[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bojan Kovacevic\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100658194","pancreatic-endoscopic-ultrasound-guided-radiofrequency-for-inoperable-carcinoma-treatment-100658194",false,"NCT07850336","Pancreatic Endoscopic Ultrasound-guided RadioFrequency for Inoperable Carcinoma Treatment","Pancreatic Endoscopic Ultrasound-guided RadioFrequency for Inoperable Carcinoma Treatment (PERFECT Study)","PERFECT","Inclusion Criteria:\n\n* Adult habile patients with a signed informed consent\n* Histologically confirmed pancreatic carcinoma ≤5 cm in largest diameter\n* ECOG performance status 0-2\n* Patients not eligible for curative-intended surgical treatment due to:\n\nAdvanced (unresectable) disease, or Unsuitability for surgery due to comorbidities or poor performance status, or Patient preference to decline surgery\n\nExclusion Criteria:\n\n* Metastatic disease\n* Uncorrected coagulopathy (INR ≥1.5 or thrombocyte count \\\u003C 50 mia\u002FL)\n* Altered anatomy or interposition of major vessels precluding safe EUS-RFA\n* Active untreated infection or pancreatitis\n* Life expectancy \\\u003C3 months\n* Prior local ablative treatment interfering with outcome","ALL","18 Years",{"count":20,"type":21},56,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to evaluate whether endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) affects survival in patients with inoperable pancreatic carcinoma. By using a prospective single-arm design with historical controls, this study aims to generate clinically relevant data while minimizing the number of patients exposed to experimental treatment. The findings may support future integration of EUS-RFA into standard care for this high-need patient population.",[27],"Pancreatic Ductal Adenocarcinoma (PDAC)",[29,30,31],"EUS-RFA","Endoscopic Ultrasound-Guided Radiofrequency Ablation","Locally Advanced Pancreatic Cancer","NOT_YET_RECRUITING","2026-09-24",{"date":35,"type":36},"2026-09-30","ACTUAL",{"date":38,"type":21},"2026-10-01",{"date":40,"type":21},"2030-12",{"name":42,"class":43},"Bojan Kovacevic","OTHER",""]