[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Borna Farhoomand\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100652497","multi-segmental-spinal-manual-therapy-in-women-with-episodic-migraine-100652497",false,"NCT07774286","Multi-Segmental Spinal Manual Therapy in Women With Episodic Migraine","Multi-segmental Spinal Manual Therapy for Pain, Central Sensitization, and Sensorimotor Control in Women With Episodic Migraine: A Case Series.","Inclusion Criteria:\n\n* Female patients aged 18-30 years,\n* Diagnosis of episodic migraine established by a specialist neurologist,\n* Headache frequency of \\\u003C15 days per month,\n* Pain intensity score of ≥40 mm on the Visual Analog Scale (VAS),\n* Absence of any diagnosed psychiatric disorders,\n* Literacy (ability to read and write),\n* Ability to communicate effectively without language or cognitive barriers,\n* Voluntary participation confirmed by signed written informed consent.\n\nExclusion Criteria:\n\n* History of communication disorders or neuromusculoskeletal diseases that impede assessment procedures,\n* Headache frequency exceeding 15 days per month,\n* Diagnosis of other primary or secondary headache types (e.g., cervicogenic headache, tension-type headache),\n* Pregnancy,\n* Diagnosis of fibromyalgia syndrome or myofascial pain syndrome,\n* Diagnosis of systemic rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus),\n* Diagnosis or presence of symptoms related to spinal disc disorders (e.g., disc herniation, disc prolapse),\n* History of whiplash or similar cervical\u002Fhead trauma,\n* Diagnosis or presence of symptoms associated with temporomandibular joint dysfunction (TMD),\n* Having received physical therapy within the last 3 months,\n* Having undergone anesthetic nerve block procedures within the last 6 months,\n* Receiving any prophylactic or interventional migraine therapy other than acute analgesics,\n* Self-reported history or presence of malignancy.","FEMALE","18 Years","30 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to evaluate the clinical effects of multi-segmental spinal manual therapy on pain intensity, central sensitization, and sensorimotor control in women diagnosed with episodic migraine.\n\nParticipants receive 10 sessions of a comprehensive manual therapy intervention targeting the cervical, thoracic, lumbar, and sacral regions over a 2-week period. Clinical outcomes-including headache pain intensity, sensorimotor dysfunction, headache-related disability, and cutaneous allodynia-are evaluated at baseline, immediately after the 2-week treatment, and at a 1-month follow-up.\n\nThis study aims to investigate whether addressing multiple spinal segments with manual therapy improves clinical symptoms, spinal motor control, and central pain processing in female individuals with episodic migraine.",[27],"Migraine Disorders",[29,30,31,32,33,34,35],"Episodic Migraine","Manual Therapy","Spinal Mobilization","Central Sensitization","Sensorimotor Control","Musculoskeletal Manipulations","Cutaneous Allodynia","NOT_YET_RECRUITING","2026-08-16",{"date":39,"type":40},"2026-08-19","ACTUAL",{"date":42,"type":21},"2026-09-01",{"date":44,"type":21},"2026-12-30",{"name":46,"class":47},"Borna Farhoomand","OTHER",""]