[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"DINA KEUMALA SARI\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":114},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,70,93],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100648413","the-effect-of-channa-striata-and-curcuma-supplementation-on-nutritional-status-interleukin-6-levels-and-quality-of-life-in-patients-with-breast-cancer-100648413",false,"NCT07722156","The Effect of Channa Striata and Curcuma Supplementation on Nutritional Status, Interleukin-6 Levels, and Quality of Life in Patients With Breast Cancer.","CCBreast","Inclusion Criteria:\n\n* Female patients with breast cancer aged ≥18 years who were undergoing chemotherapy.\n* Patients with a body mass index (BMI) of 18-29 kg\u002Fm².\n* Patients currently receiving chemotherapy for breast cancer.\n* Patients with serum albumin levels of 2.0-3.5 g\u002FdL.\n* Patients who were able to consume oral food and were willing to participate in the study by providing written informed consent.\n\nExclusion Criteria:\n\n* Patients with chronic kidney disease, renal failure, or kidney infection.\n* Patients with a known allergy to fish or Channa striata (snakehead fish) albumin-derived products.\n* Patients receiving other protein or amino acid supplements during the study period.\n* Patients who were non-compliant or discontinued the intervention before completion of the study.","FEMALE",{"count":18,"type":19},76,"ESTIMATED","INTERVENTIONAL",[22],"NA","Breast cancer is frequently accompanied by chronic inflammation, malnutrition, and reduced quality of life, all of which may compromise treatment response and clinical outcomes. Nutritional interventions with immunomodulatory and anti-inflammatory properties have the potential to improve these conditions. Channa striata is rich in high-quality protein, albumin, and essential amino acids that support nutritional recovery and tissue repair, while Curcuma contains curcumin, a bioactive compound with well-established anti-inflammatory and antioxidant effects. This study aims to evaluate the effect of combined Channa striata and Curcuma supplementation on nutritional status, serum interleukin-6 (IL-6) levels, and quality of life in patients with breast cancer undergoing treatment. The findings are expected to provide evidence for the use of this nutritional supplementation as a complementary strategy to improve clinical outcomes, reduce systemic inflammation, and enhance the overall well-being of breast cancer patients.",[25],"Breast Cancer",[27,28],"Breast cancer; Channa striata; Curcuma; Nutritional status; Interleukin-6 (IL-6); Quality of life; Nutritional supplementation; Inflammation.","Breast cancer, Channa striata Curcuma, Interleukin-6, Quality of life","NOT_YET_RECRUITING","2026-07-19",{"date":32,"type":33},"2026-07-23","ACTUAL",{"date":35,"type":19},"2026-08-01",{"date":37,"type":19},"2027-01-31",{"name":39,"class":40},"DINA KEUMALA SARI","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":20,"phases":52,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":67,"leadSponsor":69,"locationsCount":41},"100648123","the-effects-of-structured-lactation-nutrition-education-and-dali-ni-horbo-supplementation-on-maternal-nutritional-intake-breastfeeding-practices-infant-growth-and-gut-microbiota-a-randomized-controlled-trial-100648123","NCT07718087","The Effects of Structured Lactation Nutrition Education and Dali ni Horbo Supplementation on Maternal Nutritional Intake, Breastfeeding Practices, Infant Growth, and Gut Microbiota: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Lactating mothers aged 18-40 years.\n* Having a healthy, singleton infant aged 0-1 month at enrollment.\n* Residing within the service areas of the participating primary healthcare centers in Medan, Indonesia.\n* Currently breastfeeding and intending to continue breastfeeding throughout the study period.\n* Able to consume Dali ni Horbo and willing to follow the assigned intervention.\n* Willing to participate in all study assessments, including dietary assessment, anthropometric measurements, and infant stool collection.\n* Able to communicate effectively and complete the study questionnaires.\n* Willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Mothers or infants with medical conditions that may significantly affect breastfeeding, maternal nutritional status, nutrient metabolism, or infant growth.\n* Mothers with severe postpartum complications or conditions requiring hospitalization.\n* Infants with congenital abnormalities, gastrointestinal disorders, metabolic diseases, severe infections, or other conditions affecting feeding or growth.\n* Infants born preterm or with low birth weight, according to the study protocol.\n* Mothers with a known allergy or intolerance to buffalo milk, cow's milk, or dairy products.\n* Mothers following a medically prescribed restrictive diet that could affect the study outcomes.\n* Current participation in another nutritional or clinical intervention study.\n* Use of nutritional supplements, probiotics, antibiotics, or other treatments that may substantially affect maternal nutrient intake or infant gut microbiota, unless permitted by the study protocol.\n* Inability or unwillingness to comply with the intervention and follow-up procedures.","18 Years","40 Years",{"count":51,"type":19},50,[22],"This randomized controlled trial aims to evaluate the effects of structured lactation nutrition education combined with Dali ni Horbo supplementation on maternal dietary intake, breastfeeding practices, infant growth, and infant gut microbiota. Lactating mothers with healthy infants aged 0-1 month will be recruited from selected primary healthcare centers in Medan, Indonesia, and assigned to an intervention or control group. The intervention group will receive structured nutrition education and daily Dali ni Horbo, a traditional Batak fermented buffalo milk product, while the control group will receive standard care. Maternal energy and nutrient intake, nutritional knowledge and attitudes, exclusive breastfeeding practices, maternal and infant anthropometric measurements, intervention adherence, adverse