence of an active infection at the procedure site.\n* Outside the appropriate age range.\n* Inability to comply with postoperative pain\u002FNRS follow-ups.\n* ASA IV-V classification.\n* Non-voluntary patients.\n* Pregnancy.","72 Years",{"count":86,"type":23},[89],"This prospective randomized study aims to compare the analgesic efficacy of Adductor Canal Block (ACB) and Genicular Nerve Block (GNB) groups to relieve postoperative pain in participants between ages of 18-72 undergoing arthroscopic knee surgery under spinal anesthesia. The main question it aims to answer is:\n\nTo demonstrate whether Adductor Canal Block or Genicular Nerve Block is more effective in postoperative analgesia in patients undergoing arthroscopic knee surgery based on pain scores, opioid consumption and patient satisfaction.\n\nArthroscopic knee surgeries cause severe pain especially with movement in the post-operative period. After surgery, the movements of the participants are severely restricted because of pain, which increases the possibility of complications and postpones post-operative knee exercises. In this study, the participants' pain status, VAS score, opioid consumption and patient satisfaction will be measured with a simple scoring system for 24 hours at predetermined time points and then compared. Both types of blocks have pain-relieving effects. This study will only investigate which one is more effective in reducing pain, and there will be no deficiency in relieving the pain of the participants.",[463,464,465],"Opioid Use","Pain Postoperative","Arthroscopic Knee Surgeries",[467,468,469,160],"Genicular Nerve Block","Arthroscopic Knee Surgery","Adductor Canal Block","2025-03-27",{"date":472,"type":40},"2025-04-04",{"date":474,"type":40},"2025-03-10",{"date":476,"type":23},"2025-09-30",{"name":46,"class":47},{"id":479,"slug":480,"hasResults":12,"nctId":481,"briefTitle":482,"officialTitle":483,"acronym":484,"eligibilityCriteria":485,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":486,"targetDuration":4,"studyType":87,"phases":488,"briefSummary":489,"conditions":490,"keywords":494,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":500,"lastUpdatePostDateStruct":501,"startDateStruct":503,"completionDateStruct":505,"leadSponsor":507,"locationsCount":76},"100543585","closed-loop-synchronization-versus-conventional-synchronization-in-spontaneously-breathing-adult-nonivasive-ventilationpatients-100543585","NCT06357780","Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive ventilationPatients","Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive Ventilation Patients (CHEST-SPAN) - a Randomized Cross-over Trial","CHESTSPAN","Inclusion Criteria:\n\n* Adult patients older than 18 years of age\n* Hospitalized at the ICU or emergency department with the intention of treatment with Noninvasive ventilation at least for the upcoming 2 hours with spontaneous breathing activity\n* Written informed consent signed and dated by the patient or one relative in case that the patient is unable to consent, after full explanation of the study by the investigator and prior to study participation\n\nExclusion Criteria:\n\n* Formalized ethical decision to withhold or withdraw life support\n* Patient included in another interventional research study under consent\n* Patient already enrolled in the present study in a previous episode of respiratory failure\n* Pregnant woman\n* Patients deemed at high risk for the need of transportation from an intensive care unit or emergency department to another ward, diagnostic unit or any other hospital\n* Hemodynamic instability defined as a need of continuous infusion of epinephrine or norepinephrine \\> 1 mg\u002Fh\n* Not being able to obtain reference waveforms due to technical or medical problems\n* Vulnerable population\n* Increase or decrease of ventilatory support either in pressures, fraction of inspired oxygen or mode of ventilation during study period",{"count":487,"type":23},38,[89],"The study is a multicentric prospective randomised cross-over study. It evaluates the compatibility of patients with the device without altering the routine treatment applied. During this evaluation, either the clinician-adjusted values on the device or the standard pre-set values are used to obtain hourly and 30-minute PVA (Patient Ventilator Asynchrony) recordings. These recordings will be analysed offline to identify the settings used and to compare the hourly and 30-minute PVA (Patient Ventilator Asynchrony) values when synchronisation is automatically set. The relationships