[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Holy Family Hospital, Nazareth, Israel\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":227},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,45,69,92,120,143,170,189,208],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100652594","tens-use-for-post-cesarean-pain-management-100652594",false,"NCT07777939","TENS Use for Post-cesarean Pain Management","Continuous 24-Hour Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Management: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Women aged 18-45 years.\n* Undergoing CD under spinal anesthesia.\n* Hemodynamically stable postoperatively.\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Undergoing CD under epidural or general anesthesia.\n* Skin lesions or infection at electrode placement sites.\n* Pacemaker or implanted electrical devices.\n* Neurological disorders affecting pain perception.\n* Chronic opioid use or chronic pain disorders.\n* Allergy or other contraindication to opioids, nonsteroidal antiinflammatory drugs, or acetaminophen use.\n* Adhesive allergy.\n* Midline vertical skin incision (in the current or previous cesarean).\n* Intraoperative sterilization.\n* Cesarean hysterectomy.","FEMALE","18 Years","45 Years",{"count":20,"type":21},196,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this randomized controlled trial is to evaluate the effectiveness of continuous 24-hour Transcutaneous Electrical Nerve Stimulation (TENS) as an adjunct to standard postoperative care for pain management following cesarean delivery. Eligible women undergoing cesarean delivery under spinal anesthesia will be randomly assigned in a 1:1 ratio to either the intervention group, which will receive continuous TENS in addition to standard postoperative analgesia, or the control group, which will receive standard postoperative analgesia alone. The primary outcome is the Quality of Recovery-15 (QoR-15) score assessed 24 hours after cesarean delivery.",[27],"Post Cesarean Pain Management",[29,30,31],"Cesarean delivery","TENS","POSTPARTUM PAIN","NOT_YET_RECRUITING","2026-08-18",{"date":35,"type":36},"2026-08-20","ACTUAL",{"date":38,"type":21},"2026-08",{"date":40,"type":21},"2027-09",{"name":42,"class":43},"Holy Family Hospital, Nazareth, Israel","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":64,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},"100647195","tens-for-postpartum-uterine-pain-during-breastfeeding-100647195","NCT07703917","TENS for Postpartum Uterine Pain During Breastfeeding","Transcutaneous Electrical Nerve Stimulation for Treating Postpartum Uterine Pain During Breastfeeding in Multiparous Women: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Maternal Age above 18\n* Term delivery (37 weeks or more)\n* Vaginal delivery within the past 48 hours.\n* Multiparous women (2 or more previous births)\n* Delivery of a singleton\n* Have the well to breastfeed\n\nExclusion Criteria:\n\n* Contraindication to TENS (pacemaker, epilepsy, active infection, uncontrolled hyper \u002F hypotension.)\n* Chronic analgesia use\n* Severe complications requiring intervention (severe PPH) or intensive care\n* Skin lesions, infections, or scars at proposed electrode sites\n* Neonatal intensive care unit admission",true,{"count":54,"type":21},124,[24],"This clinical study is designed to evaluate whether Transcutaneous Electrical Nerve Stimulation (TENS) is an effective, non-drug method to relieve postpartum uterine pain during breastfeeding in multiparous women (women who have given birth multiple times). Breastfeeding in the first 48 hours after delivery often triggers strong, painful uterine contractions due to the natural release of oxytocin. While standard care typically relies on pain-relief medications, this study investigates if TENS, a safe, low-cost device that sends gentle electrical impulses through small skin patches, can significantly reduce this pain and decrease the need for systemic medications. Participants will be randomly assigned to either receive standard postpartum pain medications or use a TENS device during two consecutive breastfeeding sessions. Researchers will measure and compare the peak pain levels between both groups using a standard 0 to 10 pain scale. The aim is examining whether TENS will significantly reduce postpartum uterine pain during breastfeeding and decrease medication use compared with standard care.",[58],"Breast Feeding",[60,30,31],"BREASTFEEDING","RECRUITING","2026-08-15",{"date":33,"type":36},{"date":62,"type":36},{"date":66,"type":21},"2027-08-01",{"name":42,"class":43},2,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":44},"100333861","maternal-outcomes-following-manual-lysis-of-the-placenta-100333861","NCT03626844","Maternal Outcomes Following Manual Lysis of the Placenta.","Maternal Outcomes Following Manual Lysis of the Placenta After Fifteen Compared to Thirty Minutes. A Randomized Controlled Trial.","Inclusion Criteria:\n\n* Term spontaneous vaginal delivery.