[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Guang Ning\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":76},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100652418","efficacy-of-different-dietary-pattern-in-long-term-weight-management-100652418",false,"NCT07773558","Efficacy of Different Dietary Pattern in Long-term Weight Management","A Multicenter Randomized Controlled Trial Evaluating the Efficacy of Different Dietary Pattern Management Programs in Long-term Weight Management","EDI-Weight","Inclusion Criteria:\n\n1. Male or female, aged 20-59 years\n2. Obesity defined by BMI≥28 kg\u002Fm²;\n3. With willingness to undergo dietary intervention for weight loss.\n\nExclusion Criteria:\n\n1. BMI≥40 kg\u002Fm²;\n2. Suffering from gastrointestinal diseases that affect food digestion and absorption (such as functional bowel disorders, etc.), or having a known history of food allergies, or having a history of previous gastrointestinal surgery that affects dietary intervention;\n3. Suffering from diseases that affect body weight or glucose and lipid metabolism (such as uncontrolled hyponatremia, thyroid dysfunction, secondary hypertension, type 1 diabetes, Cushing's syndrome, etc.);\n4. Currently undergoing pharmacological treatment that affects body weight or glucose and lipid metabolism (such as thyroid medications, corticosteroids, antidiabetic drugs, lipid-lowering drugs, diuretics, etc.);\n5. Having been diagnosed with clinical cardiovascular disease (coronary heart disease, stroke, heart failure, etc.) or malignancy;\n6. Suffering from severe liver or kidney disease (alanine aminotransferase or serum creatinine levels exceeding 2 times the upper limit of normal);\n7. Pregnant, breastfeeding, or women of childbearing potential who are not using contraception;\n8. Any condition deemed by the investigator to affect study compliance;\n9. Currently participating in another interventional study or having participated in another drug clinical trial within the past 3 months.","ALL","20 Years","59 Years",{"count":21,"type":22},800,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study is a nationwide multi-center, long-term randomized controlled clinical trial, aiming to evaluate the effects of individualized dietary pattern management programs compared to traditional energy-restricted diets in weight management.",[28,29],"Obesity and Overweight","Dietary Intervention",[31,32,33],"dietary","weight","obesity","NOT_YET_RECRUITING","2026-08-14",{"date":37,"type":38},"2026-08-19","ACTUAL",{"date":40,"type":22},"2026-09-01",{"date":42,"type":22},"2029-06-01",{"name":44,"class":45},"Guang Ning","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":18,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100348030","china-diabetes-registry-by-metabolic-management-center-100348030","NCT03811470","China Diabetes Registry by Metabolic Management Center","China Diabetes Registry - a Prospective Cohort Study of Patients With Diabetes in National Metabolic Management Centers in China","CDR-MMC","Main Inclusion Criteria:\n\n* Age ≥ 18 years old\n* Diagnosis of diabetes mellitus based on self-reported history of diagnosed diabetes by clinicians or in line with the current domestic diagnostic criteria for diabetes\n* Gender: males and females\n* Provide written informed consent\n* Satisfactory compliance\n\nMain Exclusion Criteria:\n\n* Patients with significantly reduced life expectancy (less than 5 years)\n* With Drug abuse\n* With AIDS or syphilis or infectious diseases such as viral hepatitis or tuberculosis in active phase at enrollment","18 Years",{"count":57,"type":22},1000000,"OBSERVATIONAL","Epidemiologic studies have revealed a tremendous increase in the prevalence of diabetes and related mortality worldwide. In order to meet all the challenges in the treatment of metabolic diseases in China, the National Metabolic Management Center (MMC) was founded in 2016. The objective of the MMC is to launch a new metabolic disease management model based on the Internet health information platform. It allows the application and evaluation of diabetes treatment strategies at these centers. The proprietary electronic medical database in the MMC will help the dynamic big-data analysis in diabetes epidemiology, prevention, diagnosis, and treatment. It will also provide prospective data support including economic evaluation in management of chronic diseases for the Healthy China 2030 strategy.\n\nObjective\n\n1. The purpose of the present study is to establish a multi-center nationwide prospective database of diabetes patients in MMCs, including clinical data, biological samples library so as to explore the epidemiology, genetics, new biomarkers, risk factors, and prognostic methods related to diabetes and its complications, as well as other metabolic diseases.\n2. To collect cross-sectional data from patients seen and treated at each MMC centers so as to evaluate: the current status of care of patients with diabetes and its related complications, as well as other risk factors treatment strategies at these centers. Patients'costs and quality of life (QoL) will also be evaluated.\n3. To collect the prospective data of patients treated at each MMC centers in order to evaluate the strategies for the achievement of treatment goals, changes in management, control of risk factors, incidence and progression of all-diabetes related clinical endpoints (including mortality), behavioral changes, psychological well being as well as costs and QoL.",[61,62,63,64,65,66],"Type 2 Diabetes Mellitus","Type1 Diabetes Mellitus","Monogenetic Diabetes","Pancreatogenic Diabetes","Drug-Induced Diabetes Mellitus","Other Forms of Diabetes Mellitus","RECRUITING","2024-12-02",{"date":70,"type":38},"2024-12-05",{"date":72,"type":38},"2017-05-31",{"date":74,"type":22},"2039-05-31",{"name":44,"class":45},""]