[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Harran University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":451},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,16,0,[8,49,82,104,130,162,183,214,235,264,293,320,350,381,405,431],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100652381","reducing-endocrine-disrupting-chemical-exposure-in-reproductive-age-women-a-pender-model-based-rct-100652381",false,"NCT07773233","Reducing Endocrine-Disrupting Chemical Exposure in Reproductive-Age Women: A Pender Model-Based RCT","Effectiveness of a Pender's Health Promotion Model-Based Behavioral Change Intervention to Reduce Exposure to Endocrine-Disrupting Chemicals in Women of Reproductive Age: A Biomarker-Supported Randomized Controlled Trial","Inclusion Criteria:\n\n* A total of 108 women aged 18-49 years will be randomly allocated in a 1:1 ratio to an intervention or control group. The intervention group will participate in a 12-week structured behavioral change program based on Pender's Health Promotion Model. The program will include education, goal setting, action planning, self-monitoring, problem solving, social support, behavioral rehearsal, environmental restructuring, and digital reinforcement messages delivered via WhatsApp\n\nExclusion Criteria:\n\n* At the beginning of the study, women who are pregnant or breastfeeding, menopausal, have cognitive or psychiatric disorders severe enough to interfere with active participation in the study or independent completion of the data collection instruments, have a diagnosed serious endocrine disorder that could significantly affect the endocrine system (e.g., pituitary disorders or Cushing's syndrome), or have participated in a structured educational program on endocrine-disrupting chemicals within the previous six months will be excluded from the study",true,"FEMALE","18 Years","49 Years",{"count":21,"type":22},108,"ESTIMATED","INTERVENTIONAL",[25],"NA","Abstract\n\nBackground: Endocrine-disrupting chemicals (EDCs) are widely encountered in daily life and may adversely affect reproductive health. Although awareness of EDC-related risks is increasing, interventions targeting modifiable exposure-related behaviors remain limited. Theory-based behavioral interventions that address self-efficacy, perceived barriers, action planning, and maintenance of health-promoting behaviors may provide an effective approach to reducing EDC exposure.\n\nObjective: This study aims to evaluate the effectiveness of a behavioral change intervention based on Pender's Health Promotion Model in reducing EDC exposure among women of reproductive age using both behavioral outcomes and urinary biomarkers.\n\nMethods: This study is designed as a biomarker-supported, two-arm, parallel-group, open-label randomized controlled trial. A total of 108 women aged 18-49 years will be randomly allocated in a 1:1 ratio to an intervention or control group. The intervention group will participate in a 12-week structured behavioral change program based on Pender's Health Promotion Model. The program will include education, goal setting, action planning, self-monitoring, problem solving, social support, behavioral rehearsal, environmental restructuring, and digital reinforcement messages delivered via WhatsApp. EDC-related exposure behaviors, exposure perception, and attitudes will be assessed using structured measurement tools. Urinary bisphenol A (BPA) and selected phthalate metabolites will be measured before and after the intervention using liquid chromatography-tandem mass spectrometry. The primary outcome will be the between-group difference in post-intervention urinary BPA levels adjusted for baseline BPA. Secondary outcomes will include urinary phthalate metabolites, exposure-related behaviors, exposure perception, and attitudes toward EDCs.\n\nConclusion: This study will provide evidence on whether a theory-based behavioral change intervention can reduce EDC exposure at both behavioral and biological levels. Integrating Pender's Health Promotion Model with objective biomarker assessment may contribute to the development of feasible and evidence-based strategies for reducing EDC exposure among women of reproductive age.",[28,29,30],"Women Who Are Aged 18-49 Years","Able to Read, Write","Voluntarily Agree to Participate in the Study",[32,33,34,35,36],"endocrine-disrupting chemicals","bisphenol A","Pender's Health Promotion Model","behavioral change","phthalates","NOT_YET_RECRUITING","2026-08-14",{"date":40,"type":41},"2026-08-19","ACTUAL",{"date":43,"type":22},"2026-12-01",{"date":45,"type":22},"2027-12-30",{"name":47,"class":48},"Harran University","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":18,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100634903","comparison-of-5-vs-8-cmho-peep-on-respiratory-mechanics-in-prone-lumbar-surgery-100634903","NCT07545733","Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery","The Effect of Different PEEP Levels Accompanied by PCV-VG Mode on Respiratory Mechanics and Gas Exchange in Lumbar Surgeries Performed in the Prone Position Under TIVA","PROPEEP","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled for elective lumbar spine surgery in the prone position\n* Planned general anesthesia