\n* Singleton Pregnancy.\n* Epidural Analgesia during delivery.\n* Age between 18 and 45 years.\n\nExclusion Criteria:\n\n* Active bleeding after delivery that warrants prompt removal of placenta regardless of time from delivery.\n* Vacuum Extraction.\n* Intrapartum Infection.\n* Intrapartum fever above 38 degrees celsius.\n* Wide 3rd and 4th degree perineal tears that mandate suturing under general anaesthesia.\n* Thalassemia Carriers.",{"count":77,"type":21},100,[24],"Comparison of maternal outcomes following manual lysis of placenta 15 vs 30 minutes after delivery. A primary outcome of the drop in hemoglobin will be compared between the two groups. Secondary outcomes include blood transfusion rate, maternal satisfaction, time to first breastfeeding, length of hospital stay, infection rate etc.",[81],"Third Stage of Delivery",[83],"Manual Lysis, Postpartum Hemorrhage, Third Stage.","2026-08-14",{"date":86,"type":36},"2026-08-17",{"date":88,"type":36},"2026-07-20",{"date":90,"type":21},"2027-08",{"name":42,"class":43},{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":22,"phases":102,"briefSummary":103,"conditions":104,"keywords":106,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":44},"100590102","evaluation-of-blood-loss-after-cesarean-delivery-via-us-compared-to-standard-care-100590102","NCT06963047","Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care","Ultrasound Use Compared With Standard Care for Diagnosis of Blood Loss After Cesarean Delivery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Women who delivered by a cesarean section.\n* Age over 18.\n* Fluent in Hebrew or Arabic.\n* Signed informed consent form.\n\nExclusion Criteria:\n\n* Lack of consent or inability to provide informed consent.\n* Inability to perform a post-surgical ultrasound, such as post-surgery hospitalization in the intensive care unit.\n* Women with preoperative coagulation disorders.\n* Women whose clinical condition requires a post-cesarean ultrasound examination.","50 Years",{"count":101,"type":21},276,[24],"Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are particularly important during the critical period of mother-child bonding. Hemoglobin levels in the first 24 hours after delivery do not reflect the lowest point (nadir). The postpartum nadir occurs 48-72 hours after delivery due to the initial redistribution of plasma volume. The aim of this study was to examine whether postpartum ultrasound examination precedes laboratory test results in the diagnosis of anemia due to blood loss after cesarean section.",[105],"Postpartum Period",[107,108,109,110,111],"Postpartum anemia","Postpartum hemorrhage","Ultrasound","Cesarean section","Intra-abdominal bleeding","2026-06-14",{"date":114,"type":36},"2026-06-16",{"date":116,"type":36},"2025-05-08",{"date":118,"type":21},"2027-06-01",{"name":42,"class":43},{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":127,"enrollmentInfo":128,"targetDuration":130,"studyType":131,"phases":4,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":140,"leadSponsor":142,"locationsCount":44},"100589340","ultrasound-for-assessment-of-intra-abdominal-blood-loss-after-gynecological-surgery-100589340","NCT06953141","Ultrasound for Assessment of Intra-Abdominal Blood Loss After Gynecological Surgery","Ultrasound Use to Estimate the Amount of Intra-abdominal Blood Following Gynecological Surgeries and the Association With Postoperative Outcomes. A Prospective Cohort Study","Inclusion Criteria:\n\n* Women aged 18 years and older\n* Undergoing gynecological surgery including laparotomy, laparoscopy, and vaginal pelvic surgery\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Undergoing minor procedures (e.g., dilation and curettage, hysteroscopy, or cervical conization)\n* Known preoperative coagulation disorders\n* Postoperative admission to the intensive care unit (ICU)\n* Clinical indication requiring ultrasound as part of