[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fatih Sultan Mehmet Training and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":711},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,26,0,25,[9,41,58,92,121,149,182,228,254,289,313,339,373,397,422,449,471,497,518,550,575,609,636,660,685],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100652795","the-relationship-between-lipedema-and-osteoporosis-100652795",false,"NCT07779603","The Relationship Between Lipedema and Osteoporosis","The Relationship Between Lipedema and Osteoporosis: A Cross-Sectional Observational Study","Inclusion Criteria:\n\n* being literate\n* voluntarily agreeing to participate in the study\n* being a postmenopausal woman\n* having a diagnosis of lipedema\n\nExclusion Criteria:\n\n* the presence of other types of edema in which a component other than lipedema predominates (e.g., lymphedema, venous edema, edema associated with heart or kidney failure, etc.)\n* chronic liver disease,\n* body mass index (BMI) of over 50.0 (this condition reflects severe obesity, which has a significant impact on health beyond lipedema alone)\n* the presence of rheumatological diseases that may lead to secondary osteoporosis\n* a history of cancer, endocrine disorders, neurological disorders, certain gastrointestinal disorders\n* use of medications related to osteoporosis\n* being under 18 years of age",true,"ALL","18 Years",{"count":21,"type":22},120,"ESTIMATED","1 Day","OBSERVATIONAL","The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.",[27,28],"Lipedema","Osteoporosis","NOT_YET_RECRUITING","2026-08-18",{"date":32,"type":33},"2026-08-21","ACTUAL",{"date":35,"type":22},"2026-08-20",{"date":37,"type":22},"2026-09-16",{"name":39,"class":40},"Fatih Sultan Mehmet Training and Research Hospital","OTHER",{"id":42,"slug":43,"hasResults":12,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":48,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":53,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":57,"locationsCount":4},"100652767","serum-magnesium-levels-in-patients-diagnosed-with-lipedema-100652767","NCT07779577","Serum Magnesium Levels in Patients Diagnosed With Lipedema","The Relationship Between Serum Magnesium Levels and Sleep Quality, Pain Levels, and Quality of Life in Patients Diagnosed With Lipedema: An Observational Cross-Sectional Study","Inclusion Criteria:\n\n* Serum magnesium levels must have been measured within the past 6 month\n* Be at least 18 years of age\n* Have a diagnosis of lipedema based on the Wold criteria\n* Have no cognitive or mental health issues\n* Agree to participate in the study\n\nExclusion Criteria:\n\n* No serum magnesium level measured within the past 6 months\n* Use of magnesium supplements for lipedema within the past 6 months, or the presence of any condition known to affect magnesium absorption or serum magnesium levels (e.g., use of a proton pump inhibitor \\[PPI\\] or diuretic)\n* The presence of other types of edema in which a component other than lipedema is predominant (e.g., lymphedema, venous edema, edema associated with heart or kidney failure, etc.)\n* A body mass index (BMI) of over 50.0 (this condition reflects severe obesity, which has a significant impact on health beyond lipedema alone)\n* Presence of a rheumatological disease, history of cancer, chronic liver disease, or endocrine disorder\n* Having been diagnosed with a psychiatric disorder, or use of psychiatric medications that may affect sleep\n* Being under 18 years of age",{"count":49,"type":22},128,"Female patients diagnosed with lipedema will be divided into two groups based on their Pittsburgh Sleep Quality Index (PSQI) scores: PSQI ≤ 5 and PSQI \\> 5. Age, body mass index (BMI), education level, menopausal status (reproductive period, perimenopausal period, postmenopausal period), number of births, duration of illness, occupation, marital status, disease stage, lipedema type, lower extremity functional scale, and the World Health Organization Quality of Life Scale - Short Form (Physical Health, Psychological Health, Social Relationships...)",[27,52],"Magnesium",{"date":32,"type":33},{"date":55,"type":22},"2026-08-16",{"date":37,"type":22},{"name":39,"class":40},{"id":59,"slug":60,"hasResults":12,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":4,"eligibilityCriteria":64,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":85,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},"100652700","individualized-vs-standard-peep-and-oxygen-reserve-index-in-laparoscopic-hernia-surgery-100652700","NCT07775573","Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery","The Effect of Individualized Positive End-Expiratory Pressure Application on Perioperative Oxygenation Assessed by Oxygen Reserve Index Compared to Standard PEEP in Patients Undergoing Laparoscopic Inguinal Hernia Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* Aged 18-75 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic unilateral inguinal hernia repair under general anesthesia\n* Body mass index (BMI) \\\u003C 35 kg\u002Fm²\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Age below 18 or above 75 years\n* ASA physical status IV-V\n* Emergency surgical procedure\n* Severe chronic or restrictive pulmonary disease\n* Pulmonary hypertension\n* Obstructive sleep apnea syndrome\n* Preoperative peripheral oxygen saturation \\\u003C 94% on room air\n* Respiratory tract infection within the last two weeks\n* Severe cardiac failure (NYHA III-IV)\n* Pregnancy\n* Communication difficulties preventing NRS assessment\n* Surgical complications during the procedure\n* Operation duration exceeding 3 hours\n* Refusal to provide informed consent","75 Years",{"count":67,"type":22},60,"During laparoscopic surgery under general anesthesia, lung function can be affected by increased abdominal pressure and patient positioning. Positive end-expiratory pressure (PEEP) is a ventilator setting that helps keep the lungs open during surgery. In standard practice, a fixed PEEP level is applied to all patients. An individualized PEEP approach tailors this setting to each patient based on lung recruitment maneuvers.\n\nThis study investigates whether individualized PEEP improves oxygenation compared to standard PEEP in patients undergoing laparoscopic inguinal hernia surgery. Oxygenation will be continuously monitored using the Oxygen Reserve Index (ORI), a non-invasive sensor. Lung aeration will also be assessed before and after surgery using bedside lung ultrasound.",[70,71,72,73],"Atelectasis","Perioperative Oxygenation","Laparoscopic Inguinal Hernia Repair","Mechanical Ventilation",[75,76,77,78,79,80,81,82,83,84],"Positive End-Expiratory Pressure","PEEP titration","Oxygen Reserve Index","ORI","Lung Ultrasound","Recruitment Maneuver","Lung Protective Ventilation","Dynamic Compliance","Pneumoperitoneum","Trendelenburg Position",{"date":35,"type":33},{"date":87,"type":22},"2026-09",{"date":89,"type":22},"2027-10",{"name":39,"class":40},1,{"id":93,"slug":94,"hasResults":12,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":65,"enrollmentInfo":99,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":101,"conditions":102,"keywords":105,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":118,"leadSponsor":120,"locationsCount":91},"100651907","lower-back-muscle-size-and-recovery-after-lumbar-disc-herniation-surgery-100651907","NCT07768241","Lower Back Muscle Size and Recovery After Lumbar Disc Herniation Surgery","Association of Preoperative Psoas Muscle Index and Multifidus Muscle Area With Postoperative Quality of Recovery Assessed Using the Quality of Recovery-15 (QoR-15) in Patients Undergoing Surgery for Lumbar Disc Herniation: A Prospective Observational Study","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* Scheduled for elective surgery for lumbar disc herniation\n* American Society of Anesthesiologists physical status I-III\n* Availability of a preoperative lumbar MRI obtained as part of routine clinical care\n* Scheduled to undergo surgery under general anesthesia\n* Sufficient cognitive and communication ability to understand and complete the quality of recovery (QoR-15) questionnaire\n* Willingness to participate and provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Revision lumbar spine surgery\n* Surgery for a spinal tumor, infection, trauma, vertebral fracture, spinal deformity, advanced spinal stenosis, or another condition other than lumbar disc herniation\n* Planned spinal fusion or instrumentation\n* History of a neuromuscular disorder\n* Severe cognitive impairment, inability to communicate, or inability to complete the QoR-15 questionnaire\n* Chronic opioid use or a history of opioid dependence\n* Preoperative lumbar MRI images of insufficient quality for psoas or multifidus muscle measurement",{"count":100,"type":22},100,"Recovery after surgery for a herniated disc in the lower back differs from person to person. The size of the muscles around the lower spine may be related to recovery, but this relationship is not well understood.\n\nThe purpose of this observational study is to determine whether the size of two lower-back muscles, the psoas and multifidus muscles, measured on magnetic resonance imaging (MRI) scans obtained before surgery is related to recovery after surgery. The study will include 100 adults aged 18 to 75 years who are scheduled for elective surgery for lumbar disc herniation.