with total intravenous anesthesia (TIVA)\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Body mass index (BMI) ≥ 30 kg\u002Fm²\n* History of significant pulmonary disease (e.g., COPD, asthma)\n* Severe cardiovascular disease\n* Pregnancy\n* Known difficult airway\n* Requirement for intraoperative vasopressor infusion due to hemodynamic instability\n* Conversion to different surgical position or change in surgical plan\n* Incomplete data or protocol deviation","ALL","65 Years",{"count":60,"type":22},60,[25],"This randomized controlled clinical trial aims to compare the effects of two different positive end-expiratory pressure (PEEP) levels (5 cmH₂O and 8 cmH₂O) on respiratory mechanics in patients undergoing lumbar spine surgery in the prone position under total intravenous anesthesia (TIVA). Prone positioning may adversely affect lung compliance and gas exchange, making optimal ventilatory strategies essential. Driving pressure and mechanical power are considered key determinants of ventilator-induced lung stress. This study will evaluate the impact of different PEEP levels on respiratory parameters and intraoperative physiological changes.",[64,65,66,67],"Lumbar Disc Herniation","Spinal Surgery","Prone Position","General Anesthesia",[69,70,71,72,66,73],"PEEP","Driving Pressure","Mechanical Power","PCV-VG Ventilation","Lung Protective Ventilation","2026-08-10",{"date":76,"type":41},"2026-08-11",{"date":78,"type":22},"2026-08-15",{"date":80,"type":22},"2026-10-03",{"name":47,"class":48},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":57,"minAge":18,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100638700","effects-of-two-anesthesa-technques-on-inflammatory-response-and-amno-acd-metabolsm-n-thyrod-surgery-100638700","NCT07592832","EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY","THE EFFECT OF TWO DİFFERENT ANESTHESİA APPROACHES ON PERİOPERATİVE INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY","Inclusion Criteria:\n\n* This includes patients aged 18-70 years\n* classified as ASA I-III\n* who have undergone elective thyroidectomy.\n\nExclusion Criteria:\n\n* Patients who did not wish to participate in the study voluntarily\n* patients for whom superficial cervical block was contraindicated\n* pregnant and breastfeeding women\n* patients in ASA IV-V groups were excluded from the study.","70 Years",{"count":60,"type":22},[25],"The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.",[67,94,95],"Cervical Plexus Block","Thyroid Surgery","2026-05-15",{"date":98,"type":41},"2026-05-18",{"date":100,"type":22},"2026-07-30",{"date":102,"type":22},"2027-02-20",{"name":47,"class":48},{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":16,"sex":57,"minAge":18,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":23,"phases":113,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":127,"leadSponsor":129,"locationsCount":4},"100639706","positive-psychology-based-psychoeducation-for-psychological-flexibility-and-perceived-stress-in-university-students-100639706","NCT07579767","Positive Psychology Based Psychoeducation for Psychological Flexibility and Perceived Stress in University Students","The Effect of a Multi-Component Positive Psychology-Based Psychoeducation Program on Psychological Flexibility and Perceived Stress in University Students: A Controlled Pretest-Posttest Study","Inclusion Criteria:\n\n1. Being a first-year undergraduate student in the Department of Nursing at Harran University.\n2. Volunteering to participate in the study and providing informed consent.\n3. Having no reading, comprehension, or communication difficulty that would prevent completion of the data collection tools.\n4. Being 18 years of age or older.\n\nExclusion Criteria:\n\n1. Receiving regular psychotherapy or psychoeducation during the same academic period.\n2. Having participated in a structured positive psychology-based psychoeducation or intervention program within the last 6 months.\n3. Having a history of psychiatric hospitalization within the last 3 months or having an acute psychiatric crisis or instability that would make participation in the sessions inappropriate.",{"count":112,"type":22},66,[25],"This study will test whether an 8-week multi-component positive psychology-based psychoeducation program can reduce perceived stress and improve psychological flexibility among first-year undergraduate nursing students. Eligible students who provide informed consent will be randomly assigned to either an intervention group or a waitlist control group. The intervention group will attend weekly 60-75 minute psychoeducation sessions including brief psychoeducation, experiential exercises, shared reflection, and home practice assignments. The waitlist control group will continue their usual routine during the study period and will not receive any intervention before post-test assessment. Outcomes will be assessed at baseline and immediately after the 8-week program using the Perceived Stress Scale-14 and the Acceptance and Action Questionnaire-II.",[116,117],"Stress, Psychological","Psychological Flexibility",[119,120,121,117,122],"Positive Psychology","Psychoeducation","Perceived Stress","University Students","2026-05-05",{"date":125,"type":41},"2026-05-12",{"date":96,"type":22},{"date":128,"type":22},"2026-07-31",{"name":47,"class":48},{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":23,"phases":141,"briefSummary":142,"conditions":143,"keywords":145,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":161},"100640549","impact-of-post-cesarean-abdomino-pelvic-training-on-diastasis-recti-and-sexual-function-100640549","NCT07575490","Impact of Post-Cesarean Abdomino-Pelvic Training on Diastasis Recti and Sexual Function","The Impact of Structured Postoperative Abdomino-Pelvic Power-Training on Diastasis Recti Abdominis, Pelvic Hemodynamics, and Sexual Function Following Cesarean Section: A Prospective, Randomized Controlled, Doppler Morphometric Analysis Study","APPT-S","Inclusion Criteria:Primiparous women (first-time mothers).