[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hacettepe University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":649},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,151,0,25,[9,42,70,92,120,148,172,194,223,242,276,307,332,360,387,414,443,468,498,520,539,558,581,599,623],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100652209","turkish-validation-of-the-hoos-12-100652209",false,"NCT07770971","Turkish Validation of the HOOS-12","Turkish Cross-cultural Adaptation, Validity, Reliability, and Responsiveness of the Hip Disability and Osteoarthritis Outcome Score-12 (HOOS-12) in Patients With Hip Osteoarthritis","Inclusion Criteria:\n\n* Age 18 years or older.\n* Native Turkish speaker or able to read and understand Turkish fluently.\n* Diagnosed with primary hip osteoarthritis based on clinical and radiographic evaluation.\n* Scheduled to undergo primary total hip arthroplasty.\n* Able to complete the study questionnaires independently or with standardized assistance.\n* Clinically stable during the test-retest period.\n* Willing to participate in the study and provide written informed consent.\n\nExclusion Criteria:\n\n* Previous total hip arthroplasty on the affected side.\n* Scheduled for revision hip arthroplasty.\n* Hip arthroplasty indicated for conditions other than primary hip osteoarthritis, including hip fracture, inflammatory arthritis, avascular necrosis, congenital hip disorders, or malignancy.\n* History of major lower-extremity surgery within the previous six months.\n* Neurological or neuromuscular disorders that may substantially affect mobility or lower-extremity function.\n* Severe cognitive impairment, psychiatric disorder, or communication difficulty that prevents reliable questionnaire completion.\n* Severe visual or hearing impairment that prevents completion of the assessment procedures.\n* Presence of another acute musculoskeletal condition that substantially affects pain or physical function.\n* Any therapeutic intervention, significant change in medication, acute clinical deterioration, or surgery occurring between the baseline and test-retest assessments.\n* Incomplete questionnaire data or inability to complete the planned follow-up assessments.","ALL","18 Years",{"count":20,"type":21},150,"ESTIMATED","OBSERVATIONAL","The Hip Disability and Osteoarthritis Outcome Score-12 (HOOS-12) is a short patient-reported outcome measure developed to assess pain, function, and hip-related quality of life in individuals with hip osteoarthritis. Although widely used internationally, a validated Turkish version is currently unavailable. This study aims to translate and culturally adapt the HOOS-12 into Turkish and evaluate its psychometric properties, including internal consistency, test-retest reliability, construct validity, structural validity, responsiveness, and measurement error, in Turkish-speaking patients with hip osteoarthritis.",[25],"Hip Osteoarthritis",[25,27,28,29],"validity","Turkish","Reliability","NOT_YET_RECRUITING","2026-08-17",{"date":33,"type":34},"2026-08-18","ACTUAL",{"date":36,"type":21},"2026-09-01",{"date":38,"type":21},"2027-12-01",{"name":40,"class":41},"Hacettepe University","OTHER",{"id":43,"slug":44,"hasResults":12,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":65,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},"100652298","high-intensity-interval-training-for-walking-and-function-across-different-multiple-sclerosis-disability-levels-100652298","NCT07771868","High-Intensity Interval Training for Walking and Function Across Different Multiple Sclerosis Disability Levels","The Effect of High-Intensity Interval Training on Maximum Walking Distance and Functional Parameters in Patients With Multiple Sclerosis at Different Disability Levels","Inclusion Criteria:\n\n* Be between the ages of 18 and 65,\n* Have been diagnosed with MS by a treating physician,\n* Have an EDSS score between 0 and 6.5,\n* Not having experienced a relapse within the last 3 months,\n* Not having severe lower extremity contractures, severe spasticity (≥3 on the Modified Ashworth Scale), or an acute orthopedic problem that would prevent the participant from pedaling on a bicycle ergometer,\n* Having a Mini Mental State Examination score of ≥24.\n\nExclusion Criteria:\n\n* Having a severe cardiovascular, orthopedic, respiratory, or metabolic disease,\n* Having an additional neurological condition,\n* Being pregnant or suspecting pregnancy,\n* Having received a botulinum toxin injection within the last 3 months,\n* Having a COMPASS-31 total score greater than 13.6","65 Years",{"count":51,"type":21},30,"INTERVENTIONAL",[54],"NA","Multiple Sclerosis (MS) is a chronic neurological disease that can affect daily functioning, mobility, and overall quality of life. High-Intensity Interval Training (HIIT) is known to be a time-efficient exercise approach that improves exercise capacity and reduces fatigue in MS. However, current research lacks sufficient data on how HIIT affects individuals with different levels of disability.\n\nThe main purpose of this study is to evaluate the effects of a stationary bicycle-based HIIT protocol on maximum walking distance, fatigue, balance, muscle strength, endurance, gait speed, and quality of life in MS patients across three different disability levels: mild, moderate, and severe (classified according to Expanded Disability Status Scale - EDSS scores).\n\nParticipants will complete a cycle ergometer-based HIIT program. Assessments will be conducted at three time points:\n\nBefore starting the exercise program (baseline)\n\nImmediately after completing the program (post-treatment)\n\n4 weeks after the completion of the program (follow-up)\n\nTo ensure unbiased results, a triple-blind design will be used, meaning the outcome assessor, the treating physiotherapist, and the data analyst will be blinded to group assignments. The findings aim to help clinicians tailor personalized, effective HIIT protocols based on a patient's specific disability level rather than using a standardized, one-size-fits-all approach in MS rehabilitation.",[57],"MULTIPL SCLEROSİS",[59,60,61,62],"Multiple Sclerosis","High-Intensity Interval Training","Cycle Ergometer","Expanded Disability Status Scale","2026-08-14",{"date":33,"type":34},{"date":31,"type":21},{"date":67,"type":21},"2028-01-31",{"name":40,"class":41},1,{"id":71,"slug":72,"hasResults":12,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":52,"phases":79,"briefSummary":80,"conditions":81,"keywords":82,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":86,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":69},"100603523","motor-imagery-and-action-observation-for-gait-function-in-ms-100603523","NCT07137624","Motor Imagery and Action Observation for Gait Function in MS","Effects of Motor Imagery and Action Observation on Gait Initiation and Spatiotemporal Gait Parameters in Multiple Sclerosis","Inclusion Criteria:\n\n* A confirmed diagnosis of multiple sclerosis (MS) by a neurologist\n* No history of relapse within the past 3 months and not currently experiencing a relapse\n* A score of 24 or higher on the standardized Mini Mental State Examination\n\nExclusion Criteria:\n\n* Presence of serious health conditions affecting the muscles, heart, lungs, or metabolism that could interfere with participation\n* History of other neurological disorders, head injury, or chronic psychiatric conditions\n* Chronic pain lasting longer than six months\n* Significant muscle stiffness in the legs that may affect EMG recordings\n* Hearing difficulties\n* Vision problems as determined by the Snellen visual acuity test",{"count":78,"type":21},20,[54],"This study will investigate whether mentally simulating walking movements while watching others walk can improve walking performance in individuals with Multiple Sclerosis (MS). Participants will be divided into two groups: one group will watch walking videos and imagine themselves walking, while the other group will watch nature scenes. The study will measure muscle activity and walking patterns to assess the effects. The results may help support the use of mental practice techniques to improve mobility in people with MS.",[59],[83,84],"Motor imagery","Action Observation","RECRUITING",{"date":31,"type":34},{"date":88,"type":34},"2026-01-03",{"date":90,"type":21},"2026-09",{"name":40,"class":41},{"id":93,"slug":94,"hasResults":12,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":12,"sex":17,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":52,"phases":103,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":117,"leadSponsor":119,"locationsCount":69},"100650692","immediate-effects-of-kinesio-taping-on-thoracic-outlet-syndrome-100650692","NCT07750184","Immediate Effects of Kinesio Taping on Thoracic Outlet Syndrome","Immediate Effects of Kinesio Taping on Symptoms, Grip Strength, and Hand Dexterity in Patients With Thoracic Outlet Syndrome","Inclusion Criteria:\n\n* Clinical diagnosis of Thoracic Outlet Syndrome (TOS) confirmed by a thoracic surgeon.\n* Presence of symptoms consistent with TOS.\n* Ability to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* History of fracture or surgery involving the cervical spine, shoulder, elbow, wrist, or hand that could affect upper-extremity function.\n* Neurological disorders affecting upper-extremity function (e.g., stroke, multiple sclerosis, peripheral neuropathy unrelated to TOS).\n* Other upper-extremity musculoskeletal disorders that may influence grip strength or hand dexterity (e.g., carpal tunnel syndrome, trigger finger, thumb carpometacarpal osteoarthritis).\n* Skin lesions, allergy to adhesive tape, or any dermatological condition preventing tape application.\n* Pregnancy.