and differences between these values will be analysed. For this purpose, the IntelliSync+ option, already available on the device, will be used. This software continuously analyses waveform signals at least a hundred times per second. This allows for the immediate detection of patient efforts and the initiation of inspiration and expiration in real time, thereby replacing traditional trigger settings for inspiration and expiration. If the patient is already synchronised with this option, it will then be possible to switch to traditional synchronisation settings for comparison. Statistical analyses will be conducted using SPSS 24.0, JASP (Just Another Statistical Programme), Jamovi ( fork of JASP), or R software. Initially, all numerical and categorical data will be evaluated using descriptive statistical methods. The distributions of numerical variables will be examined using visual (histograms and probability plots) and analytical methods (Kolmogorov-Smirnov\u002FShapiro-Wilk tests). Mean\u002FSD (standard deviation) or median\u002Finterquartile range (IQR) will be used as measures of distribution. For comparing numerical data that follows a normal distribution, the Student-t test will be used, and for non-normally distributed data, the Mann-Whitney U or Wilcoxon signed-rank tests will be employed. PVA (Patient Ventilator Asynchrony) values will be statistically compared. For the analysis of categorical data, the Chi-Square test will be applied. Bayesian analysis may also be used as necessary during the writing of the study. The results obtained will be interpreted and reported by the researchers. Results with a \"p\" value below 0.05 will be considered statistically significant.",[491,492,493],"Acute Respiratory Failure","Acute Respiratory Distress Syndrome","Chronic Respiratory Failure",[495,496,497,498,499],"Acute respiratory failure (ARF)","noninvasive ventilation","Closed-loop","synchronization","patient ventilator asynchrony","2025-03-21",{"date":502,"type":40},"2025-03-26",{"date":504,"type":40},"2024-04-08",{"date":506,"type":23},"2025-12-31",{"name":46,"class":47},{"id":509,"slug":510,"hasResults":12,"nctId":511,"briefTitle":512,"officialTitle":512,"acronym":4,"eligibilityCriteria":513,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":514,"targetDuration":4,"studyType":87,"phases":515,"briefSummary":516,"conditions":517,"keywords":520,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":530,"locationsCount":76},"100584225","ultrasound-guided-ganglion-impar-block-100584225","NCT06886568","Ultrasound Guided Ganglion Impar Block","Inclusion Criteria:\n\n* Age between 18-65 years.\n* Coccydynia persisting for at least three months.\n* Being scheduled for a ganglion impar block in the pain medicine outpatient clinic.\n* Having inadequate response to medical and conservative treatments.\n* Aggreeing to undergo the interventional procedure and participate in the study.\n\nExclusion Criteria:\n\n* Local infection at the injection site.\n* Bleeding disorders or diseases and drugs that may cause bleeding diatesis (e.g. renal failure, liver failure, anticoagulant treatments)\n* History of allergic reaction to the medications to be used.\n* Pregnancy",{"count":239,"type":23},[89],"The aim of this study is to evaluate feasibility, reliability and short term effectiveness of ganglion impar block with ultrasound in patients with chronic coccygodinia.",[518,519],"Coccydynia","Chronic Pain",[518,521,522,523],"pain","ultrasound guided injection","ganglion impar","2025-03-19",{"date":526,"type":40},"2025-03-20",{"date":528,"type":23},"2025-04-01",{"date":446,"type":23},{"name":46,"class":47},{"id":532,"slug":533,"hasResults":12,"nctId":534,"briefTitle":535,"officialTitle":536,"acronym":4,"eligibilityCriteria":537,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":538,"targetDuration":4,"studyType":87,"phases":540,"briefSummary":541,"conditions":542,"keywords":544,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":547,"startDateStruct":549,"completionDateStruct":551,"leadSponsor":553,"locationsCount":76},"100582100","comparison-of-impar-ganglion-block-and-sacral-erector-spinae-plane-block-in-patients-with-coccygodynia-100582100","NCT06858917","Comparison of Impar Ganglion Block and Sacral Erector Spinae Plane Block in Patients with Coccygodynia","Comparison of Impar Ganglion Block and Sacral Erector Spinae Plane Block for Chronic Coccygodynia: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Those who have had chronic coccygodynia for at least 3 months\n* Being