\n\nWomen who have undergone an elective cesarean section.\n\nParticipants who are at their 6th week postpartum at the start of the study.\n\nAged between 18 and 45 years.\n\nVolunteering to participate and capable of signing the informed consent form.\n\n\\-\n\nExclusion Criteria:\n\n* Multiparous women (those with more than one delivery).\n\nWomen with a history of previous abdominal or pelvic surgery (other than the current C-section).\n\nPresence of chronic diseases (e.g., uncontrolled diabetes, hypertension, or connective tissue disorders).\n\nAny musculoskeletal or neurological condition that prevents participation in an exercise program.\n\nHistory of pelvic organ prolapse or severe urinary incontinence prior to pregnancy.\n\nActive pelvic or abdominal infection.\n\nParticipants who have already started a structured postpartum exercise program elsewhere.","45 Years",{"count":140,"type":22},120,[25],"This study aims to investigate the effects of a specific exercise program on physical recovery and sexual health in women who have had a cesarean section. Pregnancy and abdominal surgery can lead to a separation of the abdominal muscles, known as Diastasis Recti Abdominis (DRA), and may affect pelvic health and sexual function. Participants will be randomly assigned to either an intervention group or a control group. The intervention group will participate in a 6-week \"Structured Abdomino-Pelvic Power-Training\" program starting at the 6th week after surgery. This program includes specific exercises to strengthen the core and pelvic floor muscles. The control group will follow the standard routine postpartum care. The researchers will use ultrasound and Doppler imaging to measure the distance between the abdominal muscles and the blood flow in the pelvic area at the beginning of the study and after 6 weeks of training. Participants will also complete a validated questionnaire (FSFI) to evaluate their sexual function. The goal of the research is to determine if this structured exercise program helps close the abdominal gap more effectively and improves pelvic blood flow and sexual well-being compared to standard care.",[144],"Diastasis Recti Abdominis Postpartum Period Cesarean Section Sexual Dysfunction, Physiological Pelvic Floor Muscle Training",[146,147,148,149,150,151,152],"Vaginal Doppler","Pelvic Hemodynamics","Abdomino-pelvic Training","FSFI (Female Sexual Function Index)","Post-cesarean Recovery","Core Stabilization","Uterine Artery Doppler","2026-05-02",{"date":155,"type":41},"2026-05-08",{"date":157,"type":22},"2026-05",{"date":159,"type":22},"2026-12",{"name":47,"class":48},2,{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":11,"sex":57,"minAge":18,"maxAge":58,"enrollmentInfo":169,"targetDuration":4,"studyType":23,"phases":170,"briefSummary":171,"conditions":172,"keywords":4,"overallStatus":174,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":179,"leadSponsor":181,"locationsCount":182},"100615305","comparing-the-postoperative-analgesic-efficacy-of-anterior-iliac-block-and-ilioinguinal-iliohypogastric-block-in-inguinal-hernia-surgery-100615305","NCT07290881","Comparing the Postoperative Analgesic Efficacy of Anterior Iliac Block and Ilioinguinal-iliohypogastric Block in Inguinal Hernia Surgery","A Prospective Randomized Study Comparing the Postoperative Analgesic Efficacy of Anterior Iliac Block and Ilioinguinal-iliohypogastric Block in Inguinal Hernia Surgery","Inclusion Criteria:\n\n* It includes patients aged 18-65 years\n* Classified as ASA I-II\n* Who are undergoing elective inguinal hernia surgery\n\nExclusion Criteria:\n\n* Patients who did not wish to participate voluntarily\n* Those with contraindications to the anterior iliac block or the Ilioinguinal\u002FIliohypogastric block,\n* Pregnant or breastfeeding women\n* Patients classified as ASA III-IV-V",{"count":60,"type":22},[25],"The primary aim of this study is to compare two postoperative analgesia techniques used in patients undergoing inguinal hernia surgery-(1) the anterior iliac block and (2) the ilioinguinal\u002Filiohypogastric block-in terms of postoperative analgesia duration and patient satisfaction.