\n\nParticipants will receive their usual anesthesia, surgery, and postoperative care. The study will not require any additional imaging, blood tests, medicines, or procedures. Researchers will use each participant's existing preoperative lumbar MRI scan to measure the psoas and multifidus muscles. Participants will complete the 15-item Quality of Recovery questionnaire (QoR-15) before surgery and again 24 hours, 48 hours, and 7 days after surgery. Researchers will also collect information routinely recorded during care, including pain scores, pain medicine use, nausea and vomiting, time spent in the recovery unit, time to first walking, and length of hospital stay.\n\nThe primary objective is to determine whether preoperative psoas muscle index and multifidus muscle cross-sectional area are independently associated with postoperative Quality of Recovery-15 (QoR-15) scores 24 hours after lumbar disc herniation surgery.",[103,104],"Postoperative Recovery","Lumbar Disc Herniation",[106,107,108,109,110,111,112,113],"Psoas Muscle Index","Multifidus Muscle Area","Paraspinal Muscle Morphology","Quality of Recovery-15","Lumbar Magnetic Resonance Imaging","Lumbar Spine Surgery","Patient-Reported Outcome","Postoperative Pain","2026-08-13",{"date":116,"type":33},"2026-08-17",{"date":87,"type":22},{"date":119,"type":22},"2027-07",{"name":39,"class":40},{"id":122,"slug":123,"hasResults":12,"nctId":124,"briefTitle":125,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":12,"sex":18,"minAge":127,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":131,"conditions":132,"keywords":136,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":91},"100652066","investigation-of-the-relationship-between-shoulder-alpha-angle-and-humeral-head-displacement-percentage-measured-by-ultrasonography-in-neonatal-brachial-plexus-palsy-infants-with-clinical-parameters-100652066","NCT07768904","Investigation of the Relationship Between Shoulder Alpha Angle and Humeral Head Displacement Percentage Measured by Ultrasonography in Neonatal Brachial Plexus Palsy Infants With Clinical Parameters","Inclusion Criteria:\n\n* Diagnosis of neonatal brachial plexus injury (NBPI) between 3 months and 1 year of age\n* Narakas classification Group I, II, or III\n* Absence of nerve root avulsion\n\nExclusion Criteria:\n\n* Prior shoulder surgery for NBPI\n* Inability to tolerate ultrasonographic examination\n* Concomitant musculoskeletal (e.g., torticollis, humeral fracture) or neurological disease\n* Bilateral NBPI\n* Narakas classification Group IV\n* Botulinum toxin injection to the affected shoulder","3 Months","1 Year",{"count":130,"type":22},19,"This study will examine infants with a birth-related nerve injury called neonatal brachial plexus palsy, which can affect movement in the arm and sometimes cause the shoulder joint to shift out of its normal position (subluxation). Researchers will use ultrasound imaging to measure the shoulder joint and will compare these measurements with findings from a physical examination, to determine which clinical signs can help predict whether a baby's shoulder will develop this problem. The goal is to help doctors detect shoulder problems earlier, so that treatment can start sooner.",[133,134,135],"Glenohumeral Subluxation","Neonatal Brachial Plexus Palsy","Brachial Plexus Injuries",[137,138,139,140,141],"Alpha Angle","Shoulder Ultrasonography","Erb's Palsy","Glenohumeral Dysplasia","Humeral Head Displacement","2026-08-12",{"date":116,"type":33},{"date":145,"type":22},"2026-08",{"date":147,"type":22},"2027-11",{"name":39,"class":40},{"id":150,"slug":151,"hasResults":12,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":12,"sex":18,"minAge":156,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":158,"conditions":159,"keywords":164,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":179,"leadSponsor":181,"locationsCount":91},"100650733","gnri-and-rectus-femoris-muscle-thickness-in-older-patients-undergoing-hip-fracture-surgery-100650733","NCT07751692","GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery","Prognostic Value of the Geriatric Nutritional Risk Index and Ultrasonographic Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* Age 65 years or older\n* Scheduled to undergo surgical treatment for hip fracture\n* Provision of informed consent by the participant or, when applicable, a legally authorized representative\n\nExclusion Criteria:\n\n* Pathological fracture or fracture related to malignancy\n* Advanced neuromuscular disease\n* Active infection\n* Planned revision surgery\n* Lower limb amputation or severe deformity preventing rectus femoris muscle thickness measurement\n* Inability to obtain informed consent from the participant or a legally authorized representative","65 Years",{"count":21,"type":22},"This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.\n\nNutritional risk will be assessed using the Geriatric Nutritional Risk Index (GNRI), which is calculated from routine preoperative serum albumin, body weight, and ideal body weight. Rectus femoris muscle thickness will be measured before surgery using a brief, noninvasive ultrasound examination of the non-fractured thigh.\n\nParticipants will receive routine clinical care, and no treatment or anesthesia method will be assigned by the study. Clinical information will be collected from hospital records, including postoperative length of hospital stay, surgical site infection, and mortality. Survival status will be evaluated at 30 and 90 days after surgery using hospital records and\u002For telephone follow-up.",[160,161,162,163],"Hip Fracture","Malnutrition","Sarcopenia","Postoperative Complications",[165,166,167,168,169,170,171,172,173,174],"Geriatric Nutritional Risk Index","Rectus Femoris Muscle Thickness","Muscle Ultrasound","Geriatric Hip Fracture","Nutritional Risk","Postoperative Length of Stay","Surgical Site Infection","Prognostic Factors","30-Day Mortality","90-Day Mortality","2026-08-06",{"date":177,"type":33},"2026-08-07",{"date":145,"type":22},{"date":180,"type":22},"2027-06",{"name":39,"class":40},{"id":183,"slug":184,"hasResults":12,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":188,"eligibilityCriteria":189,"healthyVolunteers":12,"sex":190,"minAge":19,"maxAge":4,"enrollmentInfo":191,"targetDuration":4,"studyType":193,"phases":194,"briefSummary":196,"conditions":197,"keywords":203,"overallStatus":218,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":227},"100649200","deep-neuromuscular-blockade-and-a-low-residue-diet-for-the-surgical-field-in-vnotes-hysterectomy-100649200","NCT07730970","Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy","Effect of Deep Neuromuscular Blockade and a Preoperative Low-Residue Diet on Intra-operative Surgical Field Conditions During Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Hysterectomy: A 2×2 Factorial, Assessor-Blinded Randomized Controlled Trial","vNOTES_NMBDIET","Inclusion Criteria:\n\n* Adult women (aged 18 years or older) scheduled for hysterectomy for a benign (non-cancer) indication.\n* Judged suitable for the vNOTES approach by the operating surgeon.\n* Able to understand the study and provide written informed consent.\n\nExclusion Criteria:\n\n* Suspected or known gynaecological malignancy.\n* Conditions expected to make the approach or the field assessment non-standard (e.g., anticipated dense pelvic adhesions or severe endometriosis, a contraindication to vNOTES, or an obliterated cul-de-sac).\n* Any medical reason why deep neuromuscular blockade or sugammadex would be unsafe (defined with the anaesthesia team).\n* Any medical reason why a low-residue diet would be unsuitable.\n* Inability to give informed consent.","FEMALE",{"count":192,"type":22},160,"INTERVENTIONAL",[195],"NA","vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision. A clear surgical view is essential, and the main obstacle to the view is bowel falling into the pelvis. This randomized trial tests whether two simple measures improve the surgical field, individually or in combination: a preoperative low-residue diet for three days, and deeper intra-operative muscle relaxation (deep neuromuscular blockade). No group receives mechanical bowel preparation.\n\nUsing a 2×2 factorial design, participants are allocated equally (1:1:1:1) to one of four groups: (1) no diet with standard relaxation; (2) diet with standard relaxation; (3) no diet with deep relaxation; (4) diet with deep relaxation (the \"bundle\"). The surgical field is measured objectively: during a standardized window the carbon-dioxide insufflation pressure is lowered step by step, and 2-3 blinded assessors score the field from de-identified video. The primary outcome is the lowest pressure at which the field remains adequate; a lower pressure indicates an intrinsically better field.