[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fondazione EMN Italy Onlus\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100650280","validating-dw-mri-and-fat-fraction-in-multiple-myeloma-post-asct-the-rac-fat-study-100650280",false,"NCT07746232","Validating DW-MRI and Fat Fraction in Multiple Myeloma Post-ASCT: The RAC-FAT Study\"","Multicenter Observational Study for the Validation of the Predictive Role of Diffusion-Weighted Whole-body MRI (DW-MRI) Imaging Response According to MY-RADS Criteria (RAC Score) and Fat Fraction (rFF%) After Autologous Stem Cell Transplantation in Multiple Myeloma Patients Treated With First-Line Anti-CD38-Based Therapy (RAC-FAT Study)","Inclusion criteria:\n\n* Newly diagnosed MM participants eligible for ASCT, treated with anti-CD38-based quadruplet induction therapy and ASCT, with post-ASCT\u002Fpremaintenance DW-MRI available (in tandem ASCT, DW-MRI after second ASCT will be considered).\n* Age ≥18 years.\n* Participant must sign an informed consent form (ICF) that he or she understands the purpose of, and procedures required for the trial and is willing to participate in the trial.\n\nExclusion Criteria:\n\n\\- Absence of post-ASCT\u002Fpre-maintenance DW-MRI.","ALL","18 Years",{"count":19,"type":20},92,"ESTIMATED","OBSERVATIONAL","This is a multicenter, observational, retrospective-prospective study designed to validate the predictive role of advanced imaging in patients with newly diagnosed multiple myeloma (NDMM). The main purpose of this study is to estimate the prevalence of radiological response categories (Response Assessment Category, RAC score) and evaluate the predictive value of relative Fat Fraction (rFF%) using Diffusion-Weighted Whole-Body Magnetic Resonance Imaging (DW-MRI) in patients who have undergone autologous stem cell transplantation (ASCT) after receiving first-line anti-CD38-based quadruplet induction therapy.",[24],"Multiple Myeloma (MM)",[26,27,28,29,30,31,32,33],"Newly diagnosed multiple myeloma (NDMM)","Transplant-eligible (TE)","Diffusion-weighted whole-body MRI (DW-MRI)","MY-RADS criteria","Response Assessment Category (RAC score)","Fat Fraction (rFF%)","Autologous Stem Cell Transplantation (ASCT)","Anti-CD38-based therapy","NOT_YET_RECRUITING","2026-07-30",{"date":37,"type":38},"2026-08-04","ACTUAL",{"date":40,"type":20},"2026-08",{"date":42,"type":20},"2030-08",{"name":44,"class":45},"Fondazione EMN Italy Onlus","OTHER",10,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":57,"studyType":21,"phases":4,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},"100439345","a-physician--patient-powered-cohort-registry-my-myeloma-100439345","NCT05001087","A \"Physician & Patient-powered\" Cohort Registry (MY MYELOMA)","A \"Physician & Patient-powered\" Cohort Registry","MY MYELOMA","Inclusion Criteria:\n\n* Patients of both sexes\n* Age ≥ 18 years\n* Diagnosis of active\u002Fsymptomatic multiple myeloma (according to CRAB and biological parameters) no earlier than 1st January 2019\n* Able and willing to sign an informed consent form\n\nExclusion Criteria:\n\n* None considered",{"count":56,"type":20},1900,"3 Years","The aim of this observational study is the creation of a national multiple myeloma registry to monitor the current routine clinical practice in Italy and describe the standard of care adopted for the diagnosis and treatment of patients with multiple myeloma in the different Italian hematology centers.",[60],"Multiple Myeloma","RECRUITING","2025-02-25",{"date":64,"type":38},"2025-02-27",{"date":66,"type":38},"2021-03-16",{"date":68,"type":20},"2027-03-31",{"name":44,"class":45},27,""]