\n\nEffective postoperative analgesia in inguinal hernia surgery is crucial for improving patient comfort and reducing opioid consumption. Although ilioinguinal and iliohypogastric nerve blocks are commonly used for this purpose, their relatively limited dermatomal coverage may result in inadequate analgesia in some cases. The recently described Anterior Iliac Block has been proposed as an alternative to conventional techniques, offering potentially wider neural spread and more effective postoperative pain control. However, the efficacy and safety of this novel block have not yet been sufficiently evaluated in the literature.",[173],"Acute Pain","RECRUITING","2026-04-20",{"date":177,"type":41},"2026-04-21",{"date":175,"type":41},{"date":180,"type":22},"2026-09-01",{"name":47,"class":48},1,{"id":184,"slug":185,"hasResults":11,"nctId":186,"briefTitle":187,"officialTitle":188,"acronym":4,"eligibilityCriteria":189,"healthyVolunteers":16,"sex":57,"minAge":190,"maxAge":4,"enrollmentInfo":191,"targetDuration":4,"studyType":23,"phases":193,"briefSummary":194,"conditions":195,"keywords":199,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":4},"100632438","the-effect-of-digital-literacy-education-based-on-social-learning-theory-on-digital-addiction-and-social-comparison-in-fourth-grade-students-100632438","NCT07513688","The Effect of Digital Literacy Education Based on Social Learning Theory on Digital Addiction and Social Comparison in Fourth-Grade Students","The Effect of Digital Literacy Education Based on Social Learning Theory on Digital Addiction and Social Comparison in Fourth-Grade Students: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Being a 4th-grade student at a public elementary school in the city center of Şanlıurfa\n* The student and their parent or guardian must complete a written informed consent form to participate in the study\n* The student must not have any mental or physical conditions that would prevent communication\n\nExclusion Criteria:\n\n* Refusal to complete a written informed consent form for the student and parent's participation in the study\n* Presence of a mental or physical illness that impairs communication\n* Withdrawal from school during the study period due to reasons such as absenteeism\n* Withdrawal of parental consent by the parents themselves during the study period\n* Failure to participate in at least one of the pre-test or post-test measurements\n* Currently receiving counseling for digital addiction or another psychological disorder 9","9 Years",{"count":192,"type":22},200,[25],"Introduction and Aims:\n\nDigital technologies have significantly transformed children's learning levels, communication skills, and socialization patterns. However, the early and uncontrolled use of digital tools can lead to an increase in digital addiction tendencies among children and intensify social comparisons with peers. Elementary school-aged children, in particular, are in a sensitive period of growth and development when their behavioral patterns and self-perceptions are being shaped. Therefore, there is a need for school-based, nurse-led, theory-based educational programs that support children in developing healthy and conscious behaviors on digital platforms. Social Learning Theory provides a strong framework for such interventions by explaining that children's digital behaviors are shaped through observation, modeling, self-regulation, and self-evaluation processes. The aim of this study is to examine the effect of the Digital Literacy Education Program, developed based on Social Learning Theory, on digital addiction and social comparison among fourth-grade elementary school students.\n\nMethod:\n\nThis study will be conducted as a two-phase, prospective, single-center, two-group (1:1) parallel design, pre-test-post-test randomized controlled trial. Social Learning Theory is a theoretical framework consisting of six components to understand and support behavioral change. In the first phase, Digital Literacy Education based on Social Learning Theory will be developed, and in the second phase, its effectiveness will be evaluated with 200 students. The sample will consist of 200 fourth-grade students studying in central Şanlıurfa, who will be divided into intervention and control groups at a 1:1 ratio. Participants in the intervention group will receive a three-week, multi-component training program based on Social Learning Theory, while participants in the control group will receive routine general advice. Assessments will be conducted at the beginning, after the training, and at 6 months. Research data will be collected using a Personal Information Form, the Digital Addiction Scale for Children, the Digital Literacy Scale for Elementary School Students, and the Social Comparison Scale. The data will be evaluated using descriptive statistical analyses and relevant tests",[196,197,198],"Digital Literacy","Digital Addiction","Social Comparison",[200,201,202,203,204,205],"digital addiction","social comparison","fourth-grade student","digital literacy education","social learning theory","randomized controlled trial","2026-03-30",{"date":208,"type":41},"2026-04-07",{"date":210,"type":22},"2026-04",{"date":212,"type":22},"2027-04-29",{"name":47,"class":48},{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":218,"acronym":4,"eligibilityCriteria":219,"healthyVolunteers":11,"sex":57,"minAge":18,"maxAge":58,"enrollmentInfo":220,"targetDuration":4,"studyType":23,"phases":222,"briefSummary":223,"conditions":224,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":4},"100623637","comparison-of-the-metabolomic-effects-of-sevoflurane-and-desflurane-anesthesia-in-laparoscopic-cholecystectomy-100623637","NCT07399223","Comparison