[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Duke Kunshan University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":133},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,53,85,108],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100652941","ceeec-ii-a-12-week-physical-and-cognitive-enrichment-extension-study-in-older-stroke-survivors-with-multimorbidity-100652941",false,"NCT07778771","CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity","A 12-Week, Multicenter, Open-Label, 2×2 Factorial, Cluster-Assigned Extension Study of Upgraded Physical and AI-Enabled Large-Screen Cognitive Enrichment for Older Stroke Survivors With Multimorbidity in Kunshan, China","CEEEC-II","Inclusion Criteria:\n\n* Completed the endpoint assessment of the preceding CEEEC Phase I trial (NCT06975501) and remains under management at a participating community health service station in Kunshan.\n* Age 60 years or older.\n* Hospital-confirmed ischemic or hemorrhagic stroke in a stable stage, with no new or worsening neurological deficit within the previous 3 months.\n* Registered hypertension and\u002For type 2 diabetes mellitus; other comorbid conditions are permitted.\n* Willing and able to participate in the 12-week community-based extension program and complete baseline and endpoint assessments.\n* Able to travel to the community site independently or with a cane or walker; not dependent on a wheelchair for attendance.\n* Short Physical Performance Battery total score \\>=3, or able to maintain a supported side-by-side standing position for 10 seconds when the total score is \\\u003C3.\n* Able to communicate in Mandarin Chinese or the Kunshan dialect and able to recognize Arabic numerals.\n* Corrected vision sufficient to identify large characters at approximately 40 cm and at least one upper limb able to complete touchscreen selection.\n* Resides in the participating community and has no plan to move away during the study period.\n* Provides written informed consent specifically for CEEEC-II.\n\nExclusion Criteria:\n\n* Life-threatening disease or another condition associated with an expected survival of less than 6 months.\n* A new stroke, transient ischemic attack, acute coronary event, or hospitalization for decompensated heart failure within the previous 3 months.\n* Uncontrolled resting blood pressure (systolic \\>=180 mmHg or diastolic \\>=110 mmHg after repeated measurement) until clinically reassessed and controlled.\n* Extreme glycemic instability, including fasting blood glucose \\>16.7 mmol\u002FL or severe hypoglycemia requiring assistance within the previous month, until clinically reassessed.\n* An absolute contraindication to unsupervised community exercise or another medical condition judged by the study clinician to make participation unsafe.\n* Unable to walk to the community site even with a cane or walker, or dependent on a wheelchair for attendance.\n* A severe musculoskeletal, neurological, visual, hearing, cognitive, psychiatric, or communication impairment that prevents safe participation or valid completion of study procedures.\n* Unable to recognize Arabic numerals or unable to complete touchscreen selection with either upper limb.\n* Current participation in another structured physical, cognitive, or nutrition intervention study that may contaminate the assigned intervention.\n* Any other reason documented by the study clinician as making the individual unsuitable for participation.","ALL","60 Years",{"count":20,"type":21},365,"ESTIMATED","INTERVENTIONAL",[24],"NA","CEEEC-II is a 12-week, community-based, prospective extension study conducted in 32 community health service stations in Kunshan, China. It will invite older stroke survivors with hypertension and\u002For type 2 diabetes who participated in the preceding CEEEC Phase I trial (NCT06975501) to provide new informed consent and complete Phase II eligibility and baseline assessments. Participants will remain in the physical enrichment, cognitive enrichment, combined enrichment, or usual-care arm assigned to their community cluster in Phase I; no new randomization will occur in CEEEC-II. The upgraded program includes eight physician-led Vitality Camp sessions and four volunteer-led reinforcement activities. The physical component integrates aerobic, resistance, balance, flexibility, Baduanjin, and nutrition education. The cognitive component integrates health education with age-adapted games delivered through an AI-enabled interactive large screen. The primary objective is to evaluate the marginal effect of the cognitive enrichment factor on intrinsic capacity at 12 weeks.",[27,28,29,30],"Stroke","Hypertension","Type 2 Diabetes Mellitus (T2DM)","Multimorbidity",[32,33,34,35,36,37,38,39],"Intrinsic Capacity","Older Adults","Community Health Services","Environmental Enrichment","Cognitive Training","Physical Exercise","Multicomponent Intervention","Cluster-Assigned Extension Study","NOT_YET_RECRUITING","2026-08-18",{"date":43,"type":44},"2026-08-21","ACTUAL",{"date":46,"type":21},"2026-08-31",{"date":48,"type":21},"2027-01-03",{"name":50,"class":51},"Duke Kunshan University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":52},"100635404","phase-4-comparing-acupuncture-with-medication-to-reduce-depression-anxiety-and-comorbid-sleep-disorders-in-china-100635404","NCT07552246","Comparing Acupuncture With Medication to Reduce Depression, Anxiety and Comorbid Sleep Disorders in China","Comparing Acupuncture With Medication to Reduce Depression, Anxiety and Comorbid Sleep Disorders in China: A Preference-based Trial Comparing Clinical Efficacy, Cost-effectiveness and Environmental Footprint","Inclusion