standard postoperative care","70 Years",{"count":129,"type":21},250,"4 Days","OBSERVATIONAL","This is a prospective cohort study designed to assess intra-abdominal blood volume and hemodynamic status by measuring the diameter of the inferior vena cava (IVC) using 3D and Doppler ultrasound within 24 hours after gynecological surgery. The study will examine the association between these ultrasound findings and postoperative outcomes, including hemoglobin drop, need for blood transfusion, pain, infection, and length of hospitalization. Approximately 250 women undergoing laparotomy, laparoscopy, or vaginal surgery at Holy Family Hospital will be enrolled. The study also aimed to define postoperative normograms for fluid volume and IVC parameters and to evaluate whether ultrasound-guided decision-making could improve postoperative care and reduce unnecessary interventions.",[134,135],"Post-Operative Hematoma at Operative Site (Diagnosis)","Post-Operative Hemorrhage","2026-04-07",{"date":138,"type":36},"2026-04-13",{"date":116,"type":36},{"date":141,"type":21},"2026-12-15",{"name":42,"class":43},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":52,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":152,"briefSummary":153,"conditions":154,"keywords":156,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":164,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":44},"100560682","programmed-intermittent-epidural-bolus-compared-with-continuous-infusion-in-multiparous-women-100560682","NCT06580327","Programmed Intermittent Epidural Bolus Compared With Continuous Infusion in Multiparous Women","Impact of Programmed Intermittent Epidural Bolus Compared With Continuous Epidural Infusion on Breakthrough Pain Among Laboring Multiparous Women. A Randomized Controlled Trial","Inclusion Criteria:\n\n1. multiparous women\n2. Term pregnancy\n3. Singleton\n4. Vertex presentation\n5. Latent phase (cervical dilatation less than 6 cm)\n6. Epidural analgesia request\n7. Visual Analogue Scale score greater than 40\n\nExclusion Criteria:\n\n1. Estimated fetal weight greater than 4.0 kg\n2. Intra uterine fetal death\n3. Drug sensitivity\n\n5\\. Anomalous fetus 6. Contraindication for epidural analgesia",{"count":151,"type":21},186,[24],"The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in multiparous women compared to continuous epidural infusion.\n\nmultiparous women will randomly be divided during labor into two groups; study group will receive mix of Bupivacaine and fentanyl once (bolus) every 60 minutes; the control group will receive continuously the same dose during an hour, until delivery.",[155],"Breakthrough Pain",[157,158,159,160,161,162,163],"multipara","Term pregnancy","Singleton","Vertex presentation","Latent phase","Maternal request for epidural","Visual analogue scale > 4",{"date":138,"type":36},{"date":166,"type":36},"2024-09-25",{"date":168,"type":21},"2026-12",{"name":42,"class":43},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":52,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":182,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":184,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":188,"locationsCount":44},"100554068","pieb-compared-with-cei-on-breakthrough-pain-in-nulliparous-women-100554068","NCT06494280","PIEB Compared With CEI on Breakthrough Pain in Nulliparous Women","Impact of Programmed Intermittent Epidural Bolus Compared With Continuous Epidural Infusion on Breakthrough Pain Among Laboring Nulliparous Women. A Randomized Controlled Trial","Inclusion Criteria:\n\n* Nulliparous women\n* Term pregnancy\n* Singleton\n* Vertex presentation\n* Latent phase (cervical dilatation \\\u003C6 cm)\n* Epidural analgesia request\n* Visual Analogue Scale score \\> 40\n\nExclusion Criteria:\n\n* Estimated fetal weight \\> 4 kg\n* Intra uterine fetal death\n* Drug sensitivity\n* Anomalous fetus\n* Contraindication for epidural analgesia",{"count":178,"type":21},240,[24],"The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in nulliparous women compared to continuous epidural infusion.