of the Metabolomic Effects of Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* Patients undergoing laparoscopic cholecystectomy surgery who have no active infection, Body mass index (BMI)\\\u003C35, Aged 18-65, ASA I-II, and who agree to participate in the study\n\nExclusion Criteria:\n\n* Individuals over 65 years of age ASA 3-4 patients Individuals with a body mass index (BMI) \\>35 Smokers",{"count":221,"type":22},80,[25],"Analytical techniques used in metabolomic studies include nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). The study will involve comparing the metabolomic profiles of patients receiving sevoflurane and desflurane during surgery to identify any differences in metabolic pathways affected by the two anaesthetic techniques. Metabolomic profiles are generated using spectroscopic and spectrometric techniques such as high-field NMR and MS, as well as separation techniques.",[225,226],"Sevoflurane Desflurane","Metabolomic Effect","2026-02-20",{"date":229,"type":41},"2026-02-23",{"date":231,"type":22},"2026-02",{"date":233,"type":22},"2026-05-30",{"name":47,"class":48},{"id":236,"slug":237,"hasResults":11,"nctId":238,"briefTitle":239,"officialTitle":240,"acronym":241,"eligibilityCriteria":242,"healthyVolunteers":11,"sex":57,"minAge":18,"maxAge":4,"enrollmentInfo":243,"targetDuration":4,"studyType":23,"phases":245,"briefSummary":246,"conditions":247,"keywords":251,"overallStatus":174,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":182},"100612574","effect-of-kinesio-taping-applied-to-the-suprahyoid-muscles-on-swallowing-safety-in-patients-with-post-stroke-dysphagia-100612574","NCT07255352","Effect of Kinesio Taping Applied to the Suprahyoid Muscles on Swallowing Safety in Patients With Post-Stroke Dysphagia","Investigation of the Effects of Suprahyoid Kinesio Taping on Swallowing Safety and Hyolaryngeal Elevation in Patients With Post-Stroke Dysphagia","Post-Stroke KT","Inclusion Criteria:\n\n* Diagnosis of stroke\n* Age over 18 years\n* Presence of swallowing disorder symptoms\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Presence of neurological diseases other than stroke\n* Presence of tracheostomy\n* Open wounds on the skin in the submental region",{"count":244,"type":22},25,[25],"Dysphagia is defined as a disorder that occurs during the process of food transfer, beginning with oral intake and continuing until it reaches the stomach. The incidence of post-stroke dysphagia has been reported to range between 42% and 75%. Dysphagia can lead to aspiration pneumonia due to food entering the lungs, as well as malnutrition, dehydration, and even death. In patients with inadequate swallowing safety and efficiency, compensatory maneuvers such as chin tuck, head flexion, supraglottic swallowing, and the Mendelsohn maneuver are commonly used. These maneuvers aim to maintain oral intake by narrowing the laryngeal vestibule or increasing hyolaryngeal elevation. They are evaluated during videofluoroscopic swallowing studies and recommended to patients if they are found to prevent aspiration or penetration.\n\nKinesio taping (KT) has been reported to stimulate cutaneous receptors, increase sensory input, and facilitate neural reflexes, thereby promoting the activation of a greater number of motor units during maximal muscle contraction. In recent years, it has also begun to be used in the field of dysphagia rehabilitation. Studies conducted in stroke patients have shown that KT applied to the infrahyoid muscles provides resistance to the suprahyoid muscles and enhances their strength. A kinematic analysis study in stroke patients reported that KT applied to include the suprahyoid muscles increased vertical hyoid movement, although it did not result in a significant improvement in swallowing safety. The study, however, did not specify the detailed taping method used. Since the suprahyoid muscles are primarily responsible for hyolaryngeal elevation, KT focusing on this region has the potential to serve as a compensatory maneuver in dysphagia management.",[248,249,250],"Stroke","Dysphagia","Swallowing Disorder",[252,253,254,255],"Kinesio Taping","Suprahyoid Muscles","Hyolaryngeal Elevation","Videofluoroscopic Swallowing Study","2025-11-20",{"date":258,"type":41},"2025-12-01",{"date":260,"type":41},"2025-04-01",{"date":262,"type":22},"2026-10-01",{"name":47,"class":48},{"id":265,"slug":266,"hasResults":11,"nctId":267,"briefTitle":268,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":16,"sex":57,"minAge":18,"maxAge":58,"enrollmentInfo":271,"targetDuration":4,"studyType":23,"phases":273,"briefSummary":274,"conditions":275,"keywords":280,"overallStatus":174,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":182},"100606818","evaluation-of-the-effect-of-tea-tree-and-chlorhexidine-mouthwashes-on-healing-after-third-molar-extraction-100606818","NCT07180498","Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction","The Evaluation of the Effects of Chlorhexidine and Tea Tree Oil Mouthwash on Postoperative Complications and Periodontal Healing After the Extraction of Impacted Third Molars","Inclusion Criteria:\n\n* Individuals undergoing extraction of Class 2, Class B mandibular third molars impacted in the lower jaw (Pell \\& Gregory).