\n* Inability to perform the assessment procedures.","20 Years","45 Years",{"count":102,"type":21},32,[54],"The goal of this clinical trial is to evaluate the immediate effects of Kinesio Taping compared with sham taping in adults with Thoracic Outlet Syndrome (TOS). The study aims to determine whether a single application of Kinesio Taping provides greater improvements in symptom severity, grip strength, and hand dexterity than sham taping. The main questions it aims to answer are:\n\nDoes a single application of Kinesio Taping reduce symptom severity and improve tolerance to the Roos test compared with sham taping? Does a single application of Kinesio Taping improve grip strength and hand dexterity compared with sham taping? Researchers will compare participants receiving Kinesio Taping with those receiving sham taping to determine whether the observed effects are attributable to the therapeutic application of Kinesio Taping rather than nonspecific or placebo effects.\n\nParticipants will:\n\n* undergo baseline assessments of symptom severity during the Roos test, Roos test completion time, grip strength, and hand dexterity;\n* be randomly assigned to receive either Kinesio Taping or sham taping;\n* undergo immediate post-intervention assessments using the same outcome measures.",[106],"Thoracic Outlet Syndrome",[108,109,110,111,112],"thoracic outlet syndrome","taping","strength","pain","hand dexterity","2026-08-06",{"date":115,"type":34},"2026-08-10",{"date":36,"type":21},{"date":118,"type":21},"2026-12",{"name":40,"class":41},{"id":121,"slug":122,"hasResults":12,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":12,"sex":17,"minAge":127,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":131,"conditions":132,"keywords":134,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":69},"100651210","brain-heart-axis-in-type-2-diabetes-mellitus-100651210","NCT07757308","Brain-Heart Axis in Type 2 Diabetes Mellitus","Effects of Metabolic Dysfunction on Functional Capacity and Mental Health Through the Brain-Heart Axis in Type 2 Diabetes Mellitus: A Cross-Sectional Study Based on Electroencephalography and Heart Rate Variability","Inclusion Criteria:\n\n* Adults aged 40 to 75 years.\n* Confirmed diagnosis of Type 2 Diabetes Mellitus (T2DM).\n* Able to understand the study procedures and provide written informed consent.\n* Able to complete all planned clinical, neurophysiological, cognitive, and functional assessments.\n\nExclusion Criteria:\n\n* Diagnosis of neurological, psychiatric, orthopedic, or other systemic diseases that may influence study outcomes.\n* Cognitive or psychological impairment preventing completion of study assessments.\n* History of recent surgery or acute medical condition affecting participation.\n* Inability or unwillingness to provide written informed consent.\n* Inability to complete the assessment protocol.","40 Years","75 Years",{"count":130,"type":21},46,"Type 2 Diabetes Mellitus (T2DM) is associated with chronic hyperglycemia and metabolic disturbances that affect not only glucose metabolism but also the central nervous system, autonomic nervous system, and cardiovascular function. Growing evidence suggests that individuals with T2DM are at increased risk of cognitive impairment, autonomic dysfunction, reduced functional capacity, and psychological distress. However, the interactions among metabolic status, brain activity, cardiac autonomic regulation, functional performance, and mental health have not been comprehensively investigated within a single study.\n\nThis cross-sectional study aims to investigate the relationships between metabolic abnormalities and brain-heart axis function in adults with T2DM. Approximately 50 participants aged 40-65 years with a confirmed diagnosis of T2DM will undergo comprehensive assessments, including resting electroencephalography (EEG), heart rate variability (HRV), functional capacity tests (1-Minute Sit-to-Stand Test and 6-Minute Walk Test), cognitive function using the Montreal Cognitive Assessment (MoCA), physical activity using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and psychological status using the Depression Anxiety Stress Scale (DASS-21). Clinical and metabolic variables, including HbA1c, fasting blood glucose, lipid profile, and inflammatory markers, will also be collected from medical records.\n\nThe primary objective is to determine whether metabolic disturbances are associated with alterations in EEG-derived brain activity and HRV-derived autonomic function and whether these changes are related to cognitive performance, functional capacity, physical activity, and psychological well-being. Correlation analyses, path analysis, and structural equation modeling will be used to explore direct and indirect relationships among these variables. The findings are expected to improve understanding of the brain-heart axis in T2DM and provide evidence for multidimensional assessment strategies to support early detection of neurocardiac dysfunction and optimize rehabilitation approaches.",[133],"Type 2 Diabetes Mellitus (T2DM)",[135,136,137,138,139],"Type 2 Diabetes Mellitus","Electroencephalography (EEG)","Heart Rate Variability","Brain-Heart Axis","Functional Capacity","2026-08-05",{"date":142,"type":34},"2026-08-11",{"date":144,"type":34},"2026-06-25",{"date":146,"type":21},"2026-09-30",{"name":40,"class":41},{"id":149,"slug":150,"hasResults":12,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":4,"eligibilityCriteria":154,"healthyVolunteers":155,"sex":17,"minAge":127,"maxAge":128,"enrollmentInfo":156,"targetDuration":4,"studyType":52,"phases":158,"briefSummary":159,"conditions":160,"keywords":162,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":69},"100650885","unilateral-and-bilateral-resistance-training-in-hypertension-100650885","NCT07751445","Unilateral and Bilateral Resistance Training in Hypertension","Comparison of the Effects of Unilateral and Bilateral Resistance Training on Heart Rate Variability, Muscle Strength, and Functional Capacity in Individuals With Hypertension: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 40 to 75 years.\n* Physician-confirmed diagnosis of hypertension.\n* Medically stable and able to safely participate in a supervised resistance training program.\n* Able to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Presence of cardiovascular diseases other than hypertension.\n* Neurological disorders.\n* Psychiatric disorders.\n* Orthopedic conditions limiting participation in resistance exercise.\n* Any other systemic disease that may interfere with study participation.\n* Cognitive impairment or psychological conditions preventing completion of the assessments.\n* History of recent surgery or medical conditions contraindicating exercise.\n* Inability or unwillingness to comply with the study protocol.",true,{"count":157,"type":21},54,[54],"Hypertension is associated with autonomic nervous system dysfunction, reduced muscle strength, and impaired functional capacity, all of which contribute to increased cardiovascular risk and decreased quality of life. Resistance training is recommended as a non-pharmacological intervention for hypertension; however, it remains unclear whether unilateral and bilateral resistance training produce different physiological adaptations, particularly regarding cardiac autonomic function.\n\nThis randomized controlled trial aims to compare the effects of unilateral and bilateral resistance training on heart rate variability (HRV), muscle strength, and functional capacity in adults with hypertension. Eligible participants aged 40-75 years with a confirmed diagnosis of hypertension will be randomly allocated to one of three groups: a unilateral resistance training group, a bilateral resistance training group, or a control group. Randomization will be performed using a computer-generated block randomization procedure with sex stratification to ensure balanced group allocation.\n\nParticipants in the two intervention groups will complete a supervised 12-week resistance training program, performed twice weekly at an intensity of 60-70% of one-repetition maximum (1RM). The unilateral training group will perform exercises using one limb at a time, whereas the bilateral training group will perform the same exercises simultaneously with both limbs. The control group will receive no structured exercise intervention during the study period but will receive general information regarding the benefits of physical activity.\n\nAssessments will be conducted at baseline and after the 12-week intervention. The primary outcome will be heart rate variability measured using a Polar H10 heart rate sensor and Elite HRV software. Secondary outcomes will include peripheral muscle strength assessed by one-repetition maximum testing, functional capacity assessed using the Six-Minute Walk Test and the Glittre Activities of Daily Living Test, and blood pressure measured using a sphygmomanometer.\n\nThe findings of this study are expected to provide evidence regarding the optimal resistance training strategy for improving autonomic function and physical performance in individuals with hypertension, thereby supporting the development of safer and more individualized exercise prescriptions.",[161],"Hypertension",[161,163,137,164,139],"Resistance Training","Muscle Strength",{"date":166,"type":34},"2026-08-07",{"date":168,"type":34},"2026-06-22",{"date":170,"type":21},"2026-10-01",{"name":40,"class":41},{"id":173,"slug":174,"hasResults":12,"nctId":175,"briefTitle":176,"officialTitle":177,"acronym":4,"eligibilityCriteria":178,"healthyVolunteers":155,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":179,"targetDuration":4,"studyType":52,"phases":180,"briefSummary":181,"conditions":182,"keywords":184,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":188,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":69},"100650697","comparison-of-the-effects-of-long-term-rowing-training-in-professional-rowers-100650697","NCT07752927","Comparison of the Effects of Long-Term Rowing Training in Professional Rowers","Comparison of the Effects of Long-Term Rowing Training on Aerobic Capacity, Physical Fitness, and Psychological Parameters in Novice Individuals and Professional Rowers","Inclusion Criteria:\n\nAdults aged 18 to 65 years. Able and willing to provide written informed consent. Medically able to participate in an 8-week rowing training program. For the novice rowing group: no previous structured rowing training experience. For the professional rowing group: actively competing or regularly training as a rower.