\n\nThe trial hypothesis is an interaction - that the combination achieves an adequate field at a meaningfully lower pressure than either measure alone. The final sample size is determined from an internal pilot. Secondary outcomes include the continuous field score, the need for an additional instrument to clear the field, postoperative nausea and vomiting, and routine operative outcomes.",[198,199,200,201,202],"Leiomyoma, Uterine","Benign Gynecological Disease","Abnormal Uterine Bleeding (AUB)","Uterine Prolapse","Adenomyosis of Uterus",[204,205,206,207,208,209,210,211,212,213,214,215,216,217],"vNOTES","vaginal natural orifice transluminal endoscopic surgery","deep neuromuscular blockade","rocuronium","post-tetanic count","low-residue diet","bowel preparation","insufflation pressure","pneumoperitoneum","surgical field","visualization","objective visualisation index (OVI)","factorial trial","assessor-blinded","RECRUITING","2026-07-29",{"date":221,"type":33},"2026-07-30",{"date":223,"type":33},"2026-07-01",{"date":225,"type":22},"2027-09-01",{"name":39,"class":40},3,{"id":229,"slug":230,"hasResults":12,"nctId":231,"briefTitle":232,"officialTitle":233,"acronym":4,"eligibilityCriteria":234,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":235,"targetDuration":4,"studyType":193,"phases":237,"briefSummary":238,"conditions":239,"keywords":242,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":247,"lastUpdatePostDateStruct":248,"startDateStruct":250,"completionDateStruct":251,"leadSponsor":253,"locationsCount":91},"100642008","remifentanil-vs-esmolol-during-intubation-for-cerebral-aneurysm-coil-embolization-100642008","NCT07660861","Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil Embolization","Effects of Remifentanil Versus Esmolol on Optic Nerve Sheath Diameter\u002FEyeball Transverse Diameter Ratio During Endotracheal Intubation in Patients Undergoing Cerebral Aneurysm Coil Embolization: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective cerebral aneurysm coil embolization under general anesthesia\n* Planned endotracheal intubation\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Emergency procedures\n* Hemodynamic instability before induction of anesthesia\n* Severe cardiac conduction abnormalities or clinically significant arrhythmias\n* Contraindication or allergy to remifentanil or esmolol\n* Chronic opioid use or opioid dependence\n* Known orbital disease, ocular trauma, or conditions interfering with optic nerve sheath diameter measurements\n* Anticipated difficult airway\n* Pregnancy\n* Refusal to participate in the study",{"count":236,"type":22},84,[195],"Endotracheal intubation may cause significant increases in blood pressure, heart rate, and intracranial pressure, particularly in patients undergoing cerebral aneurysm coil embolization. Remifentanil and esmolol are commonly used agents to attenuate these responses during anesthesia induction.\n\nThis randomized controlled trial aims to compare the effects of remifentanil and esmolol administered before endotracheal intubation on optic nerve sheath diameter\u002Feyeball transverse diameter ratio (ONSD\u002FETD), a noninvasive surrogate marker of intracranial pressure, as well as hemodynamic responses in patients undergoing elective cerebral aneurysm coil embolization.\n\nThe findings may help identify the most effective strategy for minimizing intubation-related intracranial pressure changes and hemodynamic fluctuations in neurointerventional anesthesia practice.",[240,241],"Cerebral Aneurysm Unruptured","Intracranial Pressure",[243,241,244,245,246],"Optic Nerve Sheath Diameter","Remifentanil","Esmolol","Coil Embolization","2026-06-16",{"date":249,"type":33},"2026-06-22",{"date":249,"type":22},{"date":252,"type":22},"2027-07-01",{"name":39,"class":40},{"id":255,"slug":256,"hasResults":12,"nctId":257,"briefTitle":258,"officialTitle":259,"acronym":4,"eligibilityCriteria":260,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":65,"enrollmentInfo":261,"targetDuration":4,"studyType":193,"phases":263,"briefSummary":264,"conditions":265,"keywords":269,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":91},"100636200","eyelid-taping-alone-versus-taping-with-lubricant-eye-drops-for-perioperative-corneal-protection-100636200","NCT07562594","Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection","Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection During General Anesthesia: A Randomized Assessor-Blinded Trial With Cost-Effectiveness Analysis","Inclusion Criteria:\n\n* Age 18 to 75 years\n* ASA physical status I or II\n* Scheduled for elective non-ocular surgery under general anesthesia\n* Expected anesthesia duration between 30 and 180 minutes\n* Supine surgical position\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Preoperative corneal epithelial defect, keratitis, conjunctivitis, conjunctival hyperemia, or chemosis\n* Known ocular surface disease (dry eye syndrome, Sjögren syndrome, rheumatoid arthritis, systemic lupus erythematosus, or other systemic conditions associated with ocular surface involvement)\n* Use of topical or systemic medications known to affect tear production within the past 30 days\n* History of ocular surgery or ocular trauma\n* Contact lens use\n* Planned head and neck surgery\n* Prone or lateral decubitus surgical position\n* Patients requiring rapid sequence induction\n* Inability or refusal to provide written informed consent",{"count":262,"type":22},200,[195],"During general anesthesia, the eye's natural protective reflexes are suppressed, which can lead to corneal drying and injury. To prevent this, anesthesiologists routinely tape the eyelids closed. In many centers, lubricant eye drops are also applied in addition to taping, but whether this adds meaningful protection is unclear.This study will compare two approaches to eye protection during general anesthesia lasting 30 minutes to 3 hours: eyelid taping alone versus eyelid taping combined with lubricant eye drops. Two hundred adult patients undergoing elective, non-eye surgery in the supine position will be randomly assigned to one of the two groups.The main outcome is corneal surface damage measured by a standardized fluorescein staining score (NEI scale, 0-15) assessed by a blinded evaluator one hour after surgery. Secondary outcomes include tear film stability (TBUT), tear production (Schirmer test), patient-reported eye symptoms at 2 and 24 hours after surgery, and a cost-effectiveness analysis comparing the two approaches.If taping alone proves equally effective, routine use of lubricant eye drops may be unnecessary, reducing costs without compromising patient safety.",[266,267,268],"Corneal Injury","Exposure Keratopathy","Perioperative Complications",[270,271,272,273,274,275,276,277,278,279,280],"Corneal protection","General anesthesia","Eyelid taping","Lubricant eye drops","Corneal fluorescein staining","NEI corneal staining scale","Perioperative eye care","Schirmer test","Tear break-up time","Cost-effectiveness","Randomized controlled trial","2026-05-04",{"date":283,"type":33},"2026-05-07",{"date":285,"type":22},"2026-06-01",{"date":287,"type":22},"2026-12-02",{"name":39,"class":40},{"id":290,"slug":291,"hasResults":12,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":295,"eligibilityCriteria":296,"healthyVolunteers":12,"sex":18,"minAge":297,"maxAge":298,"enrollmentInfo":299,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":301,"conditions":302,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":305,"lastUpdatePostDateStruct":306,"startDateStruct":308,"completionDateStruct":310,"leadSponsor":312,"locationsCount":91},"100630389","the-efficacy-and-safety-of-a-single-dose-hyaluronic-acid-injection-in-the-treatment-of-knee-osteoarthritis-100630389","NCT07487038","The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis","Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in Adults With Symptomatic Knee Osteoarthritis: A Retrospective Study","ESSDHAITKO","Inclusion Criteria:\n\n* Participants who have provided written informed consent.\n* Male and female participants aged 40 to 70.\n* Bilateral or unilateral, painful, primary knee osteoarthritis.\n* Knee pain lasting at least 4 weeks while standing, walking, and\u002For moving, and the presence of at least one of the following features on an X-ray taken within the last 3 months: tibiofemoral osteophytes, femoral or tibial endplate osteosclerosis, or narrowing of the joint space (Kellgren-Lawrence grade 2-3).\n* Baseline Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Score (sum of five 100-mm components) between 200 and 400 mm.\n* Individuals deemed by the investigator to be able to adhere to the visit schedule.\n* Discontinuation of all NSAIDs, corticosteroids, and other pain relievers, including over-the-counter medications, herbal treatments, or chondroprotective agents prior to injection, and no use of these during the study follow-up period (except for acetaminophen).\n* Patients who have not received another intra-articular injection in the knee or participated in a physical therapy program during the follow-up period.\n\nExclusion Criteria:\n\n* Participants hospitalized in the hospital.\n* Participants with inflammatory knee conditions other than OA (e.g., rheumatoid arthritis, chronic hemochromatosis, sickle cell anemia, and\u002For chondrocalcinosis, as well as arthropathies associated with systemic diseases such as gout and hemophilia, and infectious joint disease).