[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100609250","analgesic-effect-of-tens-waa-combined-with-tramadol-hydrochloride-during-oocyte-retrieval-surgery-100609250",false,"NCT07212127","Analgesic Effect of TENS-WAA Combined With Tramadol Hydrochloride During Oocyte Retrieval Surgery","Analgesic Effect of Transcutaneous Electrical Nerve Stimulation Based on Wrist-Ankle Acupuncture Theory Combined With Tramadol Hydrochloride During Oocyte Retrieval Surgery","Inclusion Criteria:\n\n* Females aged between 21 and 42 years.\n* Patients diagnosed with infertility requiring oocyte retrieval for in vitro fertilisation-embryo transfer.\n* Body Mass Index (BMI) 18.5 ≤ BMI ≤ 29.9 kg\u002Fm².\n* Regular menstrual cycles with ultrasound monitoring demonstrating dominant follicle development and ovulation during the natural cycle; good ovarian reserve: follicle-stimulating hormone (FSH) \\\u003C 10 IU\u002FL, antral follicle count (AFC) \\> 6, anti-Müllerian hormone (AMH) \\> 1.5 ng\u002Fml.\n* Undergoing ovarian stimulation therapy using follicle-stimulating hormone (FSH) or gonadotropin protocols.\n* Electing tramadol hydrochloride injection for analgesia during oocyte retrieval.\n* Voluntary participation with signed written informed consent.\n\nExclusion Criteria:\n\n* History of other chronic pain conditions, or prolonged use of opioid medications, history of anaesthetic drug addiction, or chronic alcohol abuse.\n* Severe pelvic adhesions.\n* Presence of pacemakers or other implanted medical electronic devices.\n* Concurrent use of high-frequency surgical equipment, artificial heart-lung machines, medical shortwave therapy, or microwave therapy devices.\n* Presence of scarring or skin lesions at electrode application sites.\n* Severe anxiety, depression, or other psychiatric conditions impairing accurate description of sensations, or any other disorders potentially affecting pain perception.\n* Conditions contraindicating or affecting oocyte retrieval, such as coagulation disorders, acute pelvic inflammation, vaginitis, trichomoniasis, endometriomas, ovarian cysts.\n* Individuals with laparoscopically and\u002For ultrasonographically confirmed endometriosis.\n* Patients with ovarian hyporesponsiveness following conventional ovarian stimulation medication.","FEMALE","21 Years","42 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is a single-centre randomised controlled trial. It aimed to evaluate the efficacy and safety of transcutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory(TENS-WAA) combined with tramadol hydrochloride for analgesia during transvaginal ultrasound-guided oocyte retrieval, by comparing the analgesic effects and the prevention of postoperative nausea and vomiting between the TENS-WAA combined with tramadol hydrochloride group (experimental group) and the sham TENS-WAA combined with tramadol hydrochloride group (control group). Participants were randomly assigned to the experimental or control group. The experimental group received percutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory 30 minutes prior to the procedure, at a frequency of 2Hz with current intensity adjusted to the maximum tolerable level.Tramadol hydrochloride 100mg was administered intramuscularly 20 minutes before surgery. The control group received sham stimulation at the lowest intensity under identical conditions. The primary outcome measure was the Visual Analogue Scale (VAS). Secondary outcome measures included skin conductance response, postoperative nausea scale, and vomiting scale.",[27,28],"Oocyte Retrieval for IVF","Pain","NOT_YET_RECRUITING","2025-09-30",{"date":32,"type":33},"2025-10-08","ACTUAL",{"date":35,"type":21},"2025-11-08",{"date":37,"type":21},"2026-12-31",{"name":39,"class":40},"First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":41},"100581376","transcranial-magnetic-stimulation-synchronized-with-motor-task-training-for-post-stroke-rehabilitation-100581376","NCT06849505","Transcranial Magnetic Stimulation Synchronized with Motor Task Training for Post-Stroke Rehabilitation","Closed - Loop Neuromodulation of Post - Stroke Motor Dysfunction by Transcranial Magnetic Stimulation Synchronized with Specific Motor Task Training","TMS","Inclusion Criteria:\n\n1. The patient is first diagnosed with stroke through neurological examination, CT or MRI scan.\n2. The vital signs are stable and there is a certain degree of upper limb motor dysfunction.\n3. The age is between 20 and 80 years old.\n4. The cognitive ability is not significantly affected and the patient can cooperate with various examinations and assessments, with a MMSE score ≥ 20 points.\n5. There are no serious complications (such as pneumonia, heart failure, urinary tract infection or malnutrition).\n6. There is no pathological condition that is a contraindication for TMS in the medical history (for example, patients with metal in the brain, such as aneurysm clips, patients with a cardiac pacemaker, pregnant women, or those with a history of epileptic seizures).\n7. The patient or guardian agrees to sign the informed consent form.\n\nExclusion Criteria:\n\n1. Patients with severe heart, lung, liver, kidney diseases and malignant tumors;\n2. Those with a history of aphasia, severe cognitive impairment or mental illness;\n3. Patients who have had a history of epileptic seizures in the last month or are taking anti-epileptic drugs recently;\n4. Those with severe visual or hearing impairments, unable to communicate normally;\n5. People with metal implants, pacemakers, skull defects or other conditions that prevent them from undergoing TMS.","ALL","20 Years","80 Years",{"count":54,"type":21},15,[24],"The goal of this clinical trials is to investigate the effectiveness of individualized online repetitive transcranial magnetic stimulation (rTMS) in enhancing upper limb motor rehabilitation during the subacute and chronic phase of stroke. It will also learn about the safety of individualized online rTMS intervention methods. The main questions it aims to answer are:\n\nDoes rTMS synchronized with motor training improve motor rehabilitation in patients with the ability to induce motor evoked potentials(MEPs)？ Dose individualized rTMS synchronized with motor training improve motor rehabilitation in patients without the ability to induce MEPs? Researchers will compare online rTMS to offline and sham stimulation in patients with MEPs to see if online rTMS works to alleviate motor dysfunction in preliminary trials. And compare individualized online rTMS to non-individualized online rTMS and sham in patients without MEPs to see if individualized online rTMS works to alleviate motor dysfunction in Randomized, double-blinded, and controlled trials.\n\nParticipants will:\n\nrandomized to one group acoording to the MEP condition of each person; receive rTMS treatment for 10 days, with 5 working days per week for a total of two weeks; receive magnetic resonance imaging (MRI) and electroencephalogram (EEG) evaluations before and after the entire treatment; conduct scales and MEP assessment one day before the treatment, as well as one day, one month, and three months after the treatment.",[58,59],"Stroke","Upper Extremity Parasis",[61,62,48,63,64],"stroke","individualized","motor dysfunction","online","RECRUITING","2025-02-25",{"date":68,"type":33},"2025-02-27",{"date":70,"type":33},"2024-07-02",{"date":72,"type":21},"2025-06-30",{"name":39,"class":40},""]