\n\nFor the control group: healthy individuals not participating in structured rowing training during the study period.\n\nExclusion Criteria:\n\nHistory of cardiovascular, neurological, orthopedic, psychiatric, or other systemic diseases that may interfere with study participation.\n\nCognitive or psychological conditions that prevent completion of the study assessments.\n\nHistory of recent surgery or any medical condition limiting exercise participation.\n\nPregnancy. Inability or unwillingness to complete the intervention or outcome assessments. Participation in another structured exercise intervention during the study period.",{"count":157,"type":21},[54],"This study aims to compare the effects of long-term rowing training on aerobic capacity, physical fitness, heart rate variability, and psychological performance in novice rowers, professional rowers, and healthy controls. Approximately 60 adults aged 18-65 years will be enrolled and allocated into three groups: novice rowers, professional rowers, and a non-exercising control group. Participants in the rowing groups will complete an 8-week supervised rowing ergometer training program (twice weekly), while the control group will maintain their usual daily activities without structured exercise. Assessments will be performed before and after the intervention and will include aerobic capacity (shuttle walk test, 500-m and 2000-m rowing ergometer tests), muscle strength, muscle power, muscular endurance, core stability, flexibility, agility, posture, heart rate variability, flow state, and mental toughness. The study is designed to provide a comprehensive evaluation of the physiological and psychological adaptations associated with rowing training at different levels of experience and to identify factors that distinguish novice and elite rowers.",[183],"Rowing",[183,185,186,137,187],"Aerobic Capacity","Physical Fitness","Mental Toughness",{"date":166,"type":34},{"date":190,"type":34},"2026-06-24",{"date":192,"type":21},"2026-11-01",{"name":40,"class":41},{"id":195,"slug":196,"hasResults":12,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":12,"sex":201,"minAge":18,"maxAge":4,"enrollmentInfo":202,"targetDuration":204,"studyType":22,"phases":4,"briefSummary":205,"conditions":206,"keywords":209,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":216,"lastUpdatePostDateStruct":217,"startDateStruct":218,"completionDateStruct":219,"leadSponsor":221,"locationsCount":222},"100650839","anticipated-stigma-illness-identity-and-quality-of-life-in-male-hypogonadism-100650839","NCT07752511","Anticipated Stigma, Illness Identity, and Quality of Life in Male Hypogonadism","The Impact of Anticipated Illness Stigma and Illness Identity on Quality of Life in Men With Hypogonadism: A Comparative Study With Other Chronic Endocrine Diseases","Inclusion Criteria:\n\nCases:\n\n* Male, aged 18 years or older.\n* Biochemically confirmed hypogonadism (total testosterone \\\u003C 300 ng\u002FdL with at least one clinical symptom).\n* Regular follow-up at the endocrinology outpatient clinic.\n* Fluent in reading and understanding Turkish.\n* Signed informed consent.\n\nControls:\n\n* Male, aged 18 years or older.\n* Diagnosed with diabetes, hypertension, or hypothyroidism under regular endocrinology follow-up.\n* Total testosterone ≥ 300 ng\u002FdL.\n* Age-matched to a participant in the case group (±5 years).\n* Fluent in reading and understanding Turkish.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Active psychiatric diagnosis (e.g., active psychosis, bipolar disorder).\n* Chronic inflammatory or rheumatological diseases affecting body composition (e.g., chronic kidney disease, IBD, rheumatoid arthritis, SLE, ankylosing spondylitis).\n* Uncontrolled co-existing endocrine conditions or severe complications (e.g., HbA1c \\> 8.0%, diabetic neuropathy\u002Fnephropathy\u002Fretinopathy, non-euthyroid state).\n* Cognitive impairment or dementia precluding questionnaire completion.\n* Klinefelter syndrome.\n* Literacy limitations preventing completion of self-report measures.\n* Additional control exclusion: Diagnosis or clinical suspicion of hypogonadism.","MALE",{"count":203,"type":21},90,"1 Day","This study aims to systematically compare the levels of anticipated illness stigma and illness identity among men diagnosed with hypogonadism to those of men with other chronic endocrine conditions (e.g., diabetes mellitus, hypothyroidism, and hypertension). Furthermore, it examines whether these psychosocial variables predict quality-of-life deterioration specifically within the hypogonadism cohort.",[207,208,161],"Hypogonadism, Male","Endocrine Disease",[210,211,212,213,214,215],"Hypogonadism","Anticipated Stigma","Illness Identity","Quality of Life","Chronic Endocrine Diseases","Psychosocial Factors","2026-08-04",{"date":166,"type":34},{"date":170,"type":21},{"date":220,"type":21},"2027-10-30",{"name":40,"class":41},2,{"id":224,"slug":225,"hasResults":12,"nctId":226,"briefTitle":227,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":229,"targetDuration":4,"studyType":52,"phases":230,"briefSummary":231,"conditions":232,"keywords":4,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":235,"lastUpdatePostDateStruct":236,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":69},"100538836","effectiveness-of-conservative-interventions-in-the-treatment-of-trigger-finger-100538836","NCT06296017","Effectiveness of Conservative Interventions in the Treatment of Trigger Finger","Inclusion Criteria:\n\n* Volunteering\n* Being between the ages of 18-65\n* Being diagnosed with stage 1 or stage 2 (according to the Froimson classification) trigger finger\n* Having the language and cognitive skills to answer the questionnaires used in the evaluation\n\nExclusion Criteria:\n\n* Being pregnant\n* Having an inflammatory disorder\n* Having had surgery on the hand\u002Fwrist\n* Having a neurological disease\n* NSAIDs, painkillers, etc. being on medication\n* De Quervain's tenosynovitis, carpal tunnel syndrome",{"count":157,"type":21},[54],"There is no study in the literature comparing the effectiveness of ESWT and splint therapy, which are the most commonly used approaches in the treatment of Trigger Finger (TF). The aim in this study is to investigate the effectiveness of ESWT and splint therapy used in the treatment of TF.",[233,234],"Trigger Finger","Stenosing Tenosynovitis","2026-08-03",{"date":140,"type":34},{"date":238,"type":34},"2025-10-02",{"date":240,"type":21},"2027-08",{"name":40,"class":41},{"id":243,"slug":244,"hasResults":12,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":12,"sex":249,"minAge":99,"maxAge":127,"enrollmentInfo":250,"targetDuration":4,"studyType":52,"phases":252,"briefSummary":253,"conditions":254,"keywords":258,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":69},"100623999","the-effect-of-fermented-grape-juice-consumption-on-fibromyalgia-patients-100623999","NCT07403929","The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients","Determination of the Effect of Fermented Grape Juice Consumption on Oxidative Stress and Inflammation Biomarkers and SIRT-1 Levels in Fibromyalgia Patients","Inclusion Criteria:\n\n* Female, 20-40 years\n* BMI 25.0-29.9 kg\u002Fm²\n* FM per 2016 ACR criteria; abdominal pain\u002Fcramp per SSS sub-item\n* MEDAS ≤5 at screening.\n* Willing to maintain habitual activity and comply with assigned intervention; able to provide informed consent.\n\nExclusion Criteria:\n\n* Age \\\u003C20 or \\>40\n* BMI ≤24.99 or ≥30.0 kg\u002Fm²\n* Professional athletes; night-shift workers\n* Food allergies; acute infection; antibiotic use within past month or during intervention.\n* Use (past 3 months) of dietary supplements; recent weight-loss or special diets (e.g., ketogenic).\n* Pregnancy\u002Flactation; menopause.\n* Major hepatic\u002Frenal\u002Fcardiac\u002Fimmune disease; chronic GI diseases; diabetes; CNS disorders; cancer; thyroid disease; severe pulmonary disease. Inflammatory arthritis\u002Fautoimmune disease impacting weight; medications including corticosteroids, estrogens, analgesics\u002Fanti-inflammatories, anti-diabetic or lipid-lowering drugs.\n* Severe psychiatric illness\u002Fsubstance use; heavy alcohol\u002Fsmoking.\n* High recent intake of grape juice\u002Fmolasses; excess tea\u002Fcoffee (≥7 cups\u002Fday).\n* Adherence \\\u003C80% to beverage or MNT during run-in\u002Fscreening.","FEMALE",{"count":251,"type":21},45,[54],"The goal of this clinical trial is to learn if a traditional grape-based fermented drink called hardaliye helps treat fibromyalgia in adult women. We will also learn whether adding hardaliye to a personalized nutrition plan works better than using either one alone.\n\nThe main questions are:\n\nDoes diet + hardaliye improve antioxidant status and lower oxidative stress more than diet only or hardaliye only? Does diet + hardaliye lower inflammation (TNF-α, IL-6, hs-CRP) and raise SIRT1 levels? Do these changes relate to less pain and better symptoms (fibromyalgia impact, gut symptoms, sleep, mood)? Are there benefits for weight, waist size, blood pressure, and blood lipids?