\n* Individuals aged 18-65.\n* Individuals must be in stable general health (e.g., free of serious cardiovascular or kidney disease).\n* Individuals willing to use tea tree extract or other treatments.\n\nExclusion Criteria:\n\n* Individuals with a known allergy or hypersensitivity to tea tree extract.\n* Individuals with serious illnesses such as heart failure or kidney disease. Patients with bleeding disorders.\n* Individuals during pregnancy and breastfeeding.\n* Individuals taking medications that may interact with tea tree extract (e.g., blood thinners or antihypertensives)\n* Individuals previously treated for edema.\n* Individuals with chronic edema.",{"count":272,"type":22},54,[25],"The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars. Additionally, the effects on periodontal health will be examined by comparing the gum healing processes of patients using both mouthwashes.The main questions it aims to answer are:\n\n1. Tea tree oil, said to have anti-inflammatory and antibacterial effects, could be an alternative to chlorhexidine in reducing postoperative complications after impacted tooth extraction.\n2. Does tea tree oil, which has antimicrobial effects, have as positive an impact on periodontal health as chlorhexidine?Researchers will compare tea tree oil to chlorhexidine (routinely prescribed after the extraction of an impacted wisdom tooth) to see if tea tree oil works to decrease postoperative complications.\n\nParticipants will:\n\nFor 7 days after the operation, they will gargle with chlorhexidine mouthwash or mouthwash containing tea tree oil 3 times a day. They will come to the clinic for check-ups and measurements on the 2nd and 7th days after the operation. They will record their pain levels and the number of painkillers they take daily.",[276,277,278,279],"Postoperative Pain","Postoperative Complications","Trismus","Periodontal Health",[281,282,283,284],"tea tree oil","third molar surgery","postoperative complications","chlorhexidine digluconate","2025-09-15",{"date":287,"type":41},"2025-09-18",{"date":289,"type":41},"2025-04-15",{"date":291,"type":22},"2025-12-30",{"name":47,"class":48},{"id":294,"slug":295,"hasResults":11,"nctId":296,"briefTitle":297,"officialTitle":298,"acronym":4,"eligibilityCriteria":299,"healthyVolunteers":11,"sex":57,"minAge":300,"maxAge":301,"enrollmentInfo":302,"targetDuration":303,"studyType":304,"phases":4,"briefSummary":305,"conditions":306,"keywords":308,"overallStatus":174,"whyStopped":4,"lastUpdateSubmitDate":313,"lastUpdatePostDateStruct":314,"startDateStruct":316,"completionDateStruct":318,"leadSponsor":319,"locationsCount":182},"100606100","detection-of-disease-marker-factors-in-cyst-fluid-100606100","NCT07171151","Detection of Disease Marker Factors in Cyst Fluid","Measurement of MMP-8, MMP-9, RANKL, MIP-1alpha in Biopsy Samples From Odontogenic Cyst Patients","Inclusion Criteria:\n\n1. Individuals diagnosed with cysts\n2. Individuals who are not pregnant or breastfeeding\n3. Individuals who agree to sign the informed consent form\n\nExclusion Criteria:\n\n1. Systemically ill individuals who are contraindicated for surgery.\n2. Individuals who do not wish to sign the informed consent form.\n3. Individuals who are pregnant, breastfeeding, or using oral contraceptives will be excluded.","12 Years","80 Years",{"count":244,"type":22},"2 Weeks","OBSERVATIONAL","The purpose of this observational study is to examine the cyst fluid obtained after a puncture procedure performed for cyst diagnosis in participants with cystic lesions on clinical and radiological examination.The main question it aims to answer is:\n\n\\- What is the exact mechanism of formation of odontogenic cysts?\n\nBiomarkers in the cyst fluid obtained after a puncture procedure performed as part of the diagnosis and treatment process of odontogenic cysts will be examined. The aim of this study is to gain insight into cyst pathology by examining the levels of biomarkers in odontogenic cyst fluid.",[307],"Biomarkers",[309,310,311,312],"odontogenic cysts","biomarkers","MMP-8","MIP-1alfa","2025-09-09",{"date":315,"type":41},"2025-09-12",{"date":317,"type":41},"2025-08-25",{"date":157,"type":22},{"name":47,"class":48},{"id":321,"slug":322,"hasResults":11,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":4,"eligibilityCriteria":326,"healthyVolunteers":16,"sex":57,"minAge":327,"maxAge":328,"enrollmentInfo":329,"targetDuration":4,"studyType":23,"phases":331,"briefSummary":332,"conditions":333,"keywords":336,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":342,"lastUpdatePostDateStruct":343,"startDateStruct":345,"completionDateStruct":347,"leadSponsor":349,"locationsCount":182},"100597169","investigation-of-the-effects-of-basic-body-awareness-training-on-motor-skills-n-children-at-risk-of-developmental-delay-100597169","NCT07054996","Investigation of the Effects of Basic Body Awareness Training on Motor Skills İn Children at Risk of Developmental Delay","Investigation of the Effects of Basic Body Awareness Training on Motor Skills, Play Skills, and Social Participation in Children at Risk of Developmental