[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bovita Labs, LLC\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":53},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100658950","colostrum-and-gut-health-100658950",false,"NCT07856979","Colostrum and Gut Health","A Randomized Controlled Trial to Examine the Impact of Two Colostrum Doses on Gut Health","Inclusion Criteria:\n\n* Adults aged 30 to 60 years at the time of enrollment.\n* Self-reported suboptimal digestive function (e.g., bloating, irregular bowel habits, discomfort) and\u002For suboptimal immune function (e.g., frequent colds, low energy) during the previous 4 weeks.\n* Willing and able to consume a powdered supplement (3-6 g) mixed in liquid once daily.\n* Own a compatible iOS or Android smartphone with internet access.\n* Willing to connect a compatible wearable device (Apple Watch or Oura Ring) or Apple Health\u002FGoogle Fit data source for passive data collection.\n* Complete at least 30 minutes of physical activity or exercise most days of the week.\n* Able to provide informed consent and comply with the study protocol for 20 weeks.\n* Able to read and understand English.\n* Willing to provide informed consent electronically.\n\nExclusion Criteria:\n\n* Diagnosis of inflammatory bowel disease, Crohn's disease, ulcerative colitis, or other malabsorptive gastrointestinal disease or condition.\n* Diagnosis of celiac disease or known severe allergy to dairy-derived or bovine colostrum products.\n* Currently pregnant, breastfeeding, or planning pregnancy during the study period.\n* Current or within the previous 30 days use of immunosuppressive medications, systemic corticosteroids, or biologic agents.\n* Use of bovine colostrum or colostrum-containing supplements within the previous 30 days.\n* Regular use of probiotic or prebiotic supplements within 14 days of enrollment. Does not participate in at least 30 minutes of physical activity or exercise most days of the week.\n* Major gastrointestinal surgery within the previous 12 months.\n* Autoimmune condition requiring immunomodulatory treatment.\n* Participation in another interventional clinical study within 30 days of enrollment.\n* Body mass index greater than 35.0 kg\u002Fm².\n* Known or severe lactose intolerance or milk protein allergy.",true,"ALL","30 Years","60 Years",{"count":21,"type":22},140,"ESTIMATED","INTERVENTIONAL",[25],"NA","The primary objective of this study is to evaluate changes in participant-reported gastrointestinal function over a 16-week intervention period and a 4-week non-supplementation period (20 weeks total) following daily consumption of two different doses of colostrum in comparison to a placebo.\n\nSecondary objectives include evaluation of digestive comfort, immune resilience, energy levels, sleep quality, hsCRP, metabolic panel, microbiome status and function, and hair and skin health.\n\nExploratory objectives include the collection of physical activity status and pulse rate variability at specified timepoints to provide supportive contextual information alongside participant-reported outcomes.",[28],"Gastrointestinal Health",[30,31,28,32,33,34,35,36,37,38,39,40],"Bovine Colostrum","Colostrum","Gut Health","Digestive Health","Gut Microbiome","Immune Resilience","Sleep","Energy","Dietary Supplement","Skin health","Hair health","NOT_YET_RECRUITING","2026-09-28",{"date":44,"type":45},"2026-10-05","ACTUAL",{"date":47,"type":22},"2026-09-04",{"date":49,"type":22},"2028-09-01",{"name":51,"class":52},"Bovita Labs, LLC","INDUSTRY",""]