\n\nHow the groups are compared:\n\nResearchers will compare three groups for 8 weeks:\n\nDiet + Hardaliye (personalized medical nutrition plan + one 200 mL bottle of hardaliye daily) Diet only (personalized medical nutrition plan) Hardaliye only (usual diet + one 200 mL bottle of hardaliye daily)\n\nParticipants will:\n\nDrink one 200 mL bottle of hardaliye each day if assigned to Diet + Hardaliye or Hardaliye only Follow a personalized nutrition plan if assigned to Diet + Hardaliye or Diet only Visit the clinic at the start and end of the study, with brief check-ins around weeks 2, 4, and 6 Give blood samples before and after the 8-week period Complete short questionnaires on pain, fibromyalgia impact, gut symptoms, sleep, and mood Keep simple logs of daily drink intake and diet plan adherence, and report any side effects\n\nWho can join:\n\nAdult women (20-40 years) with doctor-diagnosed fibromyalgia and BMI 25.0-29.9 kg\u002Fm² who meet the study's health and medication criteria.",[255,256,257],"Fibromyalgia","Fibromyalgia (FM)","Fibromyalgia Syndrome, Primary",[259,260,111,261,262,263,264,265,266,267],"fibromyalgia","chronic pain","inflammation","oxidative stress","sirtuin-1","SIRT1","gut microbiota","phytochemicals","nutrition","2026-07-30",{"date":270,"type":34},"2026-07-31",{"date":272,"type":34},"2026-03-15",{"date":274,"type":21},"2027-02-15",{"name":40,"class":41},{"id":277,"slug":278,"hasResults":12,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":282,"eligibilityCriteria":283,"healthyVolunteers":155,"sex":249,"minAge":18,"maxAge":284,"enrollmentInfo":285,"targetDuration":4,"studyType":52,"phases":286,"briefSummary":287,"conditions":288,"keywords":292,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":300,"lastUpdatePostDateStruct":301,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":4},"100649522","the-effect-of-individual-sodium-citrate-consumption-on-repeated-sprint-performance-in-female-soccer-players-100649522","NCT07737327","The Effect of Individual Sodium Citrate Consumption on Repeated Sprint Performance in Female Soccer Players","The Acute Effects of Individually Timed Sodium Citrate Ingestion on Repeated Sprint Performance in Professional Female Soccer Players: A Randomized, Double-Blind, Placebo-Controlled Crossover Study","ITSCORE-F","Inclusion Criteria:\n\n* Female professional soccer players competing in the Turkish Women's Third League\n* Age between 18-25 years\n* Active training status (minimum 3 sessions per week)\n* Regular menstrual cycles\n* Both experimental trials scheduled in the same phase of the menstrual cycle, outside of menstruation\n* No use of nutritional supplements in the 4 weeks prior to the study\n* Willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Use of oral contraceptives\n* Irregular menstrual cycle\n* History of gastrointestinal disorders\n* Any musculoskeletal injury preventing maximal sprint performance\n* Smoking\n* Use of any medication that may affect acid-base balance\n* Pregnancy","25 Years",{"count":78,"type":21},[54],"The aim of this research is to determine whether sodium citrate supplementation, taken at the best individual time, would improve repeated sprint performance in professional female soccer players.\n\nThe main questions it aims to answer are:\n\n1. Does sodium citrate improve sprint times, peak power, minimum power, and mean power during repeated sprints?\n2. Does sodium citrate lower fatigue index (the drop in power across sprints) during repeated sprint exercise?\n3. Does sodium citrate change blood bicarbonate, pH, and lactate levels before and after exercise?\n4. Does sodium citrate affect how hard exercise feels (perceived exertion)?",[289,290,291],"Exercise-Induced Fatigue","Athletic Performance","Soccer",[293,294,295,296,291,297,298,299],"Sodium citrate","Buffering agent","Repeated sprint performance","Female athletes","Anaerobic performance","Blood bicarbonate","Individualized timing","2026-07-27",{"date":268,"type":34},{"date":303,"type":21},"2026-08-20",{"date":305,"type":21},"2027-02-01",{"name":40,"class":41},{"id":308,"slug":309,"hasResults":12,"nctId":310,"briefTitle":311,"officialTitle":311,"acronym":4,"eligibilityCriteria":312,"healthyVolunteers":155,"sex":249,"minAge":18,"maxAge":4,"enrollmentInfo":313,"targetDuration":4,"studyType":52,"phases":315,"briefSummary":316,"conditions":317,"keywords":320,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":325,"lastUpdatePostDateStruct":326,"startDateStruct":328,"completionDateStruct":330,"leadSponsor":331,"locationsCount":69},"100649089","the-effect-of-a-virtual-reality-based-mindfulness-intervention-on-anxiety-comfort-sleep-and-fatigue-in-breast-cancer-patients-undergoing-chemotherapy-100649089","NCT07731477","The Effect of a Virtual Reality-Based Mindfulness Intervention on Anxiety, Comfort, Sleep, and Fatigue in Breast Cancer Patients Undergoing Chemotherapy","Inclusion Criteria:\n\nNewly diagnosed with breast cancer, Female and aged 18 years or older, Diagnosed with stage II or III breast cancer, Scheduled to receive chemotherapy for breast cancer for the first time in the adjuvant or neoadjuvant setting, using either the CA regimen \\[C: cyclophosphamide; A: doxorubicin (Adriamycin)\\] or the TC regimen \\[T: docetaxel; C: cyclophosphamide\\], with or without paclitaxel, trastuzumab, docetaxel, or carboplatin, Scheduled to receive chemotherapy but have not yet started treatment, Have a Beck Depression Inventory (BDI) score of ≤30, have no physician-diagnosed psychiatric disorder according to the DSM-5 diagnostic criteria, and are not receiving treatment for a psychiatric disorder (Appendix 8), Have completed at least primary school education, Voluntarily agree to participate in the study.\n\nExclusion Criteria:\n\nPresence of metastasis, History of seizures, Presence of vertigo, Presence of motion sickness with a tendency toward nausea and vomiting, Communication difficulties, including hearing, visual, or speech impairments, Unwillingness to participate in the study. Withdrawal Criteria\n\nParticipants will be withdrawn from the study if:\n\nThey discontinue the treatment protocol at any stage, Their treatment protocol is changed, They no longer wish to continue participating in the study.",{"count":314,"type":21},50,[54],"Breast cancer is a public health issue with a high incidence among women worldwide, and its prevalence continues to increase each year. A breast cancer diagnosis brings significant physical, emotional, social, economic, and occupational changes. Chemotherapy, one of the most commonly used treatment modalities in cancer therapy, causes various physical and emotional symptoms while treating the disease. However, it is well known that these symptoms induced by chemotherapy can be prevented or alleviated through effective treatment and nursing interventions.\n\nRecently, virtual reality (VR) and mindfulness-based interventions have been reported as effective tools and methods for managing the physical and psychological symptoms experienced by cancer patients.\n\nThe present study aims to evaluate the effect of a VR-integrated mindfulness-based intervention on anxiety, comfort, sleep, and fatigue levels among women newly diagnosed with breast cancer, both before and during chemotherapy treatment. The study is designed as a randomized controlled trial (RCT).\n\nThe study population will consist of individuals diagnosed with breast cancer at the Oncology Outpatient Clinic of Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between May 2025 and December 2026. The study sample will include female breast cancer patients who are scheduled to receive adjuvant chemotherapy, meet the inclusion criteria, and volunteer to participate in the study.\n\nAccording to the power analysis (with a 30% additional error margin), a total of 50 participants will be included - 25 in the intervention group and 25 in the control group.\n\nThe data will be collected using the following instruments: Patient Information Form, Beck Depression Inventory, Cancer Fatigue Scale, General Comfort Questionnaire-Short Form, State Anxiety Inventory, Jenkins Sleep Scale, and the Mindfulness-Based Self-Efficacy Scale.\n\nIt is expected that, as a result of this study, compared to the control group, participants in the intervention group who receive the VR-Mindfulness intervention during breast cancer treatment will demonstrate reduced levels of fatigue and anxiety and improved comfort and sleep quality.",[318,319],"Breast Cancer","Chemotherapy",[321,322,323,324],"Breast cancer","chemotherapy","Mindfulness","Virtual Reality","2026-07-22",{"date":327,"type":34},"2026-07-28",{"date":329,"type":34},"2025-10-01",{"date":146,"type":21},{"name":40,"class":41},{"id":333,"slug":334,"hasResults":12,"nctId":335,"briefTitle":336,"officialTitle":337,"acronym":4,"eligibilityCriteria":338,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":339,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":341,"conditions":342,"keywords":346,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":69},"100638980","ultrasound-measurement-of-skin-to-epiglottis-distance-for-prediction-of-difficult-airway-in-adult-patients-100638980","NCT07609147","Ultrasound Measurement of Skin-to-Epiglottis Distance for Prediction of Difficult Airway in Adult Patients","Ultrasound Measurement of Skin to Epiglottis Distance for Prediction of Difficult Airway in Adult Patients","Inclusion Criteria:\n\n* ≥18 yaş elective surgery\n\nExclusion Criteria:\n\n* emergency surgery\n* head and neck surgery\n* pregnant patients",{"count":340,"type":21},300,"This prospective observational study aims to evaluate the predictive value of ultrasound-measured skin to epiglottis distance for difficult airway in adult patients undergoing elective or emergency procedures requiring airway management. The correlation between ultrasound measurements and standard airway assessment parameters will be analyzed.",[343,344,345],"Tracheal Intubation, Elective Surgery","Tracheal Diamater