Delay","Inclusion Criteria:\n\n* Children aged 4 to 6 years attending preschool\n* Those who voluntarily agreed to participate in the study\n\nExclusion Criteria:\n\n* Children with neurological problems\n* Children who are uncooperative\n* Children receiving speech and language therapy","4 Years","6 Years",{"count":330,"type":22},72,[25],"The aim of this study is to investigate the effects of basic body awareness training on preschool children with developmental delays.",[334,335],"Developmental Delay","Body Perception",[337,338,339,340,341],"basic body awareness therapy","Motor development","Body perception","Mental rotation","developmental delay","2025-07-03",{"date":344,"type":41},"2025-07-08",{"date":346,"type":22},"2025-07",{"date":348,"type":22},"2025-12",{"name":47,"class":48},{"id":351,"slug":352,"hasResults":11,"nctId":353,"briefTitle":354,"officialTitle":355,"acronym":4,"eligibilityCriteria":356,"healthyVolunteers":16,"sex":57,"minAge":18,"maxAge":4,"enrollmentInfo":357,"targetDuration":4,"studyType":304,"phases":4,"briefSummary":358,"conditions":359,"keywords":367,"overallStatus":174,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":380,"locationsCount":182},"100589962","effectiveness-of-ventilation-modes-in-intensive-care-a-comparison-of-mandatory-minute-ventilation-and-synchronized-intermittant-mandatory-ventilation-using-bioelectrical-impedance-tomography-100589962","NCT06961227","Effectiveness of Ventilation Modes in Intensive Care: A Comparison of Mandatory Minute Ventilation and Synchronized Intermittant Mandatory Ventilation Using Bioelectrical Impedance Tomography","Comparative Analysis of Ventilation Distribution in Intensive Care: Mandatory Minute Ventilation Versus Synchronized Intermittent Mandatory Ventilation Using Electrical Impedance Tomography\"","Inclusion Criteria:\n\n* Age ≥ 18 years\n\nIntubated and receiving invasive mechanical ventilation\n\nHemodynamically stable (no vasopressor support)\n\nFiO₂ ≤ 60%\n\nPEEP ≤ 8 cmH₂O\n\nNot receiving neuromuscular blocking agents\n\nAble to tolerate switching between SIMV and MMV modes\n\nExclusion Criteria:\n\nPregnant or breastfeeding patients\n\nPatients with neuromuscular diseases affecting respiratory drive\n\nUnstable hemodynamics or ongoing need for vasopressors\n\nPatients requiring high PEEP (\\>8 cmH₂O)\n\nPatients with DNR (do not resuscitate) status\n\nParticipation in another interventional study\n\n\\-",{"count":244,"type":22},"Synchronized Intermittent Mandatory Ventilation (SIMV) is a commonly used ventilatory mode available in many modern ventilators, frequently applied in intensive care units for patients requiring invasive mechanical ventilation. SIMV delivers a preset tidal volume or pressure at a predetermined respiratory rate and synchronizes with the patient's spontaneous breathing efforts, thereby enhancing patient-ventilator interaction and contributing to rehabilitation.\n\nMandatory Minute Ventilation (MMV) is a hybrid mode combining features of SIMV and Pressure Support Ventilation (PSV), guaranteeing a preset minute ventilation (tidal volume × respiratory rate). It synchronizes support based on the patient's spontaneous efforts and compensates in cases of insufficient minute ventilation.\n\nElectrical Impedance Tomography (EIT) is a non-invasive, radiation-free imaging technique that enables real-time monitoring of pulmonary ventilation and perfusion by applying alternating electrical currents through surface electrodes. EIT has demonstrated strong correlation with findings from computed tomography, nitrogen washout, PET, and SPECT imaging modalities.\n\nThis study aims to evaluate the effectiveness of MMV compared to SIMV in mechanically ventilated, hemodynamically stable adult patients (\\>18 years old) in the intensive care unit. Patients must not require vasopressors, have a FiO₂ ≤ 60%, PEEP ≤ 8 cmH₂O, or receive neuromuscular blocking agents.\n\nPatients will be monitored under both SIMV and MMV modes, separated by a 12-hour interval. To minimize carry-over effects, a one-hour washout period will be implemented before data collection with EIT. Key parameters including PO₂\u002FFiO₂ ratio, PaCO₂, and EtCO₂ will be assessed. The sequence of ventilatory mode application will follow a crossover study design.",[360,361,362,363,364,365,366],"Ventilation Modes","Mechanical Ventilation","Critical Illness","Respiratory Support","Intensive Care Unit (ICU) Patients","Mechanical Ventilation Dependence","Evaluation of Mechanical Ventilation Modes (SIMV and MMV) in Adult Intensive Care Unit Patients Using Electrical Impedance Tomography",[361,368,369,370,371,372],"SIMV","MMV","Electrical Impedance Tomography","EIT","Intensive Care Unit","2025-04-29",{"date":375,"type":41},"2025-05-07",{"date":377,"type":41},"2025-03-10",{"date":379,"type":22},"2025-10-31",{"name":47,"class":48},{"id":382,"slug":383,"hasResults":11,"nctId":384,"briefTitle":385,"officialTitle":386,"acronym":4,"eligibilityCriteria":387,"healthyVolunteers":16,"sex":57,"minAge":4,"maxAge":4,"enrollmentInfo":388,"targetDuration":4,"studyType":304,"phases":4,"briefSummary":389,"conditions":390,"keywords":395,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":397,"lastUpdatePostDateStruct":398,"startDateStruct":400,"completionDateStruct":402,"leadSponsor":404,"locationsCount":182},"100585910","adaptation-of-the-intensive-care-unit-specific-pressure-injury-risk-scale-to-turkish-raps-icu-100585910","NCT06908512","Adaptation of the Intensive Care Unit-specific Pressure Injury Risk Scale to Turkish (RAPS-ICU)","Turkish Adaptation, Validity and Reliability of the Intensive Care Unit-specific Pressure Injury Risk Assessment Scale","Inclusion Criteria:\n\n* 18 years of age or older,\n* Staying in the Intensive Care Unit for at least 1 day,\n* Agreeing to participate in the study by themselves or a family member.