[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"George Eastman Dental Hospital, Italy\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100655649","early-phase-1-reconstructive-treatment-of-peri-implantitis-with-electrolytic-decontamination-versus-titanium-brushes-100655649",false,"NCT07814391","Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes","Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes: a Randomized Controlled Trial","Galvo vs mech","Inclusion Criteria:\n\n* Implants with peri-implantitis (defined according to 2017 World Workshop definitions)\n* contained defects with infra osseous component amenable to reconstructive treatment\n* fixed and removable superstructures\n* patients with no systemic conditions affecting healing (uncontrolled diabetes mellitus, chronic corticosteroid use, autoimmune conditions affecting connective tissue)\n* smoking more than 10 cigarettes\n\nExclusion Criteria:\n\n* mobile implants\n* non removable crowns (both cement or screw retained) that cannot be removed prior to surgery","ALL","18 Years",{"count":20,"type":21},38,"ESTIMATED","INTERVENTIONAL",[24],"EARLY_PHASE1","Implants diagnosed with peri-implantitis and amenable for bone reconstructive treatment will be enrolled in the study. The implants will randomly be treated with either an electrolytic or a mechanical cleaning of the implant surface (with titanium brushes). In all cases, a bone graft will be used to rebuild missing bone.",[27],"Peri-Implantitis and Peri-implant Mucositis",[29,30,31,32],"electrolytic cleaning","reconstructive treatment","demineralized bovine bone mineral (DBBM)","titanium brush","NOT_YET_RECRUITING","2026-09-04",{"date":36,"type":37},"2026-09-11","ACTUAL",{"date":39,"type":21},"2027-01",{"date":41,"type":21},"2027-04",{"name":43,"class":44},"George Eastman Dental Hospital, Italy","OTHER",""]