between the ages of 18-65\n* Patients who do not respond to conservative treatments (analgesics, physical therapy modalities etc.) and are scheduled for interventional pain procedures\n\nExclusion Criteria:\n\n* Patients who have undergone surgery to the coccyx region\n* Having undergone an interventional pain procedure in the lumbar, sacral and coccyx regions within the last year\n* Patients with systemic infection, local infection at the application site, and coagulopathy\n* Pregnant and breastfeeding patients\n* Having endocrine or rheumatological disease that may affect the musculoskeletal system in the relevant region and lead to diagnostic complexity (such as spondyloarthropathy)\n* Patients with musculoskeletal system pathology that may contribute to symptoms in the relevant region and affect the evaluation of treatment results (such as lumbar disc herniation, sacroiliitis, spinal stenosis)\n* Those with lumbar, sacral or coccygeal vertebra fractures\n* Those with a history of allergic reactions to the contents of the injectate to be administered during an interventional pain procedure (especially contrast agent and local anesthetic)\n* Those with mental disorders that may affect the evaluation during the follow-up periods during the study",{"count":539,"type":23},130,[89],"Coccygodynia is a condition that causes pain in the tailbone (coccyx) area. While it can develop after trauma, such as a fall or fracture, in some cases, no clear cause is identified. Patients who do not experience relief from standard treatments like pain medications, physical therapy, and posture adjustments may be referred to specialized pain management clinics for further treatment options.\n\nSeveral interventional procedures can help manage coccygodynia. These include impar ganglion block, radiofrequency ablation, caudal epidural steroid injections, sacral erector spinae plane (ESP) block, and coccygeal nerve blocks. These procedures are commonly performed in pain treatment centers and aim to reduce discomfort by targeting specific nerves responsible for transmitting pain signals.\n\nImpar ganglion block is one of the most frequently used treatments for coccygodynia. It involves injecting a local anesthetic, with or without steroids, into a small nerve cluster in front of the sacrococcygeal joint. This procedure is performed under ultrasound and\u002For fluoroscopic (X-ray) guidance in a sterile operating room setting to ensure accuracy and safety. While the goal is to relieve pain, potential risks include temporary worsening of pain, bleeding, infection, or, in rare cases, rectal injury.\n\nAnother interventional option is the sacral erector spinae plane (ESP) block, a technique that delivers local anesthetic under the erector spinae muscles in the sacrum. This procedure, also performed under ultrasound guidance in a sterile environment, is used to block pain signals from the coccyx and surrounding areas. Like the impar ganglion block, it can be effective for pain relief, but possible side effects include temporary pain increase, bleeding, and infection at the injection site.\n\nBoth procedures are minimally invasive.",[543,518],"Coccygodynia",[543,518,545,546],"impar block","sacral erector spinae plane block",{"date":548,"type":40},"2025-03-24",{"date":550,"type":40},"2025-03-15",{"date":552,"type":23},"2025-10-15",{"name":46,"class":47},{"id":555,"slug":556,"hasResults":12,"nctId":557,"briefTitle":558,"officialTitle":559,"acronym":4,"eligibilityCriteria":560,"healthyVolunteers":12,"sex":18,"minAge":55,"maxAge":4,"enrollmentInfo":561,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":562,"conditions":563,"keywords":566,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":568,"lastUpdatePostDateStruct":569,"startDateStruct":570,"completionDateStruct":571,"leadSponsor":573,"locationsCount":76},"100583527","turkish-validation-of-the-geriatric-pain-measure---short-form-100583527","NCT06877481","Turkish Validation of the Geriatric Pain Measure - Short Form","Turkish Adaptation, Validation, and Reliability Assessment of the Geriatric Pain Measure - Short Form","Inclusion Criteria:\n\n* Geriatric patients with chronic pain\n* Patients who agreed to participate in the study\n\nExclusion Criteria:\n\n* Demantia\n* Mental of physical disorders that effect patients answering the scales\n* Diagnosis of malignancy",{"count":213,"type":23},"This study aims to adapt, validate, and assess the reliability of the Geriatric Pain Measure - Short Form in Turkish. A total of 150 patients aged 65 years and older