\n\nNulliparous women will randomly be divided during labor into two groups; study group will receive mix of Bupivacaine and fentanyl once (bolus) every 60 minutes; the control group will receive continuously the same dose during an hour, until delivery.",[155],[183,158,159,160,161,162,163],"Nullipara",{"date":138,"type":36},{"date":186,"type":36},"2024-09-10",{"date":168,"type":21},{"name":42,"class":43},{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":199,"briefSummary":200,"conditions":201,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":203,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":207,"locationsCount":44},"100541834","castor-oil-ingestion-and-balloon-catheter-for-labor-induction-in-multiparous-100541834","NCT06335017","Castor Oil Ingestion and Balloon Catheter for Labor Induction in Multiparous","The Effect of Combining Balloon Catheter With Castor Oil Ingestion for Cervical Ripening on Time to Delivery Among Multiparous Women.","Inclusion Criteria:\n\n* Women above 18 years old\n* Sign an informed consent\n* Term pregnancy (\\>37 weeks)\n* Viable fetus\n* Singleton\n* Vertex presentation\n* Intact membranes\n* Cervix with Bishop score ≤6\n\nExclusion Criteria:\n\n* Previous cesarean delivery\n* Major fetal malformations\n* Contraindication to spontaneous vaginal delivery\n* Amniotic fluid index \\>25cm\n* Chorioamnionitis at admission\n* Placental abruption\n* Previous prostaglandin use for induction of labor\n* A low-lying placenta (up to 2 cm from the internal os)\n* Carriers of hepatitis B or C or human immunodeficiency viruses,\n* Women with a history of allergy to latex.\n* Women with a history of allergy to castor oil","60 Years",{"count":198,"type":21},216,[24],"The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in multiparous women.\n\nThe main question it aims to answer are:\n\nDoes the addition of the use of castor oil to extra-amniotic single balloon reduce the time until birth? Does the addition of the castor oil affect other perinatal outcomes during childbirth? Are the side effects of the castor tolerated by the mothers? Participants will be randomly divided into 2 groups: the study group will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, extra-amniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline.\n\nIn the control group, the catheter will be inserted into cervical canal without ingestion of castor oil.",[202],"Induction of Labor",{"date":138,"type":36},{"date":205,"type":36},"2024-04-10",{"date":168,"type":21},{"name":42,"class":43},{"id":209,"slug":210,"hasResults":11,"nctId":211,"briefTitle":212,"officialTitle":213,"acronym":4,"eligibilityCriteria":214,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":196,"enrollmentInfo":215,"targetDuration":4,"studyType":22,"phases":217,"briefSummary":218,"conditions":219,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":221,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":68},"100541065","castor-oil-ingestion-and-balloon-catheter-for-labor-induction-in-nulliparous-100541065","NCT06325007","Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous","The Effect of Combining Single Balloon Catheter With Castor Oil Ingestion for Cervical Ripening on Time to Delivery Among Nulliparous Women.","Inclusion Criteria:\n\n* Women above 18 years old\n* Sign an informed consent\n* Term pregnancy (\\>37 weeks)\n* Viable fetus\n* Singleton\n* Vertex presentation\n* Intact membranes\n* Cervix with Bishop score ≤6\n\nExclusion Criteria:\n\n* Previous cesarean delivery\n* Major fetal malformations\n* Contraindication to spontaneous vaginal delivery\n* Amniotic fluid index \\>25cm\n* Chorioamnionitis at admission\n* Placental abruption\n* Previous prostaglandin use for induction of labor\n* A low-lying placenta (up to 2 cm from the internal os)\n* Carriers of hepatitis B or C or human immunodeficiency viruses\n* Women with a history of allergy to latex.\n* Women with a history of allergy to castor oil",{"count":216,"type":21},142,[24],"The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in nulliparous women.\n\nThe main question it aims to answer are:\n\nDoes the addition of the use of castor oil to extra-amniotic single balloon reduce the time until birth? Does the addition of the castor oil affect other perinatal outcomes during childbirth? Are the side effects of the castor tolerated by the mothers? Participants will be randomly divided into 2 groups: the study group will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, an extra-amniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline. In the control group, a foley catheter will be inserted into cervical canal without ingestion of castor oil.",[220],"Induction of Labor Affected Fetus \u002F Newborn",{"date":138,"type":36},{"date":223,"type":36},"2024-04-11",{"date":225,"type":21},"2026-12-31",{"name":42,"class":43},""]