[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Giresun University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":170},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,46,83,116,145],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100651091","gabapentin-and-pregabalin-effects-on-inflammation-and-cardiac-function-in-peripheral-neuropathic-pain-100651091",false,"NCT07755514","Gabapentin and Pregabalin Effects on Inflammation and Cardiac Function in Peripheral Neuropathic Pain","Translational Analysis of Changes in Inflammatory Biomarkers and Subclinical Cardiac Function Associated With Gabapentin and Pregabalin Use in Patients With Peripheral Neuropathic Pain: A Prospective Controlled Cohort Study","Inclusion Criteria:\n\n* Patient Cohorts:Age 18 years or older.A clinical diagnosis of peripheral neuropathic pain based on medical history, physical and neurological examination, and, when available, electrophysiological testing or imaging.A determination, following routine clinical evaluation, that initiation of gabapentin or pregabalin is clinically appropriate.Ability to complete baseline assessments before the first dose.Ability and willingness to provide written informed consent.Healthy Controls:Age 18 years or older.Attendance at the cardiology department for a routine health examination or check-up.No peripheral neuropathy, chronic neuropathic pain, gabapentin or pregabalin use, or clinically significant cardiovascular disease based on standard clinical screening.Eligibility, as far as possible, for frequency matching with the patient cohorts by age, sex, and body mass index.Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Known or newly identified heart failure.2. Clinically significant valvular heart disease, cardiomyopathy, significant cardiac arrhythmia, previous acute coronary syndrome, or other significant structural heart disease.3. Active or recent acute infection.4. Active autoimmune or systemic inflammatory disease.5. Active malignancy.6. Recent major surgery, severe trauma, or acute cardiovascular event.7. Current systemic corticosteroid or immunosuppressive treatment.8. Advanced renal or hepatic dysfunction.9. Uncontrolled thyroid disease.10. Pregnancy or breastfeeding.11. Any acute clinical condition likely to substantially affect baseline biomarker measurements.12. Current use of gabapentin or pregabalin at baseline.13. Inability to complete baseline measurements before the first dose of gabapentin or pregabalin.14. Any other condition that, in the investigator's judgment, would prevent safe or appropriate participation in the study",true,"ALL","18 Years",{"count":20,"type":21},75,"ESTIMATED","1 Month","OBSERVATIONAL","This prospective, controlled, observational cohort study will evaluate short-term changes in inflammatory biomarkers and subclinical cardiac function in adults with peripheral neuropathic pain who are prescribed gabapentin or pregabalin as part of routine clinical care. A total of 75 participants will be enrolled: 25 patients starting gabapentin, 25 patients starting pregabalin, and 25 healthy controls without peripheral neuropathy or chronic neuropathic pain. Treatment selection and dose adjustments will be determined by the treating physician and will not be assigned by the study investigators. Participants will be assessed at baseline and again after 30 ± 7 days. Assessments will include clinical information, pain severity, routine laboratory results, inflammatory biomarkers, and standard transthoracic echocardiography. No additional blood will be collected solely for research; leftover serum from routine testing will be used. The primary aim is to compare changes over time between the gabapentin and pregabalin groups, while the healthy control group will provide a reference for interpretation.",[26],"Peripheral Neuropathic Pain",[28,29,30,31,32,33],"gabapentin","pregabalin","Inflammatory Biomarkers","Subclinical Cardiac Dysfunction","Echocardiography","Neuropathic Pain","NOT_YET_RECRUITING","2026-08-05",{"date":37,"type":38},"2026-08-10","ACTUAL",{"date":40,"type":21},"2026-08-15",{"date":42,"type":21},"2026-10-15",{"name":44,"class":45},"Giresun University","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},"100649592","effect-of-structured-education-for-family-members-of-intensive-care-patients-undergoing-tracheostomy-100649592","NCT07737353","Effect of Structured Education for Family Members of Intensive Care Patients Undergoing Tracheostomy","The Effect of Structured Education Provided to Family Members of Patients Undergoing Tracheostomy in the Intensive Care Unit on Anxiety, Psychological Well-Being, and Satisfaction With Care: A Randomized Controlled Trial","TRACH-FAMILY","Inclusion Criteria:\n\n* Family member or primary caregiver of a patient scheduled to undergo tracheostomy in one of the participating intensive care units.\n* Aged 18 years or older.\n* Able to read, understand, and communicate in Turkish.\n* Willing to participate in the study.\n* Provides written informed consent.\n* Actively involved in the patient's care and treatment process.\n\nExclusion Criteria:\n\n* Diagnosed with a severe psychiatric disorder.\n* Severe hearing, visual, or cognitive impairment that prevents completion of the study questionnaires.\n* Communication problems that prevent participation in the data collection process.