will complete the scale under the supervision of pain management and gerontology specialists. Reliability and validity will be evaluated using statistical analyses, including internal consistency, test-retest reliability, and correlation with validated pain and sleep scales. Ethical approval has been obtained, and all participants will provide informed consent.",[564,565,519],"Geriatric Assessment","Pain Measurement",[564,565,519,567],"Geriatric Pain Measurement Short Form","2025-03-18",{"date":526,"type":40},{"date":550,"type":40},{"date":572,"type":23},"2025-06-15",{"name":46,"class":47},{"id":575,"slug":576,"hasResults":12,"nctId":577,"briefTitle":578,"officialTitle":579,"acronym":4,"eligibilityCriteria":580,"healthyVolunteers":12,"sex":18,"minAge":581,"maxAge":149,"enrollmentInfo":582,"targetDuration":4,"studyType":87,"phases":583,"briefSummary":584,"conditions":585,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":588,"lastUpdatePostDateStruct":589,"startDateStruct":591,"completionDateStruct":593,"leadSponsor":594,"locationsCount":76},"100537466","masseter-muscle-thickness-in-gasser-ganglion-radiofrequency-treatment-100537466","NCT06278194","Masseter Muscle Thickness in Gasser Ganglion Radiofrequency Treatment","Change of the Masseter Muscle Thickness Measured by Ultrasonography After Gasser Ganglion Radiofrequency Thermocoagulation Treatment","Inclusion Criteria:\n\n* Pain refractory to medical therapy for at least 3 months\n* Planning radiofrequency thermocoagulation of gasserian ganglion\n* Accept ultrasound measurements to be performed\n\nExclusion Criteria:\n\n* Refused to participate in the study\n* Not attending follow-ups regularly\n* Coagulation disorder\n* Pregnancy\n* Localized or systemic infection","40 Years",{"count":239,"type":23},[89],"Trigeminal neuralgia is common painful disorder in pain medicine clinics. Gasserian ganglion radiofrequency thermocoagulation is one of the treatment option in patients with trigeminal neuralgia in refractory cases. The most commonly involved branch in trigeminal neuralgia is the mandibular branch. Masseter muscle is innervated by mandibulary nerve branch of the trigeminal nerve.\n\nThe radiofrequency thermocoagulation therapy is used to ablate the affected trigeminal nerve branch and some of patients complain of subjective masseter weakness after this procedure.\n\nIn theoretical basis, muscles innervated by target nerve are affected from ablation procedure. In this study the primary aim is to evaluate the change of the masseter muscle thickness in patients treated by gasserian ganglion radiofrequency thermocoagulation. The results may also show possible functional effect of the procedure related with masseter muscle.",[586,587],"Trigeminal Neuralgia","Gasserian Ganglion; Lesion","2025-03-03",{"date":590,"type":40},"2025-03-05",{"date":592,"type":40},"2024-03-15",{"date":552,"type":23},{"name":46,"class":47},{"id":596,"slug":597,"hasResults":12,"nctId":598,"briefTitle":599,"officialTitle":600,"acronym":601,"eligibilityCriteria":602,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":603,"targetDuration":4,"studyType":87,"phases":605,"briefSummary":606,"conditions":607,"keywords":612,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":614,"lastUpdatePostDateStruct":615,"startDateStruct":617,"completionDateStruct":619,"leadSponsor":620,"locationsCount":621},"100544876","closed-loop-o2-use-during-high-flow-oxygen-treatment-of-critical-care-adult-patients-cloudhfot-100544876","NCT06374589","Closed-Loop O2 Use During High Flow Oxygen Treatment of Critical Care Adult Patients (CLOUDHFOT)","Closed-Loop O2 Use During High Flow Oxygen Treatment of Critical Care Adult Patients (CLOUDHFOT)- a Randomized Cross-over Study","CLOUDHFOT","Inclusion Criteria:\n\n* Patient admitted to the ER\n* Requiring NHFO\n* Requiring FiO2 ≥ 30% to keep SpO2 in the target ranges defined by the clinician\n* Aged over 18 years\n* Written informed consent signed and dated by the patient or one relative in case that the patient is unable to consent, after full explanation of the study by the investigator and prior to study participation\n* In case that the consent is given by the relative, patient consent will be requested as soon as the patient will be able to provide informed written consent\n\nExclusion Criteria:\n\nPatients who fulfil any of the following exclusion criteria are not eligible for study participation:\n\n* Patient with indication for immediate CPAP, NIV, or invasive mechanical ventilation\n* Hemodynamic instability defined as a need