\n\nThe presence of significant joint effusion identified by the investigator during a clinical examination and confirmed by an ultrasound examination performed on each patient to determine the presence of effusion\n\n* Body mass index (BMI) \\>35 kg\u002Fm²\n* Severe misalignment of the knee axis (i.e., \\>12° severe varus or valgus deformity and\u002For clinically significant moderate to severe instability).\n* Clinical findings of hip osteoarthritis (OA) and\u002For hip joint replacement on the same side as the affected knee. Hip joint replacement on the opposite side of the affected knee is not exclusionary, provided the patient does not have symptomatic hip OA.\n* Surgical intervention on the symptomatic knee within the previous 12 months (including joint replacement) or arthroscopy of the symptomatic knee within the past 3 months (note: joint replacement of the contralateral knee is permitted if performed more than 12 months prior and the participant does not report pain of ≥ 20 mm on the WOMAC pain subscale).\n* Intra-articular (IA) injections in both knees within the past 4 weeks (e.g., corticosteroids, chondroprotective agents).\n* Changes to current medications or the addition of new medications to treat knee OA within the past 4 weeks (i.e., a change in dose or regimen lasting at least 4 weeks).\n* Regular use of opioid pain relievers for pain management. Use of long-acting pain relievers such as analgesic patches, methadone, and levorphanol at any time","40 Years","70 Years",{"count":300,"type":22},133,"HA therapy typically consists of several intra-articular injections administered at weekly intervals. A single-dose IA-HA treatment offers patients and physicians a treatment option that involves both lower costs and fewer clinic visits. Furthermore, considering the administration procedure, we believe that single-dose therapy helps reduce the risk of potential side effects.\n\nIn light of this information, our study aims to retrospectively evaluate the efficacy and safety of HA in patients with symptomatic knee OA who have received a single-dose intra-articular HA injection.",[303,304],"Knee Osteoarthristis","Hyaluronic Acid","2026-04-24",{"date":307,"type":33},"2026-04-29",{"date":309,"type":22},"2026-05-01",{"date":311,"type":22},"2026-05-15",{"name":39,"class":40},{"id":314,"slug":315,"hasResults":12,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":4,"eligibilityCriteria":319,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":320,"targetDuration":128,"studyType":24,"phases":4,"briefSummary":321,"conditions":322,"keywords":324,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":334,"completionDateStruct":336,"leadSponsor":338,"locationsCount":91},"100634897","effects-of-ultrasound-guided-scalp-block-on-opioid-use-hemodynamics-and-postoperative-inflammation-in-craniotomy-100634897","NCT07545655","Effects of Ultrasound-Guided Scalp Block on Opioid Use, Hemodynamics, and Postoperative Inflammation in Craniotomy","Investigation of the Effects of Preoperative Ultrasound-Guided Scalp Block on Perioperative Opioid Consumption, Hemodynamic Stability, and Inflammatory Response in Patients Undergoing Craniotomy With a Skull Pin Head Holder","Inclusion Criteria:\n\n* Aged 18 years and older\n* Scheduled for elective intracranial surgery with skull pin head holder fixation\n* Classified as American Society of Anesthesiologists (ASA) physical status I-III\n* Provided written informed consent in the preoperative period\n\nExclusion Criteria:\n\n* Allergy to local anesthetics\n* Coagulopathy or anticoagulant use\n* Local infection at injection site\n* Pregnancy or breastfeeding\n* Chronic opioid use (\\>3 months) or chronic pain syndrome\n* Severe psychiatric disorders affecting pain assessment\n* Emergency surgery\n* Active infection or rheumatic disease\n* Hematological disease or malignancy (active or within 5 years)\n* Recent use of biological agents, chemotherapy, or corticosteroids (within 30 days)\n* NSAID use within 24 hours before surgery\n* Advanced organ failure (NYHA III-IV, Child-Pugh C, eGFR \\\u003C30 mL\u002Fmin)\n* Refusal to participate\n* Communication difficulties preventing pain assessment",{"count":67,"type":22},"This study shows that in craniotomy patients using a skull pin head holder, an ultrasound-guided scalp block reduces perioperative opioid consumption, improves hemodynamic stability, and decreases the inflammatory response.",[323],"Craniotomy Surgery",[325,326,327,328,329,330],"Craniotomy","Ultrasound-guided scalp block","Skull pin head holder","Perioperative opioid consumption","Hemodynamic stability","Inflammatory response","2026-04-21",{"date":333,"type":33},"2026-04-22",{"date":335,"type":22},"2026-04-10",{"date":337,"type":22},"2027-03-10",{"name":39,"class":40},{"id":340,"slug":341,"hasResults":12,"nctId":342,"briefTitle":343,"officialTitle":344,"acronym":4,"eligibilityCriteria":345,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":156,"enrollmentInfo":346,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":348,"conditions":349,"keywords":354,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":366,"lastUpdatePostDateStruct":367,"startDateStruct":369,"completionDateStruct":370,"leadSponsor":372,"locationsCount":91},"100633591","ultrasound-vs-clinical-parameters-for-difficult-airway-prediction-in-obesity-100633591","NCT07528677","Ultrasound vs Clinical Parameters for Difficult Airway Prediction in Obesity","Comparison of Airway Ultrasonography and Conventional Difficult Airway Parameters for Predicting Difficult Airway in Obese Patients: A Prospective Observational Study","Inclusion Criteria:\n\n* Age 18-65 years\n* BMI \\>30 kg\u002Fm2\n* ASA physical status I, II, or III\n* Scheduled for elective surgery requiring orotracheal intubation under general anesthesia\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Emergency surgery\n* History of previous head and neck surgery or radiotherapy\n* Known or anticipated difficult airway (history of difficult intubation)\n* Presence of cervical spine pathology or limited neck mobility\n* Presence of oropharyngeal or laryngeal pathology\n* Pregnancy\n* Patients with tracheostomy\n* Refusal to participate",{"count":347,"type":22},70,"Obesity is associated with anatomical changes in the upper airway that increase the risk of difficult laryngoscopy and difficult mask ventilation during anesthesia. Conventional airway assessment parameters such as Mallampati score, neck circumference, and STOP-BANG scale are widely used but have limited predictive accuracy in obese patients. Airway ultrasonography has emerged as a promising non-invasive tool for difficult airway prediction; however, ultrasonographic criteria have not yet been standardized.\n\nThis prospective observational study aims to evaluate the utility of airway ultrasonography in predicting difficult airway in adult obese patients (BMI \\>30 kg\u002Fm²) scheduled for elective surgery under general anesthesia. Ultrasonographic measurements will include the distance from skin to hyoid bone (DSHB) at the level of the hyoid bone, the anterior neck soft tissue thickness at the thyrohyoid membrane level, and the hyomental distance ratio (HMDR). These parameters will be compared with conventional airway assessment tools and correlated with intraoperative Cormack-Lehane laryngoscopy grade and Han Scale mask ventilation score to determine their predictive value for difficult airway.",[350,351,352,353],"Obesity (BMI > 35)","Difficult Airway","Difficult Airway Intubation","Difficult Mask Ventilation",[355,356,357,358,359,360,361,362,363,364,271,365],"Airway ultrasonography","Difficult airway prediction","Obese patients","Cormack-Lehane classification","Han Scale","Hyomental distance ratio","Distance from skin to hyoid bone","Neck circumference","Mallampati score","STOP-BANG scale","Orotracheal intubation","2026-04-09",{"date":368,"type":33},"2026-04-14",{"date":335,"type":22},{"date":371,"type":22},"2026-11",{"name":39,"class":40},{"id":374,"slug":375,"hasResults":12,"nctId":376,"briefTitle":377,"officialTitle":378,"acronym":4,"eligibilityCriteria":379,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":380,"targetDuration":128,"studyType":24,"phases":4,"briefSummary":381,"conditions":382,"keywords":384,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":389,"lastUpdatePostDateStruct":390,"startDateStruct":392,"completionDateStruct":394,"leadSponsor":396,"locationsCount":91},"100633218","laryngeal-edema-assessment-by-cuff-leak-test-and-ultrasound-in-icu-patients-and-its-relationship-with-weaning-success-100633218","NCT07523828","Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success","The Relationship Between Assessment of Laryngeal Edema in Intensive Care Patients Using Cuff Leak Test and Ultrasound-Guided Laryngeal Air Column Width Difference and Weaning Success","Inclusion Criteria:\n\n* Patients who have been intubated and receiving invasive mechanical ventilation for at least 24 hours in the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital and who are considered by the intensive care physician to be ready for weaning from mechanical ventilation:\n* Patients over 18 years of age\n* Patients who have given their voluntary consent\n\nExclusion Criteria:\n\n* Patients under 18 years of age\n* Patients with a history of oral cavity surgery such as direct laryngoscopy and biopsy, microlaryngoscopic surgery, tonsillectomy, adenoidectomy, soft