[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Diansan Su\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":78},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100620836","video-guided-versus-conventional-right-sided-double-lumen-tubes-for-one-lung-ventilation-in-thoracoscopic-surgery-100620836",false,"NCT07362797","Video-guided Versus Conventional Right-sided Double-Lumen Tubes for One-Lung Ventilation in Thoracoscopic Surgery","Video-guided Versus Conventional Right-sided Double-Lumen Tubes for One-Lung Ventilation in Thoracoscopic Surgery: A Multicentre Randomized Controlled Trial","RIGHT-VDLT","\\*\\*Inclusion Criteria:\\*\\*\n\n1. Adults aged 18 years or older.\n2. American Society of Anesthesiologists physical status I-III.\n3. Scheduled for elective thoracoscopic surgery requiring one-lung ventilation with a right-sided double-lumen tube.\n4. Able to provide written informed consent.\n\n\\*\\*Exclusion Criteria:\\*\\*\n\n1. Contraindication to placement of a right-sided double-lumen tube, including a lesion involving the right main bronchus that precludes its use.\n2. Known tracheobronchial anatomical abnormality that may interfere with right-sided double-lumen tube placement or lung isolation.\n3. Known or anticipated difficult airway.\n4. Requirement for rapid-sequence induction.\n5. Emergency surgery.\n6. Severe respiratory instability that, in the investigator's judgement, makes participation unsafe.\n7. Concurrent participation in another interventional clinical trial that could interfere with the present study.","ALL","18 Years",{"count":20,"type":21},566,"ESTIMATED","INTERVENTIONAL",[24],"NA","This multicentre randomised controlled trial compares a video-guided right-sided double-lumen tube with a conventional right-sided double-lumen tube in adults undergoing elective thoracoscopic surgery requiring one-lung ventilation. The video-guided tube incorporates an integrated camera that provides continuous airway visualisation during initial placement and intraoperative monitoring.\n\nParticipants will be randomly assigned in a 1:1 ratio to receive one of the two tubes. Final tube position after initial placement will be confirmed by fibreoptic bronchoscopy in both groups. During one-lung ventilation, additional fibreoptic bronchoscopy will be performed only when clinically indicated or according to predefined rescue criteria.\n\nThe primary outcome is successful initial right-sided double-lumen tube placement. Secondary outcomes include right upper-lobe bronchial obstruction, intraoperative tube displacement, hypoxemia during one-lung ventilation, requirement for rescue fibreoptic bronchoscopy, time to satisfactory tube positioning, quality of operative lung collapse, and the number of intraoperative tube repositioning events.\n\nParticipants and outcome assessors will remain blinded to treatment allocation, whereas the anaesthesiologist performing intubation cannot be blinded because of the distinct visual and operational characteristics of the two devices. The study aims to determine whether continuous airway visualisation improves the effectiveness and stability of right-sided double-lumen tube management during thoracoscopic surgery.",[27,28,29],"Thoracoscopic Surgery","Double Lumen Tube Intubation","One-Lung Ventilation",[31,32,33,34,35,36],"Video-guided right-sided double-lumen tube","Right-sided double-lumen tube","One-lung ventilation","Fibreoptic bronchoscopy","Thoracoscopic surgery","Lung isolation","RECRUITING","2026-08-13",{"date":40,"type":41},"2026-08-17","ACTUAL",{"date":43,"type":41},"2026-05-30",{"date":45,"type":21},"2027-03-01",{"name":47,"class":48},"Diansan Su","OTHER",3,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":56,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":49},"100618739","the-efficacy-of-remimazolam-on-incidence-of-hypoxia-during-sedated-transvaginal-oocyte-retrieval-a-multicenter-randomized-controlled-trial-100618739","NCT07335536","The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval: A Multicenter Randomized Controlled Trial.","Inclusion Criteria:\n\n* Subjects aged 18 to 50 years planning to undergo painless oocyte retrieval\n* Subjects classified as American Society of Anesthesiologists (ASA) physical status I-II\n\nExclusion Criteria:\n\n* Subjects with contraindications to general anesthesia, acute or severe cardiovascular disease history, acute upper respiratory infection, chronic obstructive pulmonary disease (COPD), asthma attacks, or uncontrolled hypertension\n* Subjects with alcohol abuse\n* Subjects with severe hepatic or renal insufficiency, severe cardiovascular disease, or psychiatric disorder history\n* Subjects with hearing impairment preventing communication\n* Subjects with a history of long-term sedative or opioid use, or allergies to benzodiazepines, flumazenil, opioids and their antidotes, propofol, eggs, or soy products\n* Subjects with SpO2 \\\u003C 95% while breathing room air after entering the room","FEMALE","50 Years",{"count":59,"type":21},400,[24],"Hypoxia is the most common adverse reaction during sedation outside the operating room.Exploring novel drug combinations to reduce the incidence of hypoxia during sedation in patients undergoing transvaginal oocyte retrieval procedures enhances patient safety and lowers perioperative adverse event rates. This multicenter, prospective, randomized, controlled clinical study will compare the hypoxia incidence rate of the remimazolam-alfentanil combination against the commonly used propofol-alfentanil combination.",[63,64,65],"Hypoxia","Infertility","Infertility Assisted Reproductive Technology",[63,67,68,69],"oocyte retrieval","remimazolam","general anesthesia","2026-01-01",{"date":72,"type":41},"2026-01-13",{"date":74,"type":41},"2025-10-20",{"date":76,"type":21},"2026-12-30",{"name":47,"class":48},""]