[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bahaa Bou Dargham\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":89},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100651704","therapeutic-effects-of-music-on-procedural-outcomes-100651704",false,"NCT07763860","Therapeutic Effects of Music on Procedural Outcomes","Effect of Intra-Procedural Low-Tempo Instrumental Music Plus Standard Sedation Versus Standard Sedation Alone on Sedative Requirements in Adults Undergoing Gastroscopy and\u002For Colonoscopy: a Single-Center, Parallel-Group, Randomized Superiority Trial With Blinded Outcome Assessors and Statisticians","TEMPO","Inclusion Criteria:\n\n* Age ≥18 years.\n* Scheduled for elective gastroscopy (upper gastrointestinal endoscopy), colonoscopy, or both under procedural sedation.\n* Able to provide written informed consent.\n\nExclusion Criteria:\n\n* Emergency or urgent endoscopic procedure.\n* Hearing impairment that prevents adequate perception of the standardized test audio through the study headphones.\n* American Society of Anesthesiologists (ASA) Physical Status IV or higher.\n* Cognitive impairment, altered mental status, or another condition that prevents provision of informed consent or reliable completion of study assessments.\n* Any condition that prevents safe or appropriate use of the study headphones.","ALL","18 Years",{"count":20,"type":21},180,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will evaluate whether listening to low-tempo instrumental music during gastroscopy and\u002For colonoscopy can reduce the amount of sedative medication needed during the procedure. Adults undergoing elective gastroscopy and\u002For colonoscopy with sedation will be randomly assigned to one of two groups. One group will listen to low-tempo instrumental music (60-80 beats per minute) through headphones during the procedure in addition to receiving standard sedation. The other group will receive standard sedation without music.\n\nThe main outcome of the study is the amount of sedative medication required during the procedure. The study will also compare pain after the procedure, time until discharge, patient satisfaction, and changes in heart rate and blood pressure between the two groups. The researchers hypothesize that patients who listen to low-tempo music will require less sedative medication and may have improved recovery and patient-reported outcomes compared with patients receiving standard sedation alone.",[27,28,29],"Procedural Sedation","Gastrointestinal Endoscopy","Music Intervention",[31,32,33,34,27,35,36,37,38,39],"Music","Low-Tempo Music","Gastroscopy","Colonoscopy","Sedation","Propofol","Pain","Patient Satisfaction","Recovery Time","RECRUITING","2026-08-09",{"date":43,"type":44},"2026-08-13","ACTUAL",{"date":46,"type":21},"2026-08",{"date":48,"type":21},"2026-10",{"name":50,"class":51},"Bahaa Bou Dargham","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":52},"100618093","childrens-laughter-and-fun-yoga-as-adjunctive-pain-relief-following-chemotherapy-100618093","NCT07327138","Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.","A Multi-center, Assessor-blinded, Randomized, Parallel Group, Superiority Trial Evaluating the Efficacy of Home-based Laughter and Fun Yoga as an Adjunct for Pain Reduction in Pediatric Oncology Patients Receiving Chemotherapy.","CLAP","Inclusion Criteria:\n\n* Children aged 2-10 years.\n* Medically diagnosed with acute lymphoblastic leukemia (ALL) and currently receiving chemotherapy that includes dexamethasone pulses during the maintenance phase.\n* Clinically stable and able to participate in gentle, low-intensity yoga movements as determined by the treating physician.\n* At least one parent or legal guardian willing and able to supervise and participate in the home-based intervention sessions.\n* Written informed consent from parent\u002Flegal guardian, with age-appropriate assent from the child.\n\nExclusion Criteria:\n\n* Recent major surgery (within the past 2 weeks) that may limit safe participation in gentle activity.\n* Severe uncontrolled medical conditions (unstable vital signs, decompensated cardiac or respiratory disease, uncontrolled epilepsy) that may place the child at risk during light movement or laughter.\n* Severe visual, hearing, or cognitive impairment preventing engagement with video-based instructions and exercises.\n* Physical limitations or musculoskeletal injuries that prevent participation in the intervention.\n* Any other condition that, in the judgment of the treating physician, would interfere with safe participation or adherence.\n* Currently enrolled in another interventional clinical trial for pain management.","2 Years","10 Years",{"count":64,"type":21},60,[24],"The goal of this clinical trial is to learn if a home-based program that combines laughter and fun yoga can help lower pain in children receiving chemotherapy. The study focuses on children with acute lymphoblastic leukemia who experience pain during treatment with chemotherapy and steroids.\n\nThe main questions this study aims to answer are:\n\n1. Does adding laughter and fun yoga to usual care lower pain levels in children receiving chemotherapy?\n2. Does this program reduce the need for strong pain medicines, such as opioids?\n3. Does the program help improve mood, anxiety, and sleep during treatment?\n\nResearchers will compare children who receive laughter and fun yoga plus usual care with children who receive usual care alone to see if the program works.\n\nParticipants will:\n\n1. Be randomly assigned to either the laughter and fun yoga group or the usual care group\n2. Take part in the study during a 6-day period after receiving their chemotherapy treatment\n3. Have their pain measured once each day using a child-friendly pain scale\n4. Have parents answer short questions about pain medicine use, mood, anxiety, and sleep\n\nThe laughter and fun yoga activities are gentle, safe, and designed to be done at home with the help of a parent. All participants will continue to receive their regular medical care throughout the study.",[68],"Acute Lymphoblastic Leukemia ALL",[70,71,72,73,74,75,76,77,78,79,80],"Acute Lymphoblastic Leukemia","Chemotherapy","Steroids","Pediatric Oncology","Pain Management","Cancer-related Pain","Laughter Therapy","Yoga Therapy","Non-pharmacological Intervention","Home-based Intervention","Supportive Cancer Care","2025-12-25",{"date":83,"type":44},"2026-01-08",{"date":85,"type":44},"2025-10-15",{"date":87,"type":21},"2026-12",{"name":50,"class":51},""]