palate, oropharynx, hypopharynx, larynx and trachea,\n* Patients with a history of allergy, asthma, reflux, upper respiratory tract viral or fungal infections, and cancer surgery,\n* Patients who received radiotherapy to the neck region, or who had more than one intubation attempt in the previous year,\n* Tracheostomized patients, patients with upper respiratory tract obstruction, vocal cord paralysis, and patients with stridor clinical picture before intubation,\n* Patients for whom voluntary consent cannot be obtained",{"count":100,"type":22},"This study evaluates laryngeal edema in ICU patients during weaning from mechanical ventilation. It compares the cuff leak test and ultrasound-based laryngeal air column measurements in predicting weaning success. Ultrasound offers a non-invasive and real-time alternative for airway assessment. The study also examines post-extubation complications such as stridor, sore throat, dysphonia, and dysphagia.",[383],"Laryngeal Edema",[385,386,387,388],"laryngeal edema","airway ultrasound","cuff leak test","weaning success","2026-04-05",{"date":391,"type":33},"2026-04-13",{"date":393,"type":22},"2026-04-08",{"date":395,"type":22},"2026-08-30",{"name":39,"class":40},{"id":398,"slug":399,"hasResults":12,"nctId":400,"briefTitle":401,"officialTitle":402,"acronym":403,"eligibilityCriteria":404,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":405,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":406,"conditions":407,"keywords":410,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":91},"100630268","lymphoedema-diagnosis-and-treatment-100630268","NCT07485465","Lymphoedema Diagnosis and Treatment","The Role of Chat GPT in the Diagnosis and Treatment of Lymphedema","CDTL","Inclusion Criteria:\n\n* Patients over the age of 18\n* Clinical diagnosis of lymphoedema\n* Clinical diagnosis of lipoedema\n* Clinical diagnosis of venous insufficiency\n\nExclusion Criteria:\n\n* Lack of medical history\n* Lack of demographic data\n* Lack of clinical data and\n* Lack of imaging methods",{"count":7,"type":22},"A domain-specific, custom-trained large language model for the differential diagnosis and treatment planning of lymphedema, lipedema, and venous insufficiency.",[408,409],"Lymphedema","Artificial Intelligence (AI)",[411,412,413],"lymphedema","chat gpt","artificial intelligence","2026-03-17",{"date":416,"type":33},"2026-03-20",{"date":418,"type":22},"2026-03-15",{"date":420,"type":22},"2026-04-01",{"name":39,"class":40},{"id":423,"slug":424,"hasResults":12,"nctId":425,"briefTitle":426,"officialTitle":427,"acronym":428,"eligibilityCriteria":429,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":156,"enrollmentInfo":430,"targetDuration":4,"studyType":193,"phases":432,"briefSummary":433,"conditions":434,"keywords":437,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":441,"lastUpdatePostDateStruct":442,"startDateStruct":444,"completionDateStruct":446,"leadSponsor":448,"locationsCount":91},"100627158","effect-of-magnetotherapy-combined-with-cold-application-and-exercise-in-patients-with-lateral-epicondylitis-100627158","NCT07444996","Effect of Magnetotherapy Combined With Cold Application and Exercise in Patients With Lateral Epicondylitis","Effectiveness of Magnetotherapy in Patients With Lateral Epicondylitis: A Randomized Double-Blind Controlled Trial","MAGNET-LE","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Clinical diagnosis of lateral epicondylitis\n* Tenderness over the lateral epicondyle on palpation\n* Tenderness over the common extensor tendon\n* At least one positive provocation test (Cozen, Mill's, or Maudsley's test)\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Acute infection\n* Elbow surgery within the past 12 months\n* Presence of electronic implants (e.g., pacemaker, cochlear implant)\n* Pregnancy\n* Physical therapy for the elbow within the past 3 months\n* Corticosteroid injection to the elbow within the past 3 months\n* History of elbow trauma within the past 3 months\n* Hyperthyroidism or adrenal hyperfunction\n* Paroxysmal neurological disorders (e.g., epilepsy)\n* Myasthenia gravis\n* Inability to comply with the treatment protocol or follow-up assessments",{"count":431,"type":22},40,[195],"This study aims to evaluate the effectiveness of magnetotherapy in the treatment of lateral epicondylitis (tennis elbow). Lateral epicondylitis is a common musculoskeletal condition characterized by pain and tenderness over the outer part of the elbow, often associated with repetitive wrist extension and gripping activities. It may cause reduced grip strength, functional limitations, and decreased quality of life.\n\nIn this prospective, randomized, double-blind, sham-controlled clinical trial, 40 patients aged 18-65 years diagnosed with lateral epicondylitis will be enrolled. Participants will be randomly assigned into two groups using the sealed envelope method.\n\nThe experimental group will receive active magnetotherapy in addition to standard treatment (local application and supervised exercise therapy). The control group will receive sham magnetotherapy (inactive device without magnetic field) plus the same standard treatment. Treatments will be administered five days per week for three weeks.\n\nMagnetotherapy will be applied at a frequency of 50 Hz and intensity of 85 Gauss for 30 minutes per session. All participants will also receive 15 minutes of local application and 15 minutes of supervised exercises including eccentric wrist extensor exercises, isotonic strengthening, stretching, and isometric exercises.\n\nOutcomes will be evaluated at baseline (week 0), at the end of treatment (week 3), and at follow-up (week 12). Primary and secondary outcome measures include pain intensity (Visual Analog Scale), pressure pain threshold (algometer), grip strength (hand dynamometer), functional status (PRTEE and QuickDASH questionnaires), quality of life (SF-36), clinical provocation tests (Cozen, Mill's, and Maudsley's tests), and patient satisfaction (Likert scale).\n\nThe study hypothesis is that adding magnetotherapy to standard treatment will provide additional benefit in reducing pain and improving function compared to standard treatment alone.",[435,436],"Magnetotherapy","Lateral Epicondylitis (Tennis Elbow)",[438,439,440],"magnetotherapy","lateral epicondylitis","tennis elbow","2026-03-05",{"date":443,"type":33},"2026-03-09",{"date":445,"type":22},"2026-02-27",{"date":447,"type":22},"2026-11-27",{"name":39,"class":40},{"id":450,"slug":451,"hasResults":12,"nctId":452,"briefTitle":453,"officialTitle":454,"acronym":4,"eligibilityCriteria":455,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":456,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":457,"conditions":458,"keywords":460,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":465,"lastUpdatePostDateStruct":466,"startDateStruct":467,"completionDateStruct":469,"leadSponsor":470,"locationsCount":4},"100627691","prediction-of-postoperative-pain-using-venous-cannulation-pain-and-preoperative-anxiety-scores-100627691","NCT07451925","Prediction of Postoperative Pain Using Venous Cannulation Pain and Preoperative Anxiety Scores","Association of Venous Cannulation Pain and Preoperative Anxiety (APAIS) With Postoperative Pain Following Elective Laparoscopic Cholecystectomy: A Prospective Observational Study","Inclusion Criteria:\n\n* Age ≥18 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia\n* Ability to understand and use the Visual Analog Scale (VAS)\n* Ability to complete the Amsterdam Preoperative Anxiety and Information Scale (APAIS)\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Conversion from laparoscopic to open surgery\n* Cognitive impairment or inability to communicate effectively\n* Chronic pain lasting longer than 3 months\n* More than three venous cannulation attempts\n* Surgical duration exceeding 2 hours\n* Refusal to participate",{"count":100,"type":22},"Postoperative pain remains a significant clinical problem affecting recovery, mobilization, and patient satisfaction after surgery. Considerable interindividual variability exists in postoperative pain intensity even among patients undergoing the same surgical procedure. This variability may be influenced not only by the extent of surgical trauma but also by individual pain sensitivity and psychological factors such as preoperative anxiety.