Measurement","Ultrasound Evaluation of Airway",[347,348,349,350,351],"ultrasound","airway","epiglottis","Skin-to-Epiglottis Distance","Difficult Airway Prediction","2026-07-16",{"date":354,"type":34},"2026-07-17",{"date":356,"type":21},"2026-07-01",{"date":358,"type":21},"2026-12-04",{"name":40,"class":41},{"id":361,"slug":362,"hasResults":12,"nctId":363,"briefTitle":364,"officialTitle":365,"acronym":4,"eligibilityCriteria":366,"healthyVolunteers":155,"sex":17,"minAge":18,"maxAge":284,"enrollmentInfo":367,"targetDuration":4,"studyType":52,"phases":369,"briefSummary":370,"conditions":371,"keywords":374,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":380,"startDateStruct":382,"completionDateStruct":384,"leadSponsor":386,"locationsCount":69},"100646699","effects-of-basic-body-awareness-therapy-on-gait-and-plantar-pressure-in-healthy-young-adults-100646699","NCT07688785","Effects of Basic Body Awareness Therapy on Gait and Plantar Pressure in Healthy Young Adults","Effects of Basic Body Awareness Therapy on Spatiotemporal Gait Characteristics and Plantar Pressure Distribution in Healthy Young Adults","Inclusion Criteria:\n\n* Aged 18 to 25 years\n* Able to walk independently\n* No history of lower-extremity, spine, or balance-affecting trauma and\u002For surgery within the last 6 months\n* Not receiving regular Basic Body Awareness Therapy\n* Provides written informed consent\n\nExclusion Criteria:\n\n* History of neurological, vestibular, or rheumatological disease\n* Acute musculoskeletal injury\n* Serious visual or hearing impairment\n* Pain, deformity, or assistive device use that may affect walking performance\n* Participation in a physiotherapy program and\u002For regular exercise program within the last 6 months\n* Any condition preventing regular participation in assessment or therapy sessions",{"count":368,"type":21},33,[54],"This interventional study will evaluate the effects of Basic Body Awareness Therapy (BBAT) on gait and plantar pressure outcomes in healthy young adults. Participants aged 18 to 25 years will receive a 12-week BBAT program delivered twice weekly by a physiotherapist trained in BBAT. Outcomes will be assessed at baseline, after the 12-week intervention, and at 3-month follow-up. The primary aim is to determine changes in gait speed and other spatiotemporal gait parameters during the 10-meter walk test. Secondary aims are to examine changes in static and dynamic plantar load distribution, right-left load sharing, and regional plantar pressure parameters. The study hypothesizes that BBAT will improve gait speed, reduce right-left differences in spatiotemporal gait parameters, improve bilateral load distribution during static stance and walking, and maintain these gains at 3-month follow-up.",[372,373],"Gait","Body Awareness",[375,376,377,378],"Basic body awareness therapy","healthy young adult","Gait Analysis","plantar pressure","2026-07-14",{"date":381,"type":34},"2026-07-15",{"date":383,"type":34},"2026-06-29",{"date":385,"type":21},"2027-01-04",{"name":40,"class":41},{"id":388,"slug":389,"hasResults":12,"nctId":390,"briefTitle":391,"officialTitle":391,"acronym":4,"eligibilityCriteria":392,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":393,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":395,"conditions":396,"keywords":403,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":407,"lastUpdatePostDateStruct":408,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":413,"locationsCount":69},"100645113","the-relationship-between-lost-extremity-percentage-and-postural-control-neck-and-low-back-pain-daily-living-activities-and-reaction-time-in-individuals-with-unilateral-upper-limb-amputation-100645113","NCT07677969","The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation","Inclusion Criteria:\n\n* Adults aged 18-65 years\n* Unilateral upper limb amputation\n* Use of a myoelectric or bionic prosthesis for at least 1 year\n* Current prosthesis use for a minimum of 3 months\n\nExclusion Criteria:\n\n* Bilateral upper limb amputation\n* Additional amputation of another limb\n* Use of passive or cosmetic prosthesis\n* Presence of neurological or other significant orthopedic disorders unrelated to amputation",{"count":394,"type":21},15,"This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation. Upper limb amputation can affect posture, balance control, pain levels, daily living activities, hand function, and reaction time. However, limited research has investigated how the amount of limb loss influences these outcomes.\n\nParticipants between 18 and 65 years of age who use a myoelectric or bionic prosthesis will undergo a series of assessments. These assessments include measurements of postural control using a force platform, posture analysis, evaluation of neck and low back pain using a visual analog scale, daily living activities using a validated questionnaire, hand dexterity using the Box and Block Test, and reaction time using a visual stimulus device.\n\nThe study does not involve any intervention or treatment. All evaluations will be performed during a single assessment session. The results of this study may help improve rehabilitation planning and provide better understanding of functional changes associated with different levels of limb loss in people with upper limb amputation.",[397,398,399,400,401,402],"Upper Limb Amputation","Postural Control","Neck Pain","Low Back Pain","Daily Activities","Reaction Time",[397,398,399,404,405,406],"low back pain","Daily Living Activities","reaction time","2026-06-30",{"date":356,"type":34},{"date":410,"type":34},"2026-01-01",{"date":412,"type":21},"2026-12-01",{"name":40,"class":41},{"id":415,"slug":416,"hasResults":12,"nctId":417,"briefTitle":418,"officialTitle":419,"acronym":4,"eligibilityCriteria":420,"healthyVolunteers":12,"sex":249,"minAge":421,"maxAge":100,"enrollmentInfo":422,"targetDuration":4,"studyType":52,"phases":424,"briefSummary":425,"conditions":426,"keywords":428,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":407,"lastUpdatePostDateStruct":436,"startDateStruct":438,"completionDateStruct":440,"leadSponsor":442,"locationsCount":69},"100561052","impact-of-a-web-based-mind-body-awareness-program-on-women-undergoing-infertility-treatment-100561052","NCT06585137","Impact of a Web-Based Mind-Body Awareness Program on Women Undergoing Infertility Treatment","The Effect of a Web-Based Mind-Body Awareness Program Based on Meleis Transition Theory on Women Receiving Infertility Treatment: A Randomized Controlled Study","Inclusion Criteria:\n\n* Volunteering to participate in research\n* Being diagnosed with primary infertility\n* Starting the infertility treatment process\n* Having attempted IVF at most twice before\n* Being able to speak and understand Turkish\n* Being at least a primary school graduate\n* Not taking part in any psychological or social support group.\n* Not having completed or currently participating in any mind\u002Fbody program for fertility.\n\nExclusion Criteria:\n\n* Women applying for frozen embryo transfer without ovarian stimulation\n* Being diagnosed with secondary infertility\n* Having a diagnosis of a chronic disease\n* Having communication problems (vision, hearing)","23 Years",{"count":423,"type":21},78,[54],"The goal of this two-group parallel randomized controlled study is to determine the effect of a web-based mind-body-based awareness program based on Meleis Transition Theory on fertility awareness and readiness levels in women receiving infertility treatment.",[427],"Infertility, Female",[429,430,431,432,433,434,435],"Nursing","Infertility","Nursing Theory","Fertility","Awareness","Meleis","Fertility readiness",{"date":437,"type":34},"2026-07-02",{"date":439,"type":21},"2026-07-10",{"date":441,"type":21},"2026-11-22",{"name":40,"class":41},{"id":444,"slug":445,"hasResults":12,"nctId":446,"briefTitle":447,"officialTitle":448,"acronym":449,"eligibilityCriteria":450,"healthyVolunteers":155,"sex":17,"minAge":18,"maxAge":127,"enrollmentInfo":451,"targetDuration":4,"studyType":52,"phases":453,"briefSummary":454,"conditions":455,"keywords":458,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":462,"lastUpdatePostDateStruct":463,"startDateStruct":464,"completionDateStruct":465,"leadSponsor":467,"locationsCount":69},"100645350","effects-of-a-12-week-t10-exercise-program-on-shooting-performance-upper-extremity-function-balance-and-reaction-time-in-competitive-air-pistol-athletes-100645350","NCT07681427","Effects of a 12-week T10 Exercise Program on Shooting Performance, Upper Extremity Function, Balance and Reaction Time in Competitive Air Pistol Athletes","The Effects of a 12-Week T10 Exercise Program on Shooting Performance, Upper Extremity Function, Balance, and Reaction Time in Air Pistol Athletes: A Randomized Controlled Trial","Air pistol T10","Inclusion Criteria:\n\n* Age between 18 and 40 years.\n* Competitive air pistol athletes with at least 2 years of regular shooting experience.\n* Participating in shooting training for at least 6 hours per week.\n* Being in the preseason training period.\n* Willing to participate and able to provide written informed consent.\n\nExclusion Criteria:\n\n* Current upper extremity musculoskeletal injury or pain.\n* History of upper extremity orthopedic surgery.\n* Neurological or cognitive disorders affecting participation.\n* Visual or hearing impairments that may interfere with testing or shooting performance.\n* Inflammatory joint disease involving the lower extremities.\n* History of lower extremity orthopedic surgery or musculoskeletal deformity affecting performance.\n* Rheumatologic, metabolic, or cardiovascular disease.\n* Body mass index (BMI) \\>30 kg\u002Fm².\n* Current use of psychiatric medication.