\n* Declines to participate in the study.",{"count":55,"type":21},84,"INTERVENTIONAL",[58],"NA","Family members of patients undergoing tracheostomy in the intensive care unit frequently experience anxiety, uncertainty, and concerns regarding the patient's care. This randomized controlled trial aims to evaluate the effect of structured education provided to family members of patients undergoing tracheostomy in the intensive care unit on state anxiety, psychological well-being, and satisfaction with care. Participants will be randomly assigned to either the intervention or control group. The intervention group will receive structured education before tracheostomy, whereas the control group will receive routine information. Outcomes will be assessed before tracheostomy, on the first day after tracheostomy, and one week after the procedure.",[61,62,63],"Tracheostomy","Critical Illness","Intensive Care",[65,66,67,61,68,69,70,71,72],"Structured Education","Family Members","Intensive Care Unit","Anxiety","Psychological Well-Being","Satisfaction With Care","Family-Centered Care","Randomized Controlled Trial","RECRUITING","2026-07-27",{"date":76,"type":38},"2026-07-30",{"date":78,"type":38},"2026-05-18",{"date":80,"type":21},"2027-05-18",{"name":44,"class":45},1,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":91,"minAge":18,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":56,"phases":94,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":82},"100632994","the-effect-of-mobile-based-perioperative-education-on-urinary-incontinence-and-erectile-function-after-radical-prostatectomy-100632994","NCT07520916","The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy","The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy: A Randomized Controlled Trial","MPE-RP","Inclusion Criteria:\n\n* Patients diagnosed with prostate cancer and scheduled for elective radical prostatectomy (open, laparoscopic, or robotic)\n* Aged 18 years or older\n* Planned to undergo surgery at the study center(s)\n* Able to use a smartphone and having sufficient digital literacy to operate the mobile application\n* Provided written informed consent after being informed about the study\n\nExclusion Criteria:\n\n* Pre-existing urinary incontinence or erectile dysfunction before surgery\n* Severe cognitive impairment or severe visual or hearing impairment\n* Previous pelvic radiotherapy or a history of major pelvic surgery\n* Presence of severe comorbidity or terminal illness that may interfere with adherence to the study protocol\n* Technological insufficiency preventing the use of the mobile application","MALE",{"count":93,"type":21},78,[58],"This prospective randomized controlled study aims to evaluate the effect of mobile-based perioperative education on postoperative urinary incontinence and erectile function in patients undergoing radical prostatectomy. Patients scheduled for radical prostatectomy will be assigned to either an intervention group or a control group. The intervention group will receive standard care plus a structured mobile application-based perioperative education program including video-assisted pelvic floor muscle training, perioperative education modules, reminders, and follow-up components. The control group will receive routine perioperative care and standard patient education. Data will be collected preoperatively, after urinary catheter removal, and at 1 month and 3 months after surgery. The primary outcomes are urinary incontinence and erectile function, assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), the International Index of Erectile Function-5 (IIEF-5), and a 24-hour pad assessment. Secondary outcomes include lower urinary tract symptoms and disease-specific quality of life assessed by the International Prostate Symptom Score (IPSS), psychological status assessed by the Depression Anxiety Stress Scale-21 (DASS-21), and system usability assessed by the Turkish version of the Computer System Usability Questionnaire-Short Version (T-CSUQ-SV)",[97,98,99],"Prostate Cancer (Post Prostatectomy)","Urinary Incontinence (UI)","Erectile Dysfunction Following Radical Prostatectomy",[101,102,103,104,105,106,107],"Radical Prostatectomy","Mobile Health","mHealth","Perioperative Education","Pelvic Floor Muscle Training","Urinary Incontinence","Erectile Function","2026-04-03",{"date":110,"type":38},"2026-04-09",{"date":112,"type":38},"2026-04-02",{"date":114,"type":21},"2027-04-02",{"name":44,"class":45},{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":4,"eligibilityCriteria":122,"healthyVolunteers":16,"sex":17,"minAge":123,"maxAge":18,"enrollmentInfo":124,"targetDuration":4,"studyType":56,"phases":126,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":82},"100626254","digital-privacy-awareness-in-gifted-students-100626254","NCT07433244","Digital Privacy Awareness in Gifted Students","Gifted\u002FTalented Students' Digital Privacy Perceptions And Concerns In The Context Of Their Digital Literacy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Identified as a gifted or talented student and enrolled in a Science and Art Center (BİLSEM).\n* Currently enrolled in grades 9 through 12.\n* Aged between 14 and 18 years.\n* Actively using digital devices and online platforms.\n* Willing to participate voluntarily in the study.