[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Clínica Dávila\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":115},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,82],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100650337","phase-4-swap-anesthetic-versus-continuous-desflurane-in-adults-undergoing-bariatric-surgery-100650337",false,"NCT07748247","Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery","Desflurane Versus Sevoflurane-Desflurane Swap in Adults Undergoing Bariatric Surgery: A Randomized Non-Inferiority Trial on Extubation Time","SWAP","Inclusion Criteria:\n\n* Age 18 years or older.\n* Scheduled for elective laparoscopic gastric bypass surgery.\n* Body mass index between 30 and 50 kg\u002Fm².\n* American Society of Anesthesiologists physical status II or III.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Surgical procedure lasting less than 2 hours.\n* Body mass index greater than 50 kg\u002Fm².\n* Significant cardiac disease.\n* Moderate or severe obstructive respiratory disease, including uncontrolled asthma or chronic obstructive pulmonary disease.\n* Pregnancy or breastfeeding.\n* Known allergy or contraindication to medications used during the intraoperative period.\n* Personal or family history of malignant hyperthermia.\n* Active illicit drug use or substance dependence.\n* Advanced chronic kidney disease, defined as an estimated glomerular filtration rate below 60 mL\u002Fmin.\n* Myasthenia gravis or another neuromuscular junction disorder.\n* Severe cognitive or psychiatric disorder.\n* Refusal to participate or withdrawal of informed consent at any time.","ALL","18 Years",{"count":20,"type":21},82,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.",[27,28],"Obesity","Bariatric Surgery",[30,31,32,28,33,27,34,35,36,37],"Desflurane","Sevoflurane","General Anesthesia","Extubation Time","Laparoscopic Gastric Bypass","Randomized Trial","Non-Inferiority Trial","Patient State Index","NOT_YET_RECRUITING","2026-08-03",{"date":41,"type":42},"2026-08-05","ACTUAL",{"date":39,"type":21},{"date":45,"type":21},"2027-04",{"name":47,"class":48},"Clínica Dávila","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":49},"100649895","acceleromyography-versus-electromyography-for-neuromuscular-recovery-assessment-at-the-end-of-surgery-100649895","NCT07739862","Acceleromyography Versus Electromyography for Neuromuscular Recovery Assessment at the End of Surgery","Concordance Between Acceleromyography and Electromyography for Assessment of Neuromuscular Recovery at the End of Surgery","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia.\n* Administration of non-depolarizing neuromuscular blocking agents.\n* Written informed consent provided.\n\nExclusion Criteria:\n\n* Pre-existing neuromuscular disease.\n* Upper extremity abnormalities preventing neuromuscular monitoring.\n* Contraindications to neuromuscular monitoring.\n* Refusal or inability to provide informed consent.",{"count":58,"type":21},70,"OBSERVATIONAL","This prospective observational study aims to evaluate the agreement between acceleromyography and electromyography for measuring train-of-four (TOF) ratio at the end of surgery before reversal of neuromuscular blockade. Adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia with non-depolarizing neuromuscular blockade will undergo simultaneous TOF measurements using both monitoring methods. The study will assess the agreement between the two techniques, estimate measurement bias and limits of agreement, and determine the frequency of clinically relevant disagreement that could affect assessment of neuromuscular recovery and safe extubation.",[62,63],"Neuromuscular Blockade","Cholecystectomy",[65,66,67,68,69,70,32,71,72,73],"Acceleromyography","Electromyography","Train-of-Four","TOF Ratio","Neuromuscular Monitoring","Residual Neuromuscular Blockade","Laparoscopic Cholecystectomy","Bland-Altman Analysis","Diagnostic Agreement","2026-07-28",{"date":76,"type":42},"2026-07-31",{"date":78,"type":21},"2026-08",{"date":80,"type":21},"2027-01",{"name":47,"class":48},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":93,"conditions":94,"keywords":98,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":49},"100649440","analgesia-with-transdermal-buprenorphine-patch-in-adults-undergoing-video-assisted-thoracoscopic-surgery-100649440","NCT07733128","Analgesia With Transdermal Buprenorphine Patch in Adults Undergoing Video-Assisted Thoracoscopic Surgery","Analgesia With a 5 mcg\u002FHour Transdermal Buprenorphine Patch as Part of Multimodal Analgesia in Adults Undergoing Unilateral Video-Assisted Thoracoscopic Surgery: A Triple-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Scheduled for elective unilateral video-assisted thoracoscopic surgery (VATS).\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Able to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to buprenorphine or any component of the transdermal patch.\n* Chronic opioid use before surgery.\n* Severe hepatic impairment.\n* Pregnancy or breastfeeding.\n* Inability to complete postoperative pain assessments.\n* Any condition that, in the investigator's opinion, could interfere with study participation or outcome assessment.",{"count":90,"type":21},90,[92],"NA","Postoperative pain remains a major challenge after video-assisted thoracoscopic surgery (VATS), despite the use of multimodal analgesia. This randomized, triple-blind, placebo-controlled clinical trial will evaluate whether adding a 5 mcg\u002Fhour transdermal buprenorphine patch to the standard multimodal analgesic regimen reduces postoperative pain in adults undergoing unilateral VATS. Participants will be randomly assigned to receive either transdermal buprenorphine or placebo in addition to standard analgesia. Postoperative pain will be assessed at 24, 48, and 72 hours and 7 days after surgery. Secondary outcomes include opioid rescue requirements, length of hospital stay, postoperative nausea and vomiting, pruritus, and urinary retention.",[95,96,97],"Postoperative Pain","Thoracic Surgery","Video-Assisted Thoracoscopic Surgery",[99,100,101,97,102,95,103,96,104,105],"Buprenorphine","Transdermal Patch","Multimodal Analgesia","VATS","Randomized Controlled Trial","Acute Pain","Opioid Analgesia","RECRUITING","2026-07-24",{"date":109,"type":42},"2026-07-29",{"date":111,"type":42},"2026-03-01",{"date":113,"type":21},"2027-07",{"name":47,"class":48},""]