\n* Failure to attend two consecutive intervention sessions during the study period.",{"count":452,"type":21},24,[54],"Air pistol shooting requires a high level of postural stability, upper extremity neuromuscular control, and concentration to achieve optimal performance. Prolonged maintenance of the shooting position may lead to shoulder muscle fatigue, reduced joint stability, and impaired shooting accuracy. Although sport-specific exercise programs have been recommended to improve physical performance in shooters, the effectiveness of the T10 exercise program has not yet been investigated in this population. This randomized controlled trial aims to evaluate the effects of a 12-week T10 exercise program, in addition to routine training, on shooting performance in competitive air pistol athletes. Secondary outcomes include upper and lower extremity functional performance, balance, muscular endurance, upper extremity stability, grip strength, medicine ball throw performance, and visual and auditory reaction time. Participants will be randomly allocated to either an intervention group receiving the T10 exercise program plus routine training or a control group continuing routine training alone. Assessments will be performed at baseline and after the 12-week intervention. The findings of this study may provide evidence for the effectiveness of a sport-specific neuromuscular exercise program in enhancing shooting performance and physical function in competitive air pistol athletes.",[456,457],"Physiotherapy and Rehabilitation","Exercise",[459,460,461],"air pistol","T10 exercise","performance","2026-06-26",{"date":437,"type":34},{"date":439,"type":21},{"date":466,"type":21},"2027-12-15",{"name":40,"class":41},{"id":469,"slug":470,"hasResults":12,"nctId":471,"briefTitle":472,"officialTitle":472,"acronym":473,"eligibilityCriteria":474,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":475,"targetDuration":4,"studyType":52,"phases":477,"briefSummary":478,"conditions":479,"keywords":489,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":493,"startDateStruct":494,"completionDateStruct":495,"leadSponsor":497,"locationsCount":4},"100622941","the-effect-of-changes-in-the-frequency-of-endotracheal-tube-repositioning-in-intensive-care-units-on-the-prevention-of-oral-mucosal-pressure-injuries-100622941","NCT07390162","The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of Oral Mucosal Pressure Injuries","PreventionMMPI","Inclusion Criteria:\n\n* The study will include patients over the age of 18, receiving MV support with oral ETT, with no tissue loss\u002Fdamage in the oral mucosa at the time of admission to the ICU, who have been intubated for less than 24 hours, with an APACHE II score ≤24, and whose first-degree relatives or legal presentative have given consent for their participation in the study.",{"count":476,"type":21},230,[54],"Intensive care units (ICUs) are care centers equipped with a wide range of technological tools and devices used to provide the highest level of care to individuals whose lives are at risk, requiring a multidisciplinary team approach. Patients may require respiratory support from a ventilator to maintain breathing. In the intensive care unit, patients' breathing is maintained using a medical device called an endotracheal tube (ETT). ETTs can cause injuries due to the constant pressure they exert on the patient's mouth and lip area. Therefore, nurses must secure the ETT at specific times to different points in the mouth area (right and left sides of the mouth) to prevent these injuries. Injuries to the mucosa caused by medical equipment are defined as \"mucosal membrane pressure injuries (MMPI).\" One such injury is an injury to the mouth. Injuries occurring in the mouth are caused by the pressure of the tubes that enable the patient to breathe in and out.\n\n\"The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of Oral Mucosal Pressure Injuries\" is a doctoral thesis study; the aim of this study is to investigate the effect of differences in the time interval for changing the position of the tube in the lip region on the prevention of injuries occurring in the mouth in patients monitored with ETT in the ICU. A review of the literature revealed that there are gaps in studies conducted at the international or national level on this subject, and that there is no definitive time guideline for changing (repositioning) the tube in the lip area.\n\nThe study will include patients over the age of 18 who are being monitored with an ETT in their mouth, who did not have any injuries in the mouth area at the time of admission to the ICU, who have not had the tube in their mouth for more than 24 hours, who are in moderate to good general condition, and whose first-degree relatives or legal presentative have given permission for them to participate in the study. In the study, the follow-up and evaluation of patients will be limited to fourteen days after tube insertion. Exclusion Criteria; Differences in respiratory support, Pre-existing artificial airway, Oncological conditions, Neurological and behavioral factors, Positional constraints, Sensory\u002Fperceptual impairment, Pre-existing injury. Patients who are discharged or transferred during the fourteen-day follow-up period will be excluded from the study. According to the sample calculation for the study, a total of 230 patients (115 volunteers in the 4-hour group and 115 volunteers in the 8-hour group) will be sufficient. In the study, patients will be stratified according to their APACHE II scores. ICU nurses are not bound by any specific time for securing the ETT. Nurses positioned the tube fixation site at the right lip edge\u002Fleft lip edge\u002Fmid-lip line; however, since they were not bound by a specific time-based rule, tube care was nurse-specific. In this study, the location of tube fixation will be recorded through observation to determine the effect of tube fixation on the formation of oral injuries. This study is planned to be completed within a 24-month timeframe between May 30, 2026, and June 15, 2027.\n\nThis research is a scientific research (doctoral thesis) study. The daily tube care of volunteers is already in place, and we emphasize that this research will not affect\u002Finterfere with the treatment and follow-up of volunteers, and that volunteers will not be negatively affected by the study in any way. The principal investigator will randomly assign volunteers being monitored with ETT to groups using a computer system and will request nurses to reposition their ETTs based on the time intervals (4 hours-8 hours) within these groups. At the same time, the researcher will collect relevant clinical data that may affect pressure injuries in patients (age, gender, smoking history, body mass index, medical history, ICU admission diagnosis, SOFA, RASS and APACHE II scores, Glasgow Coma Scale, laboratory findings (C-reactive protein, white blood cell, Hemoglobin, Hematocrit, Total Protein, Albumin, pH, PO2, Blood Sugar Level), Nutritional Status (Route and Type of Nutrition, Product), Medication Support (Sedatives, Inotropes, Antibiotics, Steroids), ETT-Related Data (Number, Depth, Fixation Site, Repositioning Time), Eilers Oral Assessment Guide and Oral Care Frequency, Braden Pressure Ulcer Risk Assessment Scale and Overall Body Pressure Ulcer Presence, Reaper Oral Mucosa Pressure Injury Scale Grade data, etc.). The follow-up period in the study will be fourteen days, during which the principal investigator will record the patients' personal health data mentioned above and terminate the follow-up of patients who develop pressure injuries in the oral mucosa. Our expectation from the study is that no injuries will occur in the mouth. In the event of a possible injury, the intervention will be terminated immediately.",[480,481,482,483,484,485,486,487,488],"Mucosal Wound","Mucosal Erosion","Mucosal Irritation","Endotracheal Intubation Fixation","Endotracheal Tube Position","Repositioning","Intensive Care Units (ICUs)","Adult Patients","Pressure Ulcer Prevention",[490,486,491,485,492],"mucosal membrane pressure injury","Endotracheal intubation fixation","pressure ulcer prevention",{"date":144,"type":34},{"date":407,"type":21},{"date":496,"type":21},"2027-06-15",{"name":40,"class":41},{"id":499,"slug":500,"hasResults":12,"nctId":501,"briefTitle":502,"officialTitle":503,"acronym":4,"eligibilityCriteria":504,"healthyVolunteers":155,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":505,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":507,"conditions":508,"keywords":511,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":514,"startDateStruct":515,"completionDateStruct":517,"leadSponsor":519,"locationsCount":69},"100564598","cardiopulmonary-responses-to-6-minute-stepper-test-in-bronchiectasis-versus-healthy-controls-100564598","NCT06631261","Cardiopulmonary Responses to 6-Minute Stepper Test in Bronchiectasis Versus Healthy Controls","Comparison of Cardiopulmonary Responses to 6-Minute Stepper Test Between Individuals With Bronchiectasis and Healthy Controls","Bronchiectasis group - Inclusion criteria for the study:\n\n* Being 18 years of age and older,\n* Having a clinically stable bronchiectasis,\n* To cooperate with the tests to be performed,\n* Not having a cardiovascular disease, orthopedic or neurological problem that may affect the tests,\n* Being willing to participate in the study.\n\nBronchiectasis group - Exclusion criteria:\n\n* Being in an acute exacerbation period,\n* Having a cardiovascular, orthopedic or neurological problem that may affect the tests,\n* Not being willing to participate in the study.\n\nControl group - Inclusion criteria for the study:\n\n* Being 18 years of age and older,\n* To cooperate with the tests to be performed,\n* Not having a cardiovascular, orthopedic or neurological problem that may affect the tests,\n* Being willing to participate in the study.