\n* Informed consent obtained from the participant and, where required, from a parent or legal guardian.\n\nExclusion Criteria:\n\n* Not identified as a gifted or talented student.\n* Not enrolled in a Science and Art Center (BİLSEM).\n* Outside the specified age range.\n* Inability to participate in the educational sessions or complete the assessment instruments.\n* Withdrawal of consent at any stage of the study.","14 Years",{"count":125,"type":21},128,[58],"This randomized controlled trial aims to examine gifted and talented students' perceptions and concerns regarding digital privacy within the context of their digital literacy. The study evaluates the effectiveness of a structured digital privacy education intervention designed to increase awareness and informed decision-making in digital environments. Gifted students are randomly assigned to an intervention group or a control group receiving standard practice. Data are collected using validated measures of digital privacy perception, digital literacy, and privacy-related concerns. The findings are expected to contribute to the development of evidence-based digital literacy and privacy education practices for gifted learners.",[129,130,131],"Digital Privacy","Digital Literacy","Online Privacy Awareness",[133,129,130,134,135,136,72],"Gifted Students","Privacy Awareness","Online Safety","Adolescents","2026-02-21",{"date":139,"type":38},"2026-02-25",{"date":141,"type":38},"2024-09-15",{"date":143,"type":21},"2026-04",{"name":44,"class":45},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":152,"targetDuration":4,"studyType":56,"phases":154,"briefSummary":155,"conditions":156,"keywords":158,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":167,"leadSponsor":169,"locationsCount":82},"100614713","the-effect-of-virtual-reality-100614713","NCT07283172","The Effect of Virtual Reality","The Effect of Virtual Reality on Pain and Anxiety During Chest Tube Removal in Patients With Cardiac Surgery","Inclusion Criteria:\n\n* 18 years of age or older,\n* Undergone open heart surgery and have a chest tube,\n* Able to communicate verbally,\n* Have not previously received any psychiatric diagnosis or treatment and are not taking psychiatric medication,\n* Hemodynamic status is stable,\n* Patients who agree to participate in the study will be included.\n\nExclusion Criteria:\n\n* Patients who used analgesic medication immediately before the chest tube removal procedure,\n* Patients with a history of chronic pain who routinely use analgesic medication,\n* Patients who wear prescription glasses and have vision problems will not be included.",{"count":153,"type":21},60,[58],"Chest tubes are routinely required during cardiothoracic procedures in open-heart surgeries. Postoperatively, these tubes are typically removed within 24-48 hours, and the removal process often causes patients to experience significant pain and discomfort due to the force applied. Among non-pharmacological strategies for managing procedural pain, distraction techniques are commonly used to divert patients' attention away from painful stimuli. In this context, the use of virtual reality (VR) headsets has recently emerged as an innovative method for pain management, effectively redirecting attention during invasive interventions.\n\nThe aim of this study is to evaluate the effects of virtual reality on pain and anxiety levels during chest tube removal. This research is designed as a randomized controlled experimental trial. The study population will consist of patients undergoing open-heart surgery at the Cardiovascular Surgery Clinic of Giresun Training and Research Hospital. A total of 60 patients who meet the inclusion criteria and are representative of the study population will be recruited. Data will be collected using a Patient Identification Form developed by the researchers to assess sociodemographic characteristics, the Visual Analog Scale (VAS), and the State Anxiety Inventory. Participants will be randomly assigned to either the experimental or control group. Patients in the control group will receive routine care without additional intervention. In the experimental group, patients will be thoroughly informed about the VR procedure, including instructions on how to use the headset, details of the video content, and an explanation of the upcoming intervention. Five minutes before chest tube removal, the VR headset will be placed on the patient, and a video will be shown. The physician will then remove the chest tube(s) while the patient is engaged in the VR session. Pain intensity will be assessed at three time points: before chest tube removal, immediately after the procedure, and 20 minutes post-procedure. Anxiety levels will be evaluated twice: before the procedure and 20 minutes afterward. Data will be analyzed using SPSS version 22.0. Descriptive statistics, chi-square tests, and independent t-tests will be used for group comparisons, while repeated measures analysis of variance (R-ANOVA) will be employed for repeated measures.",[157],"The Effects of Virtual Reality on Pain and Anxiety Levels During Chest Tube Removal",[159,160,161,162,68],"Cardiac Surgery","Chest Tube","Virtual Reality","Pain","2025-12-02",{"date":165,"type":38},"2025-12-15",{"date":165,"type":21},{"date":168,"type":21},"2026-07-15",{"name":44,"class":45},""]