\n\nThe aim of this prospective observational study is to evaluate whether pain intensity reported during routine venous cannulation and preoperative anxiety levels assessed by the Amsterdam Preoperative Anxiety and Information Scale (APAIS) can predict early postoperative pain severity in patients undergoing elective laparoscopic cholecystectomy under general anesthesia. Venous cannulation pain will be assessed using a 0-10 visual analog scale (VAS), and anxiety levels will be measured preoperatively using APAIS. Postoperative pain will be evaluated at predefined time points within the first 12 hours after surgery using VAS scores and analgesic consumption. Identifying simple and easily obtainable preoperative predictors may allow individualized postoperative analgesic strategies for patients at higher risk of severe postoperative pain.",[459,113],"Preoperative Anxiety",[461,462,463,464],"APAIS","postoperative pain","preoperative anxiety","Laparoscopic Cholecystectomy","2026-03-04",{"date":441,"type":33},{"date":468,"type":22},"2026-03-02",{"date":223,"type":22},{"name":39,"class":40},{"id":472,"slug":473,"hasResults":12,"nctId":474,"briefTitle":475,"officialTitle":476,"acronym":4,"eligibilityCriteria":477,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":478,"enrollmentInfo":479,"targetDuration":4,"studyType":193,"phases":481,"briefSummary":482,"conditions":483,"keywords":486,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":490,"lastUpdatePostDateStruct":491,"startDateStruct":492,"completionDateStruct":494,"leadSponsor":496,"locationsCount":91},"100625857","effect-of-kinesio-taping-combined-with-schroth-therapy-in-young-adults-with-idiopathic-scoliosis-100625857","NCT07428083","Effect of Kinesio Taping Combined With Schroth Therapy in Young Adults With Idiopathic Scoliosis","Comparison of Schroth Therapy and Kinesiotaping in Lower Back and Back Pain in Young Adults With Idiopathic Scoliosis: A Double-Blind Placebo-Controlled Randomized Study","Inclusion Criteria:\n\n* Individuals aged between 18 and 30 years.\n* Radiologically confirmed diagnosis of idiopathic scoliosis.\n* Cobb angle between 10° and 30° and considered candidates for conservative treatment.\n* Risser stage 5.\n* History of low back or back pain within the last 3 months (defined as NRS ≥ 4).\n* No acute orthopedic or neurological condition that would prevent participation in physical exercise interventions.\n* Willingness to participate voluntarily and provide written informed consent.\n* Ability to attend treatment sessions regularly throughout the study period.\n\nExclusion Criteria:\n\n* Diagnosis of non-structural (functional) scoliosis, congenital scoliosis, or neuromuscular scoliosis.\n* History of previous spinal surgery.\n* Participation in scoliosis-specific exercise therapy within the last 6 months.\n* Presence of open wounds, dermatological conditions, or allergy to taping materials.\n* History of psychiatric disorders or neurological diseases.","30 Years",{"count":480,"type":22},51,[195],"In this study, the effects of Kinesio Taping methods applied in combination with Schroth therapy on pain and functional capacity in young adults diagnosed with idiopathic scoliosis will be evaluated.\n\nThis study is designed as a randomized controlled trial. Participants will be randomly assigned to one of three groups:\n\nGroup 1: Schroth therapy combined with Kinesio Taping\n\nGroup 2: Schroth therapy alone\n\nGroup 3: Schroth therapy combined with sham Kinesio Taping\n\nKinesio Taping will be applied for 4 weeks. The tape will remain in place for 5 consecutive days, followed by a 2-day rest period for the skin, and this cycle will be repeated throughout the intervention period.\n\nSchroth therapy will be administered 3 times per week for 4 weeks.\n\nAssessments will be conducted at baseline (Week 0), during treatment (Week 2), at the end of treatment (Week 4), and at follow-up (Week 8).\n\nThe primary outcome measures will be pain intensity assessed by the Numeric Rating Scale (NRS) and functional disability assessed by the Oswestry Disability Index (ODI). Secondary outcome measures will include the Scoliosis Research Society-22 (SRS-22) questionnaire and the Patient Global Impression of Change (PGIC) scale.",[484,485],"Scoliosis Idiopathic","Kinesio Taping",[487,488,489],"Scoliosis idiopathic","Kinesio taping","Schroth therapy","2026-02-26",{"date":468,"type":33},{"date":493,"type":22},"2026-02-01",{"date":495,"type":22},"2026-11-01",{"name":39,"class":40},{"id":498,"slug":499,"hasResults":12,"nctId":500,"briefTitle":501,"officialTitle":502,"acronym":4,"eligibilityCriteria":503,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":156,"enrollmentInfo":504,"targetDuration":4,"studyType":193,"phases":505,"briefSummary":506,"conditions":507,"keywords":510,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":513,"lastUpdatePostDateStruct":514,"startDateStruct":515,"completionDateStruct":516,"leadSponsor":517,"locationsCount":91},"100626463","magnetotherapy-in-carpal-tunnel-syndrome-randomized-controlled-study-100626463","NCT07435961","Magnetotherapy in Carpal Tunnel Syndrome: Randomized Controlled Study","Evaluation of the Effectiveness of Magnetotherapy in Patients With Carpal Tunnel Syndrome: A Placebo-Controlled, Triple-Arm, Randomized, Double-Blind Study","Inclusion Criteria:\n\n* Adults aged between 18 and 65 years.\n\nClinical diagnosis of carpal tunnel syndrome (CTS) based on physical examination findings, including positive Tinel and\u002For Phalen tests and hypoesthesia in the 3rd to 5th digits.\n\nElectrophysiologically confirmed mild-to-moderate carpal tunnel syndrome based on electromyography (EMG) findings.\n\nExclusion Criteria:\n\n* Severe carpal tunnel syndrome confirmed electrophysiologically by electromyography (EMG).\n\nHistory of previous surgical intervention for carpal tunnel syndrome.\n\nPresence of other peripheral nerve entrapments (e.g., ulnar nerve entrapment, radial nerve entrapment).\n\nElectrophysiologically confirmed polyneuropathy or cervical radiculopathy\u002Fcervical discopathy.\n\nRheumatologic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus).\n\nDiabetes mellitus (Type 1 or Type 2).\n\nPregnancy.\n\nPresence of electronic implants such as cardiac pacemaker, cochlear implant, or implantable defibrillator.\n\nActive acute infection.\n\nHistory of malignancy.\n\nReceipt of physical therapy or rehabilitation for the wrist or surrounding area within the past 6 months.\n\nCorticosteroid injection to the wrist within the past 6 months.\n\nHyperthyroidism or adrenal gland hyperfunction.\n\nOpen growth plates (epiphyseal plates not closed).\n\nParoxysmal neurological disorders (e.g., epilepsy).\n\nMyasthenia gravis.\n\nRegular use of pain medications such as pregabalin, duloxetine, or non-steroidal anti-inflammatory drugs (NSAIDs).",{"count":67,"type":22},[195],"This study is designed to investigate the effectiveness of low-frequency pulsed electromagnetic field therapy in individuals diagnosed with mild-to-moderate carpal tunnel syndrome (CTS). This double-blind, randomized controlled trial will randomly assign participants into three groups:\n\nGroup 1: Active magnetotherapy\n\nGroup 2: Placebo magnetotherapy (treatment using an identical device that does not generate a magnetic field)\n\nGroup 3: Routine (conservative) treatment group\n\nAll participants will receive a standard nighttime wrist splint and a standardized nerve and tendon gliding exercise protocol. Magnetic field applications will be administered five days per week for a total of 15 sessions. Assessments will be conducted at baseline (T0), at the end of treatment (T1 - Week 3), at 1 month (T2), and at 3 months (T3).\n\nThe primary outcome measures include the Boston Carpal Tunnel Questionnaire (BCTQ), pain intensity assessed by the Visual Analog Scale (VAS), functional status measured by QuickDASH, median nerve cross-sectional area assessed by ultrasonography, sensory function evaluated using the Semmes-Weinstein monofilament test, grip strength measured by dynamometry, and clinical test results (Tinel and Phalen tests). Secondary outcomes include sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI) and patient satisfaction.\n\nThis study aims to contribute to the scientific evidence regarding the effectiveness of magnetotherapy as a non-invasive treatment option for carpal tunnel syndrome.",[435,508,509],"Carpal Tunnel Syndrome (CTS)","Median Nerve Compression",[511,512,438],"median nerve compression","carpal tunnel syndrome(cts)","2026-02-21",{"date":445,"type":33},{"date":493,"type":22},{"date":495,"type":22},{"name":39,"class":40},{"id":519,"slug":520,"hasResults":12,"nctId":521,"briefTitle":522,"officialTitle":522,"acronym":4,"eligibilityCriteria":523,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":524,"enrollmentInfo":525,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":526,"conditions":527,"keywords":533,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":542,"lastUpdatePostDateStruct":543,"startDateStruct":545,"completionDateStruct":547,"leadSponsor":549,"locationsCount":91},"100625957","validity-and-reliability-of-the-hypertonia-assessment-tool-hat-in-stroke-patients-100625957","NCT07429383","Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke Patients","Inclusion Criteria:\n\n* Age 18 years and older\n* Clinically and radiologically confirmed diagnosis of stroke (ischemic or -hemorrhagic)\n* Brunnstrom stage between 2 and 6\n* Presence of post-stroke hypertonia (spasticity, dystonia, or rigidity)\n* Cognitive level sufficient to cooperate with assessments (Mini-Mental State Examination (MMSE) score \\>23 or equivalent clinical evaluation)\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Age under 18 years\n* Presence of severe accompanying neurodegenerative diseases (e.g., Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis)\n* Presence of primary musculoskeletal disorders affecting motor performance (e.g., rheumatologic diseases, fractures)\n* Brunnstrom stage of 1\n* Severe aphasia, impaired consciousness, or cognitive deficits preventing effective communication and cooperation\n* Any psychiatric disorder that may interfere with study participation","80 Years",{"count":67,"type":22},"In this study, the validity and reliability of the Hypertonia Assessment Tool (HAT), which has previously been validated in the pediatric cerebral palsy (CP) population, will be evaluated in adult individuals who have experienced a stroke. The HAT is a specific clinical instrument designed to differentiate subtypes of hypertonia, including spasticity, dystonia, and rigidity.