\n\nControl group - Exclusion criteria:\n\n\\- Individuals with any known internal disease and those who do not volunteer to participate in the study will not be included in the study.",{"count":506,"type":21},60,"Individuals with bronchiectasis exhibit productive cough and recurrent lung infections as well as reduced exercise capacity, physical activity level, and respiratory and peripheral muscle strength. 6-minute walk test (6MWT) is often used to assess exercise capacity in chronic lung diseases. 6MWT is recommended to be performed along a flat corridor, at least 30 m long, with low pedestrian traffic, on a hard surface. To overcome technical limitations during 6MWT, 6-minute stepper test (6MST) has been proposed to assess exercise capacity. Another test that provides information about exercise capacity is the 1-minute sit-to-stand test (1STS). To our knowledge, there is limited information about different exercise tests including 6MST and 1STS and cardiopulmonary responses to these tests in individuals with bronchiectasis. Therefore, this study aims to compare the responses to the 6MST between individuals with bronchiectasis and healthy controls and to investigate the relationships among 6MST, 6MWT, and 1STS responses and muscle strength.",[509,510],"Bronchiectasis Adult","Healthy Controls Group - Age and Sex-matched",[512,513],"Bronchiectasis","Exercise Capacity",{"date":144,"type":34},{"date":516,"type":34},"2024-01-18",{"date":518,"type":21},"2027-01-18",{"name":40,"class":41},{"id":521,"slug":522,"hasResults":12,"nctId":523,"briefTitle":524,"officialTitle":525,"acronym":4,"eligibilityCriteria":526,"healthyVolunteers":155,"sex":17,"minAge":127,"maxAge":4,"enrollmentInfo":527,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":529,"conditions":530,"keywords":4,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":534,"startDateStruct":535,"completionDateStruct":537,"leadSponsor":538,"locationsCount":69},"100554340","health-literacy-physical-and-cognitive-function-health-related-behaviors-and-quality-of-life-in-copd-100554340","NCT06497816","Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in COPD","An Investigation of Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in Chronic Obstructive Pulmonary Disease and Healthy Individuals","Inclusion criteria for the COPD group:\n\n* Being over 40 years old,\n* Diagnosed with COPD and being clinically stable,\n* Being able to cooperate with the tests to be performed,\n* Not having any cardiovascular disease, orthopedic or neurological problems that may affect the tests,\n* Being willing to participate in the study.\n\nExclusion criteria for the COPD group:\n\n* Being in an acute exacerbation period,\n* Having any cardiovascular disease, orthopedic or neurological problems that may affect the tests,\n* Not being willing to participate in the study.\n\nInclusion criteria for the control group:\n\n* Being willing to participate in the study and being over 40 years old\n* Not having any known disease\n\nExclusion criteria for the control group:\n\n* Not being able to cooperate with the tests to be performed\n* Not being willing to participate in the study",{"count":528,"type":21},144,"Health literacy is important for controlling disease progression and living a healthy life with illness. High health literacy is associated with higher cognitive performance and lower health-related quality of life. Physical, psychological, and social impairments are seen in chronic obstructive pulmonary disease (COPD). Studies investigating the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD are limited. Therefore, the aim of this study was to compare individuals with COPD with healthy individuals in terms of health literacy, functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living and to investigate the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD.",[531,532,533],"COPD","Health Literacy","Health-Related Behavior",{"date":144,"type":34},{"date":536,"type":34},"2024-06-15",{"date":496,"type":21},{"name":40,"class":41},{"id":540,"slug":541,"hasResults":12,"nctId":542,"briefTitle":543,"officialTitle":544,"acronym":4,"eligibilityCriteria":545,"healthyVolunteers":12,"sex":249,"minAge":127,"maxAge":49,"enrollmentInfo":546,"targetDuration":4,"studyType":52,"phases":547,"briefSummary":548,"conditions":549,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":551,"lastUpdatePostDateStruct":552,"startDateStruct":553,"completionDateStruct":555,"leadSponsor":557,"locationsCount":69},"100644784","effects-of-core-focused-exercise-training-and-kinesiology-taping-in-women-with-breast-cancer-related-lymphedema-100644784","NCT07673939","Effects of Core-Focused Exercise Training and Kinesiology Taping in Women With Breast Cancer-Related Lymphedema","Effects of Core-Focused Exercise Training and Kinesiology Taping Combined With Complex Decongestive Physiotherapy on Posture, Pain, Function, and Quality of Life in Women With Breast Cancer-Related Lymphedema","Inclusion Criteria:\n\n* Age between 40 and 65 years\n* Diagnosis of stage 1-2 lymphedema according to the International Society of Lymphology classification system\n* History of radical surgery due to primary breast cancer, with at least 6 months elapsed since surgery\n* Completion of cancer treatments such as chemotherapy and \u002F or radiotherapy\n* Presence of pain with a score of ≥3 on the Numeric Rating Scale (NRS) in at least one of the lumbar, thoracic, or cervical regions\n* No cooperation problems in completing the study questionnaires\n\nExclusion Criteria:\n\n* Body mass index (BMI) \\>30 kg\u002Fm²\n* Presence of active infection\n* Presence of active malignancy or metastasis\n* Presence of neurological disease\n* History of bilateral breast cancer\n* Presence of extremity deformity, scoliosis, cauda equina syndrome, or history of whiplash injury\n* Presence of motor or sensory neurological deficits (to be clinically assessed by manual muscle testing and superficial sensory examination)\n* History of spinal surgery\n* Presence of any spinal pathology",{"count":130,"type":21},[54],"The aim of the present study is to investigate the effects of trunk- focused exercise training and kinesiology taping, in addition to standard lymphedema treatment (complex decongestive therapy-CDT) on posture, pain, functionality and quality of life in women with breast cancer related lymphedema. This study is designed as a randomized placebo-controlled trial.\n\nLymphedema negatively affects the musculoskeletal system, leading to shoulder girdle muscle imbalances, cervical and thoracolumbar pain, scapular dysfunction and spinal postural alterations. Although CDT is considered the gold standard for edema management, its effects have primarily been evaluated in terms of edema reduction and symptom control, and there is limited evidence regarding its impact on posture, musculoskeletal symptoms, and quality of life, as well as the potential effects of prolonged compression bandaging applied during the intensive phase on these systems.\n\nTrunk-focused exercise training is expected to improve spinal stability, mobility and postural control, while kinesiology taping may help alleviate musculoskeletal symptoms by providing proprioceptive input and mechanical support. By combining these interventions, this study aims to provide a comprehensive rehabilitation approach targeting both physical and functional impairments. If additional improvements in posture, pain, function, and quality of life are observed compared to a control group receiving CDT combined with lower extremity exercise and placebo taping, these findings will support the added value of a multimodal rehabilitation approach beyond standard care.\n\nThe findings of this randomized placebo-controlled trial are expected to contribute to the literature by providing evidence for a comprehensive and holistic treatment approach in breast cancer-related lymphedema and to support the integration of trunk-focused exercise training and kinesiology taping into routine clinical practice. To the best of our knowledge, there is currently no randomized placebo-controlled study investigating the effects of trunk-focused exercise training and kinesiology taping in addition to CDT on posture, pain, functionality, and quality of life.",[550],"Breast Cancer Related Lymphedema","2026-06-23",{"date":383,"type":34},{"date":554,"type":21},"2026-08-15",{"date":556,"type":21},"2027-08-15",{"name":40,"class":41},{"id":559,"slug":560,"hasResults":12,"nctId":561,"briefTitle":562,"officialTitle":563,"acronym":564,"eligibilityCriteria":565,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":566,"enrollmentInfo":567,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":569,"conditions":570,"keywords":572,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":551,"lastUpdatePostDateStruct":576,"startDateStruct":577,"completionDateStruct":578,"leadSponsor":580,"locationsCount":222},"100644710","validation-of-the-turkish-brief-inventory-of-treatment-expectations-in-chronic-pain-100644710","NCT07673874","Validation of the Turkish Brief Inventory of Treatment Expectations in Chronic Pain","Turkish Cross-Cultural Adaptation, Validity, and Reliability of the \"Brief Inventory of Treatment Expectations in Chronic Pain\" (BITEC) Scale","BITEC-TR","Inclusion Criteria:\n\n* Aged 18-70 years\n* Having chronic pain for at least 3 months according to the International Association for the Study of Pain (IASP) criteria\n* Diagnosed with any chronic pain condition (e.g., fibromyalgia, nociceptive pain, neuropathic pain, etc.)