effects, and infant fecal microbiota composition will be assessed before and after the intervention. This study is expected to determine whether integrating nutrition education with a nutrient-dense local food can improve maternal nutritional adequacy, support exclusive breastfeeding, promote optimal infant growth, and beneficially influence early-life gut microbiota.",[55,56],"Maternity Care","Nutrition Education",[58,59,60,61,62],"Lactation nutrition","Dali ni Horbo","Exclusive breastfeeding","Infant growth","Infant gut microbiota","2026-07-16",{"date":65,"type":33},"2026-07-21",{"date":35,"type":19},{"date":68,"type":19},"2026-10-31",{"name":39,"class":40},{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":76,"minAge":48,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":20,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":41},"100646151","the-effect-of-structured-medical-nutrition-therapy-on-systemic-inflammation-index-in-patients-with-schizophrenia-receiving-antipsychotic-therapy-100646151","NCT07696000","The Effect of Structured Medical Nutrition Therapy on Systemic Inflammation Index in Patients With Schizophrenia Receiving Antipsychotic Therapy","Inclusion Criteria:\n\nAdults aged 18-60 years. Diagnosed with schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).\n\nReceiving stable antipsychotic therapy for at least 4 weeks before enrollment. Hospitalized at Prof. Dr. M. Ildrem Psychiatric Hospital during the study period.\n\nAble to consume an oral diet. Willing to participate and provide written informed consent (or consent provided by a legally authorized representative when applicable).\n\nExclusion Criteria:\n\nAcute infection, autoimmune disease, malignancy, or other inflammatory conditions that may influence the Systemic Inflammation Index (SII).\n\nChronic liver disease, end-stage renal disease, or severe heart failure. Pregnancy or breastfeeding. Current use of systemic corticosteroids, immunosuppressive agents, or anti-inflammatory medications that could affect inflammatory biomarkers.\n\nReceiving enteral or parenteral nutrition. Participation in another interventional clinical trial within the previous 3 months.\n\nIncomplete clinical or laboratory data. Inability to complete the intervention or follow-up assessments.","ALL","60 Years",{"count":79,"type":19},100,[22],"Patients with schizophrenia receiving long-term antipsychotic therapy are at increased risk of chronic low-grade inflammation and metabolic disturbances, which contribute to poor physical health outcomes and increased cardiovascular morbidity. Structured Medical Nutrition Therapy (MNT), consisting of individualized nutrition assessment, dietary intervention, nutrition education, and regular monitoring, has the potential to improve dietary quality and modulate systemic inflammation. This study aims to evaluate the effect of Structured Medical Nutrition Therapy on the Systemic Inflammation Index (SII), a novel inflammatory biomarker derived from neutrophil, lymphocyte, and platelet counts, in patients with schizophrenia receiving antipsychotic therapy. It is hypothesized that patients receiving structured MNT will demonstrate a greater reduction in SII compared with those receiving standard nutritional care, supporting the integration of evidence-based nutritional interventions into the comprehensive management of schizophrenia to improve metabolic and inflammatory outcomes.",[83],"Schizophrenia \u002F Schizoaffective Disorder","RECRUITING","2026-07-05",{"date":87,"type":33},"2026-07-10",{"date":89,"type":33},"2026-07-01",{"date":91,"type":19},"2026-10-30",{"name":39,"class":40},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":76,"minAge":4,"maxAge":4,"enrollmentInfo":100,"targetDuration":4,"studyType":20,"phases":102,"briefSummary":103,"conditions":104,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":41},"100624373","effects-of-intermittent-fasting-variations-on-metabolic-inflammatory-and-nutrigenomic-profiles-in-prediabetes-a-randomized-controlled-trial-100624373","NCT07408791","Effects of Intermittent Fasting Variations on Metabolic, Inflammatory, and Nutrigenomic Profiles in Prediabetes: A Randomized Controlled Trial","The Effect of Intermittent Fasting Variations on Nutrigenomic Profile, Changes in Metabolic and Inflammatory Parameters, and Body Composition in Patients With Prediabetes","Inclusion Criteria:\n\n1. Patients with prediabetes, defined according to ADA criteria (fasting plasma glucose 100-125 mg\u002FdL or 2-hour postprandial glucose 140-199 mg\u002FdL).\n2. Willing to follow the fasting\u002Fdiet intervention protocol for 4-6 weeks (depending on the study duration).\n3. Signing informed consent and willing to be randomized into one of 3 intervention groups (Monday-Thursday Fasting\u002F5:2, Alternate-Day Fasting\u002FADF, or Time-Restricted Fasting\u002FIF).\n\nExclusion Criteria\n\n1. Diagnosis of type 2 diabetes mellitus.\n2. Currently undergoing antidiabetic drug therapy (e.g., metformin, sulfonylurea, insulin).\n3. Has a severe chronic disease (kidney failure, liver failure, heart failure, or eating disorder).\n4. Pregnancy or breastfeeding.\n5. History of eating disorders (anorexia nervosa, bulimia nervosa, or binge eating disorder).\n6. Taking medications that affect glucose metabolism (e.g., systemic steroids, atypical antipsychotics, etc.). Diagnosis of type 2 diabetes",{"count":101,"type":19},120,[22],"Prediabetes is a metabolic condition associated with increased risk of type 2 diabetes and cardiovascular disease. Intermittent fasting (IF) has emerged as a potential dietary intervention to improve metabolic health, yet comparative evidence among different IF patterns remains limited.\n\nThis randomized controlled trial aims to evaluate the effects of three intermittent fasting regimens-5:2 fasting, alternate-day fasting, and time-restricted feeding-compared with a control diet on metabolic parameters, inflammatory markers, body composition, and nutrigenomic profiles in adults with prediabetes.",[105],"Pre Diabetic","2026-02-06",{"date":108,"type":33},"2026-02-13",{"date":110,"type":19},"2026-02",{"date":112,"type":19},"2026-06-30",{"name":39,"class":40},""]