\n\nAccurate classification of hypertonia subtypes following stroke is crucial for guiding rehabilitation strategies. However, the HAT has not yet been validated in the adult post-stroke population. This study will be conducted at the Physical Medicine and Rehabilitation Clinic of SBU Fatih Sultan Mehmet Training and Research Hospital. The study aims to evaluate the validity and reliability of the HAT for use in adults with stroke.",[528,529,530,531,532],"Stroke","Hypertonia","Dystonia","Rigidity","Hemiplegia",[534,535,536,537,538,539,540,541],"hypertonia","dystonia","rigidity","reliability","validity","hemiplegia","spasticity","stroke","2026-02-20",{"date":544,"type":33},"2026-02-24",{"date":546,"type":22},"2026-03-01",{"date":548,"type":22},"2026-10-01",{"name":39,"class":40},{"id":551,"slug":552,"hasResults":12,"nctId":553,"briefTitle":554,"officialTitle":555,"acronym":4,"eligibilityCriteria":556,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":156,"enrollmentInfo":557,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":558,"conditions":559,"keywords":561,"overallStatus":218,"whyStopped":4,"lastUpdateSubmitDate":567,"lastUpdatePostDateStruct":568,"startDateStruct":570,"completionDateStruct":572,"leadSponsor":574,"locationsCount":91},"100618065","effect-of-ultrasound-guided-quadro-iliac-plane-block-on-postoperative-analgesia-after-lumbar-spinal-surgery-100618065","NCT07326774","Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal Surgery","Evaluation of the Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia in Patients Undergoing Lumbar Spinal Surgery","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Body mass index (BMI) \\\u003C35 kg\u002Fm²\n* Scheduled for elective posterior lumbar spinal instrumentation surgery under general anesthesia\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Emergency surgery\n* Local infection or hematoma at the block application site\n* Previous surgery at the block application site\n* Presence of coagulopathy\n* Known allergy or toxicity to local anesthetics\n* History of hematological, renal, or hepatic disease, or advanced respiratory or cardiac failure\n* Chronic analgesic use, chronic alcohol consumption, or substance abuse\n* Inability to speak Turkish or presence of language\u002Fcommunication barriers",{"count":67,"type":22},"This prospective observational study aims to evaluate the effect of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia in patients undergoing lumbar spinal surgery. Lumbar spinal procedures are commonly associated with significant postoperative pain, which may impair early mobilization and increase opioid consumption. In routine clinical practice, QIPB is increasingly used as part of multimodal analgesia to improve pain control and reduce opioid-related adverse effects.\n\nAdult patients scheduled for elective lumbar spinal surgery under general anesthesia will be followed according to routine clinical care. Postoperative analgesia will be managed with intravenous patient-controlled analgesia (PCA) using tramadol, with or without the addition of ultrasound-guided QIPB, based on the preference of the attending anesthesiologist. No intervention or treatment assignment will be performed by the investigators.\n\nPostoperative pain scores at rest and during movement, opioid consumption, need for rescue analgesics, incidence of nausea and vomiting, and patient satisfaction will be recorded during the first 24 hours after surgery. The findings of this study are expected to provide further clinical evidence regarding the effectiveness of QIPB as part of multimodal analgesia in lumbar spinal surgery.",[113,111,560],"Postoperative Analgesia",[562,563,564,565,560,566],"Quadro-Iliac Plane Block","QIPB","Ultrasound-Guided Regional Anesthesia","Lumbar Spinal Surgery","Patient-Controlled Analgesia","2026-02-19",{"date":569,"type":33},"2026-02-23",{"date":571,"type":33},"2026-01-05",{"date":573,"type":22},"2026-10",{"name":39,"class":40},{"id":576,"slug":577,"hasResults":12,"nctId":578,"briefTitle":579,"officialTitle":580,"acronym":581,"eligibilityCriteria":582,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":156,"enrollmentInfo":583,"targetDuration":4,"studyType":193,"phases":585,"briefSummary":586,"conditions":587,"keywords":592,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":601,"lastUpdatePostDateStruct":602,"startDateStruct":604,"completionDateStruct":606,"leadSponsor":608,"locationsCount":91},"100624025","oxygen-reserve-index-guided-oxygen-titration-during-surgery-in-the-beach-chair-position-100624025","NCT07404267","Oxygen Reserve Index-Guided Oxygen Titration During Surgery in the Beach Chair Position","The Utility of Oxygen Reserve Index Guidance in Inspiratory Oxygen Titration for Patients Undergoing Surgery in the Beach Chair Position: A Prospective Comparative Study","ORI-BCP","Inclusion Criteria:\n\n* Adult patients aged 18 to 65 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective orthopedic surgery in the beach chair position\n* Body mass index (BMI) \\\u003C35 kg\u002Fm²\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 or ≥65 years\n* Finger deformities preventing the use of Oxygen Reserve Index (ORi) monitoring\n* Severe anemia (hemoglobin \\\u003C8 g\u002FdL)\n* Pregnancy\n* Refusal or inability to provide informed consent\n* History of stroke or significant vascular pathology\n* Severe cardiac or respiratory disease",{"count":584,"type":22},80,[195],"This study aims to evaluate whether guidance by the Oxygen Reserve Index (ORi) improves inspiratory oxygen fraction (FiO₂) titration compared with conventional pulse oximetry (SpO₂)-guided oxygen administration in adult patients undergoing surgery in the beach chair position.\n\nOxygen therapy is routinely used during general anesthesia to prevent hypoxemia; however, excessive oxygen administration may result in hyperoxia, which has been associated with adverse cardiovascular and pulmonary effects. Standard pulse oximetry may not adequately detect hyperoxia when oxygen saturation values are high.\n\nIn this prospective comparative study, patients will receive oxygen titration guided either by SpO₂ alone or by combined ORi and SpO₂ monitoring. The primary outcome is the incidence of intraoperative hyperoxemia, assessed by arterial blood gas analysis. Secondary outcomes include intraoperative oxygenation parameters and hemodynamic variables.",[588,589,590,591],"Hyperoxemia","Intraoperative Oxygen Therapy","Beach Chair Position","Cerebral Oxygenation",[77,593,594,595,596,597,598,271,599,600],"ORİ","FiO2 titration","Hyperoxia","Pulse oximetry","Arterial blood gas","Near-infrared spectroscopy","Beach chair position","Orthopedic surgery","2026-02-09",{"date":603,"type":33},"2026-02-11",{"date":605,"type":22},"2026-02-15",{"date":607,"type":22},"2026-07-31",{"name":39,"class":40},{"id":610,"slug":611,"hasResults":12,"nctId":612,"briefTitle":613,"officialTitle":614,"acronym":615,"eligibilityCriteria":616,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":617,"targetDuration":4,"studyType":193,"phases":619,"briefSummary":620,"conditions":621,"keywords":625,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":601,"lastUpdatePostDateStruct":632,"startDateStruct":633,"completionDateStruct":634,"leadSponsor":635,"locationsCount":91},"100624014","effects-of-ankle-block-on-postoperative-analgesia-in-diabetic-and-non-diabetic-patients-100624014","NCT07404124","Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients","Comparison of Sensory and Motor Block Characteristics and Postoperative Analgesic Consumption After Ultrasound-Guided Ankle Block in Diabetic and Non-Diabetic Patients Undergoing Lower Extremity Surgery","ANKLE-DM","Inclusion Criteria:\n\n* Adults aged 18 years and older.\n* Patients scheduled for lower extremity surgery under ultrasound-guided ankle block as part of routine clinical care.\n* Patients able to provide written informed consent.\n* Availability of complete perioperative data including blood glucose levels, -HbA1c values, pain scores, and postoperative analgesic consumption.\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent.\n* Failure of ankle block requiring conversion to another anesthesia technique.\n* Known coagulation disorders contraindicating peripheral nerve block.\n* Active infection at the site of block application.\n* Chronic opioid or analgesic use, chronic alcohol use, or substance abuse.\n* History of diabetic ketoacidosis or hyperosmolar hyperglycemic state.\n* Severe renal or hepatic insufficiency.\n* Known allergy to local anesthetics such as lidocaine or bupivacaine.\n* Inability to perform perioperative blood glucose monitoring.\n* Cognitive impairment or psychiatric conditions interfering with study participation or data collection.",{"count":618,"type":22},46,[195],"This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery. The study will compare diabetic and non-diabetic patients and will also assess the impact of glycemic control on block onset time and postoperative analgesic consumption.