Criteria:\n\n1. Chinese nationals 18-65 years old\n2. At least one of the screening scores below suggestive of depression\u002Fanxiety tendencies:\n\n   1. Depressive state: Depression Self-Rating Scale (SDS) raw score ≥43; standard score ≥53 (27)\n   2. Anxiety state: Anxiety Self-Rating Scale (SAS) raw score ≥40; standard score ≥50 (28) Note: (standard score = raw score X 1.25)\n\nExclusion Criteria:\n\n1. Patients with severe comorbid physical illnesses that prevent them from completing the full course of treatment;\n2. Patients with a risk of suicide;\n3. Patients with a history of head trauma, loss of consciousness, or severe mental disorders;\n4. Patients with drugs or alcohol abuse;\n5. Patients who have received physical treatment methods within the past 3 months;\n6. Patients who have received antidepressant or antipsychotic medication treatment within the past 3 months;\n7. Patients with severe skin lesions or skin diseases.","18 Years","65 Years",{"count":63,"type":21},180,[65],"PHASE4","The main objective of this study is to compare medication (usual care; active comparator) with acupuncture (as experimental intervention) to identify the most (cost)effective and environmentally sustainable intervention to reduce depression, anxiety and comorbid sleep disorders in adults (18-65) in China.",[68,69],"Anxiety Depression","Sleep",[71,72,73,74,75],"Depression","Acupuncture","Antidepressants","anxiety","sleep","RECRUITING","2026-07-28",{"date":79,"type":44},"2026-07-29",{"date":81,"type":44},"2026-04-01",{"date":83,"type":21},"2027-12-31",{"name":50,"class":51},{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":17,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":4,"studyType":22,"phases":97,"briefSummary":98,"conditions":99,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":52},"100598795","community-and-primary-care-based-intervention-linked-with-mobile-technology-for-htn-control-in-nepal-100598795","NCT07076134","Community-and Primary Care-based Intervention Linked With mObile Technology for HTN Control in Nepal","A Pilot Trial of a Community-and Primary Care-based Intervention Linked With mObile Technology for Hypertension Control in Nepal (CoPILOT Trial)","CoPILOT","Inclusion Criteria:\n\n* Hypertensive patient's should be in the range of 30 to 70 years old living in selected communities with HTN (systolic BP ≥ 130 mmHg or diastolic ≥ 85 mmHg or taking antihypertensive medication)\n* They should have been diagnosed previously and under medication.\n* They should agree to the informed consent\n* FCHVs should be working for the selected communities and agree to the informed consent\n* FLHWs should work for the health facilities in selected communities and agree to the informed consent.\n\nExclusion Criteria:\n\n* Participants who are not able to respond during the data collection period.\n* Participants who are out of municipality during the data collection period.","30 Years","70 Years",{"count":96,"type":21},520,[24],"The clinical trial aims to evaluate whether a community and primary care-based intervention linked with mobile technology (CoPILOT) is acceptable, effective, cost-effective, sustainable, and scalable in improving hypertension (HTN) control among individuals aged 30 to 70 in Nepal. The primary research questions include:\n\nIs the use of the application by Frontline Health Workers (FLHWs) and Female Community Health Volunteers (FCHVs) feasible and acceptable? Can FCHVs equipped with mHealth technology effectively increase the linkage of individuals with elevated blood pressure (BP) to health facilities? Does a mobile-based lifestyle intervention reduce or control BP? Can adherence to prescribed HTN treatments be improved among patients through this intervention?",[28],"2025-08-13",{"date":102,"type":44},"2025-08-17",{"date":104,"type":21},"2025-08-15",{"date":106,"type":21},"2025-12-31",{"name":50,"class":51},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":116,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":119,"briefSummary":120,"conditions":121,"keywords":122,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":52},"100596431","embedded-community-based-heart-age-risk-education-trial-in-cinese-primary-healthcare-100596431","NCT07045363","Embedded Community-based Heart-Age Risk Education Trial in Cinese Primary Healthcare","Effectiveness of an Embedded Community-based Heart-Age Risk Education Model (E-CHARM) in Improving Cardiovascular Risk Awareness and Health Behaviors Among Older Adults With Hypertension: a Randomized Controlled Trial","E-CHARM","Inclusion Criteria:\n\n* Adults aged ≥60 years\n* Diagnosed with hypertension\n* Completed their government-funded annual health check within the past 3 months\n* Scheduled for a routine follow-up consultation within the enrollment window -Able to provide informed consent-\n\nExclusion Criteria:\n\n* Diagnosed dementia or severe cognitive impairment\n* Terminal illness\n* Participation in another clinical intervention trial",true,{"count":118,"type":21},600,[24],"This study evaluates the effectiveness of a brief Heart Age-based risk education intervention embedded in routine primary care for older adults with hypertension in China. The intervention uses routine health check data to generate a personalized one-page Heart Age report, delivered by physicians during regular follow-up visits. The trial tests whether this approach improves risk awareness and self-management behavior without disrupting clinical workflow.",[28],[123,124],"Heart Age","Health education","2025-07-16",{"date":127,"type":44},"2025-07-20",{"date":129,"type":21},"2025-07-19",{"date":131,"type":21},"2026-07-20",{"name":50,"class":51},""]