\n* Being literate\n* Currently receiving any medical treatment\n\nExclusion Criteria:\n\n* Presence of cancer-related pain\n* Diagnosis of acute pain\n* Being unable to fill out the questionnaire due to a diagnosed cognitive impairment or psychiatric illness\n* Presence of visual or motor disabilities that prevent completing the questionnaire","70 Years",{"count":568,"type":21},250,"The purpose of this study is to conduct the Turkish cross-cultural adaptation, validity, and reliability study of the \"Brief Inventory of Treatment Expectations in Chronic Pain\" (BITEC) scale. Chronic pain is a complex, multidimensional experience that affects a significant portion of the adult population. Treatment expectations play a critical role in predicting clinical outcomes and directly influencing placebo\u002Fnocebo responses. While several tools exist to evaluate expectations, there is a lack of a concise, clinician-friendly, and Item Response Theory (IRT)-based instrument adapted for Turkish chronic pain populations. The BITEC is a 9-item scale that evaluates biological, psychological, and social\u002Finteractional expectation domains.\n\nThis methodological and cross-sectional study will be conducted with adult patients diagnosed with chronic pain for at least three months at Bingöl State Hospital. The study will be carried out in four consecutive stages: cross-cultural adaptation (forward and backward translation), comprehensibility pre-testing (with 30-40 volunteers), main data collection (with at least 200 participants), and statistical analyses. Data will be collected through printed forms and an online survey platform (Kobotoolbox), involving no clinical interventions. Participants will complete a sociodemographic information form, the Turkish version of the BITEC (BITEC-TR), the Treatment Expectations in Chronic Pain Scale (TEC-TR), the Pain Catastrophizing Scale (PCS), the Numerical Pain Rating Scale (NPRS), and the Hospital Anxiety and Depression Scale (HADS). Additionally, a subgroup of approximately 60 participants will recomplete the BITEC-TR 7-10 days after the initial session to evaluate test-retest reliability. Psychometric evaluation will include construct validity through exploratory and confirmatory factor analyses, and internal consistency and stability measurements.",[571],"Chronic Pain",[573,574,260,575],"treatment expectation","validation study","Cross-Cultural Adaptation",{"date":383,"type":34},{"date":36,"type":21},{"date":579,"type":21},"2027-08-31",{"name":40,"class":41},{"id":582,"slug":583,"hasResults":12,"nctId":584,"briefTitle":585,"officialTitle":586,"acronym":4,"eligibilityCriteria":587,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":588,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":590,"conditions":591,"keywords":592,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":551,"lastUpdatePostDateStruct":594,"startDateStruct":595,"completionDateStruct":596,"leadSponsor":598,"locationsCount":222},"100644649","turkish-adaptation-of-the-pain-and-smoking-inventory-100644649","NCT07673926","Turkish Adaptation of the Pain and Smoking Inventory","Turkish Cultural Adaptation and Psychometric Properties of the Pain and Smoking Inventory in Individuals With Chronic Pain","Inclusion Criteria:\n\n* Aged 18 years and older.\n* Having a diagnosis of chronic pain that has persisted for at least 3 months.\n* Smoking at least 5 cigarettes per day (within the last 30 days).\n* Being able to read and write in Turkish.\n* Volunteering to participate in the study and signing the written informed consent form.\n\nExclusion Criteria:\n\n* Having a diagnosis of active psychosis or severe depression.\n* Having a diagnosis of cognitive impairment or intellectual disability.\n* Having severe alcohol dependence or substance use disorder.\n* Having reading and writing difficulties to a degree that prevents completing the questionnaire independently.\n* Being in the pregnancy or breastfeeding period.\n* Using nicotine replacement therapy or smoking cessation medication within the last 1 month.",{"count":589,"type":21},200,"The purpose of this study is to perform the Turkish cross-cultural adaptation of the Pain and Smoking Inventory (PSI) and to comprehensively evaluate its reliability, validity, and psychometric properties among daily cigarette smokers with chronic pain.",[571],[260,593,575],"smoking",{"date":383,"type":34},{"date":36,"type":21},{"date":597,"type":21},"2027-06-30",{"name":40,"class":41},{"id":600,"slug":601,"hasResults":12,"nctId":602,"briefTitle":603,"officialTitle":604,"acronym":4,"eligibilityCriteria":605,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":606,"targetDuration":4,"studyType":52,"phases":608,"briefSummary":609,"conditions":610,"keywords":611,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":616,"lastUpdatePostDateStruct":617,"startDateStruct":618,"completionDateStruct":620,"leadSponsor":622,"locationsCount":69},"100643893","motivational-interviewing-in-thoracic-outlet-syndrome-100643893","NCT07668206","Motivational Interviewing in Thoracic Outlet Syndrome","The Effect of Motivational Interviewing on Thoracic Outlet Syndrome Symptoms in Patients With Thoracic Outlet Syndrome","Inclusion Criteria:\n\n* Diagnosis of thoracic outlet syndrome\n* Age between 18 and 65 years\n* Pain duration of more than 6 months\n* No surgical intervention in the last 6 months\n\nExclusion Criteria:\n\n* Accompanying pathologies (cervical disc problems, fibromyalgia, rotator cuff problems, diabetes, neoplastic processes)\n* Unwillingness to provide informed consent",{"count":607,"type":21},70,[54],"The goal of this clinical trial is to learn if motivational interviewing (MI) works to improve symptoms in people with thoracic outlet syndrome (TOS). TOS is a condition that causes long-term pain, numbness, and weakness in the arm and shoulder area. The main questions it aims to answer are:\n\n* Does MI lower pain and improve arm function in people with TOS?\n* Does psychological resilience predict treatment outcomes in people with TOS? Researchers will compare participants who receive MI sessions plus a home exercise program to those who receive a home exercise program alone. Participants will be randomly assigned to one of the two groups.\n\nParticipants will:\n\n* Follow a home exercise program for 6 weeks\n* Some participants will also attend up to 4 motivational interviewing sessions\n* Complete questionnaires about pain, function, sleep, anxiety, and depression at the start and end of the 6-week program",[106],[612,571,613,614,615,106],"Motivational Interviewing","Home Exercise Program","Psychological Resilience","Central Sensitization","2026-06-19",{"date":144,"type":34},{"date":619,"type":21},"2026-06",{"date":621,"type":21},"2027-10",{"name":40,"class":41},{"id":624,"slug":625,"hasResults":12,"nctId":626,"briefTitle":627,"officialTitle":628,"acronym":4,"eligibilityCriteria":629,"healthyVolunteers":12,"sex":17,"minAge":630,"maxAge":631,"enrollmentInfo":632,"targetDuration":4,"studyType":52,"phases":633,"briefSummary":634,"conditions":635,"keywords":637,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":642,"lastUpdatePostDateStruct":643,"startDateStruct":644,"completionDateStruct":646,"leadSponsor":648,"locationsCount":69},"100644232","effects-of-foot-core-exercises-in-patients-with-total-hip-arthroplasty-100644232","NCT07665801","Effects of Foot Core Exercises in Patients With Total Hip Arthroplasty","Investigation of the Effects of Foot Core Exercises on Lower Extremity Muscle Strength, Functional Parameters, and Morphological and Viscoelastic Properties of Foot and Ankle Periarticular Structures in Patients With Total Hip Arthroplasty","Inclusion Criteria:\n\n* Being between 50 and 80 years old,\n* Having at least 2 months elapsed since total hip arthroplasty surgery,\n* Being willing to participate in the study,\n* Being literate.\n\nExclusion Criteria:\n\n* Having undergone revision total hip arthroplasty surgery,\n* Having a cognitive level below 21 on the MoCA scale, or having any neurological or rheumatological disease,\n* Inability to ambulate,\n* Having any history of lower extremity trauma or other surgical procedures,\n* Having toe-related pathologies that may affect pressure distribution and the course of exercise, such as hallux valgus or Morton's neuroma.","50 Years","80 Years",{"count":314,"type":21},[54],"The goal of this clinical trial is to investigate the effects of foot core exercises on lower extremity muscle strength, viscoelastic properties, functional parameters, foot and ankle posture, balance, and the morphological characteristics of periarticular structures of the foot and ankle in individuals with total hip arthroplasty. The main questions it aims to answer are:\n\n* Does foot core exercises affect morphological characteristics of the periarticular structures surrounding the foot and ankle?\n* Does foot core exercises affect viscoelastic properties of the periarticular structures surrounding the foot and ankle?\n* Does foot core exercises affect lower extremity muscle strength?\n* Does foot core exercises affect lower extremity functional parameters and balance in individuals with total hip arthroplasty?\n\nThe researchers will compare the group performing foot core exercises with the group performing routine hip exercises that do not include foot core exercises.\n\nParticipitants will:\n\n* Participants will receive an exercise log after a specialist physiotherapist demonstrates the exercises in practice at the third postoperative mounth.\n* Visit the clinic every two months from postoperative mounth 3 to month 7 for routine follow-ups and progression of exercises.\n* Except for the control sessions held every two mounths, patients will be followed up through weekly phone calls.\n* Participants will complete an exercise diary indicating that they performed the exercises prescribed for each week, and they will bring their diaries with them to the follow-up sessions.",[636],"Total Hip Arthroplasty (THA)",[638,639,640,641],"foot core exercises","ultrasound imaging","ultrasonography","Postoperative exercises","2026-06-17",{"date":190,"type":34},{"date":645,"type":34},"2026-03-23",{"date":647,"type":21},"2027-05-31",{"name":40,"class":41},""]