\n\nAnkle block is commonly used in patients undergoing foot and ankle surgery, particularly in those with diabetes, peripheral neuropathy, or vascular disease, when general or neuraxial anesthesia may not be suitable. Previous studies suggest that diabetic neuropathy and impaired glycemic control may influence the onset and duration of peripheral nerve blocks.\n\nAdult patients scheduled for lower extremity surgery under ankle block will be included. All procedures will be performed as part of routine clinical care, and no additional interventions will be applied for research purposes. Sensory and motor block onset times, postoperative pain scores, opioid consumption within the first 24 hours, and patient and surgeon satisfaction will be recorded.\n\nThe results of this study are expected to provide clinically relevant information regarding the effects of diabetes and glycemic control on ankle block characteristics and postoperative analgesia.",[622,623,624],"Diabetes Mellitus","Diabetic Neuropathy","Postoperative Pain Management",[626,564,627,622,623,628,560,629,630,631],"Ankle Block","Peripheral Nerve Block","Glycemic Control","HBA1C","Lower Extremity Surgery","Opioid Consumption",{"date":603,"type":33},{"date":546,"type":22},{"date":495,"type":22},{"name":39,"class":40},{"id":637,"slug":638,"hasResults":12,"nctId":639,"briefTitle":640,"officialTitle":641,"acronym":4,"eligibilityCriteria":642,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":524,"enrollmentInfo":643,"targetDuration":4,"studyType":193,"phases":644,"briefSummary":645,"conditions":646,"keywords":650,"overallStatus":218,"whyStopped":4,"lastUpdateSubmitDate":652,"lastUpdatePostDateStruct":653,"startDateStruct":655,"completionDateStruct":657,"leadSponsor":659,"locationsCount":91},"100619602","suprascapular-nerve-block-and-proprioception-in-hemiplegic-shoulder-pain-a-randomized-controlled-study-100619602","NCT07346755","Suprascapular Nerve Block and Proprioception in Hemiplegic Shoulder Pain: A Randomized Controlled Study","Effects of Suprascapular Nerve Block on Proprioception in Hemiplegic Shoulder Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Presence of shoulder pain on the hemiplegic side with a Numeric Rating Scale (NRS) score \\> 3\n* At least 1 month since the cerebrovascular event (subacute and chronic stroke patients)\n* Active shoulder flexion range of motion \\> 90 degrees (required for the application of the laser pointer-assisted joint position sense test)\n* First-ever, unilateral hemiplegia\n\nExclusion Criteria:\n\n* Mini-Mental State Examination score \\\u003C 24 indicating cognitive impairment\n* Presence of aphasia\n* Shoulder spasticity with a Modified Ashworth Scale score \\> 2\n* Brunnstrom upper extremity motor stage \\\u003C 3\n* Botulinum toxin type A injection within the last 3 months to muscles affecting shoulder joint movement (trapezius, levator scapulae, pectoralis major, deltoid, serratus anterior, latissimus dorsi, rhomboids, teres major, biceps, coracobrachialis, triceps, supraspinatus, subscapularis, infraspinatus, and teres minor)\n* Pre-existing shoulder pathology causing pain in the hemiplegic shoulder\n* Presence of neglect syndrome\n* Complex regional pain syndrome, central pain, traumatic brachial plexus injury\n* Change in pain medication during the study period\n* Hypersensitivity to the medication used for suprascapular nerve block (lidocaine)\n* Adhesive capsulitis (frozen shoulder)\n* Other shoulder pathologies such as fractures or joint replacement",{"count":431,"type":22},[195],"The purpose of this prospective randomized controlled clinical trial is to evaluate the effect of suprascapular nerve block on shoulder joint proprioception in stroke patients with hemiplegic shoulder pain.\n\nFourteen patients aged 18-80 years with hemiplegic shoulder pain will be randomized into two groups. One group will receive suprascapular nerve block followed by a standardized physical therapy program, while the control group will receive the same physical therapy program alone.\n\nThe primary outcome is shoulder joint proprioception. Secondary outcomes include pain intensity, shoulder range of motion, motor recovery, stroke-specific quality of life, and upper extremity functional outcomes.\n\nThe results of this study are expected to clarify the role of suprascapular nerve block on proprioception and rehabilitation outcomes in patients with hemiplegic shoulder pain.",[647,648,649],"Hemiplegic Shoulder Pain","Proprioception","Suprascapular Nerve Block",[647,648,651,532],"Suprascapular nerve block","2026-01-18",{"date":654,"type":33},"2026-01-21",{"date":656,"type":33},"2025-05-01",{"date":658,"type":22},"2026-05",{"name":39,"class":40},{"id":661,"slug":662,"hasResults":12,"nctId":663,"briefTitle":664,"officialTitle":665,"acronym":4,"eligibilityCriteria":666,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":156,"enrollmentInfo":667,"targetDuration":668,"studyType":24,"phases":4,"briefSummary":669,"conditions":670,"keywords":672,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":677,"lastUpdatePostDateStruct":678,"startDateStruct":680,"completionDateStruct":682,"leadSponsor":684,"locationsCount":91},"100573136","magnetic-resonance-imaging-parameters-in-patients-with-subacromial-impingement-syndrome-100573136","NCT06742359","Magnetic Resonance Imaging Parameters in Patients with Subacromial Impingement Syndrome","Relationship of Magnetic Resonance Imaging Parameters with Shoulder Function and Pain in Patients with Subacromial Impingement Syndrome","Inclusion Criteria:\n\n1. To be between the ages of 18-65\n2. Shoulder pain for at least six weeks\n\nExclusion Criteria:\n\n1. Presence of a rheumatologic disease,\n2. Presence of neurological disease\n3. Pregnancy\n4. Symptomatic osteoarthritis of the shoulder, shoulder instability, pathologies of the tendon of the long head of the biceps, glenoid injuries and partial tears greater than 3 mm and full-thickness tears of the rotator cuff\n5. Corticosteroid, hyaluronic acid and\u002For PRP injection in the shoulder area within the last 3 months",{"count":100,"type":22},"2 Months","Shoulder pain is the third most common musculoskeletal pain complaint in the world with an incidence of 7-30%. Subacromial impingement syndrome (SIS) is the most common cause of shoulder pain. Imaging in impingement syndrome is usually based on different imaging modalities. X-ray, magnetic resonance imaging (MRI) and ultrasound are the most commonly used, and MRI is considered by many authors to be the most reliable imaging modality for evaluation of the rotator cuff because it allows evaluation of soft tissues as well as bony abnormalities such as subacromial osteophytes and acromioclavicular joint capsular hypertrophy. MRI allows the diagnosis of rotator cuff tears with greater interobserver reliability than ultrasound in assessing tear size, retraction and atrophy. Few studies have investigated the impact of pathologic findings on MRI on the degree of symptoms and functional impairment seen in these patients. The aim of this study was to investigate the relationship between shoulder pain and function and MRI findings in patients with subacromial impingement syndrome.",[671],"Subacromial Impingement Syndrome",[673,674,675,676],"Subacromial impingement syndrome","pain","function","magnetic resonance imaging","2024-12-20",{"date":679,"type":33},"2024-12-27",{"date":681,"type":22},"2025-01-31",{"date":683,"type":22},"2025-04-30",{"name":39,"class":40},{"id":686,"slug":687,"hasResults":12,"nctId":688,"briefTitle":689,"officialTitle":690,"acronym":691,"eligibilityCriteria":692,"healthyVolunteers":17,"sex":18,"minAge":478,"maxAge":693,"enrollmentInfo":694,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":695,"conditions":696,"keywords":698,"overallStatus":218,"whyStopped":4,"lastUpdateSubmitDate":703,"lastUpdatePostDateStruct":704,"startDateStruct":706,"completionDateStruct":708,"leadSponsor":710,"locationsCount":91},"100560097","ultrasonographic-evaluation-of-parasternal-intercostal-muscles-in-stroke-patients-100560097","NCT06572709","Ultrasonographic Evaluation of Parasternal Intercostal Muscles in Stroke Patients","Ultrasonographic Evaluation of Parasternal Intercostal Muscles and Their Correlation With Respiratory Function Test in Stroke Patients","UEPIMSP","Inclusion Criteria:\n\n* Ischemic or Hemorrhagic stroke patients, Stroke duration \\>6 months, Mini-mental test score \\>24\n\nExclusion Criteria:\n\n* Individuals with acute or chronic lung disease, Patients with a history of thoracic or abdominal surgery, Patients with other neuromuscular diseases, Aphasia type with impaired understanding, Facial paralysis","90 Years",{"count":67,"type":22},"Ultrasonographic evaluation of parasternal intercostal muscles and to determine whether there is a correlation with PFT parameters in stroke patients",[528,697],"Respiratory Muscle",[541,699,700,701,702],"intercostal muscle","pulmonary function test","respiratory muscle","ultrasound","2024-08-23",{"date":705,"type":33},"2024-08-27",{"date":707,"type":33},"2024-08-07",{"date":709,"type":22},"2024-09-04",{"name":39,"class":40},""]