of continuous infusion of epinephrine or norepinephrine \\> 1 mg\u002Fh\n* Low quality on the SpO2 measurement using finger and ear sensor (quality index below 60% on the Massimo SpO2 sensor, which is displayed by a red or orange color bar)\n* Severe acidosis (pH ≤ 7.30)\n* Pregnant woman\n* Patients deemed at high risk for need of mechanical ventilation within the next 12 hours\n* Chronic or acute dyshemoglobinemia: methemoglobin, CO poisoning, sickle cell disease\n* Tracheotomized patient\n* Formalized ethical decision to withhold or withdraw life support\n* Patient under guardianship\n* Patient deprived of liberties\n* Patient included in another interventional research study under consent\n* Patient already enrolled in the present study in a previous episode of acute respiratory failure\n\nPost enrollment exclusion criteria\n\n* Apparition of a persistent low quality SpO2 signal\n* Need for an emergent intubation\n* Discharge from ER",{"count":604,"type":23},50,[89],"High flow nasal oxygen therapy (HFNO) is an established modality in the supportive treatment of patients suffering from acute hypoxemic respiratory failure. The high humidified gas flow supports patient's work of breathing, reduces dead space ventilation, and improves functional residual capacity while using an unobtrusive patient's face interface \\[Mauri et al, 2017; Möller et al, 2017\\].\n\nAs hyperoxia is considered not desirable \\[Barbateskovic et al, 2019\\] during any oxygen therapy, the inspired O2 concentration is usually adapted to a pre-set SpO2 target-range of 92-96% in patients without hypercapnia risk, and of 88-92% if a risk of hypercapnia is present \\[O'Driscoll et al, 2017; Beasley et al, 2015\\]. In most institutions, the standard of care is to manually adapt the FiO2, although patients frequently have a SpO2 value outside the target range.\n\nA new closed loop oxygen controller designed for HFNO was recently developed (Hamilton Medical, Bonaduz, Switzerland). The clinician sets SpO2 targets, and the software option adjusts FiO2 to keep SpO2 within the target ranges. The software option offers some alarms on low and high SpO2 and high FiO2. Given the capability, on the one hand, to quickly increase FiO2 in patients developing sudden and profound hypoxia, and, on the other hand, of automatically preventing hyperoxia in patients improving their oxygenation, such a system could be particularly useful in patients treated with HFNO.\n\nA short-term (4 hours vs 4 hours) crossover study indicated that this technique improves the time spent within SpO2 pre-defined target for ICU patients receiving high-flow nasal oxygen therapy \\[Roca et al, 2022\\]. Due to its simplicity, HFNO is increasingly used outside the ICU during transport and in the Emergency Room (ER). This environment poses specific challenges, as patients may deteriorate very quickly and depending on patient's flow, healthcare providers can easily be overwhelmed. We thus propose to evaluate closed loop controlled HFNO in ER patients.\n\nThe hypothesis of the study is that closed loop oxygen control increases the time spent within clinically targeted SpO2 ranges and decreases the time spent outside clinical target SpO2 ranges as compared to manual oxygen control in ER patients treated with HFNO.",[608,609,610,611],"Acute Hypoxemic Respiratory Failure","Acute Hypercapnic Respiratory Failure","Respiratory Depression","Respiratory Failure",[495,613,497],"HFNC","2025-01-27",{"date":616,"type":40},"2025-01-28",{"date":618,"type":40},"2024-03-21",{"date":222,"type":23},{"name":46,"class":47},2,{"id":623,"slug":624,"hasResults":12,"nctId":625,"briefTitle":626,"officialTitle":626,"acronym":627,"eligibilityCriteria":628,"healthyVolunteers":12,"sex":84,"minAge":19,"maxAge":211,"enrollmentInfo":629,"targetDuration":4,"studyType":87,"phases":631,"briefSummary":632,"conditions":633,"keywords":638,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":643,"lastUpdatePostDateStruct":644,"startDateStruct":646,"completionDateStruct":648,"leadSponsor":650,"locationsCount":76},"100575765","evaluation-of-rectal-infiltration-depth-and-length-in-bowel-involvement-of-deep-infiltrative-endometriosis-die-using-intraoperative-transrectal-ultrasound-trus-100575765","NCT06776536","Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis (DIE) Using Intraoperative Transrectal Ultrasound (TRUS)","DIE IO TRUS","Inclusion Criteria:\n\n* The study will include a minimum of 15 female patients aged 18-55 with bowel involvement due to deep infiltrative endometriosis, requiring bowel resection.