\n* Volunteering to participate in the research\n* Full orientation and no psychiatric problems\n\nExclusion Criteria:\n\n\\- Having communication problems",{"count":60,"type":22},"The aim of this study was to evaluate the translation, cross-cultural fit, and psychometric properties of the ICU-specific pressure injury risk scale",[391,392,393,394],"Pressure Injury","Reliability and Validity","Intensive Care Units (ICUs)","Assessment Scale",[391,392,396,394],"Intensive Care Units","2025-03-26",{"date":399,"type":41},"2025-04-03",{"date":401,"type":22},"2025-03-30",{"date":403,"type":22},"2025-11-12",{"name":47,"class":48},{"id":406,"slug":407,"hasResults":11,"nctId":408,"briefTitle":409,"officialTitle":410,"acronym":4,"eligibilityCriteria":411,"healthyVolunteers":16,"sex":57,"minAge":412,"maxAge":18,"enrollmentInfo":413,"targetDuration":4,"studyType":23,"phases":415,"briefSummary":416,"conditions":417,"keywords":419,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":426,"completionDateStruct":428,"leadSponsor":430,"locationsCount":182},"100567027","ergonomics-and-first-aid-training-for-children-of-seasonal-agricultural-worker-families-100567027","NCT06662838","Ergonomics and First Aid Training for Children of Seasonal Agricultural Worker Families","Evaluation of Ergonomics Awareness and First Aid Training Activities Given to Children of Seasonal Agricultural Worker Families","Inclusion Criteria:\n\n* Children who are between the ages of 14 and 18, who have no communication problems, who volunteer to participate in the research, and whose families have worked as seasonal agricultural workers at least once in their lives will be included in the study.\n\nExclusion Criteria:\n\n* Children who do not meet the sample selection criteria, do not attend ergonomic awareness and first aid training, or drop out of training will be excluded from the study.","14 Years",{"count":414,"type":22},140,[25],"The aim of this project is to evaluate the effectiveness of ergonomic awareness and first aid training given to children of seasonal agricultural worker families.",[418],"Worker Disease, Agricultural",[420,421,422],"child","ergonomics","first aid","2024-10-26",{"date":425,"type":41},"2024-10-29",{"date":427,"type":22},"2024-11-07",{"date":429,"type":22},"2024-12-20",{"name":47,"class":48},{"id":432,"slug":433,"hasResults":11,"nctId":434,"briefTitle":435,"officialTitle":436,"acronym":4,"eligibilityCriteria":437,"healthyVolunteers":16,"sex":57,"minAge":18,"maxAge":58,"enrollmentInfo":438,"targetDuration":4,"studyType":304,"phases":4,"briefSummary":440,"conditions":441,"keywords":4,"overallStatus":174,"whyStopped":4,"lastUpdateSubmitDate":443,"lastUpdatePostDateStruct":444,"startDateStruct":446,"completionDateStruct":448,"leadSponsor":450,"locationsCount":182},"100554477","duke-activity-score-index-in-obese-individuals-100554477","NCT06499597","Duke Activity Score Index in Obese Individuals","Investigation of Psychometric Properties of Duke Activity Score Index in Obese Individuals Candidate for Bariatric Surgery","Inclusion Criteria:\n\n* Body mass index higher than 30\n* No disease that may affect functional performance\n* Able to adapt to the tests to be applied\n\nExclusion Criteria:\n\n* Recently hospitalized due to a condition that may make it difficult to perform the test\n* Inability to perform exercise tests due to neurological or musculoskeletal disorders\n* Uncontrollable medical conditions (such as lung or cardiovascular disease)\n* Dysfunction of the vestibular system or eyes",{"count":439,"type":22},40,"Today, obesity is a global health problem and can lead to serious health complications. Bariatric surgery is recognized as an effective treatment option to achieve long-term weight loss and health improvement in overweight or obese individuals. However, appropriate tools are needed to assess the physical activity levels of patients before and after bariatric surgery and to guide rehabilitation processes after surgery. The Duke Activity Index (DAI) is a scale used to assess activities of daily living and was developed at Duke University Medical Center. The DAI has been widely used to determine patients' physical functioning and monitor their activity levels in various health conditions and post-surgical recovery processes. The aim of this study was to evaluate the psychometric properties of the DAI and to examine whether it is an effective tool for determining physical activity levels in patients who are candidates for bariatric surgery.",[442],"Obesity, Morbid","2024-07-11",{"date":445,"type":41},"2024-07-12",{"date":447,"type":41},"2024-03-01",{"date":449,"type":22},"2024-08-01",{"name":47,"class":48},""]