\n\nExclusion Criteria:\n\nPatients with bowel endometriosis who does not require bowel resection, patients who have other bowel diseases, such as rectal tumors, Crohn's disease, or ulcerative colitis, will be excluded.\n\n\\-",{"count":630,"type":23},15,[89],"we aim to evaluate the success of intraoperative transrectal ultrasound in measuring the depth and extent of bowel involvement in patients preoperatively diagnosed with intestinal endometriosis using transvaginal ultrasound and MRI, and who are planned for bowel resection",[634,635,636,637],"Deep Infiltrating Endometriosis (DIE)","Transrectal Ultrasound","Bowel Endometriosis","Bowel Resection",[639,640,641,642],"Deeply infiltrating endometriosis","bowel endometriosis","transrectal ultrasound","bowel resection","2025-01-10",{"date":645,"type":40},"2025-01-15",{"date":647,"type":23},"2025-01-07",{"date":649,"type":23},"2026-04-07",{"name":46,"class":47},{"id":652,"slug":653,"hasResults":12,"nctId":654,"briefTitle":655,"officialTitle":656,"acronym":4,"eligibilityCriteria":657,"healthyVolunteers":12,"sex":18,"minAge":658,"maxAge":659,"enrollmentInfo":660,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":662,"conditions":663,"keywords":665,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":647,"lastUpdatePostDateStruct":668,"startDateStruct":670,"completionDateStruct":672,"leadSponsor":673,"locationsCount":76},"100553869","can-optic-nerve-sheath-diameter-detect-norological-morbidities-for-patients-undergoing-carotis-endarterectomy-100553869","NCT06491693","Can Optic Nerve Sheath Diameter Detect Norological Morbidities for Patients Undergoing Carotis Endarterectomy","Can Ultrasonographic Screening of Optic Sheath Diameter Be an Early Detector of Norological Morbidities Related Carotis Endarterectomy","Inclusion Criteria:\n\n* Male and female patients between the ages of 50 and 80, who are planned for elective CEA under general anesthesia, who come in a spontaneously breathing, conscious and cooperative state.\n\nExclusion Criteria:\n\n* Patients who are under 50 years of age, over 80 years of age, have neurological findings caused by reasons other than carotid lesion, and are intubated.","50 Years","80 Years",{"count":661,"type":23},40,"The main purpose of this study is to investigate the contribution of changes in Optic Nerve Sheath Diameter (OSNC) measured at different periods during Carotid Endarterectomy (CEA) operations to the prediction of neurological problems detected in the postoperative period. The secondary aim of the study is to examine the relationship between optic nerve sheath diameter measurement and other routinely used perioperative follow-up parameters in terms of predicting neurological problems.",[664],"Optic Nerve Sheath Diameter Measurements for Carotis Endarterectomy",[666,667],"optic nerve sheath dimater","carotis endarterectomy",{"date":669,"type":40},"2025-01-08",{"date":671,"type":40},"2024-07-01",{"date":528,"type":23},{"name":46,"class":47},{"id":675,"slug":676,"hasResults":12,"nctId":677,"briefTitle":678,"officialTitle":679,"acronym":680,"eligibilityCriteria":681,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":682,"enrollmentInfo":683,"targetDuration":4,"studyType":87,"phases":685,"briefSummary":687,"conditions":688,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":692,"startDateStruct":694,"completionDateStruct":695,"leadSponsor":696,"locationsCount":697},"100554192","phase-4-pvp-guided-decongestive-therapy-in-hf-2-100554192","NCT06495892","PVP-Guided Decongestive Therapy in HF 2","Peripheral Venous Pressure-Guided Decongestive Therapy in Heart Failure 2","PERIPHERAL-HF2","Inclusion criteria\n\n* Hospitalization for heart failure (de novo or decompensated chronic heart failure) irrespective of left ventricular ejection fraction\n* Age 18-99\n* Accept to participate\n\nExclusion criteria\n\n* A prior history of upper extremity venous disease\n* Serum creatinine ≥ 3.5 mg\u002FdL\n* Severe stenotic valvular disease\n* Hypertrophic obstructive cardiomyopathy\n* Withdrawal of consent\n* Indwelling central venous catheter,\n* Implanted left ventricular assist device\n* History of heart transplantation\n* Clinical diagnosis of cardiogenic shock\n* Any right-to-left shunt","99 Years",{"count":684,"type":23},650,[686],"PHASE4","The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.",[689,690,691],"Heart Failure","Congestion","Congestive Heart Failure",{"date":693,"type":40},"2024-12-04",{"date":